Andre P. Seale , PhD
Associate Researcher and ProfessorDepartment of Human Nutrition, Food & Animal Sciences, College of Tropical Agriculture and Human Resources – University of Hawai‘i at Mānoa
Work Email: seale@hawaii.edu
Research Interests
The effects of environmental changes on the physiology (I.e. growth, osmoregulation, metabolism and stress) of aquatic organisms with broader implications to aquaculture and biomedical research.
Recent Publications
- Woo, D. W., Malintha, G. H. T., Celino-Brady, F. T., Yamaguchi, Y., Breves, J. P., Seale, A. P. (2022). Tilapia prolactin cells are thermosensitive osmoreceptors. Am. J. Physiol. https://doi.org/10.1152/ajpregu.00027.2022.
- Seale, L. A., Gilman, C. L., Zavacki, A. M., Larsen, P. R., Inokuchi, M., Breves, J. P., Seale, A. P. (2021) Regulation of thyroid hormones and branchial iodothyronine deiodinases during freshwater acclimation in tilapia. Mol. Cell. Endocrinol. 538: 111450.
- Inokuchi, M., Moorman, B., Yamaguchi, Y., Seale, A. P. (2021). Age-dependent decline in salinity tolerance in a euryhaline fish. Front. Aging. 2: 15.
- Celino-Brady, F., Lerner, D. T., Seale, A. P. (2021). Experimental Approaches for Characterizing the Endocrine Disrupting Effects of Environmental Chemicals in Fish. Front. Endocrinol. 11:1170
- Seale, A. P., Pavlosky, K. K., Celino-Brady, F., Lerner, D. T. (2020). Sex, salinity and sampling period dependent patterns of growth hormone mRNA expression in Mozambique tilapia. Aquaculture. 519: 734766.
- Seale, A. P., Pavlosky, K. K., Celino-Brady, F., Yamaguchi, Y., Breves, J. P., Lerner, D. T. (2019). Systemic versus tissue-level modulation of prolactin signaling in a euryhaline teleost subjected to tidally changing salinities. J. Comp. Physiol.189, 581-594.
Recent Grants
- 2022-present PI: University of Hawai‘i Sea Grant College Program omnibus grant; “Identifying the physiological responses to extreme environmental changes in native Hawaiian Sea cucumbers found in traditional fishponds”;
- 2019-present Co-PI: Advanced Aquaculture Collaborative Programs (NOAA); “Establishing a Hawaiʻi-Pacific Aquaculture Consortium: A Revitalization and Expansion of the Aquaculture Development Program”.
- 2018-present Co-PI; Department of Commerce, National Oceanic and Atmospheric Administration (NOAA); “Establishing an aquaculture program at the University of Hawai‘i that leverages and integrates Land Grant and Sea Grant research, extension and education resources.
- 2018-present PI; National Science Foundation (IOS-1755016); “Collaborative Research: Identifying osmosensitive molecular targets using a unique vertebrate model”.
- 2017-2021 PI; National Institutes of Health (1R21DK111775-01); “Integrating Osmosensitivity and Autocrine Signaling in a Model for Osmoregulation”.
Current Graduate Students
- Tharindu Malintha (PhD, Nutritional Sciences), Environmental regulation of transcription factors in fish.
- Ryan Chang (MS, Animal Science), Effects of salinity on the stress response in fish.
- Tyler Goodearly (PhD, Nutritional Sciences), Environmental physiology of Sea Cucumbers.
- Reilly Merlo (MS, Animal Science), Effects of salinity on fish nutrition.