Departmental Assessment Update - Medicine Report

Department: Biomedical Science: Cell and Molecular Biology
Program: M.S. and Ph.D.
Level: Graduate

1. Has your program developed learning outcomes? If yes, please list.

 Master of Science in Biomedical Sciences (Cell and Molecular Biology) 

1. Sufficient breadth and depth of knowledge to assume responsibility for teaching classes in Cell and Molecular Biology at least at the undergraduate level, and teaching experience in these and related topics;

 

1. Knowledge of the process of research, including: familiarity with techniques for searching the literature; principles of measurement; and practical experience in the design and conduct of scientific experiments, collection of data, and interpretation of data sufficient to enable them to interpret current literature, and to embark upon the next (doctoral) level of development as researchers;

 

1. Familiarity with the mechanics of scientific reporting sufficient to enable them to prepare a publication for a scholarly journal;

 

1. Experience with oral presentation of material sufficient to enable them to prepare and deliver reports on their work at seminars or meetings of scientific societies;

 

1. A degree of understanding and scientific maturity sufficient to enable them to assess the work of others;

 

1. An understanding of the administrative procedures common to academic departments.

 

1. PhD in Biomedical Sciences (Cell and Molecular Biology)

 

1. Sufficient breadth and depth of knowledge to assume responsibility for teaching classes in Cell and Molecular Biology at the undergraduate level, and sufficient sophistication in one specialty area of Cell and Molecular Biology to teach medical and graduate level course material in that area;

 

1. Specialized knowledge in an area of research, including familiarity with the literature and techniques common to their area of specialization; and practical experience in the design and conduct of scientific experiments, collection of data, and interpretation of data sufficient to enable them to initiate and continue research successfully as independent investigators and to supervise student work in that area;

 

1. Familiarity with the mechanics of scientific reporting sufficient to enable them to publish their work in scholarly journals;

 

1. Experience with oral presentation of material sufficient to enable them to prepare and deliver reports on their work at seminars or meetings of scientific societies;

 

1. A degree of understanding and scientific maturity sufficient to enable them to assess and criticize constructively the work of others;

 

1. An understanding of the administrative procedures common to academic departments.

2. If your program has learning outcomes, where are they published (e.g., department web page)?

These student learning outcomes (SLOs) are all listed on the Cell and Molecular Biology Graduate Program web page at http://www.hawaii.edu/graduatestudies/fields/html/departments/cd/cmb/cmb.htm , in the Cell and Molecular Biology Handbook, and portions are distributed to prospective applicants by e-mail. 

3. Do your faculty list course learning outcomes on their syllabi?

All Cell and Molecular Biology courses have descriptions and learning outcomes in their syllabi.  

4. Does your program have a curriculum map that links course outcomes to program outcomes? If so, please include.

. SLO 1, Knowledge:  Courses:   

Except for required courses, the program of study will be tailored to the needs and future career plans of each individual graduate student.  A minimum of 30 credits is required for the MS degree.  There is not a specific credit requirement for the PhD.  Once admitted to PhD candidacy, the student’s advisory committee determines what further coursework, if any, the student shall take. 

Required courses for incoming MS and PhD students include the first year core course, CMB 621-622, Cell and Molecular Biology, the Ethics in Biomedical Research course, CMB 626, and additional courses as required by each student’s academic program.  

Most students will do some directed reading or directed research, especially Plan B MS students and PhD students who, for whatever reason, have not begun a research program under a faculty mentor who will chair their Advisory Committee.  Students will enroll in CMB 699 in order to receive credit for this work, with the number of credits being agreed upon by the faculty conducting the 699, the Chair of the Graduate Program Committee, and the student. 

Incoming PhD students may petition the Graduate Program Committee to be exempted from these required courses when the student has already satisfactorily completed equivalent courses at another institution, but in general, students should expect that they will take these courses. 

            B. SLO 1, Teaching 

      Graduate students are encouraged to participate in teaching by demonstrating in laboratory sessions, particularly within their intended area of specialty.  Their participation as Graduate Teaching Trainees should bring them into direct contact with students and afford them an appreciation of the problems associated with the administration of courses.  To this end, Graduate Teaching Trainees should participate in meetings of course committees and they should also attend the lectures.  Whenever possible, students will be permitted to select the courses in which they will instruct; however, instances may arise where it will be necessary to assign individuals to specific courses within the general area of their competence. 

      A maximum of 10 hours/week may be spent in teaching, except when students receive their major financial support in the form of a teaching stipend (Graduate Teaching Assistantship).  Students holding Graduate Teaching Assistantships will be assigned duties in accordance with Graduate Division guidelines.   

