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Anatomy, Biochemistry and Physiology

ANAT 499 Directed Reading/Research (V)

ANAT 545 (Alpha) Unit VII Anatomy Electives (V)

Advanced study of human anatomy by dissection and individual observation of surgical procedures. (C) topics in reproductive biology. Repeatable two times. CR/NC only. Pre: FMCH, MED, OBGN, PED, PSTY, SURG 531 or 532; or consent.

ANAT 599 Independent Study in Anatomy (1)

Elective course for advanced medical students. (B) human gross anatomy; (C) histology; (D) research in anatomy and developmental biology. CR/NC only. Repeatable three times. Pre: consent for (B) and (C); MDED 551 for (D).

ANAT 603 Lower Extremity, Thorax, and Abdomen (3)

Human gross anatomy dissection of the lower extremity, thorax, and abdomen. Emphasis is placed on muscles, function, innervation, and vascular supply. Repeatable one time. Enrolled in DRB or KRS graduate programs (including Biomed Sci-Anat/ RepoBiol & Phys majors) only or consent. A-F only. (Spring only) (Cross-listed as KRS 603)

ANAT 604 Upper Extremity, Head, Neck, and Spine (3)

Human gross anatomy dissection of the upper extremity, head, neck, and spine. Emphasis is placed on muscles, function, innervation, and vascular supply. Repeatable one time. Enrolled in DRB or KRS graduate programs (including Biomed Sci-Anat/ RepoBiol & Phys majors) only or consent. A-F only. (Fall only) (Cross-listed as KRS 604)

ANAT 607 Human Embryology (2)

Systematic study of human development, including implantation, placentation, basics of development of each organ system with reference to pertinent congenital anomalies and their surgical repair. Pre: 603 or 604. Recommended: gross anatomy course.

ANAT 612 Seminar in Anatomy Teaching (V)

Effective teaching methods, organization of courses in anatomical sciences, development and evaluation of exams, experience in teaching with audiovisual/ computer aids. Open to graduate students in physiology or KRS. CR/NC only. Repeatable eight times, up to 32 credits. Pre: 603 and 604.

ANAT 699 Directed Research (V)

Repeatable unlimited times.

ANAT 700 Thesis Research

Repeatable unlimited times. (V) Pre: admission to candidacy (master’s program).

ANAT 800 Dissertation Research (V)

Repeatable unlimited times.

BIOC 241 Fundamentals of Biochemistry (3)

Biological chemistry stressing integration of concepts of general, inorganic, and biochemistry and application to life chemistry. Pre: beginning algebra and high school science.

BIOC 341 Elements of Biochemistry (3)

Biochemical principles and concepts as applied to living systems, including sufficient organic chemistry to understand these principles. Pre: 241 or consent.

BIOC 441 Basic Biochemistry (4)

Principles of biochemistry, applicable to medicine and real-life situations, involving metabolism of carbohydrates, lipids, proteins, nucleic acids, and vitamins. Taught by biomedical researchers. Evaluated based on exams, quizzes, homework, and group presentation.

BIOC 499 Directed Research and Reading (V)

Independent research or selected reading of current literature in the area of biochemistry and biophysics. Repeatable unlimited times. Pre: consent.

BIOC 545 Topics in Biochemistry (V)

Fourth-year elective in which medical students take an in-depth study of selected topics in biochemistry. Pre: fourthyear medical student or consent.

BIOC 595 Highlights of Organ-System Biochemistry (1)

Provides highly interactive, small group discussions on concepts of biochemistry important to the various organ systems; such as cardiac, respiratory, hematology, gastrointestinal, endocrine, musculoskeletal and neurological systems, and relevant to clinical medicine. MD majors only. CR/NC only. Pre: MDED 554. (Fall only)

BIOM 499 Directed Research and Reading (V)

To provide elective courses for undergraduates in the biomedical sciences specialties. Repeatable unlimited times

BIOM 601 Global Health and Medicine: Emerging Problems and Impact (3)

Analysis of emerging problems and impact in countries on a multidimensional perspective. Repeatable one time. BIOM, NURS, PH, SPA majors only. Pre: consent.

