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John A. Burns School of Medicine

ANAT 499 Directed Reading/Research (V)

ANAT 545 (Alpha) Unit VII Anatomy Electives (V)

Advanced study of human anatomy by dissection and individual observation of surgical procedures. (C) topics in reproductive biology. Repeatable two times. CR/NC only. Pre: FMCH, MED, OBGN, PED, PSTY, SURG 531 or 532; or consent.

ANAT 599 Independent Study in Anatomy (1)

Elective course for advanced medical students. (B) human gross anatomy; (C) histology; (D) research in anatomy and developmental biology. CR/NC only. Repeatable three times. Pre: consent for (B) and (C); MDED 551 for (D).

ANAT 603 Lower Extremity, Thorax, and Abdomen (3)

Human gross anatomy dissection of the lower extremity, thorax, and abdomen. Emphasis is placed on muscles, function, innervation, and vascular supply. Repeatable one time. Enrolled in DRB or KRS graduate programs (including Biomed Sci-Anat/ RepoBiol & Phys majors) only or consent. A-F only. (Spring only) (Cross-listed as KRS 603)

ANAT 604 Upper Extremity, Head, Neck, and Spine (3)

Human gross anatomy dissection of the upper extremity, head, neck, and spine. Emphasis is placed on muscles, function, innervation, and vascular supply. Repeatable one time. Enrolled in DRB or KRS graduate programs (including Biomed Sci-Anat/ RepoBiol & Phys majors) only or consent. A-F only. (Fall only) (Cross-listed as KRS 604)

ANAT 607 Human Embryology (2)

Systematic study of human development, including implantation, placentation, basics of development of each organ system with reference to pertinent congenital anomalies and their surgical repair. Pre: 603 or 604. Recommended: gross anatomy course.

ANAT 612 Seminar in Anatomy Teaching (V)

Effective teaching methods, organization of courses in anatomical sciences, development and evaluation of exams, experience in teaching with audiovisual/ computer aids. Open to graduate students in physiology or KRS. CR/NC only. Repeatable eight times, up to 32 credits. Pre: 603 and 604.

ANAT 699 Directed Research (V)

Repeatable unlimited times.

ANAT 700 Thesis Research

Repeatable unlimited times. (V) Pre: admission to candidacy (master’s program).

ANAT 800 Dissertation Research (V)

Repeatable unlimited times.

BIOC 241 Fundamentals of Biochemistry (3)

Biological chemistry stressing integration of concepts of general, inorganic, and biochemistry and application to life chemistry. Pre: beginning algebra and high school science.

BIOC 341 Elements of Biochemistry (3)

Biochemical principles and concepts as applied to living systems, including sufficient organic chemistry to understand these principles. Pre: 241 or consent.

BIOC 441 Basic Biochemistry (4)

Principles of biochemistry, applicable to medicine and real-life situations, involving metabolism of carbohydrates, lipids, proteins, nucleic acids, and vitamins. Taught by biomedical researchers. Evaluated based on exams, quizzes, homework, and group presentation.

BIOC 499 Directed Research and Reading (V)

Independent research or selected reading of current literature in the area of biochemistry and biophysics. Repeatable unlimited times. Pre: consent.

BIOC 545 Topics in Biochemistry (V)

Fourth-year elective in which medical students take an in-depth study of selected topics in biochemistry. Pre: fourthyear medical student or consent.

BIOC 595 Highlights of Organ-System Biochemistry (1)

Provides highly interactive, small group discussions on concepts of biochemistry important to the various organ systems; such as cardiac, respiratory, hematology, gastrointestinal, endocrine, musculoskeletal and neurological systems, and relevant to clinical medicine. MD majors only. CR/NC only. Pre: MDED 554. (Fall only)

BIOM 499 Directed Research and Reading (V)

To provide elective courses for undergraduates in the biomedical sciences specialties. Repeatable unlimited times

BIOM 601 Global Health and Medicine: Emerging Problems and Impact (3)

Analysis of emerging problems and impact in countries on a multidimensional perspective. Repeatable one time. BIOM, NURS, PH, SPA majors only. Pre: consent.

BIOM 640 Introduction to Clinical Research (3)

Instruction in developing clinical research questions and creating a concise protocol that includes a literature review, study design, subject recruitment and sampling, instruments, other measures and bioinformatics, sample size, consent form, budget and timetable. A-F only.

BIOM 641 Legal and Regulatory Issues and Bioethics (2)

Ethical dilemmas in clinical research are identified and resolved in cases, research on human subjects regulation are discussed. Research misconduct is defined. Ethical considerations in protocol developed in the Designing Clinical Research course are resolved. A-F only. (Cross-listed as CMB 626)

BIOM 644 Translational Research Methods (2)

Lectures focus on translational research methods through selected genetic and acquired diseases including cancer, neurodevelopmental, inflammatoryimmune, and metabolic conditions with insight into analyses of DNA, RNA, genomics-proteomics, cell and animal models, and advanced imaging. A-F only. Pre: consent.

BIOM 645 Clinical Protocol Development (3)

Provides training in proposal development. Governance structures of funding agencies; funding opportunities and decisions; review processes; NIH application and processes; reading RFAs; compliance issues; cultural sensitivity; and types of questions using databases are addressed. A-F only.

BIOM 646 Clinical Research Seminar (1)

Provides overview of research related to health and health disparities in Hawai‘i. Seminar topics include ethnic disparities in health research, Native Hawaiian health, childhood research initiatives, fitness and obesity, social and cultural factors and ethics. Repeatable six times. A-F only. Pre: consent.

BIOM 647 Cultural Competence in Biomedical Research I (3)

Introductory lecture-seminar on the conduct of multidisciplinary research from a culturally competent perspective. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)

BIOM 648 Foundations of Biomedical Ethics (3)

Explores the foundations of biomedical ethics via small group seminars and discussion, presentations. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)

BIOM 649 Advanced Ethics in Biomedical Research II (3)

Develop biomedical ethics through case studies to incite discussions on topics such as gene therapy, gene enhancement, genetic counseling, informed consent, health care professional/patient and investigator/student participant communication, advanced directives and living wills, clinical research in developing countries, clinical research in ethnic minority and socio-economically disadvantaged populations, and non-discrimination in health care and research settings. A-F only.

BIOM 650 Cultural Competence in Biomedical Research II (3)

Explore topics in cultural competence in greater depth, encouraging trainees to address issues from a unified yet flexible conceptual framework. Involves building knowledge, skills and action plans to address a range of learning styles and to appreciate and benefit from diversity. A-F only.

BIOM 651 PhD Team Building Seminar (V)

Seminar focuses on teaching participants to work independently and collaborate in order to accomplish specific results. Students will be exposed to group dynamics, communication, healthy competition, conflict resolution, and innovative means of crossing boundaries between departments, organizations, industries and disciplines. Repeatable two times. A-F only.

BIOM 654 Medical Genetics (2)

Focus on heritable disorders, genetic mechanisms, patterns of inheritance, phenotype-genotype correlations, genetic/ environmental factors, clinical diagnoses, genomic and precision medicine.

BIOM 660 Mentored Research Practicum (V)

Conduct research under the direction of a mentor. Participants will be responsible for submission of a proposal, acquisition of IRB approval, and conduct of the project. Repeatable five times or up to 12 credits. BIOM students only. A-F only.

BIOM 667 Advanced Biostatistics for Clinical Research (3)

Current methods for analyzing longitudinal and clustered, clinical data through lectures, discussions, and a group analysis. Topic areas include multi-level, multi-state, multi-process, and structural equation models. A-F only. Pre: 642 and 643, or consent.

BIOM 699 Directed Research (V)

Students may register on approval of department. CR/NC only. Repeatable unlimited times.

BIOM 700 Thesis Research (V)

Research for master’s thesis. Repeatable unlimited times. CR/NC only. Pre: consent.

BIOM 701 Disasters and Pandemics: Medical and PH Management and Risk Communication (3)

Assess impact on health in disasters and diseases. Enhances research skills related to management and communication. Repeatable one time. BIOM, PH, NURS, and SPA majors only. Pre: consent.

BIOM 800 Dissertation Research (V)

Research for doctoral dissertation. Repeatable unlimited times. CR/ NC only. Pre: consent.

CAAM 401 Mindfulness Meditation and Stress Reduction (1)

Practice mindfulness meditation to reduce burnout and live life in the present moment. Learn life skills to handle life better and be more resilient. Respond rather than react to life. No experience necessary. Repeatable nine times.

CAAM 415 Clinical Nutrition (3)

Overview of applied clinical nutrition that includes nutrients, dietary recommendations for healthy populations, and medical nutrition therapies for patients with diet related diseases or conditions. Repeatable one time. Junior standing and higher. Pre: CHEM 151 (or higher) or BIOC 241 (or higher); PHYL 141 or ZOOL 141; highly encouraged: FSHN 185 or any other basic nutrition course.

CAAM 445 Introduction to Integrative Medicine (3)

Overview of integrative (complementary) medicine covering Traditional Chinese Medicine, Ayurvedic medicine, naturapathy, traditional healing practices, homeopathy, nutrition and diet, herbs and dietary supplements, environmental health, mind-body, energy, spiritual, and positive psychology. Repeatable one time. Junior standing or higher.