      C. SLO 2, Research:   

The first year graduate student will consult with the mentor to choose a research project early in the graduate program.  Following passage of the Qualifying Exam, the graduate student and the advisor are encouraged to informally discuss the possible projects with potential members of the Advisory Committee and/or other faculty members in order to determine the scientific feasibility of the research scheme and suitability with respect to departmental facilities and personnel.  Based on these discussions, the graduate student and mentor should complete Appendix 1 (Initial Research Summary) as soon as feasible and submit it to the Graduate Program Committee for approval.   

      Following approval of this initial research proposal, the graduate student will be required to meet with his/her Advisory Committee and present a final research proposal.  This presentation should establish a comprehensive background for the project and preliminary results, if available, should be discussed.  This proposal should include details of the research program with the experimental particulars.    The proposal will be subject to approval by the Advisory Committee and forwarded to the Departmental Graduate Committee for final approval.  If significant problems are identified at this time, the student will present a revised program approximately two months later. 

The Graduate Program Committee will review each graduate student’s work at the end of the academic year.  The graduate student and his/her advisor will meet with the Committee to review the student’s progress for the past academic year.  As well, a tentative schedule for the Comprehensive Examination will be provided.  The graduate student is required to complete the form “Annual Review of Graduate Student’s Progress”  (Appendix 2, page 11) and present the information to the Departmental Graduate Committee during his/her annual review. 

      D. SLO 3, 4, 5, Scientific Maturity:   

A graduate student’s academic maturity is nurtured largely through his/her exposure to the scientific acumen of departmental colleagues.  The active participation of graduate students in seminars, discussions and study groups accelerates this process.  In order to stimulate the development of scientific maturity: 

1. A graduate student in the MS program will give one seminar near the completion of the program, typically in the second year.  A PhD student will give one seminar in the second year of his/her program and a second seminar near completion of the degree.  In the case of a MS student who transfers to the PhD program, the seminar typically given in the second year near completion of the MS will serve as a portion of the Qualifying Examination;

 

1. Graduate students should participate in study groups related to the area of their specialization where appropriate.  These study groups provide a situation in which students can present and evaluate their own work as well as that of others in an informal atmosphere;

 

1. Graduate students are ordinarily expected to attend special seminars arranged by the Cell and Molecular Biology Graduate Program or seminars in other departments when appropriate;

 

1. Graduate students will present a written report of their research once annually to the Graduate Program Committee.  Additional written reports may be requested by the Chairperson of the Advisory Committee.  This gives the student an opportunity to formulate his/her progress in writing.  Parts of this report may be useful in the preparation of the thesis;

 

1. Graduate students will participate in scientific meetings to the extent that funds for travel allow.

 

E. SLO 6, Administrative Procedures:   

Graduate students will be exposed whenever practicable to the processes of decision making and administration of the Department.  This exposure will be achieved in part by assigning graduate students to sit on committees of the Department, and they may serve as assistants to faculty members having specific responsibilities within the Departmental structure. 

All graduate students will be permitted to attend open faculty meetings of the Department as observers.  Each autumn the graduate students of the Department will elect a graduate student representative who will have full voting privileges at these meetings, and with whom the Department can consult on any matters concerning graduate student affairs.  Students will also elect a representative to the campus-wide Graduate Student Organization (GSO). 

5. Does your program benchmark or have goals for student performance? (e.g. 70% students will graduate within 5 years)

All MS and Ph.D. students are expected to pass the qualifying exam in their second year.  In the past three years, 95% of students passed the exam. 

The qualifying exam is composed of two parts:

Part I (70% of grade): Written qualifying exam.

This exam will be administered on xxxxx. The format of this 1 hour exam will be a closed test comprising 50 multiple choice questions. These questions will be similar in style and difficulty to questions from the Cell and Molecular Biology GRE examination. The exam will test a wide range of fundamental concepts in cell biology, cellular biochemistry and molecular biology, as well as areas of topical interest in our field.

 

Part II (30% of grade): Paper presentation

This exam will be administered between xxxxx and xxxxx. This exam will last approximately 1 hour. Students are asked to prepare a scientific paper and present it to a faculty committee in a ‘journal club’ format. The paper should be selected from a peer-reviewed journal. The paper can be within or outside the student’s research area, but papers by the student’s advisor or the student are not permitted. The paper should be a primary research article, not a review. The student will present the paper orally, and should supply an electronic presentation that comprises the paper text (as a PDF) only (to Dr Turner at least 7 days prior to the date of the exam). No additional material (powerpoint presentation, written notes) will be allowed in the examination. The student is expected to present using the published text and figures of the paper only. The exam will test the student’s ability to present orally, to describe and evaluate scientific methods and data, and to critically discuss the conclusions of a scientific article. 

