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Quantitative Health Sciences (QHS)

QHS 401 Mathematic Preparation for Quantitative Health Sciences (3)

Mathematics preparation for quantitative health sciences. Includes selective topics in
linear algebra, advanced calculus and probability theory. A-F only.

QHS 499 Directed Reading/Research (V)

Directed reading/research in quantitative health sciences. Students will work closely with a QHS faculty member or mentor who will guide them through quantitative methodologies and/or the process of conducting a research study. Repeatable three times or up to 12 credits. A-F only.

QHS 600 Biostatistics Concepts for Clinical Researchers (3)

Provide biostatistical concepts to clinical researchers. Students will obtain the ability to demonstrate an understanding of key biostatistical concepts in clinical research; and interpret statistical findings most commonly reported in clinical and healthcare literature. Graduate students only.

QHS 601 Fundamentals of Biostatistics (3)

Fundamental biomedical statistics concepts and tools will be introduced, as well as their applications to biomedical data. Students will perform hands-on analysis using statistical software and learn to interpret and present the results. A-F only. (Fall only) (Cross-listed as TRMD 655)

QHS 602 Generalized Linear Model (3)

Statistical theory of Linear Model and Generalized Linear Model, algorithms use for estimation, inference concepts, and assessment of goodness-of-fit. Covers Proportional Hazard Model and Generalized Estimating Equations. A-F only. Pre: 601 (with a minimum grade of B) or consent.

QHS 605 Data Management and Visualization for Health Sciences (3)

Data management and visualization is essential to all aspects of health sciences. Through hands-on experiences in R, will introduce data processing, manipulation, visualization and reproducibility, with an emphasis on clinical, medical, and health science problems. A-F only.

QHS 610 Bioinformatics I (3)

Provides fundamental concepts in bioinformatics with strong emphasis on hands-on training. Topics such as molecular biology, sequence alignment, biological databases, phytogeny,
and genomics including microarray and RNA-sequence analysis. Repeatable one time, but credit earned one time only. Open to nonmajors. A-F only. (Fall only) (Cross-listed with TRMD 653)

QHS 611 Bioinformatics II (3)

Focus on bioinformatics approaches for functional genomics related to DNA, RNA, and protein. It will provide of virus, bacteria, and human genome and bioinformatics approaches to human disease. A-F only. Pre: 610 (or equivalent) (with a minimum grade of B) or consent.

QHS 620 Introduction to Clinical Trials (2)

Introduction to clinical trials. Topics include history, definitions/terminology, adverse events, FDA and government regulatory agencies, ethics; monitoring committees, recruitment, introduction to protocol development, basis designs. A-F only.

QHS 621 Design and Analysis of Clinical Trials (2)

Covers basic and advanced statistical methods utilized in clinical trials design, conduct, and data analysis. Topics cover statistician’s role in drug development and DSMB,
statistical theory in phases I-IV clinical trial designs and analysis. A-F only. Pre: 601 (or equivalent) with a minimum grade of B or consent.

QHS 646 Quantitative Health and Clinical Research Seminar (1)

Provides overview of research related to health in Hawai‘i and advances in quantitative health and clinical research. Topics include ethnic disparities in health, social and cultural factors, ethics, biostatistics and bioinformatics. Repeatable six times. CR/NC only. Pre: consent

QHS 650 Secondary Data Analysis (3)

Will allow students who are new to using secondary data to become comfortable with accessing the data, forming hypotheses, and designing study proposals. Will introduce examples with basic and advanced techniques. A-F only. Pre: 601 (or equivalent) with a minimum grade of B- .

QHS 651 Secondary Data Analysis Practicum (2)

Introduces students to issues in working with complex data sets and adds the hands-on experience needed to conduct individual research using secondary databases. A-F only. Pre: (601 (or equivalent) and 650) with a minimum grade of B, which can be taken concurrently.

QHS 670 Special Topics in Quantitative Health Sciences (V)

Special topics in quantitative health sciences. Reflects special research interest of QHS faculty or guest lecturers. Repeatable unlimited times. A-F only.

QHS 675 Biostatistical Consulting (2)

Investigate the roles and responsibilities of the biostatistician as both consultant and collaborator with biomedical researchers, guide students in enhancing problem-solving and
communication skills, and provide opportunity to observe real-life biostatistical consultations. A-F only. Pre: 601 and 602 (or equivalent) with minimum grades of B, and consent.

QHS 676 Biostatistical Consulting Practicum (V)

Under the supervision of biostatistics faculty members, students will have the opportunity to provide statistical
consultations to biomedical researchers and gain hands-on experience conducting biostatistical analysis in solving real-life analytic problems. Repeatable two times, up to six credits. A-F only. Pre: 675 (or concurrent) with a minimum grade of B.

QHS 699 Directed Research (V)

Directed research in quantitative health sciences. Students will work closely with a QHS faculty member or mentor who will guide them through the process of conducting a research study. Repeatable unlimited times. A-F only.