CAAM 595 Nutrition for Clinicians (1)

Provides in-depth lectures and case studies reviewing the role of nutritional therapy in health and illness. MD majors only. CR/NC only. Pre: MDED 554 or consent. (Fall only)

CAAM 599 Research Topics in Complementary and Alternative Medicine (V)

Research elective for medical students. MD students only. CR/NC only. Pre: MDED 554 or consent. (Fall only)

CMB 351 Genetics, Evolution and Society (3)

The role of genetics in evolution, medicine, behavior, plant and animal breeding and technology; its impact on today’s society. Pre: one semester of biological science at college level or consent. Not a BIOL major elective. (Cross-listed as BIOL 340)

CMB 411 Human Genetics (3)

Principles of human genetics. Designed for pre-medical or pre-dental students or others who require a course with emphasis on human genetics. Pre: BIOL 172 and BIOL 172L, or consent.

CMB 499 Genetical Problems (V)

Directed reading and research in genetics. Repeatable unlimited times. Pre: 351 or 411.

CMB 515 Unit V Topics in Genetics (1)

First-year elective course in which medical students may take an in-depth study of genetics. Repeatable six times. Pre: first-year medical student or consent.

CMB 526 Bioethics (1)

Prepare medical students to identify and resolve ethical dilemmas in medical career and biomedical research, and to maintain integrity and professionalism in accordance with relevant ethical principles, policies, and laws. Repeatable one time. MD majors only. CR/NC only.

CMB 599 Research Topics in Cell Molecular Biology (V)

Research elective for medical students. MD majors only. CR/NC only. Pre: MDED 551 and consent.

CMB 604 Evolutionary Genetics (2)

Genetic changes involved in the processes of adaptation and in species formation. Pre: 411. Recommended: population and/or quantitative genetics.

CMB 606 Introduction to Neurosciences (4)

An interdisciplinary overview of the central nervous system, drawn from current knowledge and research on vertebrate and invertebrate neurobiology. Repeatable one time. Pre: consent.

CMB 610 Public Health Biology (3)

Writing intensive asynchronous computer-based course examines biological processes and challenges relevant to the public health professional. Topics include anatomical, pathophysiological, and molecular bases of public health; genetics, immunology, ethics; disease prevention, control, and management. (Once a year) (Cross-listed as PH 610)

CMB 611 Seminar in Biomedical Sciences (1)

Presentation and discussion of research topics in biomedical science. Repeatable nine times. CR/NC only. Pre: graduate standing or consent. (Cross-listed as REPR 611)

CMB 621 Cell Molecular Biology I (4)

Molecular approaches to cell structure and function emphasizing cells in multi-cellular plants and animals. Pre: BIOL 402 or MBBE 402; and BIOC 441, BIOL 408, and graduate standing; or consent. Recommended: CHEM 351.

CMB 622 Cell Molecular Biology II (4)

Molecular approaches to cell structure and function emphasizing cells in multi-cellular plants and animals. Pre: 621, BIOC 441, and BIOL 408; and either BIOL 402 or MBBE 402; or consent.

CMB 625 Advanced Topics in Genetics (2)

Advanced treatment of frontiers in genetics. Pre: graduate standing in genetics or consent.

CMB 626 Ethics in Biomedical Research (2)

Topics include responsible data management, recording, reporting, misconduct and scientific fraud, conflicts of interest, critical use of animals and human issues and subjects in research, genetic screening, stem cell and gene therapy and patenting. (Cross-listed as BIOM 641)

CMB 631 Research Rotations (3)

Individualized research project in three laboratories of CMB faculty with a written report on each project. Faculty laboratories will be selected by consultation with student’s graduate committee and individual faculty. Repeatable two times. Pre: 621 (or concurrent), 622 (or concurrent); or consent.

CMB 640 Neuropharmacology (2)

Physiology and pharmacology of central and peripheral nervous systems, focusing on synaptic chemistry and signaling. A-F only. Pre: 606, or consent from the course director. (Cross-listed as PHRM 640)

CMB 641 Introductory Biostatistics for the Bench Biologist (3)

Lecture and example-based introduction to the critical biostatistics skills commonly required of the bench life scientist. Technical literacy and basic practical application are the goals. Problem sets will be scored. A-F only. (Spring only)

CMB 642 Introductory Bioinformatics for the Bench Biologist (3)

Modern biomolecular and genomic concepts are explored through brief guided hands-on web-based bioinformatic projects using public domain resources. Understanding key concepts and algorithms, technical literacy, and operational confidence are goals. Programming skill development is student-optional. A-F only. (Fall only)

CMB 650 Population Genetics (3)

Mathematical, observational, experimental results on effects of mutation, selection, and systems of mating on distribution of genes. Analysis of non-experimental populations. Pre: consent. (Cross-listed as BIOL 650)

CMB 652 Literature Analysis and Scientific Writing (2)

Aims to improve the skills of graduate students in Biomedical Sciences in literature search, analysis, and management, as well as in scientific writing and other forms of scientific communication. Graduate students only or consent. A-F only. (Fall only)

CMB 654 (Alpha) Genetics Seminar (1)

Research and topical literature reports in genetics. May be repeated. (B) molecular genetics; (C) molecular biology of cancer; (D) human genetics; (E) cytogenetics; (F) evolutionary genetics; (G) molecular biology of the cell; (H) drosophila genetics; (I) population/statistical genetics; (J) developmental genetics; (K) insect molecular biology; (M) genetics and molecular biology of fungi. Repeatable unlimited times for (G). Pre: graduate standing in genetics or consent.

CMB 669 Essentials in Grant Writing (2)

(1 2-hr Lec) Presentation and discussion of hypothesis-driven research and grant writing. Topics include the process of proposal, submission, and review. Course work includes writing, critiquing, and revising a proposal. Graduate students only. Repeatable two times. CR/ NC only. Pre: recommended 626 and consent.

CMB 671 Techniques in Genetics (V)

Laboratory training in procedures used in diagnosis of genetic diseases, cytogenetics, immunogenetics, and dermatoglyphics. Repeatable three times. Pre: graduate standing in genetics or consent.

CMB 672 Techniques in Genetics (3)

Continuation of 671.

CMB 699 Directed Research (V)

Repeatable unlimited times. Pre: graduate standing and consent.

CMB 700 Thesis Research (V)

Research for master’s thesis. Repeatable unlimited times. Pre: acceptance of thesis topic.

CMB 705 Special Topics in Neurosciences (V)

Advanced topics in neuroscience, from basic neurobiology to clinical neurology and psychiatry. Emphasis on current investigations at the cellular or molecular level. Repeatable unlimited times. Pre: consent.

CMB 800 Dissertation Research (V)

Repeatable unlimited times. Pre: acceptance of dissertation topic.

CSD 431 Anatomy and Physiology of the Speech and Hearing Mechanism (3)

Will overview anatomy and physiology of speech and hearing. Students gain exposure to structures and functions of respiration, phonation, resonance, articulation, deglutition, and hearing systems required for normal communication and swallowing. Repeatable unlimited times. A-F only. (Fall only)

CSD 432 Phonetics (3)

Introduction to the fundamentals of phonetic and phonological development. International Phonetic Alphabet Transcription of English speech sounds; phonological developments and models; cultural variations; analysis interpretation and other considerations related to speech sound development and production. Repeatable unlimited times. A-F only. (Fall only)

CSD 433 Speech and Language Development (3)

Will develop an understanding of children’s acquisition of speech, language, and normal communication development from birth through adolescence. Repeatable unlimited times. A-F only. (Fall only)

CSD 434 Acoustics and Psychoacoustics of Speech and Hearing (3)

Provides an understanding of the fundamental processes underlying the production and perception of speech. Students gain an understanding of the physical and psychological aspects of sound and their measurement. Repeatable unlimited times. A-F only. (Spring only)

CSD 435 Introduction to Clinical Methods in Communication Sciences and Disorders (3)

Provides observation and discussion of the clinical management of individuals with communication disorders, and practical experience related to clinical procedures and requirements. Repeatable unlimited times. A-F only. (Spring only)

CSD 436 Introduction to Communication Sciences and Disorders (3)

Information and theoretical foundations serve as an introduction to the field of communication disorders. Will provide an overview of the normal processes and disorders of speech, language, hearing, and swallowing. Repeatable unlimited times. A-F only. (Spring only)

CSD 437 Introduction to Audiometry and Auditory Disorders (3)

Covers anatomy and physiology of the auditory system, acoustic, basic knowledge of auditory disorders and testing procedures, and introduction to rehabilitative audiology. Repeatable unlimited times. A-F only. (Summer only)

CSD 438 Basic Statistics for Health-Related Professionals (3)

Provides students from behavioral sciences and health-related professions with an overview of normal distribution, central tendency, variability, sampling, hypothesis testing, frequency distribution, correlation, regression, and t-test. A-F only. (Spring only)

CSD 600 Research Methods (3)

Research methods applicable to the field of speech-language pathology and audiology; analysis and reporting of data. Required of all CSD graduate students. Pre: previous coursework in inferential statistics and consent.