 MS or Ph.D. students have seven years to complete their respective programs.  Most MS students complete their MS in 2-3 years.  Most Ph.D students complete their Ph.D.s in 5-7 years. 

6. Other than GPA, what data/evidence is used to determine that graduates have achieved stated outcomes for the degree? (i.e. capstone project, class assignment)

A. Written examinations include midterm and final exams in the Fall and Spring semesters for the core course, CMB 621-622, Cell Molecular Biology, that is required of all first year Ph.D. students, and written qualifying exams given in the fall of the second year to all Ph.D. students. Exam questions are written and graded by a cross-section of the CMB graduate faculty for both the CMB course and qualifying exam, and results tabulated by the graduate program administrator. Written exams are the main basis for grades in our courses.  These are constructed, as much as possible, using questions with which we have prior experience.  They are intended to define a minimal competence in the subject matter of each course.  Together with other behaviors defined by the instructor (class participation, reviewing a classic or recent paper, literature review paper, etc.) they form the basis for the course grade.

B. Literature review papers are part of the evaluation scheme in some courses.  They are intended to exercise literature search techniques, critical thinking, and expository writing skills.  They are evaluated for these attributes by the faculty who teach the subject matter of the paper.

C. The integrative course, Cell and Molecular Biology, uses essay exams to test students’ ability to explain interrelationships between organ systems in the context of a global stressor (exercise), or to explain why certain phenomena are important to homeostasis in this context.

D.  Presentations at Scientific Meetings

E.  Peer-reviewed publications

7. Who interprets the evidence of student learning?

Faculty in the Cell and Molecular Biology Program assess student learning.  

All of our programs have a “culminating experience”.  These are: For Plan A MS students, the masters degree thesis; for Plan B MS students, the plan B paper (which is either an in-depth literature review, or the literature review, problem definition and experimental design for a research project); for PhD students, the doctoral dissertation. 

These culminating experiences are the basis for judging the attainment of research expertise, and the acquisition of scientific maturity.  Each paper/thesis/dissertation is reviewed by a faculty committee chosen for background in the relevant subject matter.  To the extent that deficiencies are identified in the student’s product, remediation of those deficiencies becomes an opportunity for further, focused, development of the student. 

 

8. How are the assessment data/results used to inform decisions concerning the curriculum and administration of the program?

The Cell and Molecular Biology Program assesses student progress regularly.  The Education Cell and Molecular Biology Committee monitors student progress.  The committee also assesses student's learning relative to courses and exams.  Recommendations are made to the chair of the program and usually implemented.    

9. What attempts are made to monitor students’ postgraduate professional activities?

Annually,  questionnaires are sent out to the Cell and Molecular Biology faculty regarding the status of student's publications, scientific presentations, and current position .  The information is stored electronically and in hard copies by the program administrator and chair of the program.  The information is shared with Cell and Molecular Biology faculty and students at the biannual retreats.  