BIOM 640 Introduction to Clinical Research (3)

Instruction in developing clinical research questions and creating a concise protocol that includes a literature review, study design, subject recruitment and sampling, instruments, other measures and bioinformatics, sample size, consent form, budget and timetable. A-F only.

BIOM 641 Legal and Regulatory Issues and Bioethics (2)

Ethical dilemmas in clinical research are identified and resolved in cases, research on human subjects regulation are discussed. Research misconduct is defined. Ethical considerations in protocol developed in the Designing Clinical Research course are resolved. A-F only. (Cross-listed as CMB 626)

BIOM 644 Translational Research Methods (2)

Lectures focus on translational research methods through selected genetic and acquired diseases including cancer, neurodevelopmental, inflammatoryimmune, and metabolic conditions with insight into analyses of DNA, RNA, genomics-proteomics, cell and animal models, and advanced imaging. A-F only. Pre: consent.

BIOM 645 Clinical Protocol Development (3)

Provides training in proposal development. Governance structures of funding agencies; funding opportunities and decisions; review processes; NIH application and processes; reading RFAs; compliance issues; cultural sensitivity; and types of questions using databases are addressed. A-F only.

BIOM 646 Clinical Research Seminar (1)

Provides overview of research related to health and health disparities in Hawai‘i. Seminar topics include ethnic disparities in health research, Native Hawaiian health, childhood research initiatives, fitness and obesity, social and cultural factors and ethics. Repeatable six times. A-F only. Pre: consent.

BIOM 647 Cultural Competence in Biomedical Research I (3)

Introductory lecture-seminar on the conduct of multidisciplinary research from a culturally competent perspective. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)

BIOM 648 Foundations of Biomedical Ethics (3)

Explores the foundations of biomedical ethics via small group seminars and discussion, presentations. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)

BIOM 649 Advanced Ethics in Biomedical Research II (3)

Develop biomedical ethics through case studies to incite discussions on topics such as gene therapy, gene enhancement, genetic counseling, informed consent, health care professional/patient and investigator/student participant communication, advanced directives and living wills, clinical research in developing countries, clinical research in ethnic minority and socio-economically disadvantaged populations, and non-discrimination in health care and research settings. A-F only.

BIOM 650 Cultural Competence in Biomedical Research II (3)

Explore topics in cultural competence in greater depth, encouraging trainees to address issues from a unified yet flexible conceptual framework. Involves building knowledge, skills and action plans to address a range of learning styles and to appreciate and benefit from diversity. A-F only.

BIOM 651 PhD Team Building Seminar (V)

Seminar focuses on teaching participants to work independently and collaborate in order to accomplish specific results. Students will be exposed to group dynamics, communication, healthy competition, conflict resolution, and innovative means of crossing boundaries between departments, organizations, industries and disciplines. Repeatable two times. A-F only.

BIOM 654 Medical Genetics (2)

Focus on heritable disorders, genetic mechanisms, patterns of inheritance, phenotype-genotype correlations, genetic/ environmental factors, clinical diagnoses, genomic and precision medicine.

BIOM 660 Mentored Research Practicum (V)

Conduct research under the direction of a mentor. Participants will be responsible for submission of a proposal, acquisition of IRB approval, and conduct of the project. Repeatable five times or up to 12 credits. BIOM students only. A-F only.

BIOM 667 Advanced Biostatistics for Clinical Research (3)

Current methods for analyzing longitudinal and clustered, clinical data through lectures, discussions, and a group analysis. Topic areas include multi-level, multi-state, multi-process, and structural equation models. A-F only. Pre: 642 and 643, or consent.

BIOM 699 Directed Research (V)

Students may register on approval of department. CR/NC only. Repeatable unlimited times.

BIOM 700 Thesis Research (V)

Research for master’s thesis. Repeatable unlimited times. CR/NC only. Pre: consent.

