Associate Research Professor and Director Nutrition Support Shared Resource, University of Hawai‘i Cancer CenterUniversity of Hawai‘i Cancer Center – University of Hawai‘i at Mānoa
Work Email: cjboushey@cc.hawaii.edu
Research Interests
Nutritional epidemiology, dietary assessment, interventions, biomarkers of dietary intake.
Recent Publications
- Kelkar S, Boushey CJ, Okos M. A method to determine the density of foods using X-ray imaging. J Food Eng 2015; 159: 36-41. PMID 25848138.
- Harmon BE, Boushey CJ, Shvetsov YB, Ettienne R, Wilkens LR, Le Marchand L, Henderson BE, Kolonel LN. Associations of Key Diet Quality Indexes with Mortality in the Multiethnic Cohort: The Dietary Patterns Methods Project. Am J Clin Nutr 2015; 101(3):587-97. PMID: 25733644.
- Fialkowski MK, Ettienne R, Shvetsov YB, Rivera RL, Van Loan MD, Savaiano DA, Boushey CJ. Ethnicity and acculturation: do they predict weight status in a longitudinal study among Asian, Hispanic, and non-Hispanic White early adolescents? Adolesc Health Med Ther 2015; 6:1-7. PMID: 25624775.
Recent Grants
- NIEH/NIH 2005-2016. Domoic acid neurotoxicity in Native Americans.
- NIH/NCI 2013. Dietary patterns methods project.
Adrian Franke PhD
Director, Analytical Biochemistry Shared Resource and Professor, Natural Products and Experimental Therapeutics ProgramUniversity of Hawai‘i Cancer Center- University of Hawaii at Manoa
Work Phone: 808.586.3008 Work Email: adrian@cc.hawaii.edu
Research Interests
Development of biomarkers reflecting exposure to vegetarian foods, pharmacokinetics of chemopreventive micronutrients, development of state-of-the-art analytical techniques to determine metabolites in biological matrices.
Recent Publications
- Franke AA, Custer LJ, Morrison CM, Li X, Lai JF. (2013).Simultaneous analysis of circulating 25-hydroxy-vitamin D3, 25-hydroxy-vitamin D2, retinol, tocopherols, carotenoids, and oxidized and reduced coenzyme Q10 by HPLC with photo diode-array detection using C18 and C30 columns alone or in combination.J Chromatogr, 1301, 1-9 A.
- Franke AA, Lai JF, Morrison CM, Pagano I, Li X, Halm BM, Soon Rand Custer LJ. (2013).Coenzyme Q10, carotenoid, tocopherol, and retinol levels in cord plasma from multiethnic subjects in Hawaii. Free Radic Res, 47(9), 757-768.
Recent Grants
- U54 NCI. Identification of biomarkers in saliva for betel nut consumption. 07/01/13 – 06/30/14
- PO1 NIH/NCI. Project 1:nutritional, biochemical, and hormonal predictors. Obesity, body fat distribution and cancer risk in the multiethnic cohort. 04/01/012-03/31/17
- R01 NIH/NCI. Urinary Isoflavonoids and Stroke Risk in Chinese Women. 02/01/11-01-31/14
Cancer Epidemiology ProgramUniversity of Hawai‘i Cancer Center – University of Hawai‘i at Mānoa
Work Email: loic@cc.hawaii.edu
Research Interests
The interactions between genetic and lifestyle factors responsible for the cancer risk differences that exist among ethnic/racial groups in Hawaii and California, with the goal of advancing our understanding of the causes, mechanisms and prevention of cancer.
Recent Publications
- Wang H…Le Marchand L. (2014). Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. Nat Commun. 2014 Aug 8;5:4613. doi: 10.1038/ncomms5613. This is a modified citation.
- Park SL…Le Marchand L. (2014). Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia. J Natl Cancer Inst. 2014 Apr 1;106(4):dju061. doi: 10.1093/jnci/dju061. Epub 2014 Mar 28. This is a modified citation.