Publications of Research Completed by Current Students During Their Training
Name(years in Training)	Publication (Authors, Year,Title, Journal)
Agsalda, Melissa (2005-present)	Kusao I, Agsalda M, Troelstrup D, Villanueva N, Shiramizu B (2008) Chemotoxicity recovery of mitochondria in non-Hodgkin lymphoma resulting in minimal residual disease. Pediatric Blood & Cancer, 51:193-7, 2008.
Archer, Crystal   (2006-present)	Groll M, Schellenberg B, Bachmann A, Archer CR, Huber R, Powell TK,    Kaiser DM (2008) A plant pathogen virulence factor inhibits the eukaryotic proteasime by a novel mechanism. Nature. April Vol 452:755-759.
Cochrane, K (2002-present)	Lendvay TS, Sweet R, Han CH, Soygur T, Cheng JF, Plaire JC, Charleston JS, Charleston LB Bagai S, Cochrane K, Rubio E, Bassuk JA (2007) Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction.  Am J Physiol Renal Physiol.2007 Oct;2393(4):F1147-56. Epub 2007 Jul 3. Bassuk, JA, Cochrane K Mitchell ME (2004) Induction of Urothelial Cell Proliferation by Fibroblast Growth Factor-7 in RAG1-Deficient Mice. Bladder Disease: Research Concepts and Clinical Applications. Kluwer Academic/Plenum Press. Montgomery-Brock DR, Shimojo RY, Cochrane K (2003) Increased Water Temperature Improves Survival of TSV-Exposed Shrimp. Global Aquaculture Advocate. Vol 6, Issue 4.
Coussens, MJ (2004-present)	Narala SR, Allsopp RC, Wells TB, Zhang G, Prasad P, Coussens MJ, Rossi DJ, Weissman IL, Vaziri H (2008) SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase acitivity. Mol Cell Biol/19, 1201-19. Coussens M, Maresh G, Yanagimachi R, Maeda G, Allsopp R(2008) SIRT1 deficiency attenuates spermatogenesis and germ cell function. PLos ONE.3(2): e1571 Coussens PM, Coussems MJ, Tooker BC, Nobis W (2004) Structure of the bovine natural resistance associated macrophage protein (NRAMP1)gene and identification of a novel polymorphism. DNASeq. 15(1):15-25. Coussens, PM, Tooker B, Nobis W, Coussens MJ (2001) Genetics Characterization of the NRAMP1 Gene.  Research Forum 2001, Michigan State University, East Lansing, MI. Coussens PM, Tooker BC, Nobis W, Coussens MJ. (2001) Genetics and Genomics of Susceptibility to Mycobacterial Infection in Cattle. Initiative for Future Agriculture and Food Systems 2001.
Diller, Karl (2005-present)	4 Books, over 60 articles Diller, Karl(2007) chapter in a fully referenced book. Cradle of Language. Oxford Press.
Dominguez, Kenneth (2005-present)	Boaz SM, Dominguez K, Shaman JA, Ward WS(2008) Mouse spermatozoa contain a nuclease that is activated by pretreatment with EGTA and subsequent calcium incubation. Jour of Cellular Biochemistry, 103:1636-1645, 2008.