BIOM 701 Disasters and Pandemics: Medical and PH Management and Risk Communication (3)

Assess impact on health in disasters and diseases. Enhances research skills related to management and communication. Repeatable one time. BIOM, PH, NURS, and SPA majors only. Pre: consent.

BIOM 800 Dissertation Research (V)

Research for doctoral dissertation. Repeatable unlimited times. CR/ NC only. Pre: consent.

PHYL 103 Human Physiology and Anatomy (5)

Introduction to human physiology and anatomy designed to serve the needs of dental hygiene students and others interested in pursuing health-related careers.

PHYL 103L Physiology and Anatomy Lab (1)

Laboratory to complement 103. Co-requisite: 103.

PHYL 141 Human Anatomy and Physiology (3)

Anatomy, histology, physiology, biochemistry, genetics of human organ systems presented in integrated anatomy-physiology format. Priority to students in nursing. Pre: high school chemistry.

PHYL 141L Human Anatomy and Physiology Lab (1)

Anatomy, histology, physiology, biochemistry, genetics of human organ systems presented in integrated anatomy-physiology format. Priority to students in nursing. Pre: 141 (or concurrent) or consent.

PHYL 142 Human Anatomy and Physiology (3)

Continuation of 141. Pre: should have an understanding of basic physiology concepts as presented in 141 or equivalent.

PHYL 142L Human Anatomy and Physiology Lab (1)

Anatomy, histology, physiology, biochemistry, genetics of human organ systems presented in integrated anatomy-physiology format. Priority to students in nursing. Pre: 142 (or concurrent) or consent.

PHYL 301 Advanced Anatomy and Physiology (4)

Integrated presentation of human anatomy and physiology. An optional laboratory (PHYL 301L) is available separately. Pre: BIOL 171 and BIOL 172, or any PHYL course; and CHEM 161 (or higher) or any BIOC course; or consent.

PHYL 301L Human Anatomy and Physiology Lab (1)

Laboratory study of human anatomy and physiology by means of models, histology slides, experiments, and demonstrations. Co-requisite: 301 or consent.

PHYL 302 Advanced Anatomy and Physiology (4)

Continuation of 301. Pre: 301/301L or consent.

PHYL 302L Human Anatomy and Physiology Lab (1)

Continuation of 301L. Pre: 301/301L, or consent. Co-requisite: 302.

PHYL 401 Human Physiology: Organ Systems (4)

Basic function of the major organ systems in man. Covers cardiovascular, respiratory, renal, acid-base, and gastrointestinal physiology. Pre: 302 or equivalent with consent.

PHYL 402 Human Physiology: Integrative Systems (4)

Senior-level course in integrative systems (central nervous system and endocrinology). Complements 401. Pre: 401 and either BIOC 341 or CHEM 152, or consent.

PHYL 405 Applied Muscle Physiology (3)

Science and technology of strength training. Anatomy, kinesiology, physics, and physiology applied to development of muscular strength and mass. Repeatable one time. A-F only. Pre: 302; or consent.

PHYL 499 Directed Reading or Research (V)

Students will learn fundamental concepts and multiple techniques in molecular biology, physiology, and histology for cardiovascular research through the projects in the lab. Repeatable unlimited times, but credit earned to two credits only. Junior or senior standing only. CR/NC only.

REPR 499 Directed Reading/Research (V)

Repeatable unlimited times.

REPR 611 Seminar in Biomedical Sciences (1)

Presentation and discussion of current research topics in biomedical sciences. Repeatable nine times. Pre: consent. (Cross-listed as CMB 611)

REPR 699 Directed Research (V)

Repeatable unlimited times.

REPR 700 Thesis Research (V)

Repeatable unlimited times. Pre: admission to candidacy (master’s program).

REPR 705 Special Topics in Reproductive Biology (V)

In-depth discussion of selected areas of reproductive biology, with special emphasis on recent research results and methodologies. May be retaken for credit. Pre: consent.

REPR 800 Dissertation Research (V)

Repeatable unlimited times. Pre: admission to candidacy (PhD program).