CSD 601 Neuroscience in Communication Sciences and Disorders (3)

Explores the neuroanatomy and neurophysiology of the human nervous system as it relates to communication and swallowing and how neurological pathologies lead to behavioral deficits in those areas. CSD majors only. A-F only. (Fall only)

CSD 603 Audiological Foundations for SpeechLanguage Pathology (3)

Instrumentation; special tests of hearing.

CSD 604 Seminar in Motor Speech Disorders (3)

Provides in-depth examination of various motor speech disorders, including apraxia of speech and dysarthria. Emphasis is on assessment/treatment of these diagnoses. Review of current treatment literature, anatomy/physiology, practical exercises in treatment planning. A-F only. Pre: consent.

CSD 610 Disorders of Phonology and Articulation (3)

Study of the etiology, assessment, and remediation of disorders and articulation. A-F only.

CSD 612 Child Language Disorders (3)

Study of the etiology, behavioral characteristics and treatment methods for child language disorders. Examination of methods, test, and instruments employed in diagnosis of child language disorders. Includes identification of language deficits and writing intervention goals. A-F only. Pre: consent.

CSD 613 Language Development for Children with Hearing Deficiencies (3)

Language acquisition by hard-of-hearing and deaf children; methods of stimulating growth. Pre: consent.

CSD 616 Advanced Practicum in Speech Pathology I (3)

Clinical practice in diagnostic and therapeutic procedures with various types of speech and language problems in different clinical settings. Repeatable unlimited times, credit earned for six credits only.

CSD 617 Audiology Practicum for SpeechLanguage Pathology (1)

Clinical practice in administering tests, interpreting results; counseling of individuals with impaired hearing; use of various rehabilitation techniques. Repeatable unlimited times. Pre: consent.

CSD 620 Voice Disorders (3)

Contemporary development and theoretical issues in the diagnosis, evaluation, and treatment of vocal system disorders in children and adults; current literature and clinical practice issues are addressed. A-F only. Pre: consent.

CSD 622 Adult Neurogenic Language and Cognitive-Communication Disorders (3)

Study of acquired adult language and cognitive communication disorders associated with stroke, traumatic brain injury, and dementia. Application of evidence-based procedures and strategies for assessment and intervention, review of current literature, and discussion of professional issues. A-F only. Pre: consent.

CSD 695 Research–Speech Pathology (1)

Required of all CSD graduate students following the non-thesis (Plan B) program and emphasizing speech-language pathology. Repeatable three times. Pre: 600 and consent.

CSD 696 Research–Audiology (3)

Required of all CSD graduate students following the non-thesis (Plan B) program and emphasizing audiology. Pre: 600 and consent.

CSD 699 (Alpha) Directed Study (V)

To allow student and faculty advisor to design research/study units outside existing academic structure in specialized area. Repeatable unlimited times. (B) language pathology; (C) audiology. Pre: 603 for (C).

CSD 700 Thesis Research (V)

Repeatable unlimited times. Pre: consent.

CSD 701 Amplification: Assessment and Applications (3)

Comprehensive study of amplification. Assessment, fitting, evaluation, electroacoustic evaluation, dispensing. Personal instruments and instructional-educational systems. Pre: 603 and consent.

CSD 702 Disorders of Fluency (3)

Contemporary developments and theoretical issues in diagnosis, evaluation, and treatment of disorders of fluency such as stuttering in both children and adults.

CSD 703 Electrophysiologic Audiometry (3)

Study of early, middle, and late auditory evoked potentials with emphasis on the auditory brainstem response. Pre: 603 or consent.

CSD 709 Dysphagia: Disorders of Swallowing (3)

Explores the dynamics of normal and disordered swallowing across the life span with emphasis on the adult population. CSD majors only. A-F only. Pre: 601 (with a minimum grade of B-). (Summer only)

CSD 710 (Alpha) Special Topics in Audiology and Speech-Language Pathology (3)

(B) study of contemporary developments in speech/language pathology; (C) study of contemporary developments in audiology. Repeatable for credit for different alphas unlimited times. Pre: consent.

CSD 716 Advanced Practicum in Speech Pathology II (6)

Clinical practice in diagnostic and therapeutic procedures with various types of speech and language problems in different clinical settings. Repeatable unlimited times, credit earned for 12 credits only

CSD 717 Advanced Practicum in Audiology II (2)

Clinical practice in administering tests and interpreting results; counseling individuals with impaired hearing; use of various rehabilitation techniques. Repeatable unlimited times. Pre: 603, 617, and consent.

CSD 721 Seminar in Audiology–Diagnostic Procedures (3)

Study of diagnostic procedures as reflected in current literature. Pre: 603 and consent.

CSD 723 Seminar in Audiology–Rehabilitative Procedures (3)

Procedures and philosophies presented in recent literature dealing with rehabilitative phases of audiology. Pre: 603 and consent.

CSD 724 Advanced Practicum in Speech Pathology III (V)

Clinical practice in diagnostic and therapeutic procedure with various types of speech and language problems in different clinical settings. Repeatable unlimited times, up to 18 credits.

CSD 725 Advanced Practicum in Audiology III (3)

Clinical practice in administering tests and interpreting results, counseling of individuals with impaired hearing; use of various rehabilitation techniques. Repeatable unlimited times. Pre: 603, 617, 717, and consent.

DRB 601 Fertilization and Early Development (2)

Lecture on the basics of vertebrate and invertebrate fertilization and early embryonic development. Open to all graduate students. (Fall only)

DRB 613 Seminar in Developmental and Reproductive Biology I (1)

Presentations of current research carried out by developmental and reproductive biology graduate program faculty.

DRB 614 Developmental and Reproductive Biology Scientific Investigations (3)

Discussion of current research in developmental and reproductive biology. A-F only.

DRB 650 Stem Cell Biology (3)

Seminar designed to teach graduate students and advanced undergraduate students about current topics relating to stem cell biology, as well as the application of stem cells to modern medicine. A-F only. Pre: BIOL 275 and PHYL 604, or consent. (Spring only)

DRB 666 Applied Developmental and Reproductive Biology (3)

Combined lecture-lab on current technologies and methods for mammalian reproduction and developmental biology. A-F only. Pre: 601 (or concurrent), 613/614 (or concurrent); or consent. (Spring only)

DRB 695 DRB Research Rotation (3)

Introductory laboratory research experience under the supervision of faculty. Repeatable two times. A-F only.

DRB 699 Directed Research (V)

Research experience in developmental and reproductive biology. Repeatable unlimited times.

DRB 700 Thesis Research (V)

Repeatable unlimited times.

DRB 800 Dissertation Research (V)

Repeatable unlimited times.

FMCH 531 7-Week Family Medicine Clerkship (10)

Ambulatory-based clerkship in Hawai‘i. Students learn history taking, physical exam skills, and management of family medicine patients. Emphasis on behavioral care, caring for the underserved, sports medicine, preventive care, common acute/chronic ambulatory problems. Pre: third year standing.

FMCH 532 Family Medicine and Community Health Longitudinal Clerkship (10)

5.5-month ambulatory clerkship. Students learn history taking, physical exam skills, and management of family medicine patients. Emphasis on behavioral care, caring for the underserved, sports medicine, preventive care, and common acute/chronic ambulatory problems. Repeatable one time. Co-requisite: third-year standing and concurrent registration in 532 courses.

FMCH 545 (Alpha) Electives in Family Medicine and Community Health (V)

Fourth-year elective in which medical students may do study of selected topics within the field of family medicine and community health: (B) primary care preceptorship; (C) topics in community health; (D) sub-internship in family medicine; (E) extramural elective in family medicine and community health-miscellaneous; (F) sports medicine preceptorship; (G) longitudinal underserved care preceptorship (6). MED majors only for (G). CR/NC only. Pre: 531 or 532. (Spring only for (G))

FMCH 599 Directed Reading/Research (V)

Repeatable unlimited times. Pre: consent.

GERI 541 Geriatric and Palliative Care (V)

This four-week rotation provides medical students with an overview of geriatric and palliative medicine in outpatient, inpatient, home care and nursing home settings. Students will receive one half-day per week of geriatric medicine didactic seminars and one half-day per week of palliative medicine didactic sessions. The clinical placements will be provided at several teaching sites including Kuakini Medical Center, Queen’s
Medical Center, the VA, several nursing homes on O‘ahu, Kaiser Permanente, Hospice Hawai‘i, St. Francis Hospice, Kapiolani Hospital, Straub Hospital, and the Pain & Symptom Management Program at Queen’s Medical Center.

GERI 542 Geriatric Medicine Research (V)

Medical students will have the opportunity to complete a research project in the field of epidemiology of aging, and present an abstract at a local meeting. Basic principles of epidemiology and statistics will be taught. Repeatable one time. CR/NC only. Pre: departmental approval.

GERI 545 Geriatric and Palliative Medicine Elective (V)

Four-week elective provides medical students with an overview of geriatric and palliative
medicine in outpatient, inpatient, home care and nursing home settings. Students receive one half-day per week of geriatric medicine didactic seminars and one half-day per week of palliative medicine didactic sessions. CR/NC only.