Hew, Brian (2002-present)	Fritzinger DC, Hew BE, Thorne M, Panfgburn MK, Janssen BJ, Gros P and Yogel C-W(2008) Human C3 derivatives with cobra venom factor-like functions for therapeutic complement depletion. Dev Comp Immunol; accepted for pub Fritzinger DC, Hew BE, Lee JQ, Vogel C-W(2007) Human C3/cobra venom factor hybrid proteins for therapeutic complement depletion: in vivo activity and fine mapping of important domains. Mol Immunol 2007: 44: 3945. Fritzinger DC, Hew BE, Thorne M, Vogel CW (2004) Functional Characterization of cobra venom factor/cobra C3 hybrid proteins. Mol. Immunol. 41, 230. Hew BE, Thorne M, Fritzinger DC, Vogel CW (2004)Humanized cobra venom factor (CVF): Generation of Human C3 derivatives with CVF-like function.  Mol Immunol. 41,244 Kock MA, Hew BE, Bammert H, Fritzinger DC, Vogel CW (2004) Structure and function of recombinant Cobra Venom Factor. J Biol Chem. 279, 30836-30843. Vogel CW, Fritzinger DC, Hew BE, Thorne M (2004) Generation of “humanized cobra venom factor” for therapeutic complement depletion. Third International Conference on Innate Immunity. Crete, Greece. Vogel CW, Fritzinger DC, Hew BE, Thorne M, Bammert, H (2004) recombinant cobra venom factor. Mol Immunol. 41, 91-199. Fritzinger DC, Hew BE, Wehrhahn D, Vogel CW (2003) Functional Characterization of Cobra Venom Factor/Cobra C3 Hybrid Protein. Mol Immunol. 40, 199.
Naeole, CKM (2002-present)	Naeole CKM and Haymer D. (2003) Use of oligonucleotide arrays for molecular taxonomic studies of closely related species in the oriental fruit fly (Bactrocera dorsalis) complex. Molecular Ecology Notes 3: 662-665.
Seki, Jennifer (2004-present)	Wallick CJ, Gamper I, Thorne M, Feith DJ, Yakasaki K, Wilson SM, Seiki JA (2005) Key role for p27-Kip-1 retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell arrest in MYCN-amplified human neuroblastoma cells. Oncogene. 1-13.
Squires, JE (2003-present)	Mutsvangwa T, Gilmore J, Squires JE, Lindinger MI, McBride BW. (2004) Chronic metabolic acidosis increases mRNA levels for components of the ubiquitin-mediated proteolytic pathway in skeletal muscle of dairy cows. J Nutr. 134:558-61. Squires JE, Sun J, Caffrey JL, Yoshishige D, Mallet RT. (2003) Acetoacetate augments beta-adrenergic inotropism of stunned myocardium by an antioxidant mechanism. Am J Physiol Heart Circ Physiol. 284:H1340-7
Takeuchi, KK (2002-present)	Kanemaru KK, Tuthill MC, Takeuchi KK, Sidell N, wada RK(2007) Retinoic acid induced downregulation of MYCN is not mediated through changes in Spl/Sp3. Tuthill MC, Wada RK, Arimoto JM, Sugino CN, Kanemaru KK, Takeuchi KK, Sidell N(2003)  N-myc oncogene expression in neuroblastoma is driven by Sp1 and Sp3.  Mol Genet Metab 80:272-280, 2003.
Tarnay, J (2001-present)	Tarnay, J.   Tarnay JN, F. Szeri, A. Iliás, T. Annilo, C. Sung, O. Le Saux, A. Váradi, M. Dean, C.D. Boyd, and S. Robinow (2004). The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.  Insect Molecular Biology Oct;13(5):539-4
Teeters,Kelsa (2004-present)	Jourdan-LeSaux, Teeters K, Orozco C, Stauder S, Tam EK (2004) Effects of IL-4, IL-13, and TGFB2 on human lung fibroblasts. Amer Journal of Respiratory Cell and Molec Biology.
Young-Robbins SS (2005-present)	Borthakur PB, Orozco CC, Young-Robbins SS, Haselkorn R, Callahan SM. (2005) Inactivation of patS and hetN causes lethal levels of heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. PCC 7120 Mol Microbiol. 57:111-23.

