To provide elective courses for undergraduates in the biomedical sciences specialties. Repeatable unlimited times.
Analysis of emerging problems and impact in countries on a multidimensional perspective. Repeatable one time. BIOM, NURS, PH, SPA majors only. Pre: consent.
Overview of applied clinical nutrition that includes nutrients, dietary recommendations for healthy populations and medical nutrition therapies for patients with diet related diseases or conditions. Graduate students only. A-F only. Pre: BIOL 171 (or higher) or PHYL 141 or ZOOL 141 or consent.
Instruction in developing clinical research questions and creating a concise protocol that includes a literature review, study design, subject recruitment and sampling, instruments, other measures and bioinformatics, sample size, consent form, budget and timetable. A-F only.
Ethical dilemmas in clinical research are identified and resolved in cases, research on human subjects regulation are discussed. Research misconduct is defined. Ethical considerations in protocol developed in the Designing Clinical Research course are resolved. A-F only. (Cross-listed as CMB 626)
Lectures focus on translational research methods through selected genetic and acquired diseases including cancer, neurodevelopmental, inflammatoryimmune, and metabolic conditions with insight into analyses of DNA, RNA, genomics-proteomics, cell and animal models, and advanced imaging. A-F only. Pre: consent.
Provides training in proposal development. Governance structures of funding agencies; funding opportunities and decisions; review processes; NIH application and processes; reading RFAs; compliance issues; cultural sensitivity; and types of questions using databases are addressed. A-F only.
Introductory lecture-seminar on the conduct of multidisciplinary research from a culturally competent perspective. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)
Explores the foundations of biomedical ethics via small group seminars and discussion, presentations. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)
Develop biomedical ethics through case studies to incite discussions on topics such as gene therapy, gene enhancement, genetic counseling, informed consent, health care professional/patient and investigator/student participant communication, advanced directives and living wills, clinical research in developing countries, clinical research in ethnic minority and socio-economically disadvantaged populations, and non-discrimination in health care and research settings. A-F only.
Explore topics in cultural competence in greater depth, encouraging trainees to address issues from a unified yet flexible conceptual framework. Involves building knowledge, skills and action plans to address a range of learning styles and to appreciate and benefit from diversity. A-F only.
Seminar focuses on teaching participants to work independently and collaborate in order to accomplish specific results. Students will be exposed to group dynamics, communication, healthy competition, conflict resolution, and innovative means of crossing boundaries between departments, organizations, industries and disciplines. Repeatable two times. A-F only.
Focus on heritable disorders, genetic mechanisms, patterns of inheritance, phenotype-genotype correlations, genetic/ environmental factors, clinical diagnoses, genomic and precision medicine.
Conduct research under the direction of a mentor. Participants will be responsible for submission of a proposal, acquisition of IRB approval, and conduct of the project. Repeatable five times or up to 12 credits. BIOM students only. A-F only.
Current methods for analyzing longitudinal and clustered, clinical data through lectures, discussions, and a group analysis. Topic areas include multi-level, multi-state, multi-process, and structural equation models. A-F only. Pre: QHS 601 and QHS 602, or consent.
Students may register on approval of department. CR/NC only. Repeatable unlimited times.
Research for master’s thesis. Repeatable seven times or up to 8 credits. CR/NC only. Pre: consent.
Assess impact on health in disasters and diseases. Enhances research skills related to management and communication. Repeatable one time. BIOM, PH, NURS, and SPA majors only. Pre: consent.
Research for doctoral dissertation. Repeatable unlimited times. CR/ NC only. Pre: consent.
Mathematics preparation for quantitative health sciences. Includes selective topics in
linear algebra, advanced calculus and probability theory. A-F only.
Directed reading/research in quantitative health sciences. Students will work closely with a QHS faculty member or mentor who will guide them through quantitative methodologies and/or the process of conducting a research study. Repeatable three times or up to 12 credits. A-F only.
Provide biostatistical concepts to clinical researchers. Students will obtain the ability to demonstrate an understanding of key biostatistical concepts in clinical research; and interpret statistical findings most commonly reported in clinical and healthcare literature. Graduate students only.
Fundamental biomedical statistics concepts and tools will be introduced, as well as their applications to biomedical data. Students will perform hands-on analysis using statistical software and learn to interpret and present the results. A-F only. (Fall only) (Cross-listed as TRMD 655)
Statistical theory of Linear Model and Generalized Linear Model, algorithms use for estimation, inference concepts, and assessment of goodness-of-fit. Covers Proportional Hazard Model and Generalized Estimating Equations. A-F only. Pre: 601 (with a minimum grade of B) or consent.
Data management and visualization is essential to all aspects of health sciences. Through hands-on experiences in R, will introduce data processing, manipulation, visualization and reproducibility, with an emphasis on clinical, medical, and health science problems. A-F only.
Provides fundamental concepts in bioinformatics with strong emphasis on hands-on training. Topics such as molecular biology, sequence alignment, biological databases, phytogeny,
and genomics including microarray and RNA-sequence analysis. Repeatable one time, but credit earned one time only. Open to nonmajors. A-F only. (Fall only) (Cross-listed with TRMD 653)
Focus on bioinformatics approaches for functional genomics related to DNA, RNA, and protein. It will provide of virus, bacteria, and human genome and bioinformatics approaches to human disease. A-F only. Pre: 610 (or equivalent) (with a minimum grade of B) or consent.
Introduction to clinical trials. Topics include history, definitions/terminology, adverse events, FDA and government regulatory agencies, ethics; monitoring committees, recruitment, introduction to protocol development, basis designs. A-F only.
Covers basic and advanced statistical methods utilized in clinical trials design, conduct, and data analysis. Topics cover statistician’s role in drug development and DSMB,
statistical theory in phases I-IV clinical trial designs and analysis. A-F only. Pre: 601 (or equivalent) with a minimum grade of B or consent.
Provides overview of research related to health in Hawai‘i and advances in quantitative health and clinical research. Topics include ethnic disparities in health, social and cultural factors, ethics, biostatistics and bioinformatics. Repeatable six times. CR/NC only. Pre: consent
Will allow students who are new to using secondary data to become comfortable with accessing the data, forming hypotheses, and designing study proposals. Will introduce examples with basic and advanced techniques. A-F only. Pre: 601 (or equivalent) with a minimum grade of B- .
Introduces students to issues in working with complex data sets and adds the hands-on experience needed to conduct individual research using secondary databases. A-F only. Pre: (601 (or equivalent) and 650) with a minimum grade of B, which can be taken concurrently.
Special topics in quantitative health sciences. Reflects special research interest of QHS faculty or guest lecturers. Repeatable unlimited times. A-F only.
Investigate the roles and responsibilities of the biostatistician as both consultant and collaborator with biomedical researchers, guide students in enhancing problem-solving and
communication skills, and provide opportunity to observe real-life biostatistical consultations. A-F only. Pre: 601 and 602 (or equivalent) with minimum grades of B, and consent.
Under the supervision of biostatistics faculty members, students will have the opportunity to provide statistical
consultations to biomedical researchers and gain hands-on experience conducting biostatistical analysis in solving real-life analytic problems. Repeatable two times, up to six credits. A-F only. Pre: 675 (or concurrent) with a minimum grade of B.
Directed research in quantitative health sciences. Students will work closely with a QHS faculty member or mentor who will guide them through the process of conducting a research study. Repeatable unlimited times. A-F only.