Rigorous, in-depth introduction to chemical principles with emphasis on experimental and applied aspects of modern chemistry. Students who successfully completed 161 or 171 with a grade of C or better will not be allowed to enroll in 181A without instructor override. Students who successfully complete 181A with a grade of C or better will not be allowed to enroll in 161 or 171 without instructor override. Pre: satisfactory placement exam score and MATH 215 (or concurrent) or MATH 241 (or concurrent) or MATH 251A (or concurrent) with a minimum grade of C. (Fall only)