 

NAME

ENTERED

CONFERENCES

DATE

PRESENTED

            Entered

Agsalda, Melissa	PhD 2005	XVII International AIDS Conference/Mexico City                :	2008/Aug	Poster
		Society of Microbiology      8th International Symposium of Neuro Virology	2008/May	Poster
		Psychiatric Geonomics: Applications of Clinical Practice Conference	2007/Oct	Poster
		Pediatric Academic Societies/Society for Pediatric Research Annual Meeting	2007/July	Poster
		Annual Biomedical Sciences Symposium UH	2007/Mar	Poster
		CMB Program Graduate Retreat	2007/Aug	Oral
Archer, Crystal	PhD 2006	CMB Graduate Student Retreat/Honolulu      Biomedical Sciences Symposium/Honolulu	2008/Aug         2007/March	Oral     Poster
Barnhill, Jason	PhD 2006	None
Caliva, Maisel	PhD 2007	ASBMB Annual Meeting      Butler U Undergrad Research Conference	2006    2005	Poster   Poster
Campora, Cara	PhD 2004	Experimental Biology Conference/Wash DC	2007/April	Poster
		Experimental Biology Conference/San Francisco	2006/April	Poster
		Biomedical Sciences Symposium/Honolulu	2006/April	Poster
		Biomedical Science Symposium/Honolulu	2005/April	Poster
		3rd Symposium on Harmful Algae in the US	2005/Oct	Poster
Cochrane, Kimberly	PhD 2005	CMB Graduate Program Retreat	2007/Aug	Oral
		INBRE Poster Session	2006/July	Poster
		Biomedical Sciences Symposium/Honolulu	2005/April	Poster
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
Cogbill(Tarnay), Jolene	PhD 2003	CMB Graduate Program Retreat	2007/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2007/March	Poster
		Biomedical Sciences Symposium/Honolulu	2006/April	Poster
		Biomedical Sciences Symposium/Honolulu	2005/April	Poster
Coussens, Matthew J.	PhD 2004	Annual ISSCR Conference/Philadelphia	2008	Poster
		CMB Graduate Program Retreat	2007/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2007/Mar	Poster
		International Society for Stem Cell Research/Australia	2006	Oral/Poster
		CMB Graduate Program Retreat	2005	Oral
Diller, Karl	PhD 2005	CMB Program Graduate Retreat      Cradle of Language Conference/Stellenbosch, South Africa	2007/Aug         2006/Nov	Oral   Oral/Poster
		CMB Graduate Program Retreat	2005/Aug	Oral
Dominguez, Kenneth	PhD  2008	Annual  Meeting of Society for the Study of Reproduction/Hawaii	2008/May	Poster
		CMB Graduate Program Retreat	2007/Aug	Oral
		INBRE Poster session	2007	Poster
Gawecka, Joanna	PhD 2005	None
Hara, Cynthia	MS  2004	Biomedical Sciences Symposium/Honolulu	2007/April	Poster
Haines, Bryan	PhD 2004	CMB Graduate Student  Retreat      Biomedical Sciences Symposium/Honolulu	2005/Aug              2005/April	Oral           Poster
Hew, Brian	PhD 2005	XXII Inter Complement Workshop /Switzerland	2008/Sept	Oral
		CMB Graduate Student retreat/Honolulu	2008/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2007/April	Poster
		CMB Graduate Program Retreat	2005/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2005/April	Poster
Horton, Jaime	PhD 2006	CMB Graduate Student retreat	2008/Aug	Oral
Khemmani, Mark	MS 2007	None
Kim, Courtney	MS 2005
	PhD 2007	Inter AIDS Society /Mexico	2008/Aug	Poster   Oral
		Inter Mitochondria Meeting/MD	2008/Jan	Poster
		Biomedical Sciences Symposium/Honolulu	2007/March	Poster
		Biomedical Sciences Symposium/Honolulu	2006/April	Poster
Linnolt, Michael	PhD 2003	CMB Graduate Program Retreat	2007/Aug	Oral
Loeffler, Jorik	PhD 2007	None
Moikeha, Nickol	MS 2007	Society for Advancement of Chicanos and Native Americans	2007/Oct	Poster
Naeole, Chrystie	PhD 2002	Biomedical Sciences Symposium/ Honolulu	2006/April	Poster
		Albert L. Tester Memorial Symposium	2006/March	Oral/Poster
		Hawaii State Infrastructure Development Network for Biomedical Research Excellence Symposium/Hon	2006	Poster
		St.Jude Children's Research Hospital National Graduate Student Symposium/Tenn	2006	Oral/Poster
		Biomedical Sciences Symposium/Honolulu	2005/April	Poster
		Albert L. Tester Memorial Symposium	2005/March	Oral/Poster
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
		CMB Graduate Program Retreat	2004/May	Oral
		Albert L. Tester Memorial Symp/Honolulu	2004	Poster
		Soc Adv of Chicanos & Native Amer/TX	2004	Poster
		CMB Graduate Program Retreat	2004/May	Oral
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
		Soc Adv of Chicanos & Native Amer/NM	2003	Poster
		HI St Biomed Research Infrast Netw Sym/HI	2003	Poster
		Biomedical Sciences Symposium/Honolulu	2003	Poster
		Albert L. Tester Memorial Symposium/Honolulu	2002	Poster
Pang, Xiaosha	PhD 2006	None
Pitts, Matthew	PhD 2004	CMB Graduate Student Retreat/Honolulu	2008/Aug	Oral
		CMB Graduate Program Retreat	2007/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2007/March	Poster
		Biomedical Sciences Symposium/Honolulu	2006/April	Poster
		Biomedical Sciences Symposium/Honolulu	2005/April	Poster
		CMB Graduate Program Retreat	2005/Aug	Oral
Raman, Arjun	PhD 2007	None
Reeves, Mariclair	PhD 2007	CMB Graduate Student retreat/Honolulu	2008/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2007/Mar	Poster
Seki, Jennifer	MS  2004	Biomedical Sciences Symposium/Honolulu	2005/April	Poster
Sharma, Amrish	PhD 2006	None
Squires, Jeffrey	PhD 2003	CMB Graduate Student Retreat	2007/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2007/Mar	Poster
		Biomedical Sciences Symposium/Honolulu	2006/April	Poster
		CMB Graduate Student retreat	2005/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2005/April	Poster
Takeuchi, Kenneth	PhD 2002	CMB Graduate Program Retreat	2007/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2006/April	Poster
		CMB Graduate Program Retreat	2004/May	Oral
		Biomedical Symposium/Honolulu	2004/April	Poster
Teeters, Kelsa	PhD 2004	American Thorasic Society	2007	Poster
		CMB Graduate Program Retreat	2007/Aug	Oral
		Biomedical Sciences Symposium/Honolulu	2007/March	Poster
		Biomedical Sciences Symposium/Honolulu	2006/April	Poster
		American Thorasic Society/San Diego	2005/May	Poster
Wong, Mayee	PhD 2004	CMB Graduate Program Retreat	2005/Aug	Oral
		Tropical Medicine Conference/Honolulu	2005/April	Poster
		EWC Emerging Infectious Diseases
Young-Robbins, Shirley	MS 2005	CMB Graduate Program Retreat	2006	Oral

                Publications are summarized in the table below for current students. 