- Cheng I…Le Marchand* L. (2013). Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia. Gut. 2013 Aug 9. doi: 10.1136/gutjnl-2013-305189. [Epub ahead of print] *Co-senior author. This is a modified citation.
Recent Grants
- L. Le Marchand, C. Henderson, L. Wilkens, MPIs, UM1 CA164973, National Cancer Institute, "Understanding Ethnic Differences in Cancer: The Multiethnic Cohort Study" 2012–2017.
- L. Le Marchand, PI. P01 CA169530, National Cancer Institute, "Obesity, Body Fat Distribution and Cancer Risk in the Multiethnic Cohort" 2012–2017.
- L. Le Marchand, PI of subcontract, (Haile/Lindor/Jenkins, MPIs), U01 CA167551, National Cancer Institute, "The Colon Cancer Family Registry Cohort" 2012–2016.
- C. Haiman/L. Le Marchand, MPIs, National Human Genome Research Institute, "Epidemiology of Putative Causal Variants in the Multiethnic Cohort" 2013-2017.
Professor, Cancer Epidemiology Program and Program Director, Post-Doctoral Training ProgramUniversity of Hawai‘i Cancer Center – University of Hawai‘i at Mānoa
Home Phone: 808.586.3078
Research Interests
Preventive medicine and nutritional epidemiology, etiology of breast cancer, Non-Hodgkin Lymphoma (NHL), and type 2 diabetes.
Recent Publications
- Maskarinec G, Harmon BE, Melissa AL, Ollberding, NJ, Kolonel LN, Henderson BE, Le Marchand L, Wilkens LR. (2015). Excess Body Weight and Colorectal Cancer Survival: The Multiethnic Cohort. Cancer Causes and Control 26: 1709-18. Sep 10. [Epub ahead of print]. PMCID: 4628582.
- Leo QJN, Ollberding NJ, Wilkens LR, Kolonel LN, Henderson BE, Le Marchand L, Maskarinec G (2015). Nutritional Factors and Non-Hodgkin Lymphoma Survival in an Ethnically Diverse Population: The Multiethnic Cohort Study. European Journal of Clinical Nutrition, September 2, 2015; doi:10.1038/ejcn.2015.139. PMCID: 4562319.
- Morimoto Y, Maskarinec G, Park SY, Ettienne R, Matsuno RK, Long C, Steffen AD, Henderson BE, Kolonel LN, Le Marchand L, Wilkens LR. (2014). Dietary isoflavone intake is not associated with breast cancer risk in the Multiethnic Cohort. British Journal of Nutrition 112:976-83; 23 July. [Epub ahead of print]. PMCID: 4237401.
Recent Grants
- G. Maskarinec, Program Director; J. Hedges, (PI: J. Hedges), P30 CA071789-14S1, University of Hawaii Cancer Center CCSG CURE Supplement. 07/2013 - 06/2017.
- G. Maskarinec, Co-Investigator, (PIs: L. Le Marchand/U. Lim), P01 CA168530, "Obesity, Body Fat Distribution, and Cancer Risk in the Multiethnic Cohort" 09/01/12 - 08/31/17.
- G. Maskarinec, Multiple PI of Education Core, U54 CA143727, "University of Guam/University of Hawaii Cancer Center Partnership Education Core" 09/01/15 – 08/31/20.
Researcher R5Population Sciences in the Pacific Program (Cancer Epidemiology), University of Hawai‘i Cancer Center
Work Email: johnshep@hawaii.edu
Research Interests
Radiomic biomarker discovery using AI and deep learning, 3D optical shape and appearance modeling, Director - UHCC Artificial Intelligence Precision Health Institute, reducing the burden of disease by translating biomarkers from expensive invasive to accessible technologies and measures.
Recent Publications
- Shepherd JA, Sommer MJ, Fan B, Powers C, Stranix-Chibanda L, Zadzilka A, Basar M, George K, Mukwasi-Kahari C, Siberry G. Advanced Analysis Techniques Improve Infant Bone and Body Composition Measures by Dual-Energy X-Ray Absorptiometry. J Pediatr. 2017 Feb;181:248-253.e3. PMCID: PMC5274603.
- Shepherd JA, Ng BK, Sommer MJ, Heymsfield SB. Body composition by DXA. Bone. 2017 Nov;104:101–105. PMCID: PMC5659281.
- Shepherd JA, Ng BK, Fan B, Schwartz AV, Cawthon P, Cummings SR, Kritchevsky S, Nevitt M, Santanasto A, Cootes TF. Modeling the shape and composition of the human body using dual energy X-ray absorptiometry images. PLoS One. 2017;12(4):e0175857. PMCID: PMC5397033.
- Shepherd JA, Fan B, Lu Y, Wu XP, Wacker WK, Ergun DL, Levine MA. A multinational study to develop universal standardization of whole-body bone density and composition using GE Healthcare Lunar and Hologic DXA systems. J Bone Miner Res. 2012 Oct;27(10):2208–2216. PMID: 22623101.
Recent Grants
- NIH/NCI 03/06/13 - 02/28/19. Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis.
- NIH/NIDDK 5/15/16 - 4/30/21. Optical Body Composition and Health Assessment.
- NIH/NIDDK 10/1/2016 - 9/30/2021. Shape Up! Kids.
- NIH/NIEHS 9/30/15 – 6/30/20. Environmental Chemicals and Postpubertal Breast Composition in a Latino Cohort.
- CDC 05/21/18 – 05/20/19. Dual Energy X-ray Absorptiometry (DXA) Scan Analysis and Quality Control Review for NHANES 2018-2022.
- General Electric 08/1/18 – 07/31/20. Quantitative Tomosynthesis Imaging
- NIH/NAIAD 06/29/06 – 11/30/20. LOC-IMPAACT Leadership Group.
Current Graduate Students
- Wong, Michael (PhD Nutrition)
- Valdez, Dustin (PhD Nutrition)
- Bennett, Jon (PhD Nutrition)
- Spence, Shane (MS in EE)
- Leong, Lambert (PhD MBBE)
- Cataldi, Devon (PhD Kinesiology).
Lynne Wilkens DrPH, MS
Co-Director, Biostat and Informatics Shared ResourceUniversity of Hawai‘i Cancer Center- University of Hawaii at Manoa
Work Email: lynne@cc.hawaii.edu
Research Interests
Methodological research that extends statistical techniques of relevance to our research, techniques for studying disease associations when the independent variables are measured with error and ethical/racial classification.
Recent Publications
- Wang H, Schmit SL, Haiman CA, Keku TO, Kato I, Palmer JR, van den Berg D, Wilkens LR, Burnett T, Conti DV, Schumacher FR, Signorello LB, Blot WJ, Zanetti KA, Harris C, Pande M, Berndt SI, Newcomb PA, West DW, Haile R, Stram DO, Figueiredo JC, Le Marchand L. Hispanic Colorectal Cancer Study. Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. Int J Cancer. 2017 Mar 13. doi: 10.1002/ijc.30687. [Epub ahead of print]
- Harmon BE, Wirth MD, Boushey CJ, Wilkens LR, Draluck E, Shivappa N, Steck SE, Hofseth L, Haiman CA, Le Marchand L, Hébert JR. The Dietary Inflammatory Index Is Associated with Colorectal Cancer Risk in the Multiethnic Cohort. J Nutr. 2017 Mar;147(3):430-438. doi: 10.3945/jn.116.242529.
- Conroy SM, Clarke C, Yang J, Shariff-Marco S, Shvetsov YB, Park SY, Albright CL, Hertz A, Monroe KR, Kolonel LN, Le Marchand L, Wilkens LR, Gomez SL, Cheng I. Contextual impact of neighborhood obesogenic factors on postmenopausal breast cancer: The Multiethnic Cohort. Cancer Epidemiol Biomarkers Prev. 2017 Jan 31. pii: cebp.0941.2016. doi: 10.1158/1055-9965.EPI-16-0941. [Epub ahead of print]