GERI 595 Medical Student Training in Aging Program (2)

Introduces medical students to clinical, research, and academic experiences in geriatrics, under the mentorship of faculty members. MD majors only. CR/NC only. Pre: DED 554 or consent. (Fall only)

MDED 527 Evidence-Based Medicine (1)

Critical appraisal track designed to improve the student’s ability to seek and evaluate new medical knowledge. MD majors only. CR/NC only. (Spring only)

MDED 528 Unit 8 Block Electives (V)

Through lectures, self-assessments and independent study, second-year medical students will consolidate their knowledge of the application of the biological sciences to patient care. CR/NC only. Pre: 557.

MDED 541 Clinical Skills Assessment (1)

Required comprehensive interdepartment multidisciplinary assessment program for fourth-year medical students. CR/NC only. Pre: FMCH, MED, OBGN, PED, PSTY, SURG 531 or 532.

MDED 545 (Alpha) Senior Interdisciplinary Electives (V)

Fourth-year elective in which students study selected interdisciplinary topics. CR/NC only. (B) medical education elective; (C) complementary and alternative medicine; (D) leadership in underserved care; (E) Junior PBL course director. MED majors only for (D). CR/NC only for (D) and (E). Pre: FMCH, MED, OBGN, PED, PSTY, SURG 531 or 532. (Spring only for (D) and (E))

MDED 551 MD 1 Health and Illness (5)

Introduction to concepts of health and disease through lectures, laboratories, and colloquia intended to broaden the learning from MD 1 health care problems in tutorials. MD majors only. CR/NC only. Pre: consent. Co-requisite: 551L. (Fall only)

MDED 551L MD 1 Health and Illness Tutorials (3)

Introductory series of problem-based learning tutorials for first-year medical students focusing on concepts of health and disease through MD 1 health care problems. MD majors only. CR/NC only. Co-requisite: 551. (Fall only)

MDED 552 MD 2 CV/Pulmonary (7)

Concepts focusing on cardiovascular and pulmonary systems through integrated basic science lectures, laboratories, and colloquia intended to broaden the learning from MD 2 health care problems in tutorials. CR/NC only. Pre: 551 and 551L. Co-requisite: 552L. (Fall only)

MDED 552L MD 2 CV/Pulmonary Tutorials (4)

Advanced series of problem-based learning tutorials for first-year medical students focusing on cardiovascular and pulmonary health care problems. CR/NC only. Pre: 551 and 551L. Co-requisite: 552. (Fall only)

MDED 553 MD 3 Renal/Hematology (7)

Concepts focusing on renal and hematologic systems through integrated basic science lectures, laboratories, and colloquia intended to broaden the learning from MD 3 health care problems in tutorials. CR/NC only. Pre: 552 and 552L. Co-requisites: 553L. (Spring only)

MDED 553L MD 3 Renal/Hematology Tutorials (4)

Advanced series of problem-based learning tutorials for first-year medical students focusing on renal and hematology health care problems. CR/NC only. Pre: 552 and 552L. Co-requisite: 553. (Spring only)

MDED 554 MD 4 GI/Endocrine (7)

Concepts focusing on gastrointestinal and endocrine systems through integrated basic science lectures, laboratories, and colloquia intended to broaden the learning from MD 4 health care problems in tutorials. CR/NC only. Pre: 553 and 553L. Co-requisite: 554L. (Spring only)

MDED 554L MD 4 GI/Endocrine Tutorials (4)

Advanced series of problem-based learning tutorials for first-year medical students focusing on gastrointestinal and endocrine health care problems. CR/NC only. Pre: 553 and 553L. Co-requisite: 554. (Spring only)

MDED 556 MD 6 Locomotor System, Nervous System and Behavioral Problems (8)

Concepts focusing on the locomotor/neurological systems and behavioral problems through integrated basic science lectures, laboratories, and colloquia intended to broaden the learning from MD 6 health care problems in tutorials. CR/NC only. Pre: 554 and 554L. Co-requisite: 556L. (Fall only)

MDED 556L MD 6 Locomotor System, Nervous System, and Behavioral Problems (6)

Advanced series of problem-based learning tutorials for second-year medical students focusing on neurological/ locomotor systems and behavioral health care problems. CR/NC only. Pre: 554 and 554L. Co-requisite: 556. (Fall only)

MDED 557 MD 7 The Life Cycle (7)

Concepts focusing on the life cycle through integrated basic science lectures, laboratories, and colloquia intended to broaden the learning from MD 7 health care problems in tutorials. CR/NC only. Pre: 556 and 556L. Co-requisite: 557L. (Spring only)

MDED 557L MD 7 The Life Cycle Tutorials (4)

Advanced series of problem-based learning tutorials for second-year medical students focusing on the life cycle health care problems. CR/NC only. Pre: 556 and 556L. Co-requisite: 557. (Spring only)

MDED 563 Third Year Colloquia (2)

A series of lecture-discussions intended to broaden the perspectives of the Unit VI experiences and healthcare problems. Repeatable one time. CR/NC only. Pre: 551 and 557.

MDED 564 (Alpha) Senior Seminars (1)

Review of topics and issues that will prepare senior students for the end of their undergraduate training and the start of their internship. (B) Week 1; (C) Week 2; (D) Week 3. CR/ NC only. (Fall only for B); (Spring only for C and D)

MDED 571 Introduction to Clinical Skills (2)

Introductory lectures and laboratories on history taking and physical exam skills. Repeatable one time. MD majors only. CR/NC only. Pre: consent. Co-requisite: 551. (Fall only)

MDED 572 Unit 2 Clinical Skills (2)

History and physical exam skills pertinent to the health care problems in Unit 2. MD majors only. CR/NC only. Pre: 571 or consent. (Fall only)

MDED 573 Unit 3 Clinical Skills (2)

History and physical exam skills pertinent to the health care problems in Unit 3. MD majors only. CR/NC only. Pre: 572 or consent. (Spring only)

MDED 574 Unit 4 Clinical Skills (2)

History and physical exam skills pertinent to the health care problems in Unit 4. MD majors only. CR/NC only. Pre: 573 or consent. (Spring only)

MDED 576 Unit 6 Clinical Skills (3)

History and physical exam skills pertinent to the health care problems in Unit 6. MD majors only. CR/NC only. Pre: 574 or consent. (Fall only)

MDED 577 Unit 7 Clinical Skills (2)

History and physical exam skills pertinent to the health care problems in Unit 7. MD majors only. CR/NC only. Pre: 576 or consent. (Spring only)

MDED 581 Unit 1 Community Health (2)

Field experience placing students in community settings to work with health care professionals as they provide services to patients. Repeatable two times. MD majors only. CR/NC only. Pre: consent. Co-requisites: 551 and 571. (Fall only)

MDED 582 Unit 2 Community Health (2)

Field experience placing students in community settings to work with health care professionals as they provide services to patients. Repeatable two times. MD majors only. CR/NC only. Pre: 581 or consent. (Fall only)

MDED 583 Unit 3 Community Health (2)

Field experience placing student in community settings to work with health care professionals as they provide services to patients. MD majors only. CR/NC only. Pre: 582 or consent. (Spring only)

MDED 584 Unit 4 Community Health (2)

Field experience placing student in community settings to work with health care professionals as they provide services to patients. MD majors only. CR/NC only. Pre: 583 or consent. (Spring only)

MDED 590 (Alpha) Preclinical Electives (V)

Elective for first and second year medical students. (B) projects in medical education; (C) healer’s art; (D) introduction to student research; (E) health and wellness; (F) quality improvement; (G) introduction to ultrasound. Repeatable one time, up to two credits. MD majors only for (G). CR/NC only. Pre: 551.

MDED 595 (Alpha) Topics in Medical Education (V)

Summer selectives in medical education for second-year medical students. (B) rural health preceptorship; (C) health issues of the Pacific Basin; (D) projects in medical education; (E) manikin simulations; (F) learning resources; (G) cardiovascular case maps; (H) pulmonary case maps; (I) clinical skills preceptors; (J) global health perspectives. Repeatable up to four credits. MD majors only. CR/NC only. Pre: 554. (Fall only)

MDED 599 Research in Medical Education (V)

An elective for medical students to work on research projects related to improving medical education, student wellness, and community health under the direction of a faculty member in the Office of Medical Education. Repeatable nine times, up to six credits.

MDHX 699 Directed Research (V)

Repeatable unlimited times.

MED 531 Internal Medicine Clerkship (16)

Required for third-year medical students, 11-week duration. Ambulatory care and hospital-based experience. Pre: third year medical student standing.

MED 532 Internal Medicine Longitudinal Clerkship (8)

Six-month long clerkship in ambulatory setting, and six-week hospital-based experience. Repeatable one time. Pre: third-year standing and concurrent registration in 532 courses. Six-month long clerkship in ambulatory setting, and six-week hospital-based experience. Repeatable one time. Pre: third-year standing and concurrent registration in 532 courses.

MED 541 Advanced Medicine Clerkship (6)

Required 4 weeks duration for fourth-year medical students. Advanced experiences in ambulatory and hospital-based medical care. Proficiency in this course may be established by examination. CR/NC only. Pre: fourth-year standing and completion of 531, or consent.

