If you have recently tested positive for COVID-19, you may be eligible for a study.
The H051 Study is title Randomized, Double-Blind, Placebo-Controlled, Pilot Clinical Trial of the Safety and Efficacy of Telmisartan for the Mitigation of Pulmonary and Cardiac Complications in COVID-19 Patients’. It is listed in the national clearinghouse for clinical trials (ClinicalTrials.gov) as NCT04360551.
There is still no existing cure for HIV. With advances in HIV research, medications called ‘antiretrovirals’ keep the virus in check and can make the virus ‘undetectable’ in the blood. According to the Centers for Disease Control and Prevention, people with HIV who take HIV medicine as prescribed and get and keep an undetectable viral load (or stay virally suppressed) have effectively no risk of transmitting HIV to their HIV-negative sexual partners. “Undetectable” viral load or “viral suppression” is defined as having less than 200 copies of HIV per milliliter of blood.
The slogan “U=U” has been adapted by more than 60 organizations internationally to encourage HIV testing, adherence to treatment, and reduce stigma.
The website positiveseries.org published four videos detailing the journey of four persons living with HIV and the challenges they faced before becoming undetectable:
“U=U” was one of the central themes of the 4th Hawaii to Zero Conference held last January 10, 2019. The conference was organized by the Hawaii Center for AIDS and the Hawaii State Department of Health Harm Reduction Services Branch.
The 4th Hawaii to Zero HIV Prevention & Cure Conference was held at the Ala Moana Hotel in January 10, 2019. The Hawaii to Zero is an initiative of the Hawaii Center for AIDS with the vision of “Zero new HIV infections, zero deaths from HIV illness, and zero HIV-related stigma.”
The conference was organized by the Hawaii Center for AIDS and the Hawaii State Department of Health Harm Reduction Services Branch and was supported by funding from ViiV Healthcare, Hawai’i State Department of Health, Centers for Disease Control & Prevention, and Gilead Sciences.
The morning sessions focused on HIV prevention and ‘getting to zero’ in Hawai’i, while the afternoon sessions focused on HIV cure-related research. Investigational adjunct therapies, including latency reversal agents, negative checkpoint T cell blockade, and immunomodulatory therapies were presented.
The meeting was attended by about 200 physicians, scientists, community leaders, and persons living with HIV. The 5th Hawaii to Zero conference is set to be held in January 2021.
Dr. Cecilia Shikuma was named this year’s recipient of the Suzanne Richmond-Crum Award. The Harm Reduction Services Branch of the Hawai’i Department of Health confers the award annually to an individual in Hawaii “for outstanding contribution in providing HIV/AIDS services.” The award was conferred in December 1, 2018 at the Church of the Crossroads in Manoa as part of the World AIDS Day commemoration.
The award was established in memory of Suzanne Richmond-Crum, former Director of the Hawaii Seropositivity and Medical Management Program (HSPAMM). Suzanne passed away in 2004 after serving as Director of HSPAMM for more than a decade.
Dr. Shikuma has served as an HIV care provider, researcher, grant reviewer, mentor, and consultant for over thirty years. Her research works on the chronic complications of HIV and her efforts towards an AIDS-free Hawaii through the ‘Hawaii to Zero’ initiative is truly an inspiration.
Dr. Cecilia Shikuma and Dr. Louie Mar Gangcuangco recently visited the Philippines in November 2018 as invited speakers of the Philippine Society for Microbiology and Infectious Diseases (PSMID) and the Mindanao State University-Iligan Institute of Technology (MSU-IIT).
Dr. Shikuma’s plenary lecture at the 40th PSMID annual convention held last November 28, 2018 was entitled, “Clinical implications of HIV pathogenesis in treated and untreated populations.” Dr. Shikuma also met with Dr. Charlotte M. Chiong, Dean of the University of the Philippines College of Medicine (UPCM), to discuss expanding research collaborations between the Hawaii Center for AIDS and UPCM.
Dr. Gangcuangco delivered a lecture on HIV pathogenesis and chronic complications of HIV at the MSU-IIT in November 29, 2018. The invitation was extended by Prof. Clowe Jondonero, Dean of the MSU-IIT College of Nursing. The lecture was attended by more than 200 nursing students, faculty members, and Dr. Franco Teves, Vice Chancellor for Research of MSU-IIT. Other guests include fellow Balik (returning) Scientists of the Department of Science and Technology, Prof. Arnie Alguno and Prof. Arnold Lubguban.
The Philippines is experiencing the fastest-growing HIV epidemic in the western Pacific region, registering more than 1,000 new HIV cases per month. Research collaborations on HIV pathogenesis and prevention are warranted to help curb the epidemic.
November 9, 2018. Governor David Ige signs a proclamation commemorating the 30th anniversary of World AIDS Day . The event was held at the Hawai’i State Capitol and attended by community leaders, including representatives from the Department of Health, Hawai’i Health and Harm Reduction Center, and the Hawai’i Center for AIDS.
Brooks Mitchell in the Department of Tropical Medicine at the john A. Burns School of Medicine was awarded a prestigious ARCS Award.
Education: BS Microbiology; MS Biomedical Sciences (Tropical Medicine)
Goal: Pursue an MD after completing his PhD. He wants to gain clinical knowledge that will better articulate the significance of bench research to clinical research as a physician scientist.
Interest: hiking, swimming, surfing, and free-diving.
While HIV isn’t the death sentence it once was, it appears to cause chronic inflammation and lymph node fibrosis that creates a higher risk of corollary illnesses. Brooks is studying the underlying immunological mechanisms which could lead to cell-targeted therapies that reduce lymphoid tissue fibrosis. He has received several achievement awards and travel scholarships related to his research. The ARCS Scholar Award will help defray living expenses, allowing him to focus on his research.
Find more information and multiple videos at both UH Med Now as well as Tropical Medicine News:
Drs. Cecilia Shikuma, Dominic Chow, and Lishomwa Ndhlovu as well as Graduate Students attend and present at the Conference on Retroviruses and Opportunistic Infections (CROI) 2018 Conference in Boston, MA in the beginning of March 2018. They braved the cold and snowstroms to present our findings to an international audience.
Brooks Mitchell, a PhD student, presents at CROI 2018.
Dr. Dominic Chow, MD, MPH, presents at CROI 2018.
Dr. Louie Mar Gangcuangco, research coordinator for HICFA, at CROI 2018.