BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Pacific/Honolulu X-WR-TIMEZONE:Pacific/Honolulu BEGIN:VEVENT UID:452@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20251203T120000 DTEND;TZID=Pacific/Honolulu:20251203T130000 DTSTAMP:20251202T021954Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarchara cterizing-toxoplasmosis-toxoplasma-gondii-in-people-and-animals-in-hawaii SUMMARY:TRMD 690 Seminar:"Characterizing Toxoplasmosis (Toxoplasma gondii) in People and Animals in Hawaii" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/89646408152?pwd=52N4SEywaoHlQP20pP1vNeWkbJWDkH.1\nMeeting ID: 896 4640 8 152\nPasscode: 557826\n\nJerrisa Ching Choe\, DVM\, MPH\nPh.D. Student\nDe partment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJoh n A. Burns School of Medicine\, University of Hawaii at Manoa\nToxoplasmos is is a zoonotic parasitic disease caused by Toxoplasma gondii\, which imp acts many species\, including humans\, worldwide. In Hawaii\, toxoplasmosi s causes high morbidity and mortality in marine wildlife populations. In a ddition\, there are a number of cases of human toxoplasmosis reported in t he state each year. While there is evidence of toxoplasmosis present in an imals and people\, the current seroprevalence\, major risk factors\, and g enotypic characteristics of human toxoplasmosis in Hawaii is unknown. The proposed study aims to characterize toxoplasmosis in human and feline popu lations in Hawaii. Overall\, the findings of the study will provide inform ation for health professionals\, communities\, government agencies\, and o ther stakeholders to make informed decisions for disease monitoring\, prev ention programs\, and education to combat the burden of toxoplasmosis in H awaii . CATEGORIES:Seminar LOCATION:Medical Education Building Room 315\, John A. Burns School of Medi cine\,651\, Ilalo Street\, \, Honolulu\,\, Hawaii\, 96813\, United States GEO:21.2965022;-157.86368019999998 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=John A. Burns School of Med icine\,651\, Ilalo Street\, \, Honolulu\,\, Hawaii\, 96813\, United States ;X-APPLE-RADIUS=100;X-TITLE=Medical Education Building Room 315:geo:21.296 5022,-157.86368019999998 END:VEVENT BEGIN:VEVENT UID:451@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20251001T120000 DTEND;TZID=Pacific/Honolulu:20251001T130000 DTSTAMP:20250924T233514Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarhuman -vs-mosquito-linking-behavior-contact-dynamics-and-dengue-virus-evolution- in-a-multidisciplinary-framework SUMMARY:TRMD 690 Seminar:"Human vs. Mosquito: Linking Behavior\, Contact Dy namics\, and Dengue Virus Evolution in a Multidisciplinary Framework" DESCRIPTION:\nZoom Only\nZoom Link: https://us02web.zoom.us/j/89646408152?p wd=52N4SEywaoHlQP20pP1vNeWkbJWDkH.1\nMeeting ID: 896 4640 8152\nPasscode: 557826\n\nPanpim Thongsripong\, Ph.D.\nAssistant Professor Florida Medical Entomology Laboratory and Department of Entomology and Nematology Institu te of Food and Agricultural Sciences University of Florida\nUnderstanding dengue transmission requires examining both human and mosquito behavior\, as well as the evolutionary dynamics of the virus. In this talk\, I presen t a multidisciplinary framework that links behavior\, contact dynamics\, a nd dengue virus evolution. First\, I discuss results from the Bite Diary s urvey\, a citizen science tool that quantifies human–mosquito contact ra tes and identifies behavioral drivers of exposure. I then highlight labora tory studies that measure mosquito blood-feeding rates and the environment al and physiological factors shaping this critical trait. Finally\, I expl ore phylogenomic analyses of dengue virus to uncover lineage turnover even ts and genetic determinants of viral persistence. Together\, these studies demonstrate how integrating human behavior\, mosquito biology\, and viral evolution can advance understanding of dengue transmission risk. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:450@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250917T120000 DTEND;TZID=Pacific/Honolulu:20250917T130000 DTSTAMP:20250913T000550Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarprovi ding-decentralized-and-integrated-hepatitis-c-care-among-hiv-hcv-co-infect ed-patients-in-a-hiv-clinic-in-myanmar SUMMARY:TRMD 690 Seminar:"Providing decentralized and integrated hepatitis C care among HIV/HCV co-infected patients in a HIV clinic in Myanmar" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/89646408152?pwd=52N4SEywaoHlQP20pP1vNeWkbJWDkH.1\nMeeting ID: 896 4640 8 152\nPasscode: 557826\n\nDerek Johnson\, MPH\, PhD\nAssistant Professor\, Epidemiologist\, Office of Public Health Sciences University of Hawaii at Manoa\nMyanmar has one of the highest HIV prevalence rates in Southeast As ia\, with approximately 6% of sex workers and 35% of injection drug users testing positive for HIV. Hepatitis C virus (HCV) co-infection among peopl e living with HIV (PLHIV) is also a significant public health concern\, wi th HCV prevalence estimated to be between 10–20% for PLHIV\, and approxi mately 56% of injection drug users testing positive for HCV. In low-income settings like Myanmar\, access to HCV diagnosis and treatment remains lim ited due to centralized healthcare models\, financial constraints\, and lo gistical barriers. Our research evaluated a decentralized\, integrated mod el of hepatitis C care for HIV/HCV co-infected patients within an HIV clin ic in Myanmar. By providing point-of-care testing\, simplified diagnostics \, and direct-acting antiviral (DAA) treatment onsite\, our project aimed to reduce patient attrition and improve treatment uptake and outcomes. Dec entralized healthcare is vital in resource-limited settings as it enhances service accessibility\, reduces patient costs\, and strengthens linkage t o care. Our integrated care model demonstrated high treatment initiation a nd sustained virologic response (SVR) rates\, supporting the scalability a nd relevance of our project for similar low-resource contexts burdened by co-infections. CATEGORIES:Seminar LOCATION:MEB 301\, John A Burns School of Medicine\, 651 Ilalo St.\, Honolu lu\, HI\, 96813\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=MEB 301\, John A Bur ns School of Medicine:geo:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:449@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250507T120000 DTEND;TZID=Pacific/Honolulu:20250507T130000 DTSTAMP:20250501T002520Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarinves tigation-of-a-safe-and-scalable-expression-platform-for-the-production-of- recombinant-influenza-neuraminidase-protein SUMMARY:TRMD 690 Seminar:"Investigation of a Safe and Scalable Expression P latform for the Production of Recombinant Influenza Neuraminidase Protein" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/81853192041?pwd=DlS9NR8Q7JLSk7wgYACVanVFiTtcnz.1\nMeeting ID: 818 5319 2 041\nPasscode: 563519\n\n(Andy) Qigui Yu\, Ph.D.\nProfessor of Microbiolog y and Immunology\,\nIndiana University School of Medicine\, Indianapolis\, Indiana\nImmune checkpoints (ICPs) are essential regulators of the immune system\, critical for immune surveillance\, defense\, regulation\, and se lf-tolerance. Our research shows that soluble ICPs are dysregulated in the periphery across multiple human diseases\, including AIDS\, COVID-19\, al cohol use disorder\, and sickle cell disease\, highlighting their potentia l as non-invasive biomarkers and indicators of therapeutic efficacy. In th e central nervous system (CNS)\, we have identified dynamic regulation of ICPs in response to injury and infection. Using a traumatic brain injury ( TBI) model\, we recently demonstrated that PD-L1\, a key inhibitory ICP\, is robustly and transiently induced in reactive astrocytes\, which act as neuroimmune and neuroinflammatory gatekeepers. In neuroHIV\, both soluble and membrane-bound ICPs are dysregulated in the CNS\, correlating with neu roimmune activation\, inflammation\, and clinical manifestations of the di sease. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:444@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250506T110000 DTEND;TZID=Pacific/Honolulu:20250506T120000 DTSTAMP:20250430T191040Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-seminaradvancing -detection-and-immunological-insights-in-alphavirus-infections SUMMARY:TRMD Seminar:"Advancing Detection and Immunological Insights in Alp havirus Infections" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/88548800286?pwd=ZRG7ZjFZcIaJU8C7NP5SSIykk28IAQ.1\nMeeting ID: 885 4880 0 286\nPasscode: 973983\n\nBobby Brooke Herrera\, Ph.D.\nAssistant Professor \, Rutgers Global Health Institute\nAssistant Professor\, Department of Me dicine\, Rutgers Robert Wood Johnson Medical School\nResearch Scientist\, Child Health Institute of New Jersey\nDr. Bobby Brooke Herrera earned his Ph.D. in Biological Sciences in Public Health from Harvard University in 2 018. Following his postdoctoral training at Harvard Medical School\, he co -founded E25Bio\, Inc. at MIT’s The Engine\, where he led a team focused on developing rapid diagnostics for dengue\, Zika\, and SARS-CoV-2. Under his leadership\, the company secured over $8 million in funding from the NIH\, the Bill &\; Melinda Gates Foundation\, and private investors. In recognition of his work\, Dr. Herrera was named to the Forbes 30 Under 30 list in Healthcare in 2020. He joined the faculty at Rutgers Robert Wood Johnson Medical School in 2022.\nDr. Herrera’s lab investigates arthrito genic alphaviruses—including chikungunya\, o’nyong-nyong\, and Mayaro viruses—which cause debilitating joint disease but remain underdiagnosed and immunologically understudied. His team has developed RT-RPA–based r apid molecular diagnostics for all three viruses\, enabling both point-of- care detection and sequencing for molecular surveillance. Concurrently\, h is lab is exploring how T cells drive virus-induced arthritis\, with emerg ing data highlighting a role for CXCR3–CXCL10 signaling in T cell recrui tment to inflamed joints. By integrating molecular diagnostics with studie s of T cell–mediated immunopathogenesis\, his work aims to advance both outbreak preparedness and therapeutic strategies for neglected tropical di seases. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:443@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250505T110000 DTEND;TZID=Pacific/Honolulu:20250505T120000 DTSTAMP:20250430T015534Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=thesis-defensenovel-a ntiviral-drug-targets-for-screening-potential-fda-approved-compounds-to-co unter-flavivirus-infection SUMMARY:Thesis Defense:"Novel Antiviral Drug Targets for Screening Potentia l FDA-approved Compounds to Counter Flavivirus Infection" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/86470100527?pwd=yNErmgC9W8vLGFGhrrokqBC097ihr5.1\nMeeting ID: 864 7010 0 527\nPasscode: 655133\n\nJaymie Bilog-Mina\nM.S. Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns S chool of Medicine\, University of Hawaii at Manoa\nDengue (DENV) and West Nile viruses (WNV) are major global health concerns\, with WNV prevalent i n the U.S. and DENV occasionally detected in Hawaii. Currently\, no effect ive antiviral treatments exist for flavivirus infections\, highlighting th e need for new drug targets. NS3\, a key enzyme in viral replication\, mus t localize to the replication organelle (RO)\, composed of convoluted memb ranes (CMs) and vesicle packets (VPs). This study explores the role of NS4 A and NS4B in facilitating NS3's movement within the RO using high-resolut ion confocal microscopy (HRCM). HEK293 cells were co-transfected with NS3 and different forms of NS4A/NS4B (NS4AB\, NS4A\, NS4B) and triple-transfec ted with Sec61β-RFP\, an ER marker\, under WNV-infected and uninfected co nditions. Additionally\, the contribution of NS1 was assessed by transfect ing HEK-293 cells with Sec61β-RFP\, NS1 in its non-permeabilized and perm eabilized forms\, and either NS3 or different forms of NS4A/NS4B. Confocal imaging and Pearson Correlation Coefficient (PCC) analysis demonstrated t hat NS3 localizes to the foci (RO) when viral structures appear as fluores cent aggregates\, indicating a random recruitment event during RO formatio n. In infected cells\, NS3 was additionally recruited to the rough endopla smic reticulum (RER) before reaching the RO\, suggesting that other viral proteins play a role in its translocation. In the presence of NS1\, some o f the NS3 is visualized in the ER and the foci in both non-permeabilized a nd permeabilized conditions\, indicating NS1 plays a role in stabilizing N S3 in the RO. These findings suggest two possible mechanisms for NS3 recru itment: (1) random encapsulation during RO formation and (2) a sequential process requiring additional viral factors\, involving NS2B and possibly N S1. Understanding these interactions may help identify new antiviral drug targets for the further development of safe and effective antiviral therap ies. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:447@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250501T120000 DTEND;TZID=Pacific/Honolulu:20250501T130000 DTSTAMP:20250430T192356Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=zoom-only-for-faculty -pediatric-resident-lecture-antimicrobial-therapy SUMMARY:Zoom only for faculty - Pediatric Resident Lecture: “Antimicrobia l Therapy” DESCRIPTION:\nBy Zoom\nRegister in advance for this meeting: https://us02we b.zoom.us/meeting/register/NAy4476zR9uDrcN3z27zPQ\nAfter registering\, you will receive a confirmation email containing information about joining th e meeting\n\nDr. Jason Newland\nDr. Jason Newland is a Professor of Pediat rics and the Henry G. Cramblett Endowed Chair in Medicine at The Ohio Stat e University College of Medicine. He is also the Division Chief\, Infectio us Diseases\, Department of Pediatrics at Nationwide Children's Hospital. He will be the Visiting Professor in the Department of Pediatrics\, UH JAB SOM from April 30 to May 1\, 2025. Attached is the flyer with his presenta tions.\n\nDr. Newland is the founder and leader of SHARPS (Sharing Antimic robial Reports for Pediatric Stewardship) Collaborative that has promoted antimicrobial stewardship initiatives across pediatric programs and hospit als nationally and internationally. He is the program organizer of the Ann ual International Pediatric Antimicrobial Stewardship Conference. He has h eld several grants for the research of antimicrobial utilization\, resista nce and stewardship initiatives. In addition\, he has been an invited spea ker locally\, nationally and internationally\, trained and mentored many f ellows\, residents and students. He is currently the Vice-Chair of the Pre sidential Advisory Council on Combating Antibiotic-Resistant Bacteria and member of the Emerging Infection Network Executive Committee. He is active in the Pediatric ID Society serving on the Board of Directors CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:446@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250501T080000 DTEND;TZID=Pacific/Honolulu:20250501T090000 DTSTAMP:20250430T192114Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pediatric-grand-round s-antimicrobial-stewardship-everyones-responsibility SUMMARY:Pediatric Grand Rounds: “Antimicrobial Stewardship: Everyone’s Responsibility” DESCRIPTION:\nIn Person &\; By Zoom\nRegister in advance for this webina r:\nhttps://hph-org.zoom.us/webinar/register/WN_dHvSvOfXTX2hDRABXj8u5Q\nAf ter registering\, you will receive a confirmation email containing informa tion about joining the webinar\n\nDr. Jason Newland\nDr. Jason Newland is a Professor of Pediatrics and the Henry G. Cramblett Endowed Chair in Medi cine at The Ohio State University College of Medicine. He is also the Divi sion Chief\, Infectious Diseases\, Department of Pediatrics at Nationwide Children's Hospital. He will be the Visiting Professor in the Department o f Pediatrics\, UH JABSOM from April 30 to May 1\, 2025. Attached is the fl yer with his presentations.\n\nDr. Newland is the founder and leader of SH ARPS (Sharing Antimicrobial Reports for Pediatric Stewardship) Collaborati ve that has promoted antimicrobial stewardship initiatives across pediatri c programs and hospitals nationally and internationally. He is the program organizer of the Annual International Pediatric Antimicrobial Stewardship Conference. He has held several grants for the research of antimicrobial utilization\, resistance and stewardship initiatives. In addition\, he has been an invited speaker locally\, nationally and internationally\, traine d and mentored many fellows\, residents and students. He is currently the Vice-Chair of the Presidential Advisory Council on Combating Antibiotic-Re sistant Bacteria and member of the Emerging Infection Network Executive Co mmittee. He is active in the Pediatric ID Society serving on the Board of Directors CATEGORIES:Seminar LOCATION:KMCWC Nan Auditorium - 2nd Floor Diamond Head Tower\, 1319 Punahou St.\, Honolulu\, HI\, 96826\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1319 Punahou St.\, Honolulu \, HI\, 96826\, United States;X-APPLE-RADIUS=100;X-TITLE=KMCWC Nan Auditor ium - 2nd Floor Diamond Head Tower:geo:0,0 END:VEVENT BEGIN:VEVENT UID:445@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250430T123000 DTEND;TZID=Pacific/Honolulu:20250430T133000 DTSTAMP:20250430T191832Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=professor-rounds-impl ementation-science-based-infectious-diseases-research SUMMARY:Professor Rounds: “Implementation Science Based Infectious Diseas es Research” DESCRIPTION:\nIn Person &\; By Zoom\nRegister in advance for this meetin g: https://us02web.zoom.us/meeting/register/pTysKn3MQhqvdT4xwm_plw\nAfter registering\, you will receive a confirmation email containing information about joining the meeting.\n\nDr. Jason Newland\nDr. Jason Newland is a P rofessor of Pediatrics and the Henry G. Cramblett Endowed Chair in Medicin e at The Ohio State University College of Medicine. He is also the Divisio n Chief\, Infectious Diseases\, Department of Pediatrics at Nationwide Chi ldren's Hospital. He will be the Visiting Professor in the Department of P ediatrics\, UH JABSOM from April 30 to May 1\, 2025. Attached is the flyer with his presentations.\n\nDr. Newland is the founder and leader of SHARP S (Sharing Antimicrobial Reports for Pediatric Stewardship) Collaborative that has promoted antimicrobial stewardship initiatives across pediatric p rograms and hospitals nationally and internationally. He is the program or ganizer of the Annual International Pediatric Antimicrobial Stewardship Co nference. He has held several grants for the research of antimicrobial uti lization\, resistance and stewardship initiatives. In addition\, he has be en an invited speaker locally\, nationally and internationally\, trained a nd mentored many fellows\, residents and students. He is currently the Vic e-Chair of the Presidential Advisory Council on Combating Antibiotic-Resis tant Bacteria and member of the Emerging Infection Network Executive Commi ttee. He is active in the Pediatric ID Society serving on the Board of Dir ectors CATEGORIES:Seminar LOCATION:KMCWC Diamond Head Tower - Conf Rooms 9-10\, 1319 Punahou St.\, Ho nolulu\, HI\, 96826\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1319 Punahou St.\, Honolulu \, HI\, 96826\, United States;X-APPLE-RADIUS=100;X-TITLE=KMCWC Diamond Hea d Tower - Conf Rooms 9-10:geo:0,0 END:VEVENT BEGIN:VEVENT UID:441@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250430T120000 DTEND;TZID=Pacific/Honolulu:20250430T130000 DTSTAMP:20250424T210940Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarthe-p otential-of-geographic-information-system-for-one-health-approach-mapping- zoonotic-and-vector-borne-transmissions-hotspots-and-improving-public-heal th-strategies-2 SUMMARY:TRMD 690 Seminar:"Investigation of a Safe and Scalable Expression P latform for the Production of Recombinant Influenza Neuraminidase Protein" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/81853192041?pwd=DlS9NR8Q7JLSk7wgYACVanVFiTtcnz.1\nMeeting ID: 818 5319 2 041\nPasscode: 563519\n\nMary Kay McLean\nPh.D. Student\nDepartment of Tro pical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Scho ol of Medicine\, University of Hawaii at Manoa\nAccording to the World Hea lth Organization\, there are around a billion cases of seasonal influenza annually with 3-5 million cases of severe illness resulting in 290\,000 to 650\,000 deaths. Current influenza vaccinations target the more abundant hemagglutinin surface protein and have shown to be suboptimal in preventin g disease due to the high mutation rate of circulating virus throughout th e year. Studies have demonstrated that Neuraminidase (NA)\, the second mos t abundant influenza surface protein\, may be a more effective target due to its slower evolution rate compared to HA and its similarities across st rains. Attempts at producing a stable recombinant NA protein in the labora tory setting have been met with challenges. There are promising results ut ilizing a Measles virus phosphoprotein to ensure the intermolecular tetram er formation required for production of stable and enzymatically active NA is maintained. To date\, the production of this NA globular head stabiliz ed by the Measles virus phosphoprotein tetramerization domain (N1-MPP) for the use as vaccine antigen has been performed utilizing the baculovirus e xpression system. This study aims to utilize the Drosophila S2 expression system to grow high concentrations of protein in suspension cultures allow ing scaling up and maximizing yield. The use of this system to generate N1 -MPP could aid in quick and sustainable production of this candidate vacci ne antigen. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:442@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250428T100000 DTEND;TZID=Pacific/Honolulu:20250428T110000 DTSTAMP:20250424T210553Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=thesis-defenseingenui ty-pathway-analysis-of-biomarkers-and-immune-mediators-of-kawasaki-disease SUMMARY:Thesis Defense:"Ingenuity Pathway Analysis of Biomarkers and Immune Mediators of Kawasaki Disease" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://zoom.us/j/939161 89831?pwd=1VamRSxgxgeQQvTKvRvL5hbILRRGMl.1\nMeeting ID: 846 6076 7443\nPas scode: 274922\n\nTatiana Aguilar\nM.S. Candidate\nDepartment of Tropical M edicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of M edicine\, University of Hawaii at Manoa\nKawasaki Disease (KD) is an acute systemic vasculitis of unknown etiology affecting children under the age of five globally. As the risk of coronary artery abnormalities (CAA) and r esistance to intravenous immunoglobulin (IVIG) treatment remain significan t challenges in patients who develop KD\, it is imperative to identify con tributing factors. Ingenuity Pathway Analysis (IPA) allows for the discove ry of the biological context behind genomic\, transcriptomic\, proteomic a nd metabolomic data. We investigated the acute\, subacute\, and convalesce nt phases of clinically characterized KD patient samples to understand the progression of KD\, formation of CAA and resistance to IVIG. We employed IPA to identify the pathways and functions associated with immune cell rec ruitment\, vascular permeability\, tissue remodeling\, and dysregulation o f the NF-kB pathway. Our study suggests 15 biomarkers for the differential diagnosis of acute KD. We further add to the existing knowledge of the pa thogenesis behind CAA formation through the immune response within this su bset of patient samples and mechanisms of IVIG resistance. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:440@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250416T120000 DTEND;TZID=Pacific/Honolulu:20250416T130000 DTSTAMP:20250414T202748Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarthe-p otential-of-geographic-information-system-for-one-health-approach-mapping- zoonotic-and-vector-borne-transmissions-hotspots-and-improving-public-heal th-strategies SUMMARY:TRMD 690 Seminar:"The Potential of Geographic Information System fo r One Health Approach: Mapping Zoonotic and Vector-Borne Transmissions Hot spots and Improving Public Health Strategies" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/81853192041?pwd=DlS9NR8Q7JLSk7wgYACVanVFiTtcnz.1\nMeeting ID: 818 5319 2 041\nPasscode: 563519\n\nRodson Zorilla\nPh.D. Student\nDepartment of Trop ical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Schoo l of Medicine\, University of Hawaii at Manoa\nThe unique geography and bi odiversity of Hawaii is conducive to the transmission of zoonoses and vect or-borne diseases in humans\, animals\, and their shared environment. Some of these diseases are endemic in Hawaii\, which has resulted in to multip le outbreaks on different Hawaiian Islands. Effective prevention and mitig ation of disease transmission rely on a comprehensive One Health approach addressing environmental and socioeconomic factors that exacerbate the tra nsmission of zoonotic and vector-borne pathogens. However\, implementation of One Health is often impeded by institutional silos\, lack of awareness and understanding of zoonoses and vector-borne diseases\, and insufficien t intersectoral collaboration and coordination. Geographic information sys tem (GIS) tools are used to create\, analyze\, and share interactive web m aps from various sources. It can process data to identify trends and corre lations and perform hotspots and suitability analyses of potential outbrea ks of diseases. I will present how GIS can be applied in One Health approa ch to address zoonoses and vector-borne diseases endemic in Hawaii. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:439@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250402T120000 DTEND;TZID=Pacific/Honolulu:20250402T130000 DTSTAMP:20250401T221548Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarinves tigating-the-role-of-vaccine-induced-humoral-immune-responses-in-protectio n-against-marburg-virus-disease SUMMARY:[ZOOM] TRMD 690 Seminar:"Investigating the Role of Vaccine Induced Humoral Immune Responses in Protection against Marburg Virus Disease" DESCRIPTION:\nBy Zoom Only\nZoom Link: https://us02web.zoom.us/j/8185319204 1?pwd=DlS9NR8Q7JLSk7wgYACVanVFiTtcnz.1\nMeeting ID: 818 5319 2041\nPasscod e: 563519\n\nTroy Odo\nPh.D. Student\nDepartment of Tropical Medicine\, Me dical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, Un iversity of Hawaii at Manoa\nFiloviruses cause severe disease in humans an d different members of the family have led to outbreaks in humans. Current ly\, two vaccines have been approved to protect against Ebola virus (EBOV) infection\, but there are no vaccines licensed to protect against any oth er filoviruses. Specifically\, Marburg virus (MARV) has demonstrated the c apability of causing deadly disease\, including recent outbreaks in Rwanda (2024) and Tanzania (2025). Continued outbreaks and high case fatality ra tes necessitates the need for MARV vaccines. The EBOV glycoprotein (GP) sh ares very limited homology with the MARV glycoproteins which eliminates th e chance for cross-protection of EBOV specific vaccines. Our laboratory ha s developed an adjuvanted recombinant glycoprotein subunit vaccine for MAR V that has previously shown to be fully protective against lethal infectio n in non-human primates. Despite the high efficacy\, the exact mechanisms of protection remain unclear. There are no known correlates of protection against Marburg virus disease (MVD)\, but antibodies are thought to play a vital role in protective efficacy of filovirus vaccines. Our current work aims to further characterize the role of humoral immune responses for pro tection against MVD. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:438@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20250226T120000 DTEND;TZID=Pacific/Honolulu:20250226T130000 DTSTAMP:20250221T222410Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarnovel -antiviral-drug-targets-for-screening-potential-fda-approved-compounds-to- counter-flavivirus-infection SUMMARY:TRMD 690 Seminar:"Novel Antiviral Drug Targets for Screening Potent ial FDA- Approved Compounds to Counter Flavivirus Infection" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/81853192041?pwd=DlS9NR8Q7JLSk7wgYACVanVFiTtcnz.1\nMeeting ID: 818 5319 2 041\nPasscode: 563519\n\nYu-Ching Dai\nPh.D. Student\nDepartment of Tropic al Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\nDengvaxia\, a chimeric yellow fever tetravalent dengue vaccine from Sanofi Pasteur\, is the first licen sed dengue vaccine. Due to the higher risk of severe dengue virus (DENV) d isease found in baseline DENV-naïve recipients\, Dengvaxia is recommended by WHO for baseline DENV-immune individuals only. In 2016\, a Dengvaxia v accination campaign was launched in the Philippines with >\;830\,000 chi ldren receiving at least one dose without prior testing for DENV serostatu s\; thousands of baseline DENV-naïve recipients are under high risk of se vere disease for future infection. We hypothesize that virion maturation s tatus as well as virus interference of Dengvaxia may affect the quality of antibodies induced in DENV-naïve recipients. We previously identified ba seline DENV-naïve and -immune vaccinees from 199 participants of a fever surveillance program at the Research Institute for Tropical Medicine\, Phi lippines. Here\, we further characterized antibody responses among these D engvaxia recipients by examining the binding of antibodies to mature and i mmature virions\, and evaluating the spectrum of type-specific antibodies among baseline DENV-naïve compared with DENV-immune recipients. I will pr esent our preliminary results and future directions to improve our underst anding of immune responses induced by Dengvaxia and future vaccine develop ment. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:436@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20241127T120000 DTEND;TZID=Pacific/Honolulu:20241127T130000 DTSTAMP:20241122T020740Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=7828 SUMMARY:TRMD 690 Seminar:"Novel Antiviral Drug Targets for Screening Potent ial FDA- Approved Compounds to Counter Flavivirus Infection" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://zoom.us/j/927638 52517?pwd=JfNprk9hhRKDx6lrLcpl6RrZHsP32M.1\nMeeting ID: 927 6385 2517\nPas scode: 081153\n\nJaymie Bilog-Mina\nM.S. Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\nDengue (DENV) and West Nile (WN V) pose a significant threat to global health due to their widespread dist ribution and their lack of effective vaccines or antivirals. Identifying p otential antiviral drug targets within the viral multiplication cycle is c rucial for the development of effective antiviral drugs. This research foc uses on targeting NS3 that is critical for viral polyprotein processing an d RNA synthesis. NS3 must be present in the viral replication organelle (R O) to carry out these functions. By utilizing high-resolution confocal mic roscopy (HRCM)\, and biochemical methods\, we aim to demonstrate how NS3 i nteracts with NS4A and NS4B in creating RO environment conducive for NS3 f unction. We then co-expressed NS3 with various forms of NS4A and NS4B (NS4 AB\, NS4A\, NS4B) in HEK293 cells. Analysis of confocal images collected a t 24 hours post expression using the Pearson Correlation Coefficient (PCC) shows that NS3 is effectively drawn to the RO only when these viral struc tures form visible fluorescent aggregates. We are now exploring the potent ial role of NS1 in stabilizing and enzymatically priming NS3. By better un derstanding how these viral proteins interact with each other\, we aim to reveal new targets that could lead to antiviral drug screening. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:435@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20241126T100000 DTEND;TZID=Pacific/Honolulu:20241126T110000 DTSTAMP:20241122T015659Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=dissertation-defenseo ne-health-approach-for-studying-emerging-and-re-emerging-viruses-in-liberi a SUMMARY:Dissertation Defense:"ONE HEALTH APPROACH FOR STUDYING EMERGING AND RE-EMERGING VIRUSES IN LIBERIA" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://zoom.us/j/939161 89831?pwd=1VamRSxgxgeQQvTKvRvL5hbILRRGMl.1\nMeeting ID: 939 1618 9831\nPas scode: 290421\n\nVarney Kamara\nPh.D. Candidate\nDepartment of Tropical Me dicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Me dicine\, University of Hawaii at Manoa\nThe production and use of recombin ant antigens for integrated serosurveys for Lassa Virus (LASV) and other e merging epidemic-prone viruses are crucial to global health efforts in pre venting future outbreaks. LASV causes millions of infections and over 10\, 000 deaths annually\, predominantly in West Africa. The 2014-2015 Ebola Vi rus Disease outbreak in West Africa and the 2022 EVD outbreak in Congo hig hlighted significant challenges in virus surveillance. Traditional enzyme- linked immunosorbent assay systems are time-consuming\, reagent-intensive\ , and necessitate Biosafety Level 4 containment\, which is often unavailab le in Africa. Recombinant antigens can overcome these limitations\, facili tating safer\, more efficient surveillance. \n\nThis dissertation focuses on developing recombinant dengue virus-2 (DENV-2) and West Nile virus (WN V) NS1 antigens and evaluating the performance of LASV and other viral ant igens across species\, including humans\, rodents\, and dogs\, using a Mul tiplex Immuno-assay (MIA). Findings revealed high LASV antibody prevalence in humans\, moderate in rodents\, and low in dogs\, suggesting dogs are n ot ideal sentinels for Lassa fever. The rodent species composition was dom inated by R. rattus. Further\, the coronavirus survey indicated high react ivity to SARS-CoV-2 and its variants\, with unexpectedly high reactivity t o the Omicron (BA5) antigen due to non-specific binding issues. This study underscores the importance of developing recombinant antigens for MIA to conduct seroprevalence studies\, aiding public health efforts in resource- limited settings to prevent future outbreaks. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:432@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20241123T120000 DTEND;TZID=Pacific/Honolulu:20241123T163000 DTSTAMP:20241112T025130Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2024-aloha-pediatric- infectious-disease-conference SUMMARY:2024 Aloha Pediatric Infectious Disease Conference DESCRIPTION:Registration is now open for the 16th Aloha Pediatric Infectiou s Diseases Conference\, to be held Saturday\, Nov. 23\, from noon to 4:30 p.m. at Kapi‘olani Medical Center for Women &\; Children in the Diamo nd Head Tower Auditorium. There is also an option to attend via Zoom. This annual educational event highlights current topics of interest for those caring for pediatric patients. Keynote speaker is David Kimberlin\, MD\, c odirector\, Division of Pediatric Infectious Diseases at the University of Alabama at Birmingham School of Medicine. Dr. Kimberlin will speak about “Recent Developments in the Detection and Management of Congenital Cytom egalovirus Infections.” Other topics include congenital syphilis\, toxop lasmosis\, tuberculosis in Hawai‘i and TORCH infections. There is no reg istration fee because of the generous sponsorship by the Harry C. &\; N ee Chang C. Wong Foundation.\n\nVisit the conference website to register a nd see the latest updates. CATEGORIES:Conference LOCATION:Kapiolani Medical Center for Women & Children\, 1319 Punahou St.\, Honolulu\, HI\, 96826\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1319 Punahou St.\, Honolulu \, HI\, 96826\, United States;X-APPLE-RADIUS=100;X-TITLE=Kapiolani Medical Center for Women & Children:geo:0,0 END:VEVENT BEGIN:VEVENT UID:434@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20241120T120000 DTEND;TZID=Pacific/Honolulu:20241120T130000 DTSTAMP:20241115T005750Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarlong- term-consequence-of-sars-cov-2-on-monocyte-phenotype-in-covid-19-survivors SUMMARY:TRMD 690 Seminar:"Long-term consequence of SARS-CoV-2 on monocyte p henotype in COVID-19 survivors" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://zoom.us/j/927638 52517?pwd=JfNprk9hhRKDx6lrLcpl6RrZHsP32M.1\nMeeting ID: 927 6385 2517\nPas scode: 081153\n\nThomas Ken Awamura\nPh.D. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\nAs the number of COVID-19 survivors amongst the global population continues to rise\, the rates of post-acute sequelae of COVID19 (PASC) have also increased\, emerging as a significant public health concern. Studies have shown that excessive monoc yte activation is involved in the development of a cytokine storm and subs equent acute lung injury induced by SARS-CoV-2 infection. However\, long-t erm consequences of COVID-19 on monocyte dysregulation and its contributio n to PASC development have not been fully explored. To understand the role of monocytes in PASC\, we aim to analyze monocyte immunophenotyping\, tra nscriptomic changes\, and proinflammatory cytokines associated with monocy te activation and lung fibrosis using blood samples collected from healthy individuals\, recovered COVID-19 survivors\, and COVID-19 survivors with pulmonary PASC (PPASC). In this seminar\, I will present preliminary data from IPA of monocyte bulk RNA-seq\, as well as flow cytometry-based protoc ol designed to evaluate monocyte markers involved in activation and traffi cking. Lastly\, I will propose future studies aimed to determine mechanism s underlying monocyte dysregulation associated with PPASC based on these p reliminary findings. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:433@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20241118T100000 DTEND;TZID=Pacific/Honolulu:20241118T110000 DTSTAMP:20241115T005026Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ludwigs-dissertation- defenseadvancing-filovirus-vaccine-development-developing-high-yield-platf orms-to-express-and-purify-marburg-virus-glycoprotein-and-other-vaccine-ta rgets SUMMARY:Dissertation Defense:"Advancing Filovirus Vaccine Development: Deve loping high-yield platforms to express and purify Marburg virus glycoprote in and other vaccine targets" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://us02web.zoom.us/ j/81604526388?pwd=tFhqUE5QWvOMvry3F43WT8TfKVZ1i7.1\nMeeting ID: 816 0452 6 388\nPasscode: 855247\n\nLudwig Mayerlen\nPh.D. Candidate\nDepartment of T ropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Sc hool of Medicine\, University of Hawaii at Manoa\nEffective recombinant pr otein expression is essential in vaccine development and monoclonal antibo dy production. We are currently in late-stage preclinical development of a trivalent filovirus vaccine candidate against the three most pathogenic f iloviruses: Zaire ebolavirus\, Sudan ebolavirus\, and Marburg marburgvirus .\n\nThe first aim focuses on the optimization of the production process t o create pilot-scale quantities of Marburg virus glycoprotein (MARV GP). T o realize this objective\, we have engineered novel expression vectors for the Drosophila S2 expression system and tested integrases and transposons to enhance copy numbers. The design of this system is tailored to enhance the production of high-quality antigens with yields exceeding those previ ously attained.\n\nThe second aim establishes in-house produced antibodies for immunoaffinity chromatography (IAC) to obtain pure vaccine antigens i n native-like conformations.\n\nThe third aim investigates the stability o f our vaccine formulations. It highlights the remarkable thermostability o f our filovirus vaccine candidates\, which is crucial for storage\, distri bution\, and administration in endemic regions. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:431@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20241113T120000 DTEND;TZID=Pacific/Honolulu:20241113T130000 DTSTAMP:20241108T191113Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarkawas aki-disease-diagnostic-and-prognostic-markers-and-treatment-of-coronary-ar tery-lesions SUMMARY:TRMD 690 Seminar:"Kawasaki Disease: Diagnostic and Prognostic Marke rs\, and Treatment of Coronary Artery Lesions" DESCRIPTION:\nZoom Seminar\nZoom Link: https://zoom.us/j/92763852517?pwd=Jf Nprk9hhRKDx6lrLcpl6RrZHsP32M.1\nMeeting ID: 927 6385 2517\nPasscode: 08115 3\n\nLauren Ching\nPh.D. Candidate\nDepartment of Tropical Medicine\, Medi cal Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, Univ ersity of Hawaii at Manoa\nKawasaki disease (KD) is the most common acquir ed heart disease in young children in the developed world. Early diagnosis and treatment are key to avoid the most severe and long-term complication s of KD. Currently there are no laboratory-based tests for the diagnosis a nd prognosis of KD\, or treatments that specifically target the tissue deg radation and vascular remodeling involved in the development of coronary a rtery aneurysms (CAA). In this study\, we characterized the inflammatory a nd vascular markers associated with acute KD\, CAA\, and intravenous gamma globulin (IVIG) resistance in longitudinal samples collected from 116 pat ients. Using the patients’ convalescent samples as self-controls\, we id entified a panel of immune factors and vascular markers that can be used t o support the clinical diagnostic criteria. In acute KD\, pentraxin-3 and neutrophil elastase levels were significantly higher among patients with C AA and IVIG resistance as compared to patients with normal coronary arteri es and responsive to IVIG\, respectively. These findings provide a platfor m for laboratory-based diagnostic and prognostic markers of KD\, CAA\, and IVIG resistance.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:430@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20241106T110000 DTEND;TZID=Pacific/Honolulu:20241106T120000 DTSTAMP:20241101T195328Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarstudy ing-characteristics-of-drosophila-s2-stable-cell-line-generation-for-recom binant-viral-antigen-production SUMMARY:TRMD 690 Seminar:"Studying characteristics of Drosophila S2 stable cell line generation for recombinant viral antigen production" DESCRIPTION:\nIn Person &\; By Zoom\nContact jmeyer8@hawaii.edu for Zoom information\n\nIsabelle E. Yazel Eiser\nPh.D Student\nDepartment of Tropi cal Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\nRecombinant proteins t hat are derived from priority pathogens are critical for public and global health research. They have numerous research and biopharmaceutical applic ations including the use in surveillance of potential outbreaks\, studying immunological responses to infection\, and the development of vaccines an d serological assays. This talk will give important updates on the product ion of Nipah Virus and Crimean-Congo Hemorrhagic Fever Virus antigens as w ell as discuss ongoing research focused on the cell and molecular biology surrounding efficient establishment of high yielding stable cell lines in the Drosophila S2 system. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:429@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240911T120000 DTEND;TZID=Pacific/Honolulu:20240911T130000 DTSTAMP:20240910T064806Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarpost- covid-pulmonary-injury-in-k18-hace2-mice-shows-persistent-neutrophils-and- neutrophil-extracellular-trap-formation-a-potential-therapeutic-target-ste fanos-giannakopoulos-ph SUMMARY:TRMD 690 Seminar:"Post-COVID pulmonary injury in K18-hACE2 mice sho ws persistent neutrophils and neutrophil extracellular trap formation\; a potential therapeutic target"\, Stefanos Giannakopoulos\, Ph.D. DESCRIPTION:\nIn Person &\; By Zoom\nContact jmeyer8@hawaii.edu for Zoom information\n\nStefanos Giannakopoulos\, Ph.D.\nResearch Scientist\nDepar tment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A . Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\nUp to 30 % of COVID-19 survivors develop persistent pulmonary issues\, such as dysp nea and chronic cough collectively known as long COVID. The pathogenesis o f PASC is complex and multifactorial\, with immune dysregulation playing a key role. Neutrophils release DNA to form neutrophil extracellular traps (NET). While NET combat pathogens\, excessive NET formation can drive lung inflammation\, coagulation\, and fibrosis. Elevated serum levels of NET m arkers (CitH3\, cell-free DNA\, MPO-DNA) are linked to severe COVID-19. Im portantly\, PASC individuals show elevated neutrophil counts and activatio n\, correlating with declining lung function. In our study we investigate the role of neutrophils in the acute and post-acute stages of SARS-CoV-2 i nfection leading to the development of novel therapeutics . CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:428@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240529T100000 DTEND;TZID=Pacific/Honolulu:20240529T110000 DTSTAMP:20240518T011532Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-natalie-subia-dysregulation-of-complement-components-associ ated-with-inflammation-and-coagulation-in-virally-suppressed-people-living -with-hiv SUMMARY:Tropical Medicine MS Thesis Defense\, Natalie Subia: ""Dysregulatio n of complement components associated with inflammation and coagulation in virally suppressed people living with HIV" DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://zoom.us/j/999661 28576?pwd=cXo3c3VKYkhPVytGemp4dTZmb2Fudz09\nCall in: (669) 900-6833\nZoom ID: 999 6612 8576\nPasscode: trmd690\n\nNatalie Subia\nM.S. Candidate\nDep artment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\nAltho ugh HIV has become a manageable chronic disease with the introduction of a combination of antiretroviral therapy\, people living with HIV (PLWH) exp erience a high burden of age-related non-AIDS comorbidities (NACMs). PLWH often presents chronic inflammation and immune activation\, which are thou ght to be key contributing factors for NACM development. The complement sy stem is an essential component of the innate immune system that can influe nce HIV infection and replication. Although inappropriate or excessive com plement activation contributes to various steps of an inflammatory respons e\, little attention has been directed to determining its detrimental effe cts on the health conditions in virally suppressed PLWH. In this study\, w e found significant elevated C5a\, but reduced C2 levels in the plasma sam ples from HIV-seropositive (HIV+) individuals\, compared to HIV-seronegati ve (HIV-) individuals\, but C3a and C9 levels were comparable between grou ps. Regardless of HIV-seropositive status\, C2 levels were strongly associ ated with MPO\, protein C\, and ADAMST13\, but C5a levels were associated only with protein C. However\, the association trends ([C2\, C5a\, protein C\, and MPO] and [MPO and ADAMST13]) were more robust in the HIV+ group t han in the HIV- group. Although the percentages and counts of activated pl atelets (CD41+CD62P+ cells) were significantly reduced\, the expression of CD62P on platelets was drastically increased in HIV+ individuals. Lastly\ , the treatment of plasma from HIV+ individuals to human neutrophils enhan ced NETosis. However\, plasma-induced NETosis was reduced\, but non-lytic NET was still observed when platelets were removed. In summary\, our study reports evidence of complement dysregulation associated with inflammation and coagulation in PLWH. In addition\, altered systemic factors and eleva ted platelet activation in PLWH can trigger neutrophil activation and NET formation\, leading to persistent inflammation\, which is known as a major driver for developing NACMs. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:427@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240501T120000 DTEND;TZID=Pacific/Honolulu:20240501T130000 DTSTAMP:20240429T204230Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarcovid -19-disparities-among-non-native-hawaiian-pacific-islanders-chelsea-nichol as-ms-student SUMMARY:TRMD 690 Seminar:”COVID-19 disparities among Non-Native Hawaiian Pacific Islanders"\, Chelsea Nicholas\, MS Student DESCRIPTION:Zoom Seminar\nContact jmeyer8@hawaii.edu for Zoom information.\ n\nChelsea Nicholas\nM.S. Student\n\n\n\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\n \nUniversity of Hawaiʻi at Mānoa\n\n\n\n\n\nThe NIH-funded “Puipuia l e Ola” project\, as part of the Rapid Acceleration in Diagnostics-Unders erved Populations initiative\, aimed to boost COVID-19 testing acceptance among Pacific Islanders (PI) in Hawaii and Guam. This presentation will fo cus on Hawaii participants (N=3195) and factors influencing COVID-19 testi ng knowledge\, attitudes\, and behavioral intent (KAB) among PI. PI resear chers used respondent-driven sampling to engage participants in pre- and p ost-surveys\, alongside COVID-19 education and testing. Pre-post data were analyzed\, revealing that those receiving education were more likely to p lan regular testing and less likely to misconceive negative test results. Participants also showed decreased agreement with various COVID-19 testing barriers. Culturally tailored communication may enhance PI COVID-19 testi ng behaviors in Hawaii\, fostered by this project's extensive community en gagement.\n\n\n\n\n\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:422@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240427T090000 DTEND;TZID=Pacific/Honolulu:20240427T170000 DTSTAMP:20240316T001733Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=registration-open-for -2024-hawaii-asm-spring-meeting SUMMARY:Registration Open for 2024 Hawai‘i ASM Spring Meeting DESCRIPTION:Registration is now open for the Hawai‘i ASM Spring Meeting. The Spring Meeting is a full day session featuring oral and poster present ations by undergraduates\, graduate students\, and post-doctoral researche rs on microbiology\, immunology\, and other related topics.  The event al so features a keynote speaker and ends with an awards ceremony for outstan ding research presentations.  Registration and abstract submission inform ation:\nStudent Registration\nGeneral Registration\nIf you are a student a nd are interested in becoming more involved with the HI-ASM Student Chapte r\, please fill out this google form.\nIf you are interested in volunteeri ng with HI-ASM for the Spring Meeting\, please fill out this google form.\ nIf you are a Professor\, PI\, Researcher or professional in your field an d are interested in helping by being a judge at the Spring 2024 Meeting\, please fill out this google form.  CATEGORIES:Conference,Meeting LOCATION:JABSOM Medical Education Bldg.\, 651 Ilalo St.