MED 545 (Alpha) Electives in Medicine (V)

Fourth-year electives in which students study selected topics within field of medicine. (B) allergy/ immunology; (C) cardiology; (D) medicine elective in Asia; (E) dermatology; (F) endocrinology; (G) gastroenterology; (H) general internal medicine: ambulatory care; (I) general internal medicine: inpatient; (K) hematology; (M) nephrology; (N) neurology; (O) nuclear medicine; (P) oncology; (Q) pulmonary diseases; (R) research in medicine; (S) rehabilitation medicine; (T) rheumatology; (W) internal medicine sub-internship. CR/NC only. Pre: 531 or 532 for (C), (E), (F), (G), (H), (K), (M), (N), (O), (Q), (R), (S), and (T); 541 for (D) and (W).

MED 546 (Alpha) Electives in Medicine (V)

Fourthyear electives in which students study selected topics within field of medicine. (B) extramural electives in medicine (miscellaneous); (C) internal medicine seminar; (D) infectious disease; (E) internal medicine sub-internship; (F) research in bioethics; (G) neurology critical care; (H) medical informatics; (O) obesity medicine. Repeatable one time for (C)–(E); not repeatable for (F); repeatable two times for (B), (C) and (H); repeatable three times for (G). CR/NC only. Pre: 531 or 532 for (B), (C), and (O); 541 for (E) and (H).

MED 599 Directed Research (V)

Pre: consent.

MEDT 151 Introduction to Medical Technology (2)

Designed to acquaint students to the field of medical technology (clinical laboratory science). Repeatable one time.

MEDT 251 Introduction to Medical Technology II (2)

Basic principles and lab skills in medical technology (medical lab science). Required for second bachelor’s degree students (not MLT credentialed) wishing to major in medical technology. Second bachelor’s degree students only. A-F only. Pre: 151, CHEM 161/CHEM 161L, BIOL 171/BIOL 171L (or concurrent)

MEDT 301 The Clinical Laboratory (3)

(2 Lec, 1 3-hr Lab) Theory and clinical application of medical laboratory methods and healthcare professional relationships. MEDT majors only. Repeatable one time. Pre: consent.

MEDT 302 The Clinical Laboratory II (3)

Theory and clinical application of medical technology methods and healthcare professional relationships. Companion course to MEDT 301; and required, for second bachelor’s degree students who were admitted to MEDT major. MEDT majors only. Second Bachelor’s degree standing or higher. A-F only. Pre: 251 or consent.

MEDT 331 Clinical Lab Management (3)

Student will become familiar with fundamental administration of a clinical laboratory to include technical, personnel, and financial management areas. Repeatable one time. MEDT majors only. CR/NC only. Pre: consent.

MEDT 431 Clinical Parasitology (2)

(1 Lec, 1 3-hr Lab) Modern diagnostic practices in parasitology. Repeatable one time. Pre: MICR 351 or consent.

MEDT 451 Hematology (1)

(1 3-hr Lab) Fundamental study of blood in normal and pathological states: formation, development, and classification of blood cells. MEDT majors only. Pre: major or consent.

MEDT 451L Hematology Lab (2)

(1 Lec, 1 3-hr Lab) Laboratory to accompany MEDT 451. MEDT majors only. Pre: major or consent. Co-requisite: 451.

MEDT 464 Immunohematology (3)

(2 Lec, 1 3-hr Lab) Antigen-antibody relationships in human blood, study of blood groups, clinical problems in transfusion. Repeatable one time. MEDT majors only. Pre: MICR 461 or consent. (Spring only)

MEDT 471 Clinical Biochemistry I (4)

Biochemical processes in human health and disease states. Repeatable one time. MEDT majors only. Pre: CHEM 273 or consent. (Spring only)

MEDT 472 Clinical Biochemistry II (4)

Continuation of 471. Repeatable one time. MEDT majors only. Pre: 471 or consent. (Once a year)

MEDT 477 Clinical Lab Methods and Analyses I (3)

(2 Lec, 1 3-hr Lab) Lab experiments illustrating fundamental principles and methods of clinical laboratory analyses. Repeatable one time. MEDT majors only. A-F only. Pre: 471.

MEDT 478 Clinical Lab Methods and Analyses II (3)

(2 Lec, 1 3-hr Lab) Continuation of 477. Repeatable one time. MEDT majors only. A-F only. Pre: 477.

MEDT 481 Professional Issues in Medical Lab Science (1)

Discussions about various professional issues through oral presentations and critiquing of peer presentations. Repeatable one time. MEDT majors only. CR/NC only. Pre: 451L.

MEDT 495 Special Topics in Medical Technology (V)

Acquaints student with role of the medical technologist and overlap of major sciences in clinical situations to help student develop qualities unique to med technology. Repeatable one time. MEDT majors only. CR/NC only. Pre: consent.

MEDT 499 Directed Reading and Research (V)

Repeatable one time.

MEDT 531 Advanced Lab Management Concepts and Contemporary Issues (1)

Concepts in clinical laboratory management and discussion of contemporary issues for graduates and practicing clinical laboratory scientists. Repeatable one time. Pre: 331 or consent. (Summer session only)

MEDT 551 Advanced Clinical Laboratory Hematology and Hemostasis (1)

Advanced-level study of hematology and hemostasis through clinical laboratory cases. Repeatable one time. Pre: 451 or consent. (Summer only)

MEDT 581 Clinical Microbiology Preceptorship (5)

Clinical training for students with bachelor’s degree in microbiology to be able to qualify as clinical microbiologists in a healthcare setting. Includes specimen procurement, processing, detection and identification, susceptibility testing, and other diagnostic technology. CR/NC only. Pre: departmental consent. (Fall only)

MEDT 591 Clinical Training in Medical Technology (28)

Application of theory and simulated laboratory experiences in immuno-hematology, clinical chemistry, microbiology, parasitology, hematology, coagulation, urinalysis, immunology, to meet stated career entry-level competencies. Repeatable one time. CR/NC only. Pre: BS in MEDT.

MEDT 690 Seminar in Medical Technology (1)

Analysis of research and recent literature pertaining to various aspects of medical technology. Repeatable one time. Pre: consent.

NHH 450 Applied Health Disparities Research (V)

Instruction on social determinants of health, issues of health equity, and how these issues can be addressed through research. Discussions and activities promote a greater understanding of health disparities research. Repeatable unlimited times. Pre: consent.

NHH 499 Directed Reading/Research (V)

Individual reading and/or research. Repeatable unlimited times. Junior standing or higher. Pre: consent.

NHH 501 Humanities in Medicine I (2)

Introduction to medical science stressing key historical figures and significant events to exemplify the development of scientific methods. Special emphasis on writing skills, health team concept, and culture and contributions of the Pacific. Repeatable one time. CR/NC only. Pre: admission to Imi Ho‘ola PostBaccalaureate Program.

NHH 502 Humanities in Medicine II (2)

Continuation of 501. Repeatable one time. CR/NC only. Pre: 501.

NHH 503 Medical Biology I (11)

(2 Lec, 2 Tutorial, 1 3-hr Lab) Foundation in medical sciences, including anatomy, physiology, microbiology, pathology, and pharmacology (focus on respiratory, cardiovascular, and urinary systems); develop critical thinking and problem-solving skills. Includes lectures, problembased tutorials, and histology and gross anatomy labs. CR/NC only. Pre: admission to Imi Ho‘ola PostBaccalaureate Program.

NHH 504 Medical Biology II (11)

(2 Lec, 2 Tutorial, 1 3-hr Lab) Continuation of 503. CR/NC only. Pre: 503.

NHH 505 Medical Biochemistry I (6)

Provide background knowledge of chemistry, biochemistry, and molecular biology with emphasis in principles of biochemical processes as well as clinical correlations to medical conditions; develop critical thinking, standardized test taking skills, and problem-solving skills. CR/NC only. Pre: admission to Imi Ho‘ola Post-Baccalaureate Program.

NHH 506 Medical Biochemistry II (6)

Continuation of 505. CR/NC only. Pre: 505.

NHH 513 Native Hawaiian Health and Traditional Healing (1)

Introduction to Native Hawaiian health issues and traditional healing practices. MD majors only. CR/NC only. Pre: MDED 551 or consent.

NHH 545 Native Hawaiian Health Care (V)

Clinical experience in the Native Hawaiian Health Care System and community health care centers, incorporating both western and traditional Hawaiian medicine. Open to fourth year medical students interested in Native Hawaiian Health Care. CR/NC only. Pre: MED 531 or MED 532.

NHH 575 Seminar in Issues of Social Justice in Health (1)

Social justice provides an analytical and prescriptive framework to understand health inequities; understand connections between social forces and health outcomes, and the role of the individual student in improving social justice in the health system. Graduate standing only. CR/NC only. Pre: MDED 551. (Spring only)

NHH 595 Clinical Skills Preceptorship in the Lau Ola Clinic of the Department of Native Hawaiian Health (V)

Provides a focused experience in clinical medicine with opportunities to practice the history and physical examination in Lau Ola, the clinical setting of the Department of Native Hawaiian Health. Repeatable one time. MD majors only. CR/NC only. Pre: MDED 574 or consent. (Fall only)

NHH 650 Advanced Applied Health Disparities Research (V)

Instruction on social determinants of health, issues of health equity, and how these issues can be addressed through research. Discussions and activities promote a greater understanding of health disparities research. Repeatable two times, or up to 27 credits. Pre: consent.