Publications of Research Completed by Current Students
Name (Years in Training)	Publication (Authors, Year,Title, Journal)
Agsalda, Melissa (2005-present)	Kusao I, Agsada M, Troelstrup D, Villanueva N, Shiramizu   B(2008) Chemotoxicity recovery of mitochondria In non-Hodgkin lymphoma resulting in minimal residual disease. Pediatric Blood and Cancer 51:193-7.
Archer, Crystal (2006-present)	Groll, Michael, Schellenberg B, Bachmann A, Archer, Crystal R, Huber R, Powell TK, Lindow S, Kaiser M, Dudler (2008) A Plant Pathogen Virulence Factor Inhibits the Eukaryotic Proteasome by a novel Mechanism. Nature. April Vol 452: 755-759
Barnhill, Jason (2006-present)	Barnhill JC, Stokes AJ, Koblan-Huberson M, Shimoda LM, Muraguchi A, Adra CN, Turner H.(2004) RGA protein associates with a TRVP ion Channel during Biosynthesis and trafficking. J Cel Biochem. 2004 Mar 1;91(4):808-20
Campora, Cara (2004-present)	Campora, CE and Hokama Y(2008)Marine toxins: seafood safety and detection methods.  Handbook of Seafood and Seafood Products Analysis.  CRC Press      Campora CE, Hokama Y, Yabusaki K, Isobe M(2007)Development and validation of an enzyme-linked immunosorbent assay(ELISA) for the detection of ciguatoxin using chicken immunoglobulin Y as an analytic tool.  Journal of Clinical Laboratory Amalysis.      Campora CE, Hokama Y, JSM Ebesu(2006) Comparative Analysis of purified Pacific and Caribbean Ciguatoxin Congeners and Related Marine Toxins Using Modified ELISA Technique. Journal of Laboratory Analysis 20:121-125.      Hokama Y, Chun KE, Campora,CE, Higa N, Suma C, Hamajima A, Isober M(2006) Biological Activity of the Functional Epitope of Ciguatoxin Fragment AB on the Neuroblastoma sodium channel in tissue culture.
Cochrane, K (2002-present)	Lendvay TS, Sweet R, Han CH, Soygur T, Cheng JF, Plaire JC, Charleston JS, Charleston LB, Bagai S, Cochrane K, Rubio E, Bassuk JA.(2007) Compensatory Paracrine Mechanisms that Define the Urothelial response to Injury in Partial Bladder Outlet Obstruction. Am J Physiol Renal Physiol. 200-7 Jul 3      Bassuk, JA, Cochrane K Mitchell ME (2004) Induction of Urothelial Cell Proliferation by Fibroblast Growth Factor-7 in RAG1-Deficient Mice. Bladder Disease: Research Concepts and Clinical Applications. Kluwer Academic/Plenum Press.       Bassuk JA, Cochrane K, Mitchell ME(2003) Induction of urothelial Cell Proliferation by Fibroblast growth factor -7 in RAG-1-deficient mice. Adv Exp Med Biol. 2003;539(PtB):623-33.
Coussens, MJ (2004-present)	Narala SR, Allsopp RC, Wells TB, Zhang G, Prasad P, Coussens MJ, Rossi DJ, Weissman IL, Vaziri H(2008) SIRT1acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity. Mol Cell Biol 19, 1210-9.      Coussens M, Maresh G, Yanagimachi R, Maeda G, Allsopp R(2008) Spermatogenesis and Germ Cell Function. PLoS ONE. 3(2): e1571      Coussens M,Moisyadi S, Suganuma R, Yanagimachi R, Allsopp R(2006)Regulation and effects of modulation of telomerase reverse transcriptase expression in primordial germ cells during development. Biolo Reproduc. 2—6 Nov; 75(5):785-91.      Coussens PM, Coussens MJ, Tooker BC, Nobis W (2004) Structure of the bovine natural resistance associated macrophage protein (NRAMP1)gene and identification of a novel polymorphism. DNASeq. 15(1):15-25.      Coussens, PM, Tooker B, Nobis W, Coussens MJ (2001) Genetics Characterization of the NRAMP1 Gene.  Research Forum 2001, Michigan State University, East Lansing, MI.      Coussens PM, Tooker BC, Nobis W, Coussens MJ. (2001) Genetics and Genomics of Susceptibility to Mycobacterial Infection in Cattle. Initiative for Future Agriculture and Food Systems 2001.