\, Honolulu\, HI\, 9 6813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educa tion Bldg.:geo:0,0 END:VEVENT BEGIN:VEVENT UID:426@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240424T120000 DTEND;TZID=Pacific/Honolulu:20240424T130000 DTSTAMP:20240424T013619Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarevalu ating-an-environmental-intervention-to-reduce-pulmonary-nontuberculous-myc obacteria-exposure-risk-in-hawaii-tiana-koch-ms-student SUMMARY:TRMD 690 Seminar:"Evaluating an Environmental Intervention to Reduc e Pulmonary Nontuberculous Mycobacteria Exposure Risk in Hawai’i"\, Tian a Koch\, MS Student DESCRIPTION:\nZoom Seminar\nContact jmeyer8@hawaii.edu for Zoom information .\n\nTiana Koch\nM.S. Student\nDepartment of Tropical Medicine\, Medical M icrobiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nHawai’i is a hot spot for nontuberculous mycobacterial (NTM) pulmonary disease (PD). Susceptibility to NTM infectio ns can be attributed to host risk factors such as smoking history\, existi ng bronchiectasis\, genetics\, ethnic background\, sex\, and age. Presumed infections are acquired through environmental exposures including inhalat ion of NTM-laden freshwater aerosols released from showerhead biofilms in a patient’s home environment. Using microbiological techniques\, we have previously recovered respiratory relevant (RR) NTM species including viab le isolates of Mycobacterium abscessus\, Mycobacterium chimaera\, Mycobact erium avium\, and Mycobacterium chelonae from homes of people with NTM PD in Hawai’i. Despite the ability of RR NTM to thrive in premise plumbing biofilms\, physical methods to reduce NTM exposure risk have not been adeq uately evaluated. In this pilot study\, we will investigate the efficacy o f a specific type of environmental intervention\, point of use (POU) filte r-containing\, handheld shower units\, as a method to reduce household NTM exposures for people in Hawai’i. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:425@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240424T100000 DTEND;TZID=Pacific/Honolulu:20240424T110000 DTSTAMP:20240415T213659Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-seminar-isabelle-eiserusing-and-optimizing-drosophila-s2-ex pression-systems-and-affinity-chromatography-for-recombinant-antigen-produ ction SUMMARY:Tropical Medicine MS Thesis Defense Seminar\, Isabelle Eiser:"Using And Optimizing Drosophila S2 Expression Systems and Affinity Chromatograp hy for Recombinant Antigen Production" DESCRIPTION:\nIn Person &\; By Zoom\nContact jmeyer8@hawaii.edu for Zoom information.\n\nIsabelle E. Yazel Eiser\nM.S. Candidate\nDepartment of Tr opical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Sch ool of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\nDevelopment of rec ombinant proteins that are key antigens of priority pathogens\, such as SA RS-CoV-2\, Nipah Virus (NiV)\, and Crimean-Congo Hemorrhagic Fever Virus ( CCHFV)\, are critical for public and global health research. Recombinant p roteins have numerous research and biopharmaceutical applications includin g the use in surveillance of potential outbreaks\, studying immunological responses to infection\, and the development of serological assays and vac cines. Biopharmaceutical use of recombinant proteins requires reproducible \, standardized\, and consistent protein production which can be achieved using the Drosophila S2 expression system and affinity purification method . Here we present a potential platform for the production of SARS-CoV-2 S pike (S) protein\, Nipah Virus (pre)fusion (pf/F)\, attachment (G)\, and n ucleocapsid (N) proteins as well as CCHFV receptor recognition glycoprotei n (Gc and Gn) and nucleocapsid (N) proteins using the Drosophila S2 expres sion platform. We demonstrate a universal\, tagless immunoaffinity purific ation method applicable to all SARS-CoV-2 variant Spike proteins by restor ing the CR3022-binding epitope in our engineered BA.1 and BA.5 spike varia nt constructs. NiV and CCHFV protein genes were purified using immobilized metal ion affinity chromatograph. This research allows for production of antigens for serological surveillance of disease\, monitoring of immunogen icity and efficacy of newly developed vaccines\, and recombinant subunit p rotein vaccine production to combat new and evolving viral diseases and co uld be used for the generation of other\, purpose-engineered vaccine antig ens. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:424@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240403T120000 DTEND;TZID=Pacific/Honolulu:20240403T130000 DTSTAMP:20240401T234524Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarpropo sed-baseline-study-on-the-seroprevalence-of-toxoplasma-gondii-and-associat ed-risk-factors-in-people-living-in-hawaii-jerrisa-ching-phd-student SUMMARY:TRMD 690 Seminar:"Proposed Baseline Study on the Seroprevalence of Toxoplasma gondii and Associated Risk Factors in People Living in Hawaii"\ , Jerrisa Ching\, PhD Student DESCRIPTION:\nIn Person and By Zoom\nContact jmeyer8@hawaii.edu for Zoom in formation.\n\nJerrisa Ching\, D.V.M.\, M.P.H.\nPh.D. Student\nDepartment o f Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nToxoplasmosi s is a global\, neglected tropical disease caused by the zoonotic protozoa n parasite\, Toxoplasma gondii\, which can be transmitted to humans by ing estion of contaminated raw meat\, food\, water\, and transplacental route. In Hawaii\, recent reports have shown that many animals are infected with T. gondii and have caused high morbidity and mortality in them. With many reports on toxoplasmosis in animals\, it is not well known how prevalent T. gondii is currently in human populations in Hawaii. The proposed baseli ne study will provide information on the seroprevalence of T. gondii IgG a ntibodies and associated risk factors of exposure in people. The findings will be relevant to implement disease surveillance and prevention programs to combat toxoplasmosis and safeguard the population health of Hawaii. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:423@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240327T120000 DTEND;TZID=Pacific/Honolulu:20240327T130000 DTSTAMP:20240325T222600Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarinves tigating-the-protective-role-of-the-vaccine-induced-humoral-immune-respons e-in-marburg-virus-and-sudan-virus-disease-troy-odo-ms-student SUMMARY:TRMD 690 Seminar:"Investigating the Protective Role of the Vaccine Induced Humoral Immune Response in Marburg Virus and Sudan Virus Disease"\ , Troy Odo\, MS Student DESCRIPTION:\nZoom Seminar\nContact jmeyer8@hawaii.edu for Zoom information \n\nTroy Odo\nPh.D. Student\nDepartment of Tropical Medicine\, Medical Mic robiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity o f Hawaiʻi at Mānoa\n\n\n\nFiloviruses cause severe disease in humans an d have led to several major outbreaks. Currently\, two vaccines have been approved to protect against Ebola virus (EBOV) infection\, but there are n o vaccines licensed to protect against any other filoviruses. The EBOV gly coprotein shares very limited homology with the Sudan virus (SUDV) and Mar burg virus (MARV) glycoproteins which eliminates the chance for cross-prot ection of EBOV specific vaccines. To address this problem\, our group deve loped adjuvanted recombinant glycoprotein subunit vaccines for EBOV\, MARV \, and SUDV. Monovalent SUDV and MARV vaccines as well as bivalent formula tions containing EBOV GP and either SUDV or MARV GP were tested for effica cy in cynomolgus macaques showing full protection against lethal doses of live MARV and SUDV. Our current work aims to further investigate the role of the humoral immune response in protection against these diseases which could help to direct future vaccine development efforts.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:421@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240313T120000 DTEND;TZID=Pacific/Honolulu:20240313T130000 DTSTAMP:20240307T003630Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-dis sertation-defensedissertation-defense-investigating-the-use-of-ultra-small -iron-oxide-nanoparticles-as-a-subunit-vaccine-delivery-platform-with-adju vant-like-properties-ane SUMMARY:Tropical Medicine Dissertation Defense:"Investigating the Use of Ul tra Small Iron Oxide Nanoparticles as a Subunit Vaccine Delivery Platform with Adjuvant-like Properties"\, Aneesa Golshan\, PhD Candidate DESCRIPTION:Zoom PhD Defense Seminar\nZoom Link: https://zoom.us/j/99966128 576?pwd=cXo3c3VKYkhPVytGemp4dTZmb2Fudz09\nMeeting ID: 999 6612 8576\nPassc ode: trmd690\n\nAneesa Golshan\nPh.D. Candidate\nDepartment of Tropical Me dicine\, Medical Microbiology and Pharmacology John A. Burns School of Med icine\, University of Hawaii at Manoa\n\n\n\nHighly engineered vaccines of ten display improved safety profiles in comparison to whole-cell vaccines\ , with reduced reactogenicity and safety profiles. However\, these platfor ms often result in lower immunogenicity and durability\, requiring additio nal immunological adjuvants to improve these qualities. Inorganic nanopart icles with built-in adjuvant properties as vaccine delivery may enhance im munogenicity without additional adjuvants. Our previous research indicates that functionalized iron-oxide nanoparticles (IO-NP) possess adjuvant-lik e properties and are internalized by bone marrow-derived dendritic cells. IO-NPs have shown to be safe in clinical applications\, and are inexpensiv e\, highly reproducible and can be lyophilized and multiplexed – qualiti es that are vital for vaccine development for global distribution. This pr oject further elucidates\, in vitro and in vivo\, the adjuvant-like activi ties of IO-NPs\, with a focus on dendritic cells at the innate-adaptive im mune interface\, and to correlate these activities with vaccine immunogeni city. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:420@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240306T120000 DTEND;TZID=Pacific/Honolulu:20240306T130000 DTSTAMP:20240305T235943Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarasses sing-the-impediments-associated-with-sars-cov-2-whole-genome-sequencing-re nn-silve-salomon-ms-student SUMMARY:TRMD 690 Seminar:"Assessing the Impediments Associated with SARS-Co V-2 Whole Genome Sequencing\," Renn Silve Salomon\, MS Student DESCRIPTION: \;\nIn Person &\; By Zoom\nContact corit@hawaii.edu for Zoom information\n\nRenn Silve Salomon\nM.S. Student\nDepartment of Tropi cal Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaiʻi at Mānoa\n\n\nAs of December 23\, 2023\, the State of Hawaii has submitted 33\,731 SARS-CoV-2 sequences to t he Global Initiative on Sharing all Influenza Data (GSAID) and GenBank dat abases\, which is 8% of all COVID-19 cases in Hawaii. The central objectiv e of this study is to develop protocols to enhance the submission of Hawai i SARS-CoV-2 sequences to public sequence repositories. The study aims are : 1) identify methodologies to increase submission of high-quality SARS-Co V-2 sequences\, and 2) validate the genome assembly strategy in predicting ambiguous bases identified in low coverage regions of the SARS-CoV-2 sequ ences. Development of new methodologies and efficient sequencing workflows will lead to the identification of novel variants that can aid in develop ment of updated vaccine formulations and expedited public health measures to combat the pandemic.\n\n\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:419@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240228T120000 DTEND;TZID=Pacific/Honolulu:20240228T130000 DTSTAMP:20240228T035129Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarvacci ne-advocacy-confidence-and-hesitancy-jack-crawford-sanofi-vaccines SUMMARY:TRMD 690 Seminar:"Vaccine Advocacy: Confidence and Hesitancy"\, Jac k Crawford\, Sanofi Vaccines DESCRIPTION:By Zoom\nContact corit@hawaii.edu for Zoom information\n\nJack Crawford\, PhD\nMedical Science Liaison\, Sanofi Vaccines\nSacramento\, CA \n\n\n\nJack is a Medical Science Liaison for the Sanofi Vaccines team. He covers Northern California\, Nevada\, and Arizona and is based in Sacrame nto\, California. He graduated from Indiana University – Bloomington wit h a Ph.D. in Virology where he studied the effects of RNA modifications on mosquito borne viruses. Jack has worked on various viruses over his nearl y decade long career at the lab bench\, including Chikungunya\, Zika\, Sin dbis\, Dengue\, West Nile\, Reovirus\, Rotavirus\, Bean Yellow Dwarf virus \, and Bean Dwarf Mosaic virus\, before joining the Sanofi Vaccines team i n 2023. He loves to travel with his fiancée and typically spends his week ends hiking and/or playing trivia and enjoying drinks at local craft brewe ries.\n\n"I’ll be going over a quick history of vaccine hesitancy\, what it is and why it’s important to be aware of\, some information to help combat some of the more prominent talking points of vaccine hesitancy\, an d finally\, the role HCPs play in advocating for vaccine uptake. Happy to stay on and answer questions about the talk or career related at the end a s well." CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:417@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240221T173000 DTEND;TZID=Pacific/Honolulu:20240221T183000 DTSTAMP:20240220T221047Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-social-determinants-of-health-across-empires-exploring-variatio ns-and-implications-in-historically-european-us-and-japanese-affiliated-re gions-of-the-pac SUMMARY:COBRE/Tropical Medicine Seminar: “Social Determinants of Health A cross Empires: Exploring Variations and Implications in Historically Europ ean-\, US-\, and Japanese-affiliated Regions of the Pacific and Caribbean Lessons from the Global COVID Study and the Diálogo Social Científico St udy“\, Timothy Dye\, University of Rochester School of Medicine & Dentis try DESCRIPTION: \;\nIn Person &\; By Zoom\nContact corit@hawaii.edu for Zoom information.\n\n\nTimothy Dye\, Ph.D.\nObstetrics and Gynecology\, P ediatrics\, Dentistry and Public Health\nUniversity of Rochester School of Medicine and Dentistry\n\nRochester\, New York\n\n\n\n\n\nDuring the impe rial era in the Pacific Islands and the Caribbean\, various European power s\, the United States\, and Japan extended their empires by establishing c olonies and exerting control over territories in these regions. The motiva tions for such expansion included economic prospects\, geopolitical locati on\, and other strategic and political considerations. The imperial era ha d profound effects on indigenous populations in the Pacific and Caribbean\ , leading to spread of disease\, rapid cultural change\, economic exploita tion\, and oppression. Some former colonies and territories gained indepen dence in the past century and some have not. The legacies of imperialism c ontinue to influence the social\, economic\, political\, and health landsc apes of these regions. This presentation will focus on emerging results fr om two recent studies\, one a global study of non-medical impacts of COVID and the other a study in Puerto Rico and among Puerto Ricans in the USA e xamining community attitudes toward science. We will examine -where possib le - results by the formerly colonized nations of the Pacific and Caribbea n\, and of the United States of America\, Western Europe\, and Japan. Such an analysis can help us assess if and how the imperial legacy of the late 19th to the early 20th century may continue to impact social determinants and health. The Rochester Global COVID Study was funded by the Richard W. and Mae Stone Goode Trust\, and Diálogo Social Científico was funded by the US National Institutes of Health’s Human Genome Institute\, Award # R21HG012136.\n\n\n\n\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:418@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240221T120000 DTEND;TZID=Pacific/Honolulu:20240221T130000 DTSTAMP:20240220T221736Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-immu nopathogenesis-of-hantavirus-infection-hemorrhagic-fever-with-renal-syndro me-and-hantavirus-cardiopulmonary-syndrome-rodson-zorilla-phd-student SUMMARY:TRMD 690 Seminar: "Immunopathogenesis of Hantavirus Infection: Hemo rrhagic Fever with Renal Syndrome and Hantavirus Cardiopulmonary Syndrome" \, Rodson Zorilla\, PhD Student DESCRIPTION:In Person &\; By Zoom\nFor Zoom information\, contact corit@ hawaii.edu\n\nRodson Zorilla\nPh.D. Student\n\nDepartment of Tropical Medi cine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medi cine\n\nUniversity of Hawaiʻi at Mānoa\n\n\n\nHantaviruses are a signif icant public health threat affecting 200\,000 people worldwide annually wi th a mortality rate of 35-40%. Distribution of rodent host species led to specific geographical pattern of the disease. Old World hantaviruses in As ia and Europe causes hemorrhagic fever with renal syndrome (HFRS) and New World Hantaviruses in the Americas causes hantavirus cardiopulmonary syndr ome (HCPS). It has been proposed that the interplay between viral effects and host immune response are contributory to the pathogenesis of hantaviru s infection. Impairment of endothelial barrier integrity and capillary lea kage is central to hantavirus syndromes\, but the mechanism on how the vir us causes pathology in the renal and cardiopulmonary systems remain unclea r. Performing pathogenesis study has been futile due to lack of experiment al disease models. This seminar will focus on the current understanding of hantavirus infection pathogenesis and current surrogate disease models us ed to study the pathogenesis of hantavirus infection.\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 303\, 651 Ilalo St.\, Honolulu\, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educa tion Bldg. Rm 303:geo:0,0 END:VEVENT BEGIN:VEVENT UID:416@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240214T120000 DTEND;TZID=Pacific/Honolulu:20240214T130000 DTSTAMP:20240214T073941Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarstudy -of-maturation-status-of-dengue-virus-and-dengvaxia-recipients-in-the-phil ippines-yu-ching-dai-phd-student SUMMARY:TRMD 690 Seminar:"Study of maturation status of dengue virus and De ngvaxia recipients in the Philippines"\, Yu-Ching Dai\, PhD Student DESCRIPTION:\nIn Person and By Zoom\nContact amyount@hawaii.edu for Zoom in formation\n\nYu-Ching Dai\nPh.D. Student\nDepartment of Tropical Medicine\ , Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\ nUniversity of Hawaiʻi at Mānoa\n\n\n\nDengue virus (DENV) is the leadi ng cause of mosquito-borne viral diseases afflicting humans in the tropics and subtropics. Dengvaxia\, a chimeric yellow fever tetravalent dengue va ccine\, is the first licensed dengue vaccine and is recommended by WHO for baseline DENV-immune individuals only\, due to higher risk of severe deng ue disease among DENV-naïve recipients. In 2016\, a Dengvaxia vaccination campaign was launched in the Philippines with >\;830\,000 children rece iving at least one dose without prior serostatus testing. Thousands of DEN V-naïve recipients are at high risk during future DENV infection. We prev iously developed a DENV1-4 nonstructural protein 1 (NS1) IgG ELISA with hi gh sensitivity/specificity and identified baseline DENV-naïve vaccinees f rom the participants of a fever surveillance program at the Research Insti tute for Tropical Medicine Philippines. We aimed to further characterize a ntibody responses among these recipients to improve our uderstanding of im mune responses induced by Dengvaxia and future vaccine development. We pre sent our preliminary results of our study\, which includes a larger sample size. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:415@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240207T120000 DTEND;TZID=Pacific/Honolulu:20240207T130000 DTSTAMP:20240206T235622Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-inge nuity-pathway-analysis-of-kawasaki-disease-genomic-datasets-tatiana-aguila r-ms-student SUMMARY:TRMD 690 SEMINAR: "Ingenuity Pathway Analysis of Kawasaki Disease G enomic Datasets"\, Tatiana Aguilar\, MS Student DESCRIPTION: \;\nIn Person &\; By Zoom\nContact amyount@hawaii.edu f or Zoom information.\n\nTatiana Aguilar\nM.S. Candidate\nDepartment of Tro pical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Scho ol of Medicine\nUniversity of Hawaiʻi at Mānoa\n \;\n\n\nIngenuity Pathway Analysis (IPA) software is an essential tool for visualizing canon ical pathways\, upstream and downstream regulators and signaling networks. IPA relies on its knowledgebase which utilizes over 100\,000 publications \, their associated data and analyses to develop disease based biological pathways. Several studies have published data using IPA to study gene expr ession in Kawasaki Disease (KD) patients. There are currently 13 data anal yses completed using 5 different gene expression datasets publicly availab le for reference within the IPA software. Nine of the analyses compare the sensitivity and resistance to intravenous immunoglobulin therapy and othe r potential therapeutic targets. Three analyses compare KD patients to hea lthy controls. The last analysis compares the acute and convalescent phase s of KD. While these studies provide insight into the effectiveness of the rapeutics\, the progression of KD from the acute to convalescent phase and formation of coronary artery lesions remains an enigma. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:437@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240205T120000 DTEND;TZID=Pacific/Honolulu:20240205T130000 DTSTAMP:20250131T222203Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=zoom-trmd-690-seminar translational-strategies-to-improve-oral-and-local-delivery-of-antiviral-d rugs SUMMARY:[Zoom] TRMD 690 Seminar:"Translational Strategies to Improve Oral a nd Local Delivery of Antiviral Drugs" DESCRIPTION:\nZoom\nZoom Link: https://us02web.zoom.us/j/81853192041?pwd=Dl S9NR8Q7JLSk7wgYACVanVFiTtcnz.1\nMeeting ID: 818 5319 2041\nPasscode: 56351 9\n\nAbhijit Date\, Ph.D.\nAssistant Professor of Pharmaceutical Sciences\ nDirector of Drug Preformulation\, Repurposing and Delivery\nDepartment of Pharmacology and Toxicology\nR. K. Coit College of Pharmacy\, University of Arizona\nThe suboptimal physicochemical characteristics such as high cr ystallinity\, and low and pH-dependent solubility\, and suboptimal biophar maceutical properties such as low permeability and bioavailability dramati cally impact the oral and/or local delivery of existing antiviral drugs as well as investigational antiviral candidates. Our research work amalgamat es nanotechnology with crystal engineering strategies such as hydrophobic salt synthesis and anticrystal engineering approaches such as ionic liquid synthesis to improve physicochemical and biopharmaceutical properties of “difficult-to-deliver” drugs. We are currently developing nano-scale i onic liquids (NAILs) to enhance the oral bioavailability and tissue penetr ation of antiretroviral drugs such as rilpivirine and dolutegravir and inv estigational anti-herpetic drugs such as BX795. Additionally\, we are acti vely pursuing the development of once-daily topical eyedrops for the impro ved treatment of ocular herpes simplex virus infections. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:414@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240131T120000 DTEND;TZID=Pacific/Honolulu:20240131T130000 DTSTAMP:20240129T210939Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarexami ning-the-health-concerns-of-environmental-contamination-through-the-lens-o f-food-security-catherine-pirkle-phd SUMMARY:TRMD 690 Seminar:"Examining the Health Concerns of Environmental Co ntamination Through the Lens of Food Security"\, Catherine Pirkle\, PhD DESCRIPTION:\nIn Person and By Zoom\nContact amyount@hawaii.edu for passcod e.\n\nCatherine Pirkle\, PhD\nAssociate Professor\nOffice of Public Health Studies\nThompson School of Social Work and Public Health\n\n\n\nAbstract :\nThis presentation will apply the Committee on World Food Security Frame work to comprehensively examine health concerns associated with exposure t o environmental contaminants\, such as mercury\, lead\, and polychlorinate d bi-phenyls. It will focus on marine contaminants and fish consumption\, but will also address emerging concerns from recent per- and poly-fluoroal kyl substances detection on Oʻahu and environmental exposures from the Ma ui Wildfires. Research presented during this session will cover multiple g eographical contexts and highlight health concerns of particular relevance to Indigenous Peoples and Islanders.\nBiography:\nCatherine Pirkle is an Associate Professor of Public Health at the University of Hawaiʻi at Mān oa. Trained in both life-course and environmental epidemiology\, she has w orked for two decades in the field of women’s health. Her research has b rought her to West Africa\, where she completed several projects evaluatin g interventions to reduce maternal and perinatal mortality. She has also s pent over a decade examining pivotal reproductive health milestones across the life-course—age at first birth\, lifetime childbirths\, age and typ e of menopause—and their associations with chronic disease\, frailty\, a nd mobility disability. Her training in environmental epidemiology has bro ught her to the Canadian Arctic\, Bermuda and Colombia where she conducted research and provided technical assistance to better document and underst and the impacts of environmental contamination on food security and ultima tely\, the health of pregnant women and their children. She has extended t his research to the Pacific region and has current projects in Hawaiʻi on marine pollution\, food security\, and disasters. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:413@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240124T120000 DTEND;TZID=Pacific/Honolulu:20240124T130000 DTSTAMP:20240124T021302Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-my-r esearch-and-academic-journey-through-the-covid-19-pandemic-at-the-departme nt-of-tropical-medicine-multiplex-microsphere-immunoassay-for-testing-sars -cov-2-igg-levels-in SUMMARY:TRMD 690 Seminar:” My Research and Academic Journey Through The C OVID-19 Pandemic at The Department of Tropical Medicine: Multiplex Microsp here Immunoassay For Testing SARS-CoV-2 IgG Levels In Infected and/or Vacc inated Individuals”\, Maansi Murty\, MS Student DESCRIPTION: \;\nIn Person &\; By Zoom\nZoom ID:  999 6612 8576\nCo ntact amyount@hawaii.edu for passcode.\n\nMaansi Murty\n\nM.S. Candidate\n Department of Tropical Medicine\, Medical Microbiology and Pharmacology\nJ ohn A. Burns School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\n For the past 4 years\, COVID-19 has played a pivotal role in how we have s haped our society and daily lives. As the COVID-19 pandemic continues to b e a daily presence\, it is imperative that we take a retrospective look at the developments we have made thus far. In today’s seminar\, I will rev iew my academic and research contributions during the pandemic in Hawai’ i until now\, and highlight some key projects involved in studying this di sease. From the establishment of the Palolo Valley Homes COVID-19 clinic i n 2020\, to the development of low-cost\, accessible screening technology for SARS-CoV-2 IgG antibodies\, to finally comparing a laboratory-develope d microsphere assay to a commercial kit for quantitation of SARS-CoV-2 ant ibodies\, we have made great strides in understanding a new pathogen. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:411@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240116T100000 DTEND;TZID=Pacific/Honolulu:20240116T110000 DTSTAMP:20240201T211314Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=one-health-month-semi narclimate-change-its-about-health-elizabeth-keifer-jabsom SUMMARY:One Health Month Seminar:"Climate Change: It's About Health"\, Eliz abeth Keifer\, JABSOM DESCRIPTION:\nZoom Webinar\n\n\n\nZoom Meeting ID: 917 8333 1725 Passcode: 366935 Link: https://zoom.us/j/91783331725?pwd=QUVNMUJxSnpLc1gvMnlmYjdPOFZ rUT09\n\n\n\nElizabeth Kiefer\, MD Assistant Clinical Professor John A. Bu rns School of Medicine University of Hawaii at Manoa\n\n\n\nDr. Elizabeth Kiefer completed a residency in Internal Medicine at The Mount Sinai Hospi tal in New York City\, followed by a fellowship in Epidemiology at Columbi a University. She is an Assistant Clinical Professor at JABSOM and has wor ked in Primary Care and HIV/AIDS care. Dr. Kiefer recently completed a cer tificate program on climate and health for health care professionals at Ya le University. She will discuss an overview of climate change and its diff erent health impacts in Hawaii using a CDC climate and health wheel resour ce. For more information\, check out the UH One Health website at https:// manoa.hawaii.edu/onehealth/ or contact Jerrisa Ching (email: jching21@hawa ii.edu).\nRecording of Dr. Keifer's Seminar\n\n\n\nSponsored by the UH Man oa One Health Workgroup\, John A. Burns School of Medicine\, and the Depar tment of Tropical Medicine\, Medical Microbiology\, and Pharmacology.\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:412@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240110T120000 DTEND;TZID=Pacific/Honolulu:20240110T130000 DTSTAMP:20240110T190534Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarchara cterizing-the-longitudinal-kinetics-of-sars-cov-2-post-symptom-onset-nicol as-miwa-trmd-ms-student SUMMARY:TRMD 690 Seminar:"Characterizing the Longitudinal Kinetics of SARS- CoV-2 Post-Symptom Onset"\, Nicolas Miwa\, TRMD MS Student DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link:  https://zoom.us/j/9996 6128576?pwd=cXo3c3VKYkhPVytGemp4dTZmb2Fudz09\nCall in: (669) 900-6833\nZoo m ID:  999 6612 8576\nPasscode: trmd690\n\nNicholas Miwa\nM.S. Student\nD epartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJo hn A. Burns School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nT he ongoing global COVID-19 pandemic has fundamentally changed the landscap e of public health\, necessitating sustained research efforts to understan d\, mitigate\, and manage its multifaceted impact. Despite the short timef rame\, numerous scientific advancements have been made in rapid diagnostic testing\, vaccine development\, and surveillance on a global scale. Howev er\, routine SARS-CoV-2 molecular assays used for diagnostic testing are u nable to distinguish between actively replicating RNA and noninfectious RN A during an acute infection\, and the duration of infectiousness after sym ptom onset is still not yet clearly defined. In today’s seminar\, I will be introducing our longitudinal SARS-CoV-2 cohort and how we will be util izing multiple diagnostic testing methods to potentially determine the win dow of infectiousness in symptomatic SARS-CoV-2-positive individuals.\nSem inar Schedule: https://docs.google.com/document/d/1u6cTLDbI2EjVhVP5Xk5KgG1 pUxaDj3do/edit?usp=sharing&\;ouid=106174576499958424248&\;rtpof=true &\;sd=true CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:410@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20240109T160000 DTEND;TZID=Pacific/Honolulu:20240109T170000 DTSTAMP:20240109T191854Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=one-health-month-semi nar2023-maui-wildfires-one-health-dimensions-and-response SUMMARY:One Health Month Seminar:"2023 Maui Wildfires: One Health Dimension s and Response"\, Neil Vezeau DESCRIPTION:Zoom Webinar\nZoom Meeting ID: 948 7897 3057\nPasscode: 735346\ nLink: https://zoom.us/j/94878973057?pwd=Qno2RkRKNFUrVVFLd080VWpqTWVFQT09\ nNeil Vezeau\, DVM\, MPH\nFounder\, International Student One Health Assoc iation\nThe 2023 Maui wildfires were devastating for the people\, animals\ , and environment of the Valley Isle. Meeting the destruction across these domains\, many local\, national\, and international efforts from a divers ity of actors in a One Health fashion. This talk will focus on the burn pa tients in a shelter medicine context\, effected large animal operations\, ecological effects downstream from the fires\, and the coordination of res ponse efforts from state\, federal\, private\, and non-governmental organi zation actors.\nFor more information\, check out the UH One Health website at https://manoa.hawaii.edu/onehealth/ or contact Jerrisa Ching (email: j ching21@hawaii.edu).\n\nSponsored by the UH Manoa One Health Workgroup\, J ohn A. Burns School of Medicine\, and the Department of Tropical Medicine\ , Medical Microbiology\, and Pharmacology. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:409@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231206T120000 DTEND;TZID=Pacific/Honolulu:20231206T130000 DTSTAMP:20231205T193249Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminaradvan cing-filovirus-vaccine-development-developing-high-yield-platforms-to-expr ess-and-purify-marburg-virus-glycoprotein-and-other-vaccine-targets-ludwig -mayerlen-phd-student SUMMARY:TRMD 690 Seminar:"Advancing Filovirus Vaccine Development: Developi ng high-yield platforms to express and purify Marburg virus glycoprotein a nd other vaccine targets"\, Ludwig Mayerlen\, PhD Student DESCRIPTION: \;\nIn Person &\; By Zoom\nContact amyount@hawaii.edu f or Zoom information.\n\nLudwig Mayerlen\nPh.D. Student\nDepartment of Trop ical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Schoo l of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nEffective recombin ant protein expression is important in vaccine development and monoclonal antibody production. We are currently in late-stage preclinical developmen t of a trivalent filovirus vaccine candidate against the three most pathog enic filoviruses\, namely Zaire ebolavirus\, Sudan ebolavirus\, and Marbur g marburgvirus. We need to optimize our current production process to crea te pilot-scale quantities of Marburg virus glycoprotein (MARV GP). To real ize our objective\, we have engineered a novel and proprietary system that consists of a new expression vector and a genetically modified S2 insect cell line. The design of this system is tailored to enhance the production of high-quality antigens with yields exceeding those previously attained. To obtain pure vaccine antigens in native-like conformations\, we utilize immunoaffinity chromatography (IAC). The second part of my talk will focu s on the in-house production of antibodies for IAC. In the third part\, I will introduce a platform for the discovery of nanobodies that could impro ve our current IAC process and potentially help us respond more rapidly to emerging infectious diseases. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:407@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231201T123000 DTEND;TZID=Pacific/Honolulu:20231201T133000 DTSTAMP:20231122T015413Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=dissertation-defense- seminarin-vivo-and-in-vitro-investigation-of-sars-cov-2-associated-injury- and-functional-impairments-in-the-testis-stefanos-giannakopoulos-phd-candi date SUMMARY:Dissertation Defense Seminar:"In-vivo and in-vitro investigation of SARS-CoV-2 associated injury and functional impairments in the testis"\, Stefanos Giannakopoulos\, PhD Candidate DESCRIPTION:\nIn Person &\; By Zoom\nZoom Link: https://hawaii.zoom.us/j /98685877294\nCall in: (669) 900-6833\nZoom ID: 986 8587 7294\nPasscode: 5 36167\n\nStefanos Giannakopoulos\nPh.D. Candidate\nDepartment of Cell and Molecular Biology\nJohn A. Burns School of Medicine\nUniversity of Hawaiʻ i at Mānoa\n\n\n\nTraditionally associated with shortness of breath and lung injury\, the 2019 severe-acute respiratory syndrome coronavirus 2 pan demic presented several other alarming features in COVID-19 patients\, inc luding cytokine storm and injury of other organs such as the kidney and te stis. Infected males also experienced symptoms such as orchitis\, erectile dysfunction\, reduced testosterone levels\, and low sperm count. These te sticular symptoms are accompanied by leukocyte infiltration\, sloughing of the seminiferous tubules\, and germ cell death. Cohorts of studies from C OVID-19 moderate\, severe\, and critical patients have revealed additional hormone alterations as well as functional damages to function of the male reproductive tract. These include decreased semen volume\, lower sperm co unt\, decreased testosterone\, follicular stimulating hormone\, and lutein izing hormone. While most of these parameters recover rapidly upon recover y from the disease\, long-term follow up of recovered patients suffering f rom long-COVID revealed lower testosterone levels and reduced sperm parame ters up to 12 months after disease onset. Therefore\, it is still unclear what the mechanism of testicular injury is and what are the specific immun e mechanisms responsible for contributing to SARS-CoV-2 testicular short-t erm and long-term pathogenesis. We here demonstrate that human testis cann ot support productive SARS-CoV-2 infection. This suggests that the mechani sm of testicular injury observed in COVID-19 patients is a bystander effec t of infection. We utilized different 2D and 3D testicular models\, optimi zed in our lab\, to characterize the effect of the SARS-CoV-2 infection-de rived inflammatory mediators and antigens\, on the testicular cells. We al so use K18-hACE2 mice to characterize various aspects of testicular pathog enesis associated with SARS-CoV-2 in vivo. These include histopathology st udies during the acute stage and short-term after recovery and the correla tion between systemic cytokine storm and different markers of testicular i njury and function. Lastly\, we used high throughput RNA-seq approach to i dentify the molecular signatures associated with SARS-CoV-2 infection in t he K18-hACE2 mouse testis. The outcome of this study provides significant mechanistic insights into the testicular injury and effects during the acu te and recovery stage of SARS-CoV-2 on testicular function. It also addres ses fundamental gaps in our understanding of how this virus affects male r eproductive health. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:408@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231129T120000 DTEND;TZID=Pacific/Honolulu:20231129T130000 DTSTAMP:20231128T015259Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarusing -and-optimizing-drosophila-s2-expression-systems-and-affinity-chromatograp hy-for-recombinant-protein-production-isabelle-eiser-ms-student SUMMARY:TRMD 690 Seminar:"Using And Optimizing Drosophila S2 Expression Sys tems and Affinity Chromatography for Recombinant Protein Production"\, Isa belle Eiser\, MS Student DESCRIPTION: \;\nIn Person &\; By Zoom\nContact amyount@hawaii.edu f or Zoom information.\n\nIsabelle E. Yazel Eiser\nM.S. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burn s School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\nRecombinant p roteins have been used in research and medical applications for decades wi th some notable uses including the Hepatitis B\, Herpes Zoster\, and COVID -19 vaccines. Medicinal use of these proteins requires reproducible\, stan dardized\, and consistent protein production which can be achieved through cell-based expression systems and affinity chromatography. We are investi gating the production of recombinant subunit proteins for SARS-CoV-2\, Nip ah Virus\, and Crimean-Congo Hemorrhagic Fever Virus using Drosophila S2 c ell lines and purification using affinity and tag-less immunoaffinity meth ods. This research allows for production of antigens for serological surve illance of multiple diseases\, monitoring of immunogenicity and efficacy o f newly developed vaccines\, and recombinant subunit protein vaccine produ ction to combat new and evolving viral diseases and could be used for the generation of other\, purpose-engineered vaccine antigens.\n \; CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:406@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231122T120000 DTEND;TZID=Pacific/Honolulu:20231122T130000 DTSTAMP:20231122T014426Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarscree ning-of-hawaiian-marine-extracts-for-antiviral-activity-against-sars-cov-2 -jonathan-fierro-phd-student SUMMARY:TRMD 690 Seminar:"Screening of Hawaiian Marine Extracts for Antivir al Activity Against SARS-CoV-2"\, Jonathan Fierro\, PhD Student DESCRIPTION:\nIn Person &\; By Zoom\nContact amyount@hawaii.edu for Zoom connection information.\n\nJonatan Fierro\nPh.D. Student\nDepartment of T ropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Sc hool of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nVaccination aga inst COVID-19 has been successful in controlling transmission of the virus and reducing disease severity. However\, it is observed that a myriad of symptoms including brain fog and respiratory complications linger for week s\, months\, or even years after the initial diagnosis. Currently there is only one FDA approved antiviral drug for the treatment of COVID-19\, ther efore\, the identification of new compounds that can effectively reduce vi rus replication and associated inflammation is urgently needed. This colla borative study uses a Natural Product Library (NPL) composed of more than 1000 Hawaiian marine extracts (ME) developed by the Hawai’i Pacific Univ ersity research team to screen for anti-SARS-CoV-2 compounds. We have scre ened ~500 marine extracts from different sources and have identified poten tial hits with >\;90% inhibitory capacity against SARS-CoV-2 in an in vi tro model. Further\, priority active extracts have been fractionated by LC -Mass spectroscopy and we have identified the fraction with most antiviral activity. Ongoing studies are focused on further characterizing the activ e compounds in these marine extracts. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:405@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231115T120000 DTEND;TZID=Pacific/Honolulu:20231115T130000 DTSTAMP:20231113T230424Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-the- public-health-significance-and-possible-methods-for-controlling-plasmodium -knowlesi-mallory-wilson-ms-student SUMMARY:TRMD 690 Seminar: "The Public Health Significance and Possible Meth ods for Controlling Plasmodium Knowlesi"\, Mallory Wilson\, MS Student DESCRIPTION: \;\nZoom Seminar Only\nContact amyount@hawaii.edu for Zoom link.\n\nMallory Wilson\, MPHTM\nM.S. Student\nDepartment of Tropical Med icine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Med icine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nOver the past few decades\ , major strides have been made in the way of malaria elimination in the hu man population. With these achievements\, the discussion of further preven tion programs have been brought to the table along with the goal\, put for th by the World Health Organization\, to eliminate malaria in 30 countries by 2030. This ambitious goal has shed light on the numerous barriers that stand in the way of malarious areas achieving their elimination status. S ince the turn of the millennium\, a zoonotic Plasmodium species known as P lasmodium knowlesi\, which is normally found in simian hosts\, has become more prevalent in humans across SouthEast Asia\, namely Malaysia. With thi s\, various studies have highlighted the issue of P. knowlesi cases remain ing underreported due to their incorrect microscopic detection and identif ication. This rise in zoonotic malaria cases sheds light on a new era of m alaria control\, diagnosis\, treatment and prevention. Many countries\, in cluding Malaysia\, were successful in many of their recent malaria control programs\, but have been unable to be declared “Malaria Free” due to the new attention put upon P. knowlesi. This presentation will detail the current status of P. Knowlesi and the possible protocols that should be ad opted for its control. Suggestions for navigating ongoing malaria eliminat ion while simultaneously controlling simian malaria will be detailed. END:VEVENT BEGIN:VEVENT UID:404@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231108T120000 DTEND;TZID=Pacific/Honolulu:20231108T130000 DTSTAMP:20231107T021149Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarpoten tial-antiviral-drugs-for-the-treatment-of-flavivirus-infections-jaymie-bil og-mina-ms-student SUMMARY:TRMD 690 Seminar:"Potential Antiviral Drugs for the Treatment of Fl avivirus Infections"\, Jaymie Bilog-Mina\, MS Student DESCRIPTION:\nIn Person &\; By Zoom\nContact amyount@hawaii.edu for Zoom connection information.\n\nJaymie Bilog-Mina\nM.S. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nMosquito-born e flaviviruses\, such as Dengue (DENV) and West Nile (WNV)\, have a global distribution and affect thousands of people annually. Indigenous Pacific People (IPP) in Hawaii are at significant risk of poverty-linked infectiou s diseases caused by mosquito-borne viruses due to their higher rates of c hronic diseases like diabetes. Although specific antiviral treatment optio ns for these viruses are currently unavailable\, drug repurposing screenin g of FDA-approved drugs offers a cost- effective and quick solution that c an be rapidly advanced to clinical trials. The flavivirus NS3 protein play s a critical role in virus replication within the rough endoplasmic reticu lum (RER). Identifying potential inhibitors through screening 24 FDA-appro ved compounds that may disrupt the NS3/NS4B binding will eventually lead t o virus propagation inhibition. Thus\, this study proposes to investigate the potential of FDA-approved drugs to inhibit NS3/NS4B binding and preven t flavivirus multiplication in Pacific Islanders at higher risk of infecti on\, contributing to the development of an effective antiviral therapy aga inst flavivirus infections. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:403@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231104T100000 DTEND;TZID=Pacific/Honolulu:20231104T140000 DTSTAMP:20231026T231557Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-american-socie ty-for-microbiology-hi-asm-fall-meeting SUMMARY:Hawai‘i American Society for Microbiology (HI-ASM) Fall Meeting DESCRIPTION:\nKeynote Speaker\n \;\nDr. Brian T. Murphy\, PhD\nASM Dist inguished Lecturer\nProfessor Pharmaceutical Sciences\nUniversity of Illin ois at Chicago\n \;\nTitle: Discovery of new antibiotic demethoxytetro nasin using novel solid support assay (DAPA)\nFor meeting agenda\, go to: https://www.hi-asm.org/2023fallmeeting CATEGORIES:Meeting LOCATION:Ala Moana Hotel\, Hibiscus Rm. II\, 2nd Floor\, 410 Atkinson Drive \, Honolulu\, HI\, 96814\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=410 Atkinson Drive\, Honolu lu\, HI\, 96814\, United States;X-APPLE-RADIUS=100;X-TITLE=Ala Moana Hotel \, Hibiscus Rm. II\, 2nd Floor:geo:0,0 END:VEVENT BEGIN:VEVENT UID:402@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231103T120000 DTEND;TZID=Pacific/Honolulu:20231103T130000 DTSTAMP:20231026T215441Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hi-asm-student-focuse d-seminar-what-are-my-career-options-and-how-do-i-get-there-dr-brian-murph y SUMMARY:HI-ASM Student Focused Seminar: "What are my career options and how do I get there?"\, Dr. Brian Murphy DESCRIPTION:\nDr. Brian T Murphy\, PhD\nASM Distinguished Lecturer\nProfess or\, Pharmaceutical Sciences\nUniversity of Illinois at Chicago\n\n\n\n\n\ nTitle: What are my career options and how do I get there?  Demystifying the path toward academia\, industry\, and alternative careers in science.\ n\n\n\nDr. Murphy has served as a panelist for career development on sever al occasions.  The presentation will describe aspects of a professorship that are often not communicated to trainees interested in academia.\n\nReg ister online at www.HI-ASM.org by 10/30/2023. CATEGORIES:Seminar LOCATION:Kapiolani Community College\, Ohia #118\, 4303 Diamond Head Rd\, H onolulu\, HI\, 96816\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=4303 Diamond Head Rd\, Hono lulu\, HI\, 96816\, United States;X-APPLE-RADIUS=100;X-TITLE=Kapiolani Com munity College\, Ohia #118:geo:0,0 END:VEVENT BEGIN:VEVENT UID:400@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231103T100000 DTEND;TZID=Pacific/Honolulu:20231103T110000 DTSTAMP:20231019T011110Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=one-health-day-semina rone-health-approaches-to-zoonotic-disease-prevention-preparedness-respons e-kevin-j-olival-phd-ecohealth-alliance SUMMARY:One Health Day Seminar:"One Health Approaches to Zoonotic Disease P revention\, Preparedness & Response\," Kevin J. Olival\, PhD\, EcoHealth A lliance DESCRIPTION:\nZoom Seminar\nZoom Meeting ID: 913 4624 2709\nPasscode: 19163 6\n\nSpeaker\nKevin J. Olival\, PhD\nVice President for Research\nEcoHealt h Alliance\n \;\nAbstract\nZoonotic diseases\, or those that jump betw een animal species and humans\, make up the majority of novel infectious d iseases and are primarily driven to emerge due to anthropogenic factors in cluding land-use change\, climate change\, development\, and agricultural expansion. However\, the specific mechanisms that influence disease transm ission\, prevalence\, and cross-species disease “spillover” are still not elucidated for most diseases and most ecosystems. Our current lack of understanding of these processes impedes our ability to develop and implem ent mitigation measures. Integrated ‘One Health’ research and policy a pproaches\, at the nexus of ecology\, biodiversity science\, infectious di sease dynamics\, human and veterinary research\, and socio-economics are n eeded given the complexities and global impact of emerging infectious dise ases (EIDs). For example\, new policy approaches that holistically conside r risk factors\, ecosystem services\, economics\, and health\, i.e.\, emer ging infectious disease risk assessments\, should be incorporated into lan d-use decision making. In this talk I will give an overview of my research and other initiatives at EcoHealth Alliance designed to strengthen emergi ng disease prevention at the landscape-animal-human interface where they a re needed most – particularly in lower-middle income countries in “EID hotspot” regions of the world. This will include: examples of how multi -sector disease surveillance and training can improve preparedness for EID s\; how simple diagnostic tools (e.g.\, conserved virus-family PCRs) can l ead to early detection and response of novel virus threats\; how spatial a nd ecological models allow us to better target zoonotic disease surveillan ce to the species\, locations and interfaces where they will be most cost- effective\; and\, lastly\, five policy recommendations for strengthening O ne Health systems for zoonoses prevention.\nFor more information\, contact Sandra P. Chang (email: sandrac@hawaii.edu\; phone: 808-692-1607)\nSponso red by the UH Manoa One Health Workgroup: John A. Burns School of Medicine \, College of Tropical Agriculture and Human Resources\, School of Ocean a nd Earth Science and Technology\, and Thompson School of Social Work and P ublic Health. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:401@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231101T120000 DTEND;TZID=Pacific/Honolulu:20231101T130000 DTSTAMP:20231019T012554Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=phd-dissertation-defe nse-for-olivia-a-smith-mphassessing-vaccine-efficacy-and-seroprevalence-us ing-multiplex-immunoassays-development-validation-and-applications-in-dive rse-populations SUMMARY:PhD Dissertation Defense for Olivia A. Smith:"Assessing Vaccine Eff icacy and Seroprevalence Using Multiplex Immunoassays: Development\, Valid ation\, and Applications in Diverse Populations" DESCRIPTION:\nIn Person &\; By Zoom\nContact corit@hawaii.edu for Zoom i nformation.\n\nOlivia A. Smith\, MPH\nPh.D. Candidate\nDepartment of Tropi cal Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\nPublic health policies rely on scientific discoveries\, particularly results from reliable tools identifying pathogen exposure and vaccine effectiveness. Multiplex immuno assays (MIAs) efficiently identify humoral immune markers of vaccine effic acy and previous viral exposure. As versatile seroepidemiological instrume nts\, MIAs offer insights into geographical indicators of past outbreaks\, allowing for the detection of immunological signatures of different vacci nes in diverse populations\, including those with altered metabolic condit ions. If assay reproducibility is assured\, these tools can be widely used to prevent epidemic-causing diseases\, including those caused by coronavi ruses and filoviruses. The successful production and purification of SARS- CoV-2 recombinant protein subunits\, expressed from Drosophila S2 cell lin es\, provide subsequent investigations with highly pure proteins for detec tion assays\, including MIAs. Standardized protocols for SARS-CoV-2 vaccin e response analyses were formulated by optimizing the MIA and using purifi ed protein. Recognizing the need for accessible validation protocols\, we have formulated and assessed the analytical parameters for the MIA. With q uantitatively validated assays\, seroprevalence and vaccine efficacy asses sments are reliable and reproducible in various settings\, increasing acce ssibility to validated outcomes. We analyzed vaccine efficacy in the conte xt of altered metabolic states through the optimized and validated MIA. Ou r findings reveal diminished immune responses in diabetic and obese mice c ompared to their healthy counterparts. Post-vaccination with adjuvanted su bunit or mRNA lipid nanoparticle (LNP) vaccines\, both humoral and cell-me diated immune responses were significantly reduced in diabetic and obese m ice. These results suggest that the observed impairment in humoral and cel l-mediated responses within altered metabolic states may be linked to chro nic inflammation associated with obesity and suboptimal glycemic control i n diabetes. Collectively\, these studies provide insights into the optimiz ation of tools for detecting immune responses through the production of SA RS-CoV-2 subunit panels\, emphasize the importance of assay validation for robust quantitative assessments of analytical parameters\, and highlight the challenges associated with vaccine efficacy in the context of altered metabolic states.\nFor further information\, contact Dr. Vivek R. Nerurkar - Tel. 808-692-1668\; email: nerurkar@hawaii.edu CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:397@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231030T140000 DTEND;TZID=Pacific/Honolulu:20231030T153000 DTSTAMP:20230927T212345Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-car eer-development-workshop SUMMARY:Tropical Medicine Career Development Workshop DESCRIPTION:\nIn Person &\; By Zoom\nUniversity of Hawaii\nJABSOM\, Kaka ako Campus\nMedical Education Building Auditorium\, Room 315\nZoom Link: h ttps://zoom.us/j/97543460620?pwd=K2t1TUE0MGxidXFOVkpTcnJyNHpCZz09\nCall in : (669) 900-6833\nZoom ID: 975 4346 0620\nPasscode: 276071\n\nGain insight s and practical strategies for success in job interviews and negotiations from a career expert and a Tropical Medicine graduate\n\n\n\nJob Search Ti ps &\; Strategies\nThomas Tsutsumoto\, MA\nCareer Counselor\nManoa Care er Center\nHonolulu\, Hawaii\n\n\n\n\nPractical Advice from a Young Scient ist (and JABSOM Tropical Medicine Graduate)\nBoonyanudh Jiyarom\, MS\nSeni or Research Associate\nTornado Bio\, South\nSan Francisco\, California CATEGORIES:Workshop LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:399@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231018T120000 DTEND;TZID=Pacific/Honolulu:20231018T130000 DTSTAMP:20231017T192240Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarbroad -acting-therapeutics-for-envenomation-using-candidate-inhibitors-of-conser ved-venom-toxins-raechel-kadler SUMMARY:TRMD 690 Seminar"Broad Acting Therapeutics for Envenomation using C andidate Inhibitors of Conserved Venom Toxins"\, Raechel Kadler DESCRIPTION:\nBy Zoom Only\nContact corit@hawaii.edu for Zoom connection in formation\n\nRaechel Kadler\nPh.D. Student\nDepartment of Tropical Medicin e\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicin e\nUniversity of Hawaiʻi at Mānoa\n\n\n\nAnnually\, there are millions of snake-\, spider-\, scorpion-\, hymenopteran- and jellyfish-\nenvenomati ons that result in both death and injury. The availability of healthcare a nd of useful therapeutics\, such as antivenoms\, represent critical challe nges to optimal outcomes and survival. Available antivenoms are expensive\ , require cold-chain storage\, and have a limited shelf life. Morbidity ca n result in life-long care requirements and the associated costs. Importan tly\, most of these incidents occur in remote environments where it is dif ficult to identify the culpable animal as well as obtain therapeutics in a timely manner. While venom composition\, a complex mixture of proteins\, enzymes\, lipids and small molecules\, varies across species\, there are e ssential components that have been conserved across evolution. These compo nents\, while necessary for prey capture and digestion\, result in common pathophysiology in the victim. These include tissue necrosis\, coagulopath ies\, porin-based sequelae such as pulseless electrical activity and acute cardiopulmonary collapse. Inhibitors of these venom components represent strong candidates for therapeutics. Specifically\, we will assess the effi cacy of inhibitors to lipase\, metalloproteinase and pore-forming enzyme a ctivity in both snake and cubozoan venoms. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:398@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20231011T120000 DTEND;TZID=Pacific/Honolulu:20231011T130000 DTSTAMP:20231010T011222Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarprofi ling-b-cell-immune-responses-to-vaccination-jourdan-mcmillan-phd SUMMARY:TRMD 690 Seminar:"Profiling B Cell Immune Responses to Vaccination" \, Jourdan McMillan\, PhD DESCRIPTION:\nIn Person &\; By Zoom\nContact corit@hawaii.edu for Zoom c onnection information\n\nJourdan McMillan\, Ph.D.\nInstructor\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burn s School of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nAntibody le vels and memory B cells are common measures of vaccine immunogenicity. Whi le they are useful for understanding ongoing and memory responses\, B cell s at all stages of development can potentially respond to vaccines and the ir components. Our lab has demonstrated that PRR ligands\, currently being investigated as vaccine adjuvants\, can drive the maturation of immature\ , transitional B cells\, however\, their effects on other B cell populatio ns is not completely understood. Understanding how vaccines and their comp onents affect various B cell populations will add to the big picture of va ccine immunogenicity. Additionally\, ethnic differences in response to vac cination has been noted. This seminar will summarize ongoing research eval uating the impact of immunogenic vaccine components on various B cell popu lations and ethnic differences in B cell responses to COVID-19 vaccination in Filipinos and non-Filipinos residing in Hawaiʻi. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:396@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230927T120000 DTEND;TZID=Pacific/Honolulu:20230927T130000 DTSTAMP:20230926T024138Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-deve lopment-and-evaluation-of-recombinant-proteins-for-the-serosurvey-of-lassa -fever-virus-and-other-emerging-and-re-emerging-viruses-in-humans-and-anim als-varney SUMMARY:TRMD 690 Seminar:” Development and Evaluation of Recombinant Prot eins for The Serosurvey of Lassa Fever Virus and Other Emerging and Re-eme rging Viruses in Humans and Animals”\, Varney Kamara\, PhD Student DESCRIPTION:By Zoom only\nContact corit@hawaii.edu for Zoom information\n&n bsp\;\nVarney Menipakeh Kamara\nPh.D. Student\nDepartment of Tropical Medi cine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medi cine\nUniversity of Hawaiʻi at Mānoa\n\n\n\nDeveloping sensitive and sp ecific methods for conducting serosurvey for Lassa fever virus (LASV) and other emerging and re-emerging viruses in Liberia is critical for preventi ng and controlling zoonotic diseases. Using a multiplex bead-based assay\, the recombinant viral antigens\, including LASV glycoprotein (GP) and nuc leoprotein (NP)\, Ebola\, Sudan and Marburg viruses GP\, chikungunya virus (CHIKV) envelope-2\, and SARS-CoV-2 spike and NP\, were used to assess th e seroprevalence potential of 200 field collected serum samples from human s\, dogs and rodents. Our multiplex bead-based immunoassay showed the reac tivity of human and animal IgG to the different recombinant viral antigens .  Spearman’s correlation of positive sample median fluorescence intens ity showed a high correlation between antigens of the same pathogen and cr oss-reactivity with antigens of different viruses from the same viral fami ly. In humans\, we observed high seroprevalence of SARS-CoV-2 or SARS-CoV- 2-like\, and LASV\, moderate seroprevalence of Puumala virus and CHIKV\, a nd low prevalence of filoviruses. Very few dogs showed reactivity to the r ecombinant viral antigens\, suggesting that dogs can serve as sentinel ani mals.  The Mastomys and other rodent species showed high reactivities to these antigens\, indicating other species that are potential reservoirs of LASV and the presence of few circulating hantavirus and coronavirus-like viruses. Our results show that our assay has high specific sensitivity and is a cost-effective method for conducting serosurveillance studies in Lib eria.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:395@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230920T120000 DTEND;TZID=Pacific/Honolulu:20230920T130000 DTSTAMP:20230919T213405Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarviral -dynamics-and-host-immune-responses-to-sars-cov-2-infection-and-or-vaccina tion-alanna-tseng-phd SUMMARY:TRMD 690 Seminar:"Viral Dynamics and Host Immune Responses to SARS- CoV-2 Infection and/or Vaccination"\, Alanna Tseng\, PhD DESCRIPTION:\nIn Person &\; By Zoom\nContact corit@hawaii.edu for Zoom c onnection information\n\nAlanna Tseng\, Ph.D.\nInstructor\nDepartment of T ropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Sc hool of Medicine\nUniversity of Hawaiʻi at Mānoa\n\n\nThe last four yea rs of the COVID-19 pandemic have led to robust scientific advances\, inclu ding the early publication of the SARS-CoV-2 genome\, and the rapid develo pment of effective vaccines and diagnostic tools. However\, some knowledge gaps still remain regarding the understanding of natural and hybrid immun ity to SARS-CoV-2\, especially as newer Omicron subvariants emerge and upd ated COVID-19 vaccines become available. Furthermore\, few published studi es have focused on analyzing the SARS-CoV-2 variants circulating in Hawaii and the immune responses to SARS-CoV-2 infection and/or vaccination in mi nority populations. In this seminar\, I will share our preliminary results from a large SARS-CoV-2 genomic surveillance study and introduce several projects exploring the duration of infectious viral load and host immune r esponses to SARS-CoV-2 infection and/or vaccination in diverse cohorts fro m Hawaii. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:394@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230913T120000 DTEND;TZID=Pacific/Honolulu:20230913T130000 DTSTAMP:20230912T011518Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-trmd-690-semina rintensifying-cell-culture-processes-for-high-titer-virus-manufacturing-sv en-gobel SUMMARY:COBRE/TRMD 690 Seminar:"Intensifying Cell Culture Processes for Hig h Titer Virus Manufacturing"\, Sven Gobel DESCRIPTION:\nIn Person &\; By Zoom\nContact corit@hawaii.edu for meetin g passcode\n\nSven Göbel\, M.Sc.\nPh.D. Researcher\nMax-Planck Institute for Dynamics of Complex Technical Systems\nBioprocess Engineering Group\nM agdeburg\, Germany\n\n\nInnovations in viral vaccine and vector manufactur ing are crucial aspects for pandemic preparedness and required to meet eve r-rising global demands. Moreover\, emerging markets for gene therapies an d gene-modified cell therapies\, requiring high input doses\, further esca late the need for more efficient production processes. It becomes very cle ar that classical virus production capacities are not sufficient to meet t his increasing demand. Over the last years\, many promising bioreactor con cepts have been established and process options are now available to signi ficantly increase the yield in virus particle production. Current efforts to develop novel straightforward and intensified manufacturing technologie s for virus-based therapeutics\, which are reliable and can outcompete the benchmark set by prior state-of-the-art will be introduced and discussed. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:393@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230906T120000 DTEND;TZID=Pacific/Honolulu:20230906T130000 DTSTAMP:20230901T192310Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarrole- of-neutrophils-in-covid-19-juwon-park-phd SUMMARY:TRMD 690 Seminar:"Role of Neutrophils in COVID-19"\, Juwon Park\, P hD DESCRIPTION:\nIn Person &\; by Zoom\nZoom link available by request: ner urkar@hawaii.edu or corit@hawaii.edu\n\nJuwon Park\, PhD\nAssistant Profes sor\nDepartment of Tropical Medicine\, Medical Microbiology &\; Pharmac ology\nJohn A Burns School of Medicine\, University of Hawai‘i at Manoa\ n\n\nCoronavirus disease 2019 (COVID-19) is a novel\, viral-induced respir atory disease in which nearly one-third of individuals infected with COVID -19 have residual symptoms called Post-Acute Sequelae of SARS-CoV-2 infect ion (PASC). Neutrophils have a critical role in host defense against infec tion. Still\, uncontrolled or inappropriate neutrophil responses can contr ibute to immunopathology in infection\, inflammatory diseases\, and acute respiratory distress syndrome related to COVID-19. Literature to date demo nstrates compelling evidence of increased neutrophil counts and neutrophil extracellular traps (NETs) formation\, a type of neutrophils’ defense m echanism in the circulation and lungs of COVID-19 patients. Excessive NET formation has the potential to initiate and propagate inflammation and mic rothrombosis\, supporting the hypothesis that NETs induce organ damage dur ing COVID-19 infection that is linked to the development of prolonged symp toms. In this seminar\, I will share the current knowledge on neutrophils and COVID-19 pathogenesis\, particularly on NET formation. I will also int roduce a research project investigating the pathophysiological role of neu trophils in respiratory complications of COVID-19 patients. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:392@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230830T120000 DTEND;TZID=Pacific/Honolulu:20230830T130000 DTSTAMP:20230824T080738Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-special-one- health-presentation-infectious-disease-in-pacific-island-cetaceans SUMMARY:TRMD 690: Special One Health Presentation - "Infectious Disease in Pacific Island Cetaceans" DESCRIPTION:In-person location: UH Manoa Biomedical T208 or by Zoom\nMeetin g ID: 996 9907 3961\nContact coleflot@hawaii.edu for passcode\nKristi West \, PhD\nAssociate Researcher\nHawaii Institute of Marine Biology\nGraduate Faculty\, CTAHR Human Nutrition\, Food and Animal Sciences\n\n\nThe Unive rsity of Hawaiʻi Health and Stranding Lab investigates strandings of dolp hins and whales (cetaceans) across the central\, Western and South Pacific . Local Hawaiian cetacean populations include near-shore spinner dolphins\ , migratory humpback whales and approximately 18 other species of resident marine mammals that are recognized sentinels of ocean health. Stranding i nvestigations provide the only means to document causes of mortality in ce taceans and viral\, bacterial\, fungal and parasitic diseases that may pos e a threat to human health have been identified. Infectious disease findin gs include the discovery of two novel morbilliviruses from stranded Hawaii an cetaceans. An emerging disease\, beaked whale circovirus\, has been ide ntified in 10 new host species including whales stranded in Saipan and Ame rican Samoa. Toxoplasmosis represents yet another disease threat to Hawaii an cetaceans where felids serve as the definitive host and results from sp inner dolphins reveal a protozoal genotype described from feral pigs in Ha waiʻi. Brucellosis is a zoonotic disease that has been responsible for mo rtality in Hawaiian dolphins and whales. Marine mammal zoonoses will be di scussed in the context of a new partnership between the University of Hawa iʻi\, the Department of Land and Natural Resources\, the Department of He alth and federal stakeholders to increase capacity for zoonotic disease de tection and surveillance in the state. CATEGORIES:Seminar LOCATION:UH Manoa Biomedical Sciences Bldg.\, Rm T208\, 1960 East-West Rd.\ , Honolulu\, HI\, 96822\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1960 East-West Rd.\, Honolu lu\, HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=UH Manoa Biomed ical Sciences Bldg.\, Rm T208:geo:0,0 END:VEVENT BEGIN:VEVENT UID:391@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230824T120000 DTEND;TZID=Pacific/Honolulu:20230824T130000 DTSTAMP:20230823T194145Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=kuhner-bioreactor-sem inar-scaling-up-with-orbital-shaken-bioreactors SUMMARY:Kuhner Bioreactor Seminar: “Scaling Up with Orbital Shaken Biorea ctors” DESCRIPTION:Presenter: Mike Keebler\, Technical Representative for Kuhner S hakers\n\nTitle: “Scaling Up With Orbital Shaken Bioreactors\n\nMike Kee bler will be on-site to set up the SB-10X Bioreactor demo unit in the depa rtment.  In this seminar he will explain the technology and answer questi ons about the instrument and its use. LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:390@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230718T110000 DTEND;TZID=Pacific/Honolulu:20230718T120000 DTSTAMP:20230717T195113Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-seminaranalysis-of-dengue-and-zika-antibodies-among-a-cohort-of-p regnant-women-in-salvador-brazil-kaitlin-driesse-keegan-phd-candidate SUMMARY:Tropical Medicine PhD Defense Seminar:"Analysis of Dengue and Zika Antibodies Among a Cohort of Pregnant Women in Salvador\, Brazil"\, Kaitli n Driesse-Keegan\, PhD Candidate DESCRIPTION:Zoom Link: https://hawaii.zoom.us/j/92905534186?pwd=MENlbWJLYVR zdUxCNERIWGFFUFl4Zz09\nZoom ID:  929 0553 4186\nPasscode: TRMD2023\nCall in: (669) 900-6833\n\nKaitlin Driesse-Keegan\nTropical Medicine Ph.D. Cand idate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmaco logy\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa\n\n\ n\nDengue virus has been circulating in a hyperendemic pattern in Brazil f or decades and the introduction of Zika virus\, a closely related member o f the flavivirus genus\, into the Americas has complicated this situation. Zika virus has only recently begun to be viewed as a pathogen of signific ant concern. A dramatic increase in the incidence of microcephaly in North eastern Brazil was reported in late 2015\, coinciding with a large increas e in ZIKV infection. This unique pattern of microcephaly and other disabil ities linked to infection with Zika virus during pregnancy is known as Con genital Zika Syndrome (CZS). The pathogenesis driving this phenomenon is u nknown\, however\, due to the similarities between Zika and dengue viruses \, it is theorized that dengue virus-mediated immune enhancement in mother s may be a risk factor for the development of CZS in infants. As such\, it is important to further study the immune profiles of pregnant women infec ted with dengue and Zika viruses. Our research analyzes the antibody respo nse to dengue and Zika viruses among pregnant women during the 2015-16 Zik a outbreak in Salvador\, Brazil\, and characterizes cross-reactive antibod ies between dengue (DENV) and Zika (ZIKV). This study provides the unique ability to study the background levels of dengue virus immunity in pregnan t women in Northeast Brazil at the time of the ZIKV epidemic. Much is unkn own about the effect of prior dengue infection and its ability to confer p rotection or risk of enhancement of Zika virus infection\, especially duri ng pregnancy. We aim to better understand this relationship and how it cor relates to protection\, with the long-term goal of facilitating the develo pment of safe and effective DENV and ZIKV vaccines.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:389@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230512T143000 DTEND;TZID=Pacific/Honolulu:20230512T153000 DTSTAMP:20230502T195755Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-fin al-phd-defensecharacterizing-protective-antibody-responses-to-recombinant- ebola-virus-subunit-vaccines-in-non-human-primates-aquena-ball-phd-candida te SUMMARY:Tropical Medicine Final PhD Defense: "Characterizing Protective Ant ibody Responses to Recombinant Ebola Virus Subunit Vaccines in Non-Human P rimates”\, Aquena Ball\, PhD Candidate DESCRIPTION:\nIn-Person and By Zoom\nMeeting ID: 979 6297 5142\nPasscode: 3 06033\n \;\nAquena Ball\nPh.D. Candidate\nDepartment of Tropical Medic ine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medic ine\, University of Hawaii at Manoa\n\n\nEbola virus (EBOV) causes lethal hemorrhagic fevers with case fatality rates of up to 90%. Vaccination has been key to controlling outbreaks\; However\, due to limited stocks of app roved vaccines and stringent requirements of ultracold storage and distrib ution\, there is a need to continue developing new vaccines with more appr opriate product characteristics. Although all vaccine candidates use the s urface glycoprotein as the main antigen\, the method of protection induced by the EBOV glycoprotein remains unclear. We have developed a recombinant subunit vaccine that shows improved safety and thermostability profiles\, allowing easier deployment in endemic regions. Our vaccine has shown high efficacy in the gold standard non-human primate model of cynomolgus macaq ues\; however\, characterization of these protective antibody responses is ongoing with an aim to define a correlate of protection. We find that a c ombination of protective antibody qualities including GP targets\, neutral ization\, and effector function can be used to predict vaccine efficacy. A bility of antibodies to bind virus despite the presence of the mucin-like domain was also correlated with higher vaccine induced protection against EBOV with the majority of neutralizing and Fc effector functioning antibod ies binding regions beneath the mucin-like domain. Post-challenge kinetics are also a relatively unexplored aspect of vaccine induced protection. He re we find that rapid antibody responses are needed to confer protection i n sensitive NHP models and increases in antibody function later in infecti on\, likely stemming from IgM\, are not sufficient for protection in non-s urvivors. Currently\, mechanisms of protection do not have a clear consens us between vaccine platforms. Our findings will be used to guide further v accine development and provide insights into correlates of protection that are still unknown for Ebola and other filoviruses. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:388@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230503T120000 DTEND;TZID=Pacific/Honolulu:20230503T130000 DTSTAMP:20230502T194645Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-sero surveillance-of-emerging-and-re-emerging-viruses-in-liberia-in-human-and-a nimals-using-a-multiplex-bead-based-immunoassay-varney-kamara-phd-student SUMMARY:TRMD 690 Seminar: "Serosurveillance of Emerging and Re-emerging Vir uses in Liberia in Human and Animals using a Multiplex Bead-Based Immunoas say"\, Varney Kamara\, PhD Student DESCRIPTION:\nZoom ID: 979 6297 5142\nContact corit@hawaii.edu for passcode \n\nVarney Manipakeh Kamara\n\n\n\n\n\nPh.D. Student\nDepartment of Tropic al Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa\n\n\nUsing a one health approac h\, we have developed an in-house multiplex microsphere immunoassay to stu dy seroprevalence for antibodies against filovirus\, arenavirus\, coronavi rus\, alphavirus and bunyavirus antigens. This assay was employed in serum samples collected from humans\, rodents\, and dogs\, in four Liberian cou nties: Bong\, Lofa\, Nimba\, and Grand Bassa\, collectively known as Lassa virus (LASV) belt. Further\, using the same assay we tested human sera co llected throughout Liberia during the Liberian Demography Health Survey in 2021. Humans or animals with high reactivities to two or more antigens of the same pathogen were considered as a positive case. Spearman’s correl ation of positive samples showed high correlation between antigens of the same pathogen and cross-reactivity with antigens of different viruses from the same viral family. We detected a high seroprevalence of Chikungunya v irus\, and moderate seroprevalence of SARS-CoV-2 and LASV. The seroprevale nce of filovirus in this sample population was low. Interestingly\, simila r patterns were observed in dogs\, suggesting that canines can serve as se ntinel animals. In terms of rats\, we found high seroreactivities to both LASV glycoprotein and the nucleocapsid protein in the same animal\, and ac ross different species of rats\, indicating species other than the known M astomys rat may be potential reservoirs of LASV. Overall\, these results s how that the assay has high specificity\, sensitivity\, and is a cost-effe ctive method to conduct serosurveillance studies in Liberia.\n\n\n\n\n\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:387@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230426T120000 DTEND;TZID=Pacific/Honolulu:20230426T130000 DTSTAMP:20230424T211158Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarevalu ation-of-antiviral-activity-against-sars-cov-2-found-in-natural-hawaiian-m arine-extracts-mallory-wilson-ms-student SUMMARY:TRMD 690 Seminar:"Evaluation of Antiviral Activity Against SARS-CoV -2 Found in Natural Hawaiian Marine Extracts"\, Mallory Wilson\, MS Studen t DESCRIPTION: \;\nIn-Person &\; By Zoom\nZoom ID: 979 6297 5142\nEmai l corit@hawaii.edu for passcode\n\nMallory Wilson\, MPHTM\nM.S. Student\nD epartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJo hn A. Burns School of Medicine\nUniversity of Hawaii at Manoa\n\n\nWhile t he use of vaccines and social distance practices remain the best way to pr event the spread of SARS-CoV-2\, the management of acute COVID-19 requires other clinical therapeutic options. The use of antiviral therapies\, such as Pfizer’s Paxlovid and Merck’s Molnupiravir\, are now widely used. However\, both of these drugs are accompanied by the risk of liver and kid ney toxicity and there is concern regarding the potential development of d rug resistance. Thus\, there is an urgent need for more antiviral therapeu tic options that are safe\, effective and can be readily synthesized. Natu ral bioactive secondary metabolites are promising options for antiviral ac tivity. Marine environments serve as one source of these extracts and the island state of Hawai’i\, has a diverse repertoire of aquatic bioactive compounds. In this study we worked to identify novel marine extracts with antiviral activity against SARS-CoV-2. This study provides new insights in to the untapped resources that are natural marine extracts and their possi ble use as antiviral therapeutics. Further validation of these extracts wi ll focus on the characterization of mechanism of action in human primary c ells.\n \; CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:386@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230419T120000 DTEND;TZID=Pacific/Honolulu:20230419T130000 DTSTAMP:20230418T222227Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarneoge nin-1-as-a-novel-potential-predictive-biomarker-to-ameliorate-nsclc-immuno therapy-resistance-asmita-pandey-phd-student SUMMARY:TRMD 690 Seminar:Neogenin 1 as a Novel Potential Predictive Biomark er to Ameliorate NSCLC Immunotherapy Resistance"\, Asmita Pandey\, PhD Stu dent DESCRIPTION:\nIn-Person and By Zoom\nZoom ID: 979 6297 5142\nContact corit@ hawaii.edu for passcode\n \;\nAsmita Pandey\nPh.D. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Bur ns School of Medicine\nUniversity of Hawaii at Manoa\n\n\nNon-small cell l ung cancer (NSCLC) has a poor survival rate due to delayed diagnosis and t reatment resistance. Immunotherapies have advanced the NSCLC treatment at present\, however\, only a small fraction of patients respond to the thera py\, which necessitates to identify biomarkers that play a role in therapy resistance. From the list of anti-PD1/PD-L1 treatment resistance-associat ed biomarkers\, identified by studies done in our lab\, we discovered that Neogenin 1 (Neo1) shows relatively high expression in the NSCLC patients that leads to increased resistance. We hypothesized that high expression o f Neo1 in NSCLC patients downregulates PD1/PD-L1 expression leading to the treatment resistance. To validate this\, we plan to perform Neo1 manipula tion in NSCLC and jurkat T cells to measure the effect on PD1/PD-L1 expres sion\, following the investigation of the anti-PD1/PD-L1 treatment respons e in co-culture environment. In future\, our goal is to explore the mechan ism on how Neo1 overexpression regulates PD1/PD-L1 expression. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:385@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230417T153000 DTEND;TZID=Pacific/Honolulu:20230417T170000 DTSTAMP:20230417T062946Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=informational-webinar -for-one-health-certificate-program SUMMARY:Informational Webinar for One Health Certificate Program DESCRIPTION:\n\n\nZoom ID: 988 2877 7295\, Passcode: ONEHEALTH\nLearn about the new One Health Interdisciplinary Undergraduate Certificate Program to be offered for undergraduates and post-bacs starting in Fall 2023. The On e Health approach is dedicated to improving the lives of all species – h uman\, animal\, and plant – through the integration of human medicine\, veterinary medicine\, and environmental science. This webinar will provide an introduction to the One Health certificate curriculum and information on how to apply.\n\nThe One Health certificate will benefit students pursu ing a wide range of professions in human health (doctors\, nurses\, public health practitioners\, epidemiologists\, research scientists)\, animal he alth (veterinarians\, veterinary technicians\, agricultural workers)\, and environmental health (ecologists\, wildlife experts). Other One Health-re lated careers include science writing\, food safety\, disaster preparednes s\, global disease surveillance\, policy\, and sustainability practices.\n \nThis program is a partnership of the John A Burns School of Medicine\, t he Thompson School of Social Work &\; Public Health\, the School of Oce an and Earth Science and Technology\, and the College of Tropical Agricult ure and Human Resources.\n\nContact the UH Manoa One Health certificate pr ogram at onehlth@hawaii.edu to register.\n\nWebinar Agenda\n\n CATEGORIES:Informational Meeting END:VEVENT BEGIN:VEVENT UID:384@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230412T120000 DTEND;TZID=Pacific/Honolulu:20230412T130000 DTSTAMP:20230410T231344Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-prot eomic-studies-and-ingenuity-pathway-analysis-of-kawasaki-disease-immune-si gnatures-tatiana-aguilar-m-s-student SUMMARY:TRMD 690 Seminar: "Proteomic Studies and Ingenuity Pathway Analysis of Kawasaki Disease Immune Signatures\," Tatiana Aguilar\, M.S. Student DESCRIPTION:\nIn-Person &\; By Zoom\nZoom ID: 979 6297 5142\nContact cor it@hawaii.edu for passcode.\n\nTatiana Aguilar\nM.S. Student\nDepartment o f Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawai‘i at Mānoa\nKawasaki Disease ( KD) was first described by Dr. Tomisaku Kawasaki in 1967 and is now the le ading cause of acquired heart disease\, in the developed world. As the eti ology of KD remains unknown\, diagnosis relies on a trained clinician iden tifying the sequential appearance of a constellation of clinical signs aro und non-specific suppression of inflammation. A multitude of potential bio markers associated with KD\, the formation of KD-associated coronary arter y lesions (CAL)\, and resistance have been reported. These biomarkers incl ude a variety of immune factors relating to inflammation and immune cell r ecruitment\, tissue degradation\, and vascular changes. Discovering biomar kers associated with KD pathogenesis not only provides insight into the un derlying mechanisms of disease but also provides a molecular profile to be used in the clinic for diagnosis and prognostic purposes. The growing wor ld of integrated multi-omic research has provided a landscape to understan d upstream and downstream regulators and connecting networks. Using Qiagen ’s Ingenuity Pathway Analysis\, correlation between immune factors\, vas cular markers\, and clinical laboratory signs of inflammation compared aga inst a wide array of available literature.\n\n \; CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:383@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230405T120000 DTEND;TZID=Pacific/Honolulu:20230405T130000 DTSTAMP:20230404T015634Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarstudy -of-dengvaxia-recipients-from-mass-vaccination-program-in-philippines-yu-c hing-dai-phd-student SUMMARY:TRMD 690 Seminar:"Study of Dengvaxia recipients from mass vaccinati on program in Philippines"\, Yu-Ching Dai\, PhD Student DESCRIPTION:\n\nIn-Person &\; By Zoom\nZoom ID: 979 6297 5142\nContact c orit@hawaii.edu for passcode.\n\nYu-Ching Dai\nPh.D. Student\nDepartment o f Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawai‘i at Mānoa\nDengue virus (DENV ) is the leading cause of mosquito-borne viral diseases in humans. Dengvax ia (CYD Vaccine)\, the first licensed dengue vaccine\, was recommended for DENV-seropositive individuals aged 9-45 years. In Philippines\, Dengvaxia vaccination was launched in 2016 with >\;830\,000 children receiving at least one dose. As most Dengvaxia recipients were not pre-screened\, an a ssay that can reliably determine prior DENV serostatus to assess Dengvaxia vaccine’s long-term safety and effectiveness is critically needed. In t his study\, we evaluated our DENV1-4 NS1 IgG ELISA and explored its applic ation to 199 participants from the fever surveillance program in Philippin es. The sensitivity/specificity of the assay was 97.0/99.4%\, which was hi gher than those reported for pre-vaccination screening. A significantly hi gher rate of symptomatic DENV breakthrough infection was found among previ ous DENV-naïve than previous DENV-immune Dengvaxia recipients\, demonstra ting the feasibility of the assay and algorithms in the real world. The al gorithms based on our ELISA can determine prior DENV serostatus among Deng vaxia recipients not only during non-dengue but also DENV breakthrough inf ection to assess the safety and effectiveness of Dengvaxia in the post-lic ensure period.\n\n \;\n\n\n\nUniversity of Hawaii at Manoa\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:382@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230405T120000 DTEND;TZID=Pacific/Honolulu:20230405T130000 DTSTAMP:20230403T234556Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-wedn esday-april-5-2023-1200-pm-100-pm-hst SUMMARY:TRMD 690 Seminar Wednesday\, April 5\, 2023 @ 12:00 PM - 1:00 PM H ST DESCRIPTION:Department of Tropical Medicine\, Medical\nMicrobiology and Pha rmacology\n\nSEMINAR\nTRMD 690\nStudy of Dengvaxia recipients from mass va ccination program in Philippines\nDengue virus (DENV) is the leading cause of mosquito-borne viral diseases in humans.\nDengvaxia (CYD Vaccine)\, th e first licensed dengue vaccine\, was recommended for\nDENV-seropositive i ndividuals aged 9-45 years. In Philippines\, Dengvaxia vaccination\nwas la unched in 2016 with >\;830\,000 children receiving at least one dose. As most\nDengvaxia recipients were not pre-screened\, an assay that can reli ably determine prior\nDENV serostatus to assess Dengvaxia vaccine’s long -term safety and effectiveness is\ncritically needed. In this study\, we e valuated our DENV1-4 NS1 IgG ELISA and explored\nits application to 199 pa rticipants from the fever surveillance program in Philippines.\nThe sensit ivity/specificity of the assay was 97.0/99.4%\, which was higher than thos e\nreported for pre-vaccination screening. A significantly higher rate of symptomatic DENV\nbreakthrough infection was found among previous DENV-na ïve than previous DENV-immune Dengvaxia recipients\, demonstrating the fe asibility of the assay and algorithms in the real world. The algorithms ba sed on our ELISA can determine prior DENV serostatus among Dengvaxia recip ients not only during non-dengue but also DENV breakthrough infection to a ssess the safety and effectiveness of Dengvaxia in the post-licensure peri od.\nYu-Ching Dai\nPh.D Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, Univers ity of Hawaii at Manoa\nWednesday\, April 05\, 2023\n12:00 – 1:00 P.M. H ST\nJABSOM\, Kakaako Campus\nMedical Education Building Auditorium (Room 3 15)\nZoom Details\nLink: https://zoom.us/j/97962975142?pwd=aFdJZmhrbjdDOGQ 2UFZHZTYyeDhUZz09\nMeeting ID: 979 6297 5142\nContact corit@hawaii.edu for Passcode END:VEVENT BEGIN:VEVENT UID:380@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230322T120000 DTEND;TZID=Pacific/Honolulu:20230322T130000 DTSTAMP:20230322T071404Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarrsv-v accine-update-renn-silve-salomon-ms-student SUMMARY:TRMD 690 Seminar:"RSV Vaccine Update"\, Renn Silve Salomon\, MS Stu dent DESCRIPTION:\nIn Person and By Zoom\n Zoom ID: 979 6297 5142\nContact neru rkar@hawaii.edu for passcode\n\nRenn Silve Salomon\nM.S. Student\nDepartme nt of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. B urns School of Medicine\, University of Hawaii at Manoa\n\n\nRespiratory s yncytial virus (RSV) is the most important cause of viral lower respirator y tract illness (LRI) in infants and children worldwide. While the burden is highest among the pediatric population\, the elderly and immunocompromi sed are also at risk of severe infection and high rate of mortality compar able to that of influenza. Along with COVID-19 and Influenza\, RSV has cau sed increased cases of respiratory infection in all age groups\, which cou ld potentially result to "tripledemic." There are no antivirals specific f or RSV and only one approved monoclonal antibody (Palivizumab) for prophyl actic usage in high-risk infants. Although there are no FDA approved vacci nes\, there are currently seven vaccine candidates in Phase 3 trials. Two RSV subunit vaccine candidates manufactured by Pfizer and GlaxoSmithKline\ , have recently received FDA advisory recommendations for use in individua ls over 65 years. This seminar will include a brief overview of RSV virolo gy and the current landscape of monoclonal treatments and vaccines in late -stage clinical trials. The phase 3 results of the two RSV vaccines recomm ended for approval will be discussed.\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:379@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230308T120000 DTEND;TZID=Pacific/Honolulu:20230308T130000 DTSTAMP:20230307T233957Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminara-mea ndering-journey-my-experience-from-graduate-school-to-early-stage-arboviru s-researcher-ngu-abanda-centre-pasteur-of-cameroon SUMMARY:TRMD 690 Seminar:"A Meandering Journey: My Experience from Graduate School to Early-stage Arbovirus Researcher\," Ngu Abanda\, Centre Pasteur of Cameroon DESCRIPTION:\nIn-Person and By Zoom\nZoom Meeting ID: 979 6297 5142\nContac t corit@hawaii.edu for passcode\n\nNgu Abanda\, Ph.D.\nThrasher Early Care er Researcher\nNorthern Pacific Global Health Fellow\nResearch Scientist\,  Centre Pasteur of Cameroon\nYaoundé\, Cameroon\n\n\n\nIn 2017\, I was a warded a doctoral degree from the Department of Tropical Medicine\, Medica l Microbiology\, and Pharmacology (DTMMMP) of the University of Hawaii at Manoa. Since 2020\, I have been a Research Scientist at the Pasteur Centre in Cameroon and a Lead Scientist for the WHO Yellow Fever Regional Refere nce Laboratory in Central Africa. I often get asked a lot about what my jo b entails and how I got there. In today’s seminar\, I will tell you abou t my journey as a student in the DTMMMP to my current position at the Cent re Pasteur of Cameroon. Further\, I will highlight some of our ongoing res earch projects on arboviruses. The research topics will include\, 1) The T hrasher/NPGH study "An assessment of humoral and cellular immunity against yellow fever in HIV+ and HIV- children vaccinated during infancy”\; 2) The CREID Pilot project "Reconstructing historical patterns of arbovirus t ransmission in Cameroon using serological data”\; 3) GSK Pilot project " Perception\, practices\, severity\, and immune response to dengue in a mal aria endemic area”\; and 4) Grand Challenge Canada project "An early war ning system for the surveillance of mosquito-borne viruses." CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:378@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230301T120000 DTEND;TZID=Pacific/Honolulu:20230301T130000 DTSTAMP:20230228T001708Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-pote ntial-pharmacological-inhibitors-for-the-treatment-of-flavivirus-infection s-bryan-rios-m-s-student SUMMARY:TRMD 690 Seminar: "Potential Pharmacological Inhibitors for the Tre atment of Flavivirus Infections\," Bryan Rios\, M.S. Student DESCRIPTION:In recent years\, flaviviruses such as WNV\, DENV\, and ZIKV ha ve emerged\nas significant global public health threats due to ineffective therapeutics.\nTherefore\, repurposing FDA-approved drugs is a promising strategy for\nrapid drug development. This study aimed to identify target- specific\ninhibitors that could effectively disrupt flavivirus replication and survival by\nscreening 24 FDA-approved drugs against WNV and DENV inf ection in\nHEK293T and Vero E6 cells. To evaluate the efficacy of each dru g\, we\nassessed their impact on viral RNA replication\, viral protein syn thesis\, viral\nplaque production\, and cellular cytotoxicity. The study i dentified several\ndrugs that exhibited potent antiviral activity against WNV and DENV\, \ndemonstrating the potential of drug repurposing as a viab le approach for flavivirus treatment. CATEGORIES:Seminar LOCATION:Medical Education Building Room 315\, John A. Burns School of Medi cine\,651\, Ilalo Street\, \, Honolulu\,\, Hawaii\, 96813\, United States GEO:21.2965022;-157.86368019999998 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=John A. Burns School of Med icine\,651\, Ilalo Street\, \, Honolulu\,\, Hawaii\, 96813\, United States ;X-APPLE-RADIUS=100;X-TITLE=Medical Education Building Room 315:geo:21.296 5022,-157.86368019999998 END:VEVENT BEGIN:VEVENT UID:377@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230222T120000 DTEND;TZID=Pacific/Honolulu:20230222T130000 DTSTAMP:20230222T195207Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690covid-19-rela ted-hospitalization-and-outcomes-among-native-hawaiians-and-pacific-island ers-chelsea-nicholas-ms-student SUMMARY:TRMD 690:"COVID-19-Related Hospitalization and Outcomes Among Nativ e Hawaiians and Pacific Islanders"\, Chelsea Nicholas\, MS Student DESCRIPTION:Zoom Seminar Only\nMeeting ID: 979 6297 5142\nContact corit@haw aii.edu for passcode\n\nChelsea Nicholas\, M.S.\nM.S. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burn s School of Medicine\nUniversity of Hawaii at Manoa\n\n\n\nRace and ethnic ity can serve as a marker for underlying systemic and structural inequitie s that steer health disparities. Associations of risk factors with COVID-1 9 outcomes have been shown to differ by racial and ethnic groups. Hence\, disaggregated race data can unveil health disparities across subpopulation s. In Hawaii\, Native Hawaiians and Other Pacific Islanders (NHOPI) have b een the most overrepresented in COVID-19 cases\, hospitalizations\, and de aths since March 2020. The majority of NHOPI present with many pre-existin g health conditions that are known to significantly increase one’s risk of severe COVID-19 illness and death. Yet\, risk-adjusted differences in C OVID-19 outcomes among patients of differing ethnicity and race categories are not well characterized. To achieve this\, we investigated the associa tion of race and ethnicity with comorbidities and mortality among NHOPI pa tients with COVID-19 in Hawaii’s largest healthcare system from March 20 20 to May 2022. These findings will assist in current efforts to tailor CO VID-19 health information\, treatment\, and prevention strategies for unde rserved populations. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:374@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230216T120000 DTEND;TZID=Pacific/Honolulu:20230216T130000 DTSTAMP:20230201T075232Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-dis sertation-defensevirologic-and-bioinformatic-analysis-of-sars-cov-2-david- maison-phd-candidate SUMMARY:Tropical Medicine Dissertation Defense:"Virologic and Bioinformatic Analysis of SARS-CoV-2"\, David Maison\, PhD Candidate DESCRIPTION:In Person &\; By Zoom\nZoom Meeting ID: 968 6171 5430\nConta ct jogata22@hawaii.edu for passcode\n\nDavid Maison\, M.S.\nPh.D. Candidat e\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology \nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\n This work combines virology\, bioinformatics\, and algorithms to study SAR S-CoV-2 and COVID-19. The study focuses on Hawaiʻi and involves sequencin g the S gene\, isolating the virus\, developing a whole-genome sequencing workflow\, comparing predicted B and T cell epitopes\, evaluating quaranti ne effectiveness\, and applying precision public health genomics. The resu lts provide a foundation for understanding the COVID-19 pandemic globally and in Hawaiʻi\, showing multiple introductions of the virus in Hawaiʻi\ , the P681H substitution emerging worldwide\, the need for vaccine redesig n\, and the origin of variants in Hawaiʻi. The work also demonstrates tha t quarantine was effective and develops an algorithm to monitor virus evol ution and emergence for vaccine redesign. This work provides important dat a and insights into the COVID-19 pandemic and will help in future pandemic preparedness. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:376@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230215T120000 DTEND;TZID=Pacific/Honolulu:20230215T130000 DTSTAMP:20230215T072112Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminaradvan ces-in-multicolor-panel-design-to-analyze-immune-responses-to-pathogens-ra vi-hingoriana-phd-bd-biosciences SUMMARY:TRMD 690 Seminar:"Advances in multicolor panel design to analyze im mune responses to pathogens"\, Ravi Hingoriana\, PhD\, BD Biosciences DESCRIPTION:Zoom Webinar\nZoom ID: 979 6297 5142\nContact jogata22@hawaii.e du for passcode\n\nRavi Hingorani\, Ph.D.\, S.C.Y.A.\nHigh Dimensional Bio logy Scientific Support\nBD Biosciences\nSan Diego\, California\, USA\n\n\ n\nAs biology advances\, the need for deep and broad profiling of cell pop ulations is becoming ever more important. Quality flow cytometry data star ts with proper panel design. Fluorochrome choices\, instrument configurati ons/setup\, and knowledge of the biology being studied are important facto rs\; with a good panel defined by its ability to resolve populations of in terest. Matching bright fluorochromes to dim markers\, and the ability to spread markers across multiple lasers\, can minimize spectral overlap and maximize population resolution. Principles of panel design are equally app licable to higher order flow cytometry panels on high-parameter instrument ation. To truly maximize the potential of your flow cytometry research\, t rusted technologies can help you achieve success in experimental outcomes. Instruments with configurations that minimize compensation\, a wide selec tion of high- performing reagents\, combined with online tools such as the panel designer\, are key components to success. This talk will provide in sights to help you simplify panel design so you can confidently unlock the full potential of flow cytometry in your research. Round table discussion s afterwards – Please bring your questions and proposed panels! CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:375@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230208T120000 DTEND;TZID=Pacific/Honolulu:20230208T130000 DTSTAMP:20230208T004523Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarepito pe-resolved-profiling-of-the-antibody-response-to-sars-cov-2-infection-and -vaccination-jason-t-ladner-ph-d-northern-arizona-university SUMMARY:TRMD 690 Seminar:"Epitope-resolved profiling of the antibody respon se to SARS-CoV-2 infection and vaccination"\, Jason T. Ladner\, Ph.D.\, No rthern Arizona University DESCRIPTION:Zoom ID: 979 6297 5142\n\nContact jogata22@hawaii.edu for passc ode\n\nJason T. Ladner\, Ph.D.