NHH 699 Directed Reading/Research (V)

Individual reading and/or research. Repeatable unlimited times. Graduate standing only. Pre: consent.

OBGN 531 7-Week OB/GYN Clerkship (10)

7-week basic obstetric/gynecology clerkship. Repeatable one time. Pre: third year standing.

OBGN 532 Obstetrics and Gynecology Longitudinal Clerkship (5)

Year-long clerkship in outpatient setting, covering assessment, diagnosis, treatment, and/or management of common gynecologic problems and normal and complicated pregnancies. Emphasis on prevention and health maintenance. Repeatable two times. Pre: third-year standing, and concurrent registration in 532 courses. Co-requisite: FMCH, MED, PED, PSTY, and SURG 632.

OBGN 545 (Alpha) Electives in OB/GYN (V)

Opportunities for advanced study of selected topics. (B) labor and delivery; (C) outpatient clinic at Queen’s; (D) Sub-internship in family planning; (E) high-risk OB; (F) endocrinology; (G) oncology; (H) topics with individual preceptor; (I) extramural electives; (J) urogynecology and pelvic reconstructive surgery. Repeatable twice for each alpha. CR/NC only. Pre: 531 or 532.

OBGN 599 Directed Reading/Research (3)

Pre: consent.

PATH 470 Immunopathology Seminar (1)

Autoimmune diseases and transplantation immunity. Pre: consent.

PATH 499 Directed Research (V)

Pathology of aging, nutrition, alcoholism, and immunology. Open to selected undergraduate students. Repeatable unlimited times. Pre: consent.

PATH 512 Unit II Concurrent Elective (1)

Elective course for first-year medical students. CR/NC only. Pre: BIOM 551 and consent.

PATH 515 Unit V Concurrent Elective (1)

Elective course for second-year medical students. CR/NC only. Pre: BIOM 551 and consent.

PATH 525 Unit V Block Elective (V)

Required elective for second-year medical students, objectives to be determined by contract. One option is a review of USMLE Part I. CR/NC only. Pre: BIOM 551.

PATH 541 Pathology Practicum (V)

Required autopsy experience involving dissection and microscopic examination of tissues and detailed evaluation of disease process. CR/NC only. Pre: third-or fourth-year standing.

PATH 545 (Alpha) Unit VII Electives in Pathology (V)

Individualized instruction in laboratory medicine for the practicing physician, clinical and anatomic pathology: (B) advanced topics in clinical immunology; (C) anatomic pathology; (D) clinical pathology; (E) pathologic aspects of aging, nutrition, and/or alcoholism; (F) extramural elective in pathology. Repeatable four times. CR/NC only. Pre: BIOM 555.

PATH 595 Introduction to Pathology and Laboratory Medicine (1)

Provides an introduction to the practice of pathology and laboratory medicine and the role pathologists and the laboratory play in the diagnosis and management of disease. MD students only. CR/NC only. Pre: MDED 554 or consent. (Fall only)

PATH 599 Electives in Pathology (V)

Individualized instruction in clinical and/or anatomic pathology. Third-year elective. Repeatable unlimited times. Pre: consent.

PED 501 Pediatric Seminars (1)

Interactive weekly lecture/seminar designed to teach topics in pediatrics and supplemented by small group 2-hour encounters with faculty clinicians in pediatric emergency medicine, inpatient pediatric, and enonatology to gain exposure in pediatric hospital care. Repeatable one time. Medical students only. CR/NC only. Pre: MDED 551.

PED 506 Introduction to Research Methodology, Biostatistics, and Epidemiology (1)

Interactive seminar series to cover the following topics: data types, descriptive statistics, inferential statistics, selecting a statistical test, data distributions, measures of data spread, statistical test assumptions, standard deviation vs. standard error, etc. Repeatable one time. Medical students only. CR/NC only. Pre: MDED 551.

PED 531 7-Week Pediatric Clerkship (10)

7-week basic pediatric clerkship. Repeatable one time. Pre: third-year standing.

PED 532 Pediatrics Longitudinal Clerkship (5)

Year-long clerkship in ambulatory setting, covering evaluation, diagnosis, and treatment of childhood diseases. Emphasis on primary prevention, normal growth and development of the neonate to adolescent, and arrangement of pediatric care, including outpatient, inpatient, and emergency room experiences. Repeatable two times. Pre: third-year standing and concurrent registration in 532 courses. Co-requisite: MED, OBGN, PED, PSTY, and SURG 532.

PED 545 (Alpha) Electives in Pediatrics (V)

Fourth-year elective in pediatric sub-specialty areas in which medical students may receive clinical experiences and an in-depth study of selected sub-specialty areas within the field of pediatrics. (B) adolescent medicine; (C) ambulatory pediatric care; (E) clinical genetics; (F) Sub-Internship in neonatology; (G) pediatric cardiology; (H) Sub-Internship in pediatric emergency medicine; (I) Sub-Internship in pediatric hematology/ oncology; (J) Sub-Internship in infectious diseases; (K) Sub-Internship in pediatrics–general ward in pediatrics; (M) extramural electives in pediatrics; (N) pediatric rheumatology; (P) developmental behavioral pediatrics; (Q) pediatric international preceptorship (3 cr.); (R) Sub-Internship in pediatric critical care;. (S) pediatric radiology; (T) pediatric ultrasound; (U) pediatric nephrology; (V) pediatric sports medicine. CR/NC only. Repeatable two times per alpha, up to 36 credits; not repeatable for (Q). Pre: 531 or 532.

PED 599 Directed Reading/Research (V)

Repeatable unlimited times. CR/NC only. Pre: consent.

PHRM 201 Introduction to General Pharmacology (2)

Drugs discussed with emphasis on sites and mechanism of action, toxicity, fate, and uses of major therapeutic agents. Pre: mammalian physiology and dental hygiene major.

PHRM 203 General Pharmacology (3)

Similar to 201 but wider in scope of drugs discussed. Intended for undergraduates in the health sciences and related fields. Pre: mammalian physiology.

PHRM 499 Directed Reading and Research (V)

Directed reading and research in experimental pharmacology. Repeatable unlimited times. Pre: consent.

PHRM 590 Selected Topics in Pharmacology (V)

Elective for medical students in Pharmacology. Repeatable up to 12 credits. CR/NC only. Pre: MDED 551.

PHRM 595 Principles of Pharmacology (1)

Pharmacology elective course for medical students. MD students only. CR/NC only. Pre: MDED 554 or consent. (Fall only)

PHRM 599 Research in Pharmacology (V)

Pharmacology research elective for medical students. MD majors only. CR/NC only. Pre: MDED 551 or consent.

PHRM 601 General Pharmacology (3)

Pharmacodynamics, receptor theory, modeling, clinical trials and the FDA will be covered. Concepts in ADME/T and clinical research are also considered. Pre: consent.

PHRM 602 Systemic Pharmacology (9)

Provides instruction at an organ systems/functional level covering major organ and functional systems of the human body. Concepts in pharmacological research at the animal, organ system and whole human level will also be considered. Repeatable one time. Pre: consent.

PHRM 640 Neuropharmacology (2)

Physiology and pharmacology of central and peripheral nervous systems, focusing on synaptic chemistry and signaling. A-F only. Pre: CMB 606, or consent from the course director. (Cross-listed as CMB 640)

PHRM 699 Directed Research (V)

Repeatable unlimited times.

PHRM 700 Thesis Research (V)

Repeatable unlimited times.

PHRM 800 Dissertation Research (V)

Repeatable unlimited times.

PHYL 103 Human Physiology and Anatomy (5)

Introduction to human physiology and anatomy designed to serve the needs of dental hygiene students and others interested in pursuing health-related careers.

PHYL 103L Physiology and Anatomy Lab (1)

Laboratory to complement 103. Co-requisite: 103.

PHYL 141 Human Anatomy and Physiology (3)

Anatomy, histology, physiology, biochemistry, genetics of human organ systems presented in integrated anatomy-physiology format. Priority to students in nursing. Pre: high school chemistry.

PHYL 141L Human Anatomy and Physiology Lab (1)

Anatomy, histology, physiology, biochemistry, genetics of human organ systems presented in integrated anatomy-physiology format. Priority to students in nursing. Pre: 141 (or concurrent) or consent.

PHYL 142 Human Anatomy and Physiology (3)

Continuation of 141. Pre: should have an understanding of basic physiology concepts as presented in 141 or equivalent.

PHYL 142L Human Anatomy and Physiology Lab (1)

Anatomy, histology, physiology, biochemistry, genetics of human organ systems presented in integrated anatomy-physiology format. Priority to students in nursing. Pre: 142 (or concurrent) or consent.

PHYL 301 Advanced Anatomy and Physiology (4)

Integrated presentation of human anatomy and physiology. An optional laboratory (PHYL 301L) is available separately. Pre: BIOL 171 and BIOL 172, or any PHYL course; and CHEM 161 (or higher) or any BIOC course; or consent.