Diller, Karl (2005-present)     Hew, B (2002-present)	4 Books, over 60 articles      Diller, Karl(2007) chapter in a fully references book. Cradle of Language. Oxford University Press.             Fritzinger, DC, Hew BE, Thorne M, Pangburn MK, Janssen BJ, Gros P, Vogel C-W(2008) Human C3 Derivatives with Cobra Venom Factor-like functions for therapeutic complement Depletion. Dev Comp Immunol Accepted for publication.      Fritzinger DC, Hew BE, Thorne M, Vogel CW (2004) Functional Characterization of cobra venom factor/cobra C3 hybrid proteins. Mol. Immunol. 41, 23      Hew BE, Thorne M, Fritzinger DC, Vogel CW (2004)Humanized cobra venom factor (CVF): Generation of Human C3 derivatives with CVF-like function.  Mol Immunol. 41,244      Kock MA, Hew BE, Bammert H, Fritzinger DC, Vogel CW (2004) Structure and function of recombinant Cobra Venom Factor. J Biol Chem. 279, 30836-30843.      Vogel CW, Fritzinger DC, Hew BE, Thorne M (2004) Generation of “humanized cobra venom factor” for therapeutic complement depletion. Third International Conference on Innate Immunity. Crete, Greece.      Vogel CW, Fritzinger DC, Hew BE, Thorne M, Bammert, H (2004) recombinant cobra venom factor. Mol Immunol. 41, 91-199.      Fritzinger DC, Hew BE, Wehrhahn D, Vogel CW (2003) Functional Characterization of Cobra Venom Factor/Cobra C3 Hybrid Protein. Mol Immunol. 40, 199.
Horton(Lachmann), Jaime (2005-present)	Sapra R, Gaucher SDP, Lachmann JS, Buffleben GM, Chirica GS, Comer JE, Peterson JW, Chopra AK, Singh AK(2006) Proteomic analyses of murine macrophanges treated with Bacillus anthracis lethal toxin. Microb Pathog. Oct-Nov; 41(4-5): 157-67.      Chirica G, Lachmann J, Chan J(2006) Size exclusion chromatography of microliter volumes  for on-line use in low-pressure microfluidic systems. Anal Chem. 2006 Aug 1;78(15):5362-8.
Khemmani, Mark     (2007-present)	None
Naeole, CKM (2002-present)	Naeole CKM and Haymer D. (2003) Use of oligonucleotide arrays for molecular taxonomic studies of closely related species in the oriental fruit fly (Bactrocera dorsalis) complex. Molecular Ecology Notes 3: 662-665.
Seki, Jennifer (2004-present)	Wallick CJ, Gamper I,  Gamper, I, Thorne M, Feith DJ, Takasaki K, Wilson SM, Seiki JA, Pegg, AE, Byus, C, Bachmann, AS (2005) Key role for p27-Kip-1 retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest  in MYCN-amplified human neuroblastoma cells. Oncogene. 24: 5606-5618
Squires, JE (2003-present)	Squires JE, Sun J, Caffrey JL, Yoshishige D, Mallet RT. (2003) Acetoacetate augments beta-adrenergic inotropism of stunned myocardium by an antioxidant mechanism. Am J Physiol Heart Circ Physiol. 284:H1340-7      Mutsvangwa T, Gilmore J, Squires JE, Lindinger MI, McBride BW. (2004) Chronic metabolic acidosis increases mRNA levels for components of the ubiquitin-mediated proteolytic pathway in skeletal muscle of dairy cows. J Nutr. 134:558-61.
Takeuchi, KK (2002-present)	Kanemaru KK, Tuthill MC, Takeuchi KK, Sidell N, Wada RK(2007) Retinoic acid induced downregulation of MYCN is not mediated through changes in Spl/Sp3.      Tuthill MC, Wada RK, Arimoto JM, Sugino CN, Kanemaru KK, Takeuchi KK, Sidell N.(2003)  N-myc oncogene expression in neuroblastoma is driven by Sp1 and Sp3.  Mol Genet Metab 80:272-280, 2003.
Tarnay(Cogbill), J (2001-present)	Tarnay, J.   Tarnay JN, F. Szeri, A. Iliás, T. Annilo, C. Sung, O. Le Saux, A. Váradi, M. Dean, C.D. Boyd, and S. Robinow (2004). The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.  Insect Molecular Biology Oct;13(5):539-4
Teeters, Kelsa (2004-present)	Jourdan-LeSaux, Teeters K, Orozco C, Stauder S, Tam EK(2004) Effects of IL-4, IL-13, and TGFB2 on human lung fibroblasts. Amer Journal of Respiratory Cell and Molec Biology
Young-Robbins, SS (2005-present)	Borthakur PB, Orozco CC, Young-Robbins SS, Haselkorn R, Callahan SM. (2005) Inactivation of patS and hetN causes lethal levels of heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. 7120 Mol Microbiol. 57:111-23.

 

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