\nAssistant Professor\nThe Pathogen and Micr obiome Institute\nNorthern Arizona University\nFlagstaff\, Arizona\, USA\n \n\n\nPepSeq is an in vitro platform for building and conducting highly mu ltiplexed serology assays that are sample sparing and can simultaneously q uantify antibody binding against 100\,000s of peptide antigens. We have us ed PepSeq to obtain an epitope-resolved view of antibody responses against SARS-CoV-2 infection and vaccination. Among the immunodominant epitopes\, we identified two highly conserved regions of the Spike glycoprotein\, wh ich elicit antibodies that often cross-recognize multiple coronaviruses an d therefore have the potential to mediate broadly neutralizing protection. Antibody responses against these conserved epitopes appear rapidly follow ing SARS-CoV-2 infection and vaccination but evolve over time to gain spec ificity to SARS-CoV-2. Dr. Ladner will be presenting an overview of the Pe pSeq platform for highly multiplexed serology\, as well as the application of PepSeq for understanding the human antibody response to SARS-CoV-2.\n\ n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:373@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230201T120000 DTEND;TZID=Pacific/Honolulu:20230201T130000 DTSTAMP:20230131T020727Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarbioma rkers-and-novel-nanobody-therapeutic-approaches-for-treatment-of-neurodege neration-and-viral-diseases-menish-bhyomia-phd-henry-jackson-foundation SUMMARY:TRMD 690 Seminar:"Biomarkers and novel nanobody therapeutic approac hes for treatment of neurodegeneration and viral diseases"\, Manish Bhomia \, PhD\, Henry Jackson Foundation DESCRIPTION:Zoom ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcod e\n\nManish Bhomia\, Ph.D.\nSenior Scientist\nHenry Jackson Foundation\nAs sistant Professor\nUniformed Services University of the Health Sciences\nB ethesda\, Maryland\, US\n\n\n\nTraumatic brain injury (TBI) is defined as an injury to the brain by external forces which can lead to cellular damag e and disruption of the normal central nervous system functions. Worldwide \, TBI is considered as one of the major causes of disability and death. B iomarkers can help identifying the TBI early and can help in better manage ment and care of the patient. MicroRNAs are small non-coding RNA molecules that are easy to detect and stable in the peripheral circulation. Our stu dies have identified miRNAs as specific and sensitive biomarkers to detect TBI in both TBI and sports concussions. In addition\, currently there are no FDA approved treatment of TBI. We are working on a novel nanobody-base d immunotherapy development for treatment of traumatic brain injury. Due t o their small size and high specificity\, nanobodies are an attractive too l to develop novel immunotherapies for neurodegenerative diseases and vira l infections. Our laboratory is also working on development of similar the rapy for severe dengue infection. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:372@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230125T120000 DTEND;TZID=Pacific/Honolulu:20230125T130000 DTSTAMP:20230121T094648Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-seve re-malaria-and-traumatic-brain-injury-neurocognitive-consequences-in-child hood-survivors-of-two-unrelated-but-common-cns-injury-disorders-dibyadyuti -data-phd-indiana-univ SUMMARY:TRMD 690 Seminar: "Severe malaria and traumatic brain injury: Neuro cognitive consequences in childhood survivors of two unrelated but common CNS injury disorders"\, Dibyadyuti Data\, PhD\, Indiana University School of Medicine DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcode\n\nDibyadyuti Datta\, M.S.\, Ph.D.\nAssistant Professor of Pedia trics\nDepartment of Pediatrics\, Ryan White Center for Pediatric Infectio us Diseases &\; Global Health\nIndiana University School of Medicine\nI ndianapolis\, Indiana\, US\n\n\n\nNeurocognitive impairment (NCI) is a com mon complication of two seemingly unrelated nervous system disorders: cere bral malaria (CM) and traumatic brain injury (TBI). In CM\, mortality rema ins close to 20%\; in surviving children and 25% suffer persistent NCI. CM also puts a high disease burden on African nations. TBI is a major cause of mortality and neurodisability worldwide\, with >\;50% cases seen in y outh in low-middle income countries (LMIC). The pathophysiology’s of CM and TBI have overlapping features including injury to the brain’s microv asculature and associated metabolic and blood-brain barrier dysfunction. T echnological advances have identified circulating brain-specific biomarker s for predicting patient outcomes. However\, there are limited studies foc used on CM and none on TBI in LMIC. Understanding the knowledge gap is a k ey first step to facilitate research into interventions to prevent or redu ce NCI. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:371@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20230111T120000 DTEND;TZID=Pacific/Honolulu:20230111T130000 DTSTAMP:20230110T012933Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-reco mbinant-subunit-vaccine-development-next-generation-vaccines-david-clement s-ms-hawaii-biotech SUMMARY:TRMD 690 Seminar:” Recombinant Subunit Vaccine Development – Ne xt Generation Vaccines”\, David Clements\, MS\, Hawaii Biotech DESCRIPTION:In-Person &\; By Zoom\nZoom Meeting ID: 979 6297 5142\nConta ct jogata22@hawaii.edu for passcode\n\nDavid Clements\, M.S.\nDirector of Vaccine Research and Development\, Hawaii Biotech\nHonolulu\, Hawaii\n\n\n Emerging and reemerging infectious disease threats have become an almost a nnual event over the last two decades.  The SARS-CoV-2 pandemic has furth er highlighted these threats.  This trend is unlikely to subside due to t he complex dynamics of increased urbanization\, aging of populations\, inc reased travel\, climate change\, and ecological shifts in vector\, pathoge n\, and human populations.  Consequently\, it is clear that reactive appr oaches to combating these threats are problematic and there is a need for more proactive approaches. The development of platform technologies that help to reduce cost of manufacturing and increase the speed of development are important.  Hawaii Biotech has developed a vaccine platform that all ows for multiple vaccine targets to be addressed.  The platform integrate s several aspects that provides the opportunity to produce next generation vaccines.  These aspects include well-defined recombinant protein vaccin e antigens that maintain proper conformation and preserve important neutra lizing epitopes\, a stable insect cell-based system\, an established cGMP manufacturing platform\, and the use of a state-of-the-art adjuvants. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:370@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221219T110000 DTEND;TZID=Pacific/Honolulu:20221219T120000 DTSTAMP:20221209T180853Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminarsars-cov-2-infection-and-persistence-throughout-the-human-body-a nd-brain-daniel-s-chertow-national-institutes-of-health-clinical-center SUMMARY:COBRE Tropical Medicine Seminar:"SARS-CoV-2 Infection and Persisten ce throughout the Human Body and Brain"\, Daniel S. Chertow\, National Ins titutes of Health Clinical Center DESCRIPTION:In Person or By Zoom\nZoom ID:  968 6747 7307\nContact jogata2 2@hawaii.edu for passcode\n\nDaniel S. Chertow\, M.D.\, M.P.H.\nTenure-Tra ck Investigator\, Critical Care Medicine Department\nNational Institutes o f Health Clinical Center\nLaboratory of Immunoregulation\, NIAID\nBethesda \, Maryland\n\n\n\nCOVID-19 is known to cause multi-organ dysfunction duri ng acute infection with SARS-CoV-2\, with some patients experiencing prolo nged symptoms. However\, the burden of infection outside the respiratory t ract and time to viral clearance is not well characterized\, particularly in the brain. We carried out complete autopsies on 44 patients who died wi th COVID-19\, with extensive sampling of the central nervous system in 11 of these patients\, to map and quantify the distribution\, replication\, a nd cell-type specificity of SARS-CoV-2. We show that SARS-CoV-2 is widely distributed\, and that virus replication is present in multiple respirator y and non-respiratory tissues\, including the brain\, early in infection. Further\, we detected persistent SARS-CoV-2 RNA in multiple anatomic sites \, including throughout the brain\, as late as 230 days following symptom onset. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:369@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221207T120000 DTEND;TZID=Pacific/Honolulu:20221207T130000 DTSTAMP:20221202T230626Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-inte r-relationships-between-sars-cov-2-and-common-cold-coronavirus-antibody-re sponses-among-children-diagnosed-with-kawasaki-disease-prior-to-and-during -the-covid-19-pandemi SUMMARY:TRMD 690 Seminar:”Inter-relationships between SARS-CoV-2 and Comm on Cold Coronavirus antibody responses among children diagnosed with Kawas aki disease prior to and during the COVID-19 pandemic”\, Lauren Ching\, PhD Student DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcode\n\nLauren Ching\nPh.D. student\nDepartment of Tropical Medicine\ , Medical Microbiology and Pharmacology \nJohn A. Burns School of Medicine \, University of Hawaii at Manoa\n\n\nClinical similarities between Kawasa ki disease (KD) and Multi-system inflammatory syndrome in children (MIC-C) following SARS-CoV-2 exposure have led some to speculate if cross-coronav irus immunity may explain their shared presentation. KD presents as an acu te systemic vasculitis in pediatric populations and is the leading cause o f acquired heart disease in the developed world. Although the etiology of KD remains unknown\, epidemiological patterns of the disease suggests an i nfectious agent causing an exaggerated immune response in genetically susc eptible hosts\, with most infected children experiencing an asymptomatic i nfection. The rarity of MIS-C\, early observation that children seem to ex perience a mild course of SARS-CoV-2 infections (as compared to adults)\, and shared clinical presentation of acute inflammatory disease in children lead clinicians to speculate that they were the same disease. In this stu dy\, we evaluated the human coronavirus antibody repertoire (pandemic coro naviruses SARS-CoV-2\, SARS-CoV\, MERS-CoV\, and common cold corona viruse s HCoV-229E\, HCoV-OC43\, HCoV-NL63\, and HCoV-HUK1) in a cohort of childr en diagnosed with KD both prior to and during the COVID-19 pandemic\, foll owing each child through acute\, sub-acute\, and convalescent phases of th e KD. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:368@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221130T120000 DTEND;TZID=Pacific/Honolulu:20221130T130000 DTSTAMP:20221129T001611Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarvirol ogic-and-bioinformatic-analysis-of-sars-cov-2-david-maison-phd-student SUMMARY:TRMD 690 Seminar:"Virologic and Bioinformatic Analysis of SARS-CoV- 2"\, David Maison\, PhD Student DESCRIPTION:In Person and By Zoom\nZoom ID: 979 6297 5142\nContact jogata22 @hawaii.edu for passcode\n\nDavid P. Mason\nPh.D. Student\nDepartment of T ropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Sc hool of Medicine\nUniversity of Hawaii at Manoa\n\n\n\nSevere acute respir atory coronavirus 2 (SARS-CoV-2)\, the causative agent of Coronavirus Dise ase 2019 (COVID-19)\, has been the scourge of the world for the past three years. Worldwide\, over 619 million cases of COVID-19 have resulted in ov er 6.5 million deaths. Hawaii has not been spared from this pandemic\, wit h more than 349\,000 cases of COVID-19 and 1\,691 deaths\, with considerab le caseloads among ethnic populations. This work combines virology\, bioin formatics\, and algorithms to discover new mutations\, evaluate COVID-19 p ublic policy\, and facilitate the standardization of next-generation vacci ne design and variant classification. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:367@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221123T120000 DTEND;TZID=Pacific/Honolulu:20221123T130000 DTSTAMP:20221122T024831Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-ms-t hesis-defense-development-of-a-chaotrope-modified-multiplex-immunoassay-to -measure-antibody-avidity-in-sars-cov-2-naive-and-convalescent-vaccinees-t roy-odo-ms-candidate SUMMARY:TRMD 690 Seminar & MS Thesis Defense: "Development of a Chaotrope-M odified Multiplex Immunoassay to Measure Antibody Avidity in SARS-CoV-2 Na ïve and Convalescent Vaccinees"\, Troy Odo\, MS Candidate DESCRIPTION:In Person &\; By Zoom\nZoom ID: 979 6297 5142\nContact jogat a22@hawaii.edu for passcode\n\nTroy Odo\n\nM.S. Student\n\nDepartment of T ropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Sc hool of Medicine\nUniversity of Hawaii at Manoa\n\n\nOver the past two yea rs\, SARS-CoV-2 has had a devastating impact across the world. Despite the historic success of the multiple SARS-CoV-2 vaccines\, additional researc h is needed to further understand the underlying mechanisms of protection. While many studies focus primarily on antibody neutralization titers\, an other aspect of humoral immunity that is often overlooked is antibody avid ity. Avidity\, the total binding strength of all interactions between an a ntibody and antigen\, is important to consider in the context of vaccinati on because it provides an important measure of antibody maturation and dev elopment. This study will focus on the development of a chaotrope-modified multiplex immunoassay that can be used to measure SARS-CoV-2 antibody avi dity. Additionally\, we will use this assay to measure longitudinal sera c ollected from SARS-CoV-2 naïve and convalescent vaccinees to investigate the relationship between natural infection and vaccination. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:366@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221116T120000 DTEND;TZID=Pacific/Honolulu:20221116T130000 DTSTAMP:20221116T000844Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarplate let-and-neutrophil-interaction-in-chronic-hiv-natalie-subie-ms-student SUMMARY:TRMD 690 Seminar:"Platelet and Neutrophil Interaction in Chronic HI V"\, Natalie Subie\, MS Student DESCRIPTION:In Person or by Zoom\nMeeting ID: 979 6297 5142\nContact jogata 22@hawaii.edu for passcode.\n\nNatalie Subia\nMS Student\nDepartment of Tr opical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Sch ool of Medicine\, the University of Hawaii at Manoa\n\n\n\nA highly effect ive combination of anti-retroviral therapy (cART) reduces HIV infections t o manageable chronic diseases. Still\, the persistence of HIV in tissues a nd cellular reservoirs remains an obstacle to achieving sustained virologi c suppression. Viral reservoir persistence is characterized as chronic\, l ow-grade viral replication\, contributing to developing non-AIDS co-morbid ities\, including cardiovascular disease (CVD)\, that eventually could lea d to death. Multiple factors may explain the increased burden of non-AIDS comorbidities\, such as high incidence of traditional cardiovascular risk factors\, persistent HIV-related inflammation\, and side effects of long-t erm cART. Another considerable contributor to these co-morbidities is plat elet-neutrophilinteraction. However\, there is not a very well-known under standing of the pathological mechanisms of their interaction in HIV. There fore\, this study determines two key research aims\, deliberately revealin g a potential crosstalk mechanism between inflammation and coagulation thr ough neutrophil and platelet interaction. Multiplex assays and gelatin zym ography will be used to quantify markers for prothrombotic and neutrophil activation in plasma collected from HIV+ and HIV- individuals. I will furt her determine if there is an association between these markers and activat ed platelet and neutrophil counts and platelet and neutrophil aggregation (PNA) in HIV+ individuals. This study will provide evidence of the involve ment of platelets and neutrophils in shaping inflammation and thrombosis i n HIV\, and hopefully\, my study will help to find strategies to prevent n on-AIDS comorbidities CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:358@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221112T180000 DTEND;TZID=Pacific/Honolulu:20221112T210000 DTSTAMP:20221018T081916Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=save-the-date-hi-asm- spring-meeting SUMMARY:HI-ASM SPRING MEETING DESCRIPTION:Hawaii Branch of the American Society for Microbiology (HI-ASM) \n2022 Fall Meeting\nSaturday 12 November\, 2022\nPagoda Floating Restaura nt\, International Ballroom\n\n\n\nSeminar Title:\n"Factors Responsible fo r the Development of Pulmonary Post-Acute Sequelae of SARS-CoV-2 Infection in Hawaii"\n\n\n\nKeynote speakers:\nDominic Chow\, MD\, PhD\, MPH\nProfe ssor of Medicine\, Clinical Professor of Pediatrics\nHawai‘i Center for AIDS\nJohn A Burns School of Medicine\nGehan Devendra\, MD\nPulmonary Crit ical Care Medicine\nQueenʻs University Medical Group\n\nMeeting Flyer CATEGORIES:Conference LOCATION:Pagoda Floating Restaurant\, 1525 Rycroft St.\, Honolulu\, HI\, 96 814\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1525 Rycroft St.\, Honolulu \, HI\, 96814\, United States;X-APPLE-RADIUS=100;X-TITLE=Pagoda Floating R estaurant:geo:0,0 END:VEVENT BEGIN:VEVENT UID:365@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221109T120000 DTEND;TZID=Pacific/Honolulu:20221109T130000 DTSTAMP:20221107T234620Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-broa d-acting-therapeutics-for-snake-spider-and-marine-envenomation-using-candi date-inhibitors-of-highly-conserved-venom-toxins-raechel-kadler-phd-studen t SUMMARY:TRMD 690 Seminar: “Broad Acting Therapeutics for Snake-\, Spider- \, and Marine-Envenomation using Candidate Inhibitors of Highly Conserved Venom Toxins”\, Raechel Kadler\, PhD Student DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcode\n\nRaechel Kadler\nPh.D. Student\nDepartment of Tropical Medicin e\, Medical Microbiology and Pharmacology \nJohn A. Burns School of Medici ne\, University of Hawaii at Manoa\n\n\nAnnually\, there are millions of s nake-\, spider-\, scorpion-\, hymenopteran- and jellyfish-envenomations th at result in both death and injury. The availability of healthcare and of useful therapeutics\, such as antivenoms\, represent critical challenges t o optimal outcomes and survival. Available antivenoms are expensive\, requ ire cold-chain storage\, and have a limited shelf life. Morbidity can resu lt in life-long care requirements and the associated costs. Importantly\, most of these incidents occur in remote environments where it is difficult to identify the culpable animal as well as obtain therapeutics in a timel y manner. While venom composition\, a complex mixture of proteins\, enzyme s\, lipids and small molecules\, vary across species\, there are essential components that have been conserved across evolution. These components\, while necessary for prey capture and digestion\, result in common pathophy siology in the victim. These include tissue necrosis\, coagulopathies\, po rin-based sequalae such as pulseless electrical activity and acute cardiop ulmonary collapse. Inhibitors of these venom components represent strong c andidates for therapeutics.  Specifically\, we will assess the efficacy o f inhibitors to lipase\, metalloproteinase and pore-forming enzyme activit y in both snake and cubozoan venoms. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:364@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221102T120000 DTEND;TZID=Pacific/Honolulu:20221102T130000 DTSTAMP:20221102T185837Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarthe-i mpact-of-covid-19-on-the-circulation-of-respiratory-viruses-among-united-s tates-military-beneficiaries-rachael-downham-phd-student SUMMARY:TRMD 690 Seminar:"The Impact of COVID-19 on the Circulation of Resp iratory Viruses Among United States Military Beneficiaries..."\, Rachael D ownham\, PhD Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcod e\n\n"The Impact of COVID-19 on the Circulation of Respiratory Viruses Amo ng United States Military Beneficiaries at a Medical Treatment Facility in Hawai’i with Genomic Surveillance of SARS-CoV-2 in a Pacific Military P opulation"\nRachael L. Downham\nPh.D. Student\nDepartment of Tropical Medi cine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medi cine\nUniversity of Hawaii at Manoa\n\n\n\nViral respiratory tract infecti ons are a leading cause of morbidity worldwide. Hawaii implemented signifi cant public health measures resulting in one of the lowest COVID-19 rates in the nation. This study aimed to evaluate the prevalence and etiology of respiratory viral infections during the ongoing COVID-19 pandemic among m ilitary health system beneficiaries on Oahu\, Hawaii. We retrospectively a nalyzed respiratory viral specimens collected from January 2020 to Februar y 2021 at our institution. In addition\, whole genome sequencing (WGS) was used to characterize respiratory viruses\, particularly SARS-CoV-2\, as i t was the dominant circulating respiratory virus. It was important to asse ss the mutations and evolution of the virus circulating in geographical lo cations where our service members were stationed. In this study we charact erized positive nasopharyngeal specimens submitted to the Tripler Army Med ical Center (TAMC) on Oahu\, Hawaii. Sequencing was conducted using the Il lumina Next-Generation Sequencing and viral genomes were analyzed using Ge neious Prime and CLC workbench. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:360@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221101T090000 DTEND;TZID=Pacific/Honolulu:20221101T100000 DTSTAMP:20221018T184801Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defenseinvestigating-feral-pigs-as-animal-reservoirs-for-nontubercu lous-mycobacteria-in-hawaii-haley-hendrick SUMMARY:Tropical Medicine MS Thesis Defense:"Investigating Feral Pigs As An imal Reservoirs for Nontuberculous Mycobacteria In Hawai’i"\, Haley Hend rick DESCRIPTION:Zoom Meeting ID: 936 3428 6004\nContact jogata22@hawaii.edu for passcode.\n\nHaley Hendrick\nM.S. Candidate\nDepartment of Tropical Medic ine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medic ine\nUniversity of Hawaii at Manoa\n\n\nNontuberculous mycobacteria (NTM) are environmentally-acquired opportunistic pathogens that cause recalcitra nt pulmonary disease in susceptible individuals. The prevalence of NTM pul monary disease is increasing globally\, and the highest rates within the U S are observed in Hawai'i. Mycobacterium porcinum (Latin\, “porcus\,” pig) is the fourth most frequently isolated NTM species from the Hawai’i environment\, and causes lymphadenitis in pigs and wound and pulmonary in fections in humans. Because Hawai’i is home to large populations of inva sive feral pigs\, we hypothesized pigs are animal reservoirs for NTM. This hypothesis was tested with the following aims: 1) Determine the NTM speci es diversity among Hawai’i feral pigs\, and 2) Measure the growth rate o f feral pig\, environmental\, and respiratory NTM\, including environmenta l and respiratory M. porcinum isolates\, and compare survival of these iso lates in human macrophages. In 2021\, we collected a matched set of nasal and fecal samples from 50 deceased O'ahu feral pigs. Samples were microbio logically cultured and NTM were identified using partial gene sequencing. A total of 20 NTM species were identified\, including Mycobacterium absces sus. Five pig-derived NTM isolates and six M. porcinum isolates were selec ted for further characterization including tabulating their colony morphol ogy\, capacity to form biofilms\, and their ability to survive in human TH P-1 macrophages. We found effective control of pig-derived NTM by THP-1 ma crophages but differential production of host cytokines in response to inf ection. M. porcinum isolates showed significant intraspecies variation wit h respect to growth rate and macrophage survival. This study confirms fera l pigs in Hawai’i harbor pathogenic NTM species and may contribute to th e prevalence of NTM in Hawai’i. END:VEVENT BEGIN:VEVENT UID:361@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221026T120000 DTEND;TZID=Pacific/Honolulu:20221026T130000 DTSTAMP:20221021T011751Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarhumor al-immune-responses-to-sars-cov-2-vaccines-in-altered-metabolic-states-oli via-smith-phd-student SUMMARY:TRMD 690 Seminar:"Humoral Immune Responses to SARS-CoV-2 Vaccines i n Altered Metabolic States"\, Olivia Smith\, PhD Student DESCRIPTION:In Person and By Zoom\nZoom ID: 979 6297 5142\nContact jogata22 @hawaii.edu for passcode\n\nOlivia Smith\, M.P.H.\nPh.D. Student\nDepartme nt of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. B urns School of Medicine\nUniversity of Hawaii at Manoa\n\n\n\nCOVID-19 dis ease\, caused by SARS-CoV-2\, led to a global pandemic beginning in Decemb er 2019. The pandemic has led to medical deficits in individual health and problems at the societal and community levels\, including and an increase in health disparities\, especially in those with comorbidities. Comorbidi ties\, including Type 2 diabetes mellitus (T2DM)\, have led to higher rate s of hospitalization\, more severe COVID-19 disease\, and increased mortal ity. Despite this risk\, only a few studies have compared vaccine response s between T2DM and healthy individuals. Due to the increase in the severit y of the disease and mortality rates of those with T2DM\, determining an o ptimal prevention method for COVID-19 disease is a priority. This research proposal identifies three sources of key research aims deliberately devel oped for the evaluation of humoral immunogenicity elicited by SARS-CoV-2 v accines and natural COVID-19 infection. Using an optimized high-throughput multiplex-immunoassay (MIA) and a SARS-CoV-2 Spike glycoprotein (S-GP) su bunit panel in both mouse models of obesity and diabetes and within transl ational research\, the evaluation of humoral immune responses to SARS-CoV- 2 vaccine platforms in altered metabolic states could provide updated vacc ine-related policy change in those with metabolic disorders like obesity o r diabetes. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:359@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221019T120000 DTEND;TZID=Pacific/Honolulu:20221019T130000 DTSTAMP:20221018T181945Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-reco mbinant-vaccine-production-developing-high-yield-platforms-to-express-and- purify-antigens-and-identify-novel-antibodies-targeting-emerging-infectiou s-diseases-ludwig-mayerl SUMMARY:TRMD 690 Seminar: "Recombinant vaccine production: Developing high- yield platforms to express and purify antigens and identify novel antibodi es targeting emerging infectious diseases"\, Ludwig Mayerlen\, PhD Student DESCRIPTION:In-person &\; by Zoom\nZoom ID: 979 6297 5142\nContact jogat a22@hawaii.edu for passcode\n\n\n\n\nLudwig Mayerlen\nPh.D. Student\nDepar tment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A . Burns School of Medicine\nUniversity of Hawaii at Manoa\n\n\n\nEffective expression of recombinant proteins is important in both vaccine developme nt and monoclonal antibody production. To achieve this aim\, we created a new and versatile expression vector that enables high-yield antigen produc tion and is currently used for our efforts to produce recombinant protein vaccines against SARS-CoV-2 and Marburg virus. I will provide updates on o ur efforts to develop a new insect cell line for reproducible and highly e fficient production of recombinant proteins in insect cells utilizing diff erent recombinases. In the second part of this talk\, I will present resul ts of our newly implemented and optimized ExpiCHO system for in-house prod uction of recombinant antibodies. Further\, I will give an outlook on nano body discovery via yeast-nanobody libraries and how this addition of anoth er cutting-edge tool to our current vaccine platform can help us respond m ore rapidly to emerging infectious diseases.\n\n\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:357@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221014T150000 DTEND;TZID=Pacific/Honolulu:20221014T170000 DTSTAMP:20221011T021817Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=asm-hawaii-coffee-hou r-murder-and-microbes SUMMARY:ASM HAWAI‘I COFFEE HOUR: Murder and Microbes DESCRIPTION:Everyone is Invited!\n\nASM HAWAI‘I COFFEE HOUR:\nMURDER & \; MICROBES\nLecture by Dr. David O. Carter\nFree Coffee and Pizza\nPlay G ames and Win Prizes\nBoard Games\nAir Hockey\nPetri Dish Art\nWii CATEGORIES:Coffee Hour LOCATION:JABSOM Medical Education Bldg. Rm. 202\, 651 Ilalo St.\, Honolulu\ , HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educa tion Bldg. Rm. 202:geo:0,0 END:VEVENT BEGIN:VEVENT UID:356@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221012T120000 DTEND;TZID=Pacific/Honolulu:20221012T130000 DTSTAMP:20221010T024257Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690seroprevalenc e-as-marker-of-epidemic-risk-for-lassa-virus-in-liberia-varney-kamara-phd- student SUMMARY:TRMD 690:"Seroprevalence as marker of epidemic risk for Lassa virus in Liberia"\, Varney Kamara\, PhD Student DESCRIPTION:In Person and by Zoom\nZoom Meeting ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcode\n\nVarney M Kamara\nPh.D. Student\nDepart ment of Tropical Medicine\, Medical Microbiology and Pharmacology\, John A . Burns School of Medicine\n\n\nEnzyme Linked Immunosorbent Assays (ELISA) or Immunoblotting assays using whole viral lysates or recombinant protein s have limitations for epidemiological surveillance or diagnosis\, as they are time consuming\, resource intensive and show high false-positive dete ction rates. Serum samples were collected from Ebola virus disease (EVD) a nd Lassa virus (LASV) survivors\, close contacts\, individuals with unknow n status\, semi-stray dogs\, and peri-urban rats to detect antibodies reac tive to a pool of antigens. The results show correlation and cross-reactiv ity among the antigens. Overall\, our results show that the assay is speci fic\, sensitive\, and cost-effective and maybe more useful than a commerci al ELISA that is currently used in Liberia for sero-surveillance and diagn osis of LASV reactivity.\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:355@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20221005T120000 DTEND;TZID=Pacific/Honolulu:20221005T130000 DTSTAMP:20221005T043551Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarimpac t-of-metformin-on-cd4-t-cell-negative-checkpoint-receptors-in-individuals- with-chronic-hiv-thomas-ken-awamura-phd-student SUMMARY:TRMD 690 Seminar:"Impact of metformin on CD4 T cell negative checkp oint receptors in individuals with chronic HIV"\, Thomas Ken Awamura\, PhD student DESCRIPTION:In Person or Zoom\nZoom Meeting ID: 979 6297 5142\nContact cori t@hawaii.edu for passcode\n\n\n\n\nThomas Ken Awamura\, M.S.\nPh.D. Studen t\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology John A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\nMet formin\, primarily used as a first-line therapy for type 2 diabetes\, has also been shown to have a wide range of cardiovascular\, neurocognitive\, and anti-neoplastic benefits. A previous study conducted by the Hawaii Cen ter for AIDS (HCFA) found that participants with chronic HIV taking metfor min over 24 weeks\, led to significant reduction in the expression of nega tive checkpoint receptors (NCR) on CD4 T cells compared to control patient s. A separate study determined that those who had higher levels of activat ed and senescent CD4 T cells as determined by the increased expression of certain NCR\, saw worse neurological impairment\, working memory\, and inc reased peripheral fat over the course of 2 years. The primary objective of this study is to confirm the findings of these previous studies\, while e xpanding the number of participants and considerably increasing the durati on of metformin administration to 72 weeks. Secondarily\, we hope to asses s potential health benefits of decreased levels of activated and senescent CD4 T cells in chronic HIV patients by assessing various parameters inclu ding body composition\, neurocognitive performance\, and measurements of c arotid intima-media thickness (cIMT).\n\n\n\n\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:354@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220928T120000 DTEND;TZID=Pacific/Honolulu:20220928T130000 DTSTAMP:20220923T212700Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarhuman -monkeypox-current-knowledge-and-public-health-implications-rodson-zorilla -ms-student SUMMARY:TRMD 690 Seminar:"Human Monkeypox: Current knowledge and public hea lth implications"\, Rodson Zorilla\, MS Student DESCRIPTION:In Person and by Zoom\nZoom Meeting ID: 979 6297 5142\nEmail jo gata22@hawaii.edu for passcode\nRodson Zorilla\, M.D.\nM.S. Student\nDepar tment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A . Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\nHuman mo nkeypox is a viral zoonotic disease caused by orthopoxvirus that results i n a smallpox-like disease in humans. WHO declared the monkeypox outbreak a s a Public Health Emergency of International Concern. It is evident that t he clinicoepidemiology of the disease is evolving which may pose an obstac le in eliminating the disease. Moreover\, potential evolution of the monke ypox virus could result in increased transmissibility\, less susceptibilit y to innate and adaptive immunity in hosts\, and enhanced virulence. It is therefore necessary to increase research efforts to close the gap of scie ntific knowledge and to optimize the surveillance and preparedness in comb ating monkeypox disease to avoid another pandemic. In this seminar\, I wil l discuss the virological features\, clinicoepidemiological characteristic s of the monkeypox virus\, vaccines and therapeutics for monkeypox virus i nfection\, and its future implication in regards to basic science research and public health. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:353@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220921T120000 DTEND;TZID=Pacific/Honolulu:20220921T130000 DTSTAMP:20220920T071721Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminardevel opment-of-a-multiplex-microsphere-immunoassay-using-dried-filter-paper-blo od-spots-for-testing-sars-cov-2-igg-levels-in-infected-and-or-vaccinated-i ndividuals-maansi-murty SUMMARY:TRMD 690 Seminar:"Development of a Multiplex Microsphere Immunoassa y Using Dried Filter Paper Blood Spots for Testing SARS-CoV-2 IgG Levels i n Infected and/or Vaccinated Individuals"\, Maansi Murty\, MS Student DESCRIPTION:In Person and by Zoom\nJABSOM Medical Education Bldg.\, Access Grid Room 202\nZoom ID: 979 6297 5142\nEmail  jogata22@hawaii.edu for pas scode\nMaansi Murty\nM.S. Student\nDepartment of Tropical Medicine\, Medic al Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniver sity of Hawaii at Manoa\n\n\n\n\nThe traditional blood sample collection u sed in antibody-based assays is through venipuncture (VP). A less invasive technique\, easily conducted in community field settings with limited per sonnel and supplies and stored for years at most temperatures\, is a dried blood spot (DBS). Following informed consent\, matching DBS and VP sample s (n=180) were collected from individuals who recovered from a SARS-CoV-2 natural infection and/or had received a COVID-19 vaccination between April 2021 and May 2022 in Hawai’i. Anti-SARS-CoV-2 spike IgG antibodies were evaluated by a multiplex microsphere immunoassay (MIA). Data indicates th e DBS assay was highly sensitive and specific\, with a strong correlation between matched blood samples. Individuals naturally infected with SARS Co V-2 and vaccinated showed higher levels of IgG antibodies compared to thos e who only received two doses of COVID-19 vaccination. Levels of binding a ntibodies decreased over six months after dose two of vaccination. We repo rt development of a low-cost\, non-invasive technology for measuring SARS- CoV-2 IgG antibody levels using a DBS assay\, which strongly correlates wi th matched VP samples.\n\n\n\n\n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 202\, 651 Ilalo Street\, Honol ulu\, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo Street\, Honolulu \, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Ed ucation Bldg.\, Rm 202:geo:0,0 END:VEVENT BEGIN:VEVENT UID:352@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220914T120000 DTEND;TZID=Pacific/Honolulu:20220914T130000 DTSTAMP:20220912T204638Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarin-vi tro-and-in-vivo-investigation-of-sars-cov-2-infection-in-the-testis-stefan os-giannakopoulos-phd-student SUMMARY:TRMD 690 Seminar:"In-vitro and in-vivo investigation of SARS-CoV-2 infection in the testis"\, Stefanos Giannakopoulos\, PhD Student DESCRIPTION:In Person and By Zoom\nLocation: JABSOM Medical Education Bldg. Rm. 202\nZoom Meeting ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcode.\nStefanos Giannakopoulos\nPh.D. Student\nDepartment of Cell and Molecular Biology\, John A. Burns School of Medicine\,\nUniversity of Hawa ii at Manoa\, Honolulu\, Hawaii\, USA\n\n\n\nThe hallmark of severe COVID- 19 involves systemic cytokine storm and multi-organ failure including test icular injury and germ cell depletion. Cell targets of the virus and mecha nisms of testicular injury are not fully understood. Injury can be because of direct virus infection or cytokine storm-associated pathology. We char acterized SARS-CoV-2 infectivity of different testicular cells and downstr eam effects. Data shows that SARS-CoV-2 does not establish infection in an y testicular cell types\, and viral proteins and inflammatory cytokines dr ive cell death. K18h-ACE2 mouse model also revealed testicular injury in t he absence of virus replication. Collectively\, data strongly indicates th at it is the infection-derived inflammatory response that causes cell deat h.  These data provide novel insights into the mechanism of testicular in jury and could explain the clinical manifestation of testicular symptoms a ssociated with severe COVID-19. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm. 202\, 651 Ilalo St.\, Honolulu\ , HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educa tion Bldg. Rm. 202:geo:0,0 END:VEVENT BEGIN:VEVENT UID:351@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220907T120000 DTEND;TZID=Pacific/Honolulu:20220907T130000 DTSTAMP:20220907T031355Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-tropical-med icine-career-development-seminar-a-winding-road SUMMARY:TRMD 690 Tropical Medicine Career Development Seminar - "A Winding Road"\, Robert McLinden\, PhD DESCRIPTION:Zoom ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcod e.\nRobert McLinden\, Ph.D.\nProgram Manager/Medical Division\nOdyssey Sys tems Consulting\nFairfax\, Virginia\n\n\n\nIn this seminar\, Dr. McLinden will take you through the various stages of his career in HIV-1 basic rese arch\, vaccine development and preparations for clinical trials of an HIV- 1 vaccine in the Military HIV Research Program.  He will then explain how he leveraged this experience to pursue other career opportunities in the private sector. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:350@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220902T100000 DTEND;TZID=Pacific/Honolulu:20220902T110000 DTSTAMP:20220816T213233Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=special-one-health-se minar-attaining-lasting-optimal-health-for-all-how-the-one-health-approach -is-a-tool-for-achieving-your-vision-bonnie-buntain-bs-ms-dvm-university-o f-ariz SUMMARY:Special One Health Seminar:” Attaining Lasting Optimal Health for All: How the One Health Approach is a Tool For Achieving Your Vision”\, Bonnie Buntain\, BS\, MS\, DVM\; University of Arizona DESCRIPTION:In-Person and By Zoom\nZoom Meeting ID: 979 6297 5142\nContact jogata22@hawaii.edu for passcode\nBonnie J. Buntain\, BS\, MS\, DVM\nDiplo mate Emerita American Board of Veterinary Practitioners\nDiplomate America n College of Veterinary Preventive Medicine\nProfessor Emerita\, Public He alth and Food Safety\, Faculty of Veterinary Medicine and Faculty of Medic ine\, University of Calgary\, Canada\nAcademic Programs Officer III\, Coll ege of Veterinary Medicine\, University of Arizona\n\n\n\nThis seminar is a call to action to apply the One Health transdisciplinary approach to res earch\, educational and service programs. The One Health approach will be described historically as well as using current paradigms. The root cause s of the emergence of diseases will exemplify the urgent need for academia and other organizations to integrate the One Health approach across disci plines and to engage community-based and indigenous knowledge in each step of the process.  The added value of implementing the One Health concept ual framework into academia is described as well as the barriers and enabl ers to implementation.  The importance of the One Health approach to res earch will be illustrated by case examples.  To achieve the vision of A.L .O.H.A.\, the University of Hawaii and JABSOM have an incredible opportuni ty to build on what is already in place\, and purposefully use the One Hea lth approach to build interdisciplinary and transdisciplinary capacity to solve the unprecedented challenges that global health faces now and in an all-too-near future.\nSponsored by The Hans and Ilza Veith Annual Lectures hip in the History of Medicine at JABSOM  in Memory of Charles Judd\, Jr. CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:349@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220803T120000 DTEND;TZID=Pacific/Honolulu:20220803T130000 DTSTAMP:20220721T210844Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-bradley-makdevelopment-of-microfluidics-for-use-in-a-novel- approach-to-characterize-latently-hiv-infected-cells SUMMARY:Tropical Medicine MS Thesis Defense - Bradley Mak:"Development of M icrofluidics for Use in a Novel Approach to Characterize Latently HIV-infe cted Cells" DESCRIPTION:In Person and by Zoom\nZoom ID: 979 6297 5142\nContact corit@ha waii.edu for passcode\n \;\nBradley Mak \nM.S. Candidate \nDepartmen t of Tropical Medicine\, Medical Microbiology and Pharmacology \nJohn A. Burns School of Medicine \nUniversity of Hawaii at Manoa\n\n\nAntiretrovi ral therapy (ART) has been transformative in helping people living with HI V (PLWH) in the last 30 years. Despite the many advances in ART\, it canno t eradicate HIV due to its inability to target the HIV latent reservoir\, consisting of infected CD4+ T-cells harboring transcriptionally silent\, H IV proviral DNA that require activation by external stimuli. Therapeutic a pproaches have been considered for eradicating latent HIV such as “shock and kill” and “block and lock” but are still in development and hav e shown poor results in clinical trials thus far. Such pursuits would bene fit from a deeper understanding of HIV latency. Therefore\, we introduce H IV-Seek\, a novel approach to characterizing latently HIV infected cells i n their pre-activated state. HIV-Seek aims to combine microfluidics\, sing le cell RNA-sequencing\, and molecular biology to identify biomarkers for immunological or pharmacological control of the viral reservoir. The focus of this thesis is to establish the development of microfluidics for both its fabrication and function in HIV-Seek alongside the integration of micr ofluidics and molecular biology. CATEGORIES:Seminar LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:348@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220729T150000 DTEND;TZID=Pacific/Honolulu:20220729T160000 DTSTAMP:20220721T205827Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cell-molecular-biolog y-phd-defense-brien-haunmethods-to-characterize-anti-viral-immune-response s-reveal-potent-adjuvants-novel-antibody-genes-and-serological-techniques- to-address-viral-outbre SUMMARY:Cell & Molecular Biology PhD Defense - Brien Haun:"Methods To Chara cterize Anti-Viral Immune Responses Reveal Potent Adjuvants\, Novel Antibo dy Genes\, And Serological Techniques To Address Viral Outbreaks" DESCRIPTION:Zoom Meeting ID: 910 8680 7361\nContact beckyn@hawaii.edu for p asscode\n\nBrien Haun\nCell &\; Molecular Biology PhD Candidate\nJohn A Burns School of Medicine\nUniversity of Hawaii at Manoa\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:346@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220725T130000 DTEND;TZID=Pacific/Honolulu:20220725T140000 DTSTAMP:20220718T224212Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-seminar-for-thomas-awamurainhibition-of-type-i-ifn-pathway-by-west- nile-virus-ns4a-and-ns4b-proteins SUMMARY:Tropical Medicine MS Thesis Defense Seminar for Thomas Awamura:"Inh ibition of Type I IFN Pathway by West Nile Virus NS4A and NS4B Proteins" DESCRIPTION:In-person Location: JABSOM\, MEB Auditorium (Room315)\nZoom Mee ting ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode\n\nThomas K en Awamura\nMS Candidate\nDepartment of Tropical Medicine\, Medical Microb iology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\nAs the public health threat of flaviviruses continu es to become increasingly prevalent in both tropical and subtropical areas of the world\, it has become of increasing interest to study the interact ions between flaviviral proteins and those of our innate immune pathways. One such flavivirus\, West Nile Virus (WNV) currently has no vaccine or sp ecific antiviral treatment\, despite recent advances in research for simil arly related viruses such as Dengue. The focus of this project is to deter mine the interaction of WNV NS4A and NS4B proteins with host IKKe and TBK1 of the type 1 IFN pathway and indicate these two proteins as potential an tiviral drug target candidates for future antiviral research. Our findings suggest that WNV NS4A and NS4B proteins interact with IKKe and TBK1 and i nhibit their activities as potent inducers of type I IFN production\, enha ncing the virus' immune evasion capabilities. These findings may imporve i nterest in the targeting of NS4A and NS4B in WNV as potential targets for future antiviral drug development. LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:347@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220715T140000 DTEND;TZID=Pacific/Honolulu:20220715T150000 DTSTAMP:20220713T024255Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-dept-of-tropica l-medicine-marc-mhrt-seminar-career-path-fireside-chat-with-university-of- hawaii-and-marc-alumni-dr-henry-cheng SUMMARY:COBRE/DEPT. OF TROPICAL MEDICINE/MARC/MHRT SEMINAR: "Career Path Fi reside Chat with University of Hawaii and MARC Alumni: Dr. Henry Cheng" DESCRIPTION:In Person &\; Zoom Options\nZoom Meeting ID: 994 7138 3944\ nContact cmlum@hawaii.edu for passcode\nCall in: (669) 900-6833\n \;\n Henry Cheng\, M.A.\, M.S.\, Ph.D.\nAssociate Director of Health Economics &\; Outcomes Research\nUltragenyx Pharmaceutical Inc.\n\n\n\nIn this ca reer development-focused fireside chat\, Dr. Cheng will chat about his car eer journey and answer questions such as:\n\n How do I position myself to be a grad student or postdoc at a top university?\n If I got in\, would I be smart enough to compete?\n What are some career options for graduate s of the biosciences-related majors in industry?\n CATEGORIES:Informational Meeting LOCATION:JABSOM Medical Education Bldg. Rm. 202\, 651 Ilalo St.\, Honolulu\ , HI\, United States GEO:21.2964369;-157.8637169 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education Bld g. Rm. 202:geo:21.2964369,-157.8637169 END:VEVENT BEGIN:VEVENT UID:345@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220630T110000 DTEND;TZID=Pacific/Honolulu:20220630T120000 DTSTAMP:20220621T185623Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-for-michael-faundoelucidating-the-antimicrobial-and-antivir al-activities-of-a-novel-class-of-organobismuth-compounds SUMMARY:Tropical Medicine MS Thesis Defense for Michael Faundo:"Elucidating the antimicrobial and antiviral activities of a novel class of organobism uth compounds" DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nIn-person Location: JABSOM MEB Auditorium\nContact cmlum@hawaii.edu for Zoom passcode\n\nMichael Faundo\n MS Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and P harmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Ma noa\n\n\n\nDevelopment of highly effective\, broad-spectrum antimicrobial and antiviral agents is a major objective shared by the fields of microbio logy\,virology and pharmaceutics. Antibiotics have been instrumental I red ucing illness and death from microbial infections since the 1940s. However \, this widespread use has also led to the advent of multidrug resistance among pathogenic bacteria\, with millions dying to infection to such organ isms annually. The crisis of antimicrobial resistance has been ascribed to the misuse of these agents and unavailability of newer drugs attributable to demanding regulatory requirements. In contrast\, while there are broa d-spectrum agents available for antimicrobial uses\, the conventional app roach for development of antivirals is a ‘one-bug-one-drug’ paradigm. With the growing challenges of emerging and re-emerging viral\npathogens\, the present modality is insufficient to address these issues\, with few d rugs  currently available to a prompt control of epidemic viral diseases. While metal compounds have found use as antimicrobial agents\, but their antiviral activities have rarely been explored. The focus of this research aims to characterize the potential antimicrobial and antiviral activitie s of a novel class of organobismuth compounds.\n\n\n\n \;\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:344@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220519T140000 DTEND;TZID=Pacific/Honolulu:20220519T150000 DTSTAMP:20220518T005845Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminaruniformed-services-university-infectious-disease-clinical-resear ch-program-idcrp-impact-on-military-clinical-practice-and-policy-david-tri bble-md-drph-unifor SUMMARY:COBRE/Tropical Medicine Seminar:"Uniformed Services University Infe ctious Disease Clinical Research Program (IDCRP): Impact on Military Clini cal Practice and Policy"\, David Tribble\, MD\, DrPH\, Uniformed Services University DESCRIPTION:JABSOM Medical Education Bldg.\, Rm. 202 (Access Grid Room)\nZo om Meeting ID: 930 8868 6570\n \;\nContact cmlum@hawaii.edu for passc ode\n \;\nDavid Tribble\, M.D.\, Dr.P.H.\nScience Director\nInfectious Disease Clinical Research Program\nProfessor\nDepartment of Preventive Me dicine &\; Biostatistics and Department of Medicine\nUniformed Services University (USU)\nBethesda\, Maryland\n\n\nDr. Tribble completed his medi cal training at the University of Arkansas for Medical Sciences followed b y Internal Medicine residency at the Naval Hospital Portsmouth\, Infectiou s Diseases fellowship at the National Naval Medical Center (NNMC)\, and a Doctorate in Public Health at the Uniformed Services University of the Hea lth Sciences (USU). After assignments at the Naval Medical Research Unit N o. 3 in Cairo\, Egypt\