PHYL 301L Human Anatomy and Physiology Lab (1)

Laboratory study of human anatomy and physiology by means of models, histology slides, experiments, and demonstrations. Co-requisite: 301 or consent.

PHYL 302 Advanced Anatomy and Physiology (4)

Continuation of 301. Pre: 301/301L or consent.

PHYL 302L Human Anatomy and Physiology Lab (1)

Continuation of 301L. Pre: 301/301L, or consent. Co-requisite: 302.

PHYL 401 Human Physiology: Organ Systems (4)

Basic function of the major organ systems in man. Covers cardiovascular, respiratory, renal, acid-base, and gastrointestinal physiology. Pre: 302 or equivalent with consent.

PHYL 402 Human Physiology: Integrative Systems (4)

Senior-level course in integrative systems (central nervous system and endocrinology). Complements 401. Pre: 401 and either BIOC 341 or CHEM 152, or consent.

PHYL 405 Applied Muscle Physiology (3)

Science and technology of strength training. Anatomy, kinesiology, physics, and physiology applied to development of muscular strength and mass. Repeatable one time. A-F only. Pre: 302; or consent.

PHYL 499 Directed Reading or Research (V)

Students will learn fundamental concepts and multiple techniques in molecular biology, physiology, and histology for cardiovascular research through the projects in the lab. Repeatable unlimited times, but credit earned to two credits only. Junior or senior standing only. CR/NC only.

PSTY 499 Directed Reading/Research (V)

Individualized directed readings and/or research in mental health and psychiatry under the supervision of an instructor. Open to non-majors. Repeatable up to four times. A-F only. Pre: consent.

PSTY 531 7-Week Psychiatry Clerkship (10)

7-week basic psychiatry clerkship. Repeatable one time. Pre: third-year standing.

PSTY 532 Psychiatry Longitudinal Clerkship (5)

Year-long clerkship in ambulatory setting, including knowledge, skills, attitudes for assessment, diagnosis, and management of psychiatric problems in medical practice, inpatient, and emergency room settings. Emphasis on development and application of psychosocial cultural formulations in all areas of psychiatric and medical practice. Repeatable two times. MD majors only. Pre: third-year standing and concurrent registration in 532 courses. Co-requisites: FMCH, MED, OBGN, PEDS, SURG 532 and SURG 535.

PSTY 545 (Alpha) Electives in Psychiatry (V)

Senior medical student elective providing advanced instruction on the theory and methods of mental health research as well as supervised participation in an assigned research project in the Department of Psychiatry. (B) adult inpatient PSTY; (C) child PSTY; (D) forensic PSTY; (E) journal editing; (F) community mental health; (G) PSTY aspects of OBGN, PED, MED, SURG; (H) sub-internship in adult PSTY; (I) substance abuse; (J) PSTY aspects of rehab medicine; (K) PSTY aspects of SURG; (M) PSTY consult liaison; (N) post-traumatic stress disorder; (O) extramural elective in PSTY; (Q) geriatric PSTY; (R) rural child PSTY; (S) public and rural PSTY; (T) mental health research. CR/NC only. Pre: 531 or 532, and fourth-year standing.

PSTY 595 Philosophy & Human Suffering (1)

To see how various philosophies and religions have tackled the question, “why is there suffering in the world?” Read short excerpts from “classic” texts and discuss in a welcoming atmosphere and draw own conclusions. Medical students only. CR/NC only. (Fall only)

PSTY 599 Directed Reading/Research (V)

Pre: consent.

QHS 499 Directed Reading/Research (V)

Directed reading/research in quantitative health sciences. Students will work closely with a QHS faculty member or mentor who will guide them through quantitative methodologies and/or the process of conducting a research study. Repeatable three times or up to 12 credits. A-F only.

QHS 601 Biomedical Statistics (3)

Fundamental biomedical statistics concepts and tools will be introduced, as well as their applications to biomedical data. Students will perform hands-on analysis using statistical software and learn to interpret and present the results. A-F only. (Fall only) (Cross-listed as TRMD 655)

QHS 602 Biomedical Statistics II (3)

Advanced biomedical statistics principles and tools as well as their applications will be introduced. Topics include: model selection, hierarchical model, repeated measurements, proportional hazard model, classification methods, structural equation modeling and multivariate analysis. A-F only. Pre: 601 (with a minimum grade of B) or consent.

QHS 610 Bioinformatics I (3)

Fundamental concepts in bioinformatics with a strong emphasis on hands-on training. Covers topics such as molecular biology, sequence alignment, biological databases, phylogeny, and genomics, including microarray and RNA-seq data analysis. A-F only. (Fall only)

QHS 611 Bioinformatics II (3)

Focus on bioinformatics approaches for functional genomics related to DNA, RNA, and protein. It will provide of virus, bacteria, and human genome and bioinformatics approaches to human disease. A-F only. Pre: 610 (or equivalent) (with a minimum grade of B) or consent.

QHS 620 Introduction to Clinical Trials (2)

Introduction to clinical trials. Topics include history, definitions/terminology, adverse events, FDA and government regulatory agencies, ethics; monitoring committees, recruitment, introduction to protocol development, basis designs. A-F only.

QHS 621 Design and Analysis of Clinical Trials (2)

Covers basic and advanced statistical methods utilized in clinical trials design, conduct, and data analysis. Topics cover statistician’s role in drug development and DSMB, statistical theory in phases I-IV clinical trial designs and analysis. A-F only. Pre: 601 (or equivalent) or consent.

QHS 650 Secondary Data Analysis (2)

Will allow students who are new to using secondary data to become comfortable with accessing the data, forming hypotheses, and designing study proposals. Will introduce examples with basic and advanced techniques. A-F only.

QHS 651 Secondary Data Analysis Practicum (2)

Introduces students to issues in working with complex data sets and adds the hands-on experience needed to conduct individual research using secondary databases. A-F only. Pre: (601 (or equivalent) and 650) with a minimum grade of B, which can be taken concurrently.

QHS 670 Special Topics in Quantitative Health Sciences (V)

Special topics in quantitative health sciences. Reflects special research interest of QHS faculty or guest lecturers. Repeatable unlimited times. A-F only.

QHS 675 Biostatistical Consulting (2)

Investigate the roles and responsibilities of the biostatistician as both consultant and collaborator with biomedical researchers, guide students in enhancing problem-solving and communication skills, and provide opportunity to observe real-life biostatistical consultations. A-F only. Pre: 601 and 602 (or equivalent), or consent.

QHS 676 Biostatistical Consulting Practicum (V)

Under the supervision of biostatistics faculty members, students will have the opportunity to provide statistical consultations to biomedical researchers and gain hands-on experience conducting biostatistical analysis in solving real-life analytic problems. Repeatable two times, up to six credits. A-F only. Pre: 675 (or concurrent.)

QHS 699 Directed Research (V)

Directed research in quantitative health sciences. Students will work closely with a QHS faculty member or mentor who will guide them through the process of conducting a research study. Repeatable two time, up to nine credits. A-F only.

REPR 499 Directed Reading/Research (V)

Repeatable unlimited times.

REPR 611 Seminar in Biomedical Sciences (1)

Presentation and discussion of current research topics in biomedical sciences. Repeatable nine times. Pre: consent. (Cross-listed as CMB 611)

REPR 699 Directed Research (V)

Repeatable unlimited times.

REPR 700 Thesis Research (V)

Repeatable unlimited times. Pre: admission to candidacy (master’s program).

REPR 705 Special Topics in Reproductive Biology (V)

In-depth discussion of selected areas of reproductive biology, with special emphasis on recent research results and methodologies. May be retaken for credit. Pre: consent.

REPR 800 Dissertation Research (V)

Repeatable unlimited times. Pre: admission to candidacy (PhD program).

SURG 531 Surgery Clerkship (10)

A clinically based, introductory course in general surgery and elected subspecialties. Repeatable one time. Pre: third-year standing.

SURG 532 Surgery Longitudinal Clerkship (5)

A clinically based, year-long, introductory in general surgery and selected subspecialties. Outpatient-conducted one day per week for six months in a community-based, ambulatory care facility. Inpatient-conducted for four weeks in an acute-care hospital facility. Repeatable one time.

SURG 541 Emergency Medical Care (6)

Clinical experiences in management of medical, surgical, and psychiatric problems requiring urgent care. Pre: 531 and fourth-year standing.

SURG 545 (Alpha) Electives in Surgery (V)

Advanced clinical experience in: (B) urology; (C) ophthalmology; (D) otolaryngology; (E) plastic surgery; (F) neurosurgery; (G) orthopaedics; (H) anesthesia; (I) surgical intensive care; (J)Sub-I– general surgery; (K) Sub-I–pediatric surgery; (M) diagnostic radiology; (N) radiation oncology; (O) EM Sub-I; (P) extramural elec in surg; (Q) Sub-I– cardiovascular; (R) surgical research; (S) surgical anatomy; (T) preceptorship in Asia; (U) biomedical technology design; (X) transplant surgery; (Y) bedside ultrasounds; (Z) laparoscopic skills. Repeatable one time for all except (U), (X), (Y), and (Z); repeatable two times for (U) and (X). Medical students only for (U), (X), (Y), and (Z). CR/NC only. Pre: 531 or 532 for all except (M), (U), and (Y); and consent for (R) and (S); admission into JABSOM for (U) and (Y).

TRMD 431 Principles of Medical Parasitology (2)

Epidemiology, pathogenesis, immunobiology and diagnostic aspects of human parasitic infections; principles of host-pathogen interactions; public health aspects of parasitic infections. Repeatable one time. A-F only. Pre: MICR 351 with a grade of B or higher or equivalent. (Spring only)

TRMD 440 International Training in Biosciences Research (3)

Combines weekly lectures by faculty for discussion of the 9 Steps of Research and completion of training courses for working with human subjects, including research ethics, laboratory safety, blood-borne pathogens, and principles of health disparity. MHIRT cohort only. A-F only. (Summer only)

TRMD 441 International Health Disparities (2)

Overview of biosciences research related to health and health disparities in a global setting as well as in Hawai‘i. Workshop topics include health research, Native Hawaiian health, global health, and cultural competency. MHIRT cohort only. A-F only. (Summer only)

TRMD 442 Research Abroad (5)

Hands-on research experience at assigned international sites. Students learn research and analytical skills in the field and laboratory setting, and present data to peers and faculty upon completion of the training. MHIRT cohort only. A-F only. (Summer only)

TRMD 499 Reading and Research (V)

Directed reading and research in laboratory; diagnostic aspects of bacterial, parasitic, and viral infections. Repeatable unlimited times. Pre: consent.

TRMD 545 Topics in Tropical Medicine (V)

Elective for fourth-year medical students for advanced study of selected topics within the field of tropical medicine and medical microbiology. Pre: fourth-year standing or MD degree.

TRMD 590 Selected Topics in Tropical Medicine and Infectious Diseases (V)

Elective for medical students in Tropical Medicine and Infectious Diseases. Repeatable six times, up to 12 credits. Medical students only. CR/NC only. Pre: consent.

TRMD 595 (Alpha) Selected Topics in Infectious Diseases (V)

Elective for medical students; (B) infectious diseases; (C) parasitology; (D) epidemiology; (E) immunology. MD majors only. CR/NC only. Pre: MDED 554 or consent. (Fall only)

TRMD 599 (Alpha) Selected Research Topics in Infectious Diseases (V)

Research elective for medical students; (B) infectious diseases; (C) parasitology; (D) epidemiology; (E) immunology. MD majors only. CR/NC only. Pre: MDED 554 or consent. (Fall only)

TRMD 601 Tropical Medicine Journal Club (1)

Students gain experience in the presentation and discussion of topics of current interest in the fields of tropical medicine and infectious diseases. Repeatable unlimited times. Graduate students only.

TRMD 602 Laboratory Methods in Tropical Medicine (2)

Microbiologic methods and techniques for identification of pathogenic viruses, bacterial, and parasitic organisms including specimen handling, culturing, and laboratory safety. Repeatable one time. Graduate standing only. A-F only. (Fall only)

TRMD 603 Infectious Disease Microbiology I: Medical Parasitology (3)

Epidemiology, pathogenesis, immunobiology and diagnostic aspects of human parasitic infections; principles of host-pathogen interactions; public health aspects of parasitic infections. Repeatable one time. A-F only. Pre: MICR 351 or equivalent. (Fall only)

TRMD 604 Concepts in Immunology and Immunopathogenesis (2)

Immunological concepts relating to infectious diseases and host pathogen interactions. Repeatable one time. A-F only. Pre: MICR 461 (or equivalent) or consent. (Cross-listed as PH 665)

TRMD 605 Infectious Disease Micro II (3)

Will cover different families of animal viruses of importance to human diseases. The genome, structure, replication, as well as host immune responses, epidemiology, clinical features, and animal models will be presented. Repeatable one time. A-F only. Pre: 604 and MICR 351, or consent. (Cross-listed as PH 667)

TRMD 606 Tropical Medicine Laboratory Rotations (V)

Practical experience in use of equipment and procedures in infectious disease and immunology research; introduction to research in tropical medicine. Repeatable unlimited times. Pre: 604 (or concurrent), or consent.

TRMD 607 Neurovirology (2)

Seminar on neuroinvasive viruses giving basics of viruses causing nervous system diseases and discussing recent advances in the research field of neurovirology. Pre: MICR 351 or equivalent; or consent. (Fall only)

TRMD 608 Infectious Disease Microbiology III (3)

Basic structure, physiology, epidemiology, and genetics of pathogenic bacteria as well as the host response to these organisms. Correlation of these characteristics to disease pathogenesis in humans and animal models. A-F only. Pre: 604 or consent. (Spring only)

TRMD 609 Advances In Medical Immunology (3)

Presentations/discussions of current literature concerning recent advances in immunology relevant to disease and to disease processes. Pre: consent. (Alt. years: spring)

TRMD 610 Infection and Immunity (3)

Combined lecture/discussion of interactions of pathogens with the innate and acquired immune systems. Topics will include the role of novel receptors in pathogen detection, inflammation in disease pathogenesis, pathogen immune evasion, and neuroimmunology. Repeatable two times. A-F only. Pre: 604, MICR 461, or consent. (Alt. years: fall)

TRMD 650 Ecological Epidemiology (2)

Applications of population biology, pathogen/host life history, and population genetics to infectious disease epidemiology, including micro- and macroparasites, and implications to disease control and prevention of strategies. A-F only. Pre: consent. (Alt. years: spring) (Cross-listed as PH 650)

TRMD 651 Vaccinology (2)

History/evolution of vaccines, current and next generation vaccines, vaccine immunology, adjuvants, vaccine strategies, vaccines for viral, bacterial, and parasitic diseases, vaccine-proof-of-concept and downstream developmental studies; vaccine safety production processes. Repeatable one time. Graduate students only. A-F only. Pre: (604 and 605) with a minimum grade of B. (Spring only

TRMD 652 Advanced Genetics and Evolution of Infectious Diseases (2)

An evolutionary perspective to examine the interactive responses between infectious agents and the immune system. Topics will include natural selection, life history evolution, population genetics of pathogens and hosts, and anti-microbial resistance. A-F only. Pre: 604 (or concurrent) and 605 (or concurrent), or consent. (Alt. years: spring)

TRMD 653 Bioinformatics and Molecular Evolution (3)

Combined lecture/computer lab on bioinformatic tools used in genomics, including sequence assembly, search algorithms, alignment, phylogenetics, and molecular evolution/epidemiology. Focus will be on infectious disease examples. Repeatable one time, but credit earned one time only. Open to nonmajors. A-F only. Pre: 604 (or concurrent) and 605 (or concurrent) or consent.

TRMD 654 Advances in HIV/AIDS (2)

History of HIV, basic biology and virology, epidemiology, HIV pathogenesis and immunology, clinical features, and co-morbidities. Treatment and prevention of HIV/ AIDS, including research methods, statistics, cultural competence, genetics, pathophysiology, drug and vaccine development. Repeatable unlimited times. A-F only. Pre: 604 and 605, or consent. (Fall only)

TRMD 655 Biomedical Statistics (3)

Fundamental biomedical statistics concepts and tools will be introduced, as well as their applications to biomedical data. Students will perform hands-on analysis using statistical software and learn to interpret and present the results. A-F only. (Fall only) (Cross-listed as QHS 601)

TRMD 671 Advanced Medical Parasitology (2)

Consideration of ultrastructure, physiology, biochemistry, in-vitro cultivation and host-parasite relationship of parasites of medical importance. A-F only. Pre: consent. (Alt. years: fall)

TRMD 672 Advanced Medical Virology (2)

In-depth study of the major groups of viruses pathogenic for human; virus replication, host range, pathogenesis, immunology, and epidemiology. Pre: 605 or equivalent, or consent. (Alt. years: fall)

TRMD 673 Advanced Medical Bacteriology (2)

Role of bacteria in infectious diseases, with emphasis on clinical aspects and identification of etiological agents. Pre: 605 or equivalent, or consent.

TRMD 675 Epidemiology of Tropical Infectious Diseases (3)

Epidemiology of infectious diseases as it relates to tropical medicine. Lecture/seminar format. A-F only. Pre: TRMD graduate standing or consent. (Spring only)

TRMD 690 Seminar in Tropical Medicine and Public Health (1)

Weekly discussion and reports on current advances in tropical medicine and public health. Repeatable unlimited times. (Cross-listed as PH 755)

TRMD 695 Plan B Master’s Project (3)

Independent study for students working on a Plan B master’s project. A grade of Satisfactory (S) is assigned when the project is satisfactorily completed. A-F only. Pre: graduate standing in TRMD.

TRMD 699 Directed Research (V)

Directed research in medical microbiology (bacteriology, parasitology, virology). Repeatable unlimited times. Pre: consent.

TRMD 700 Thesis Research (V)

Research for master’s thesis. Approval of department faculty required. Repeatable unlimited times.

TRMD 705 Special Topics in Tropical Medicine (V)

Advanced instruction in frontiers of tropical medicine and public health. Repeatable unlimited times. A-F only. (Cross-listed as PH 756)

TRMD 800 Dissertation Research (V)

Research for doctoral thesis. Approval of department faculty is required. Repeatable unlimited times.