Kate Larson , PhD
Affiliate Graduate FacultyDepartment of Human Nutrition, Food and Animal Sciences, College of Tropical Agriculture and Human Resources – University of Hawai‘i at Mānoa
Work Email: klarson7@hawaii.edu Personal Email: kate.claycombe@gmail.com
Research Interests
Nutritional Immunology, Nutritional Epigenetics, Maternal Dietary Effects on Offspring Obesity, and Indigenous Diet and Inflammatory Diseases.
Recent Publications
- Claycombe-Larson KJ, Bundy AN, Kuntz T, Hur J, Yeater KM, Casperson S, Brunelle DC, Roemmich JN., Effect of a maternal high-fat diet with vegetable substitution on fetal brain transcriptome, J Nutr Biochem. 2022 Oct;108:109088. doi: 10.1016/j.jnutbio.2022.109088
- Claycombe-Larson K, Singh B, Bundy AN, Brunelle D, Bukowski MR, Roemmich JN, J Nutr Biochem. 2022 Oct 13;114:109162. doi: 10.1016/j.jnutbio.2022.109162.
- Bukowski MR, Singh BB, Roemmich JN, Claycombe-Larson KJ, Lipidomic Analysis of TRPC1 Ca2+-Permeable Channel-Knock Out Mouse Demonstrates a Vital Role in Placental Tissue Sphingolipid and Triacylglycerol Homeostasis Under Maternal High-Fat Diet., Front Endocrinol (Lausanne). 2022 Mar 10;13:854269. doi: 10.3389/fendo.2022.854269.
- Claycombe-Larson KJ, Bundy A, Lance EB, Darland DC, Casperson SL, Roemmich, J., Postnatal exercise protects offspring from high-fat diet-induced reductions in subcutaneous adipocyte beiging in C57Bl6/J mice, J Nutr Biochem. 2022 Jan;99:108853. doi: 10.1016/j.jnutbio.2021.108853.
- Crouse MS, Caton JS, Claycombe-Larson KJ, Diniz WJS, Lindholm-Perry AK, Reynolds LP, Dahlen CR, Borowicz PP, Ward AK, Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Divergent Energy Supply. Front Genet. 2022 Feb 24;13:812764. doi: 10.3389/fgene.2022.812764.
Recent Grants
- NIH COBRE, Historical trauma and resilience as a biological state and its association with the effects of the traditional Indigenous food chokeberry, UND, 2021-2026, Co-Investigator
- NIH COBRE, Stress and Health in American Indian Pregnancies, UND, 2021-2026, Co-Investigator
- USDA Agricultural Research Service Project #3062-51000-054-00D, 2019-2024, PI
- USDA NIFA, Maternal Nutrition, Epigenetic Modifiers, And Programming Of Fetal Organ Development In Beef Cattle, 2019-2014, Collaborator
- NIH COBRE Epigenomics of Development and Disease, UND, 2019-2024, Collaborator
- USDA NIFA, Synergistic effects of omega 3 polyunsaturated fatty acids and anthocyanins in inflammation-associated obesity and insulin resistance, 2018-2023, Consultant
- USDA Agricultural Research Service Project #3062-51000-052-00D, 2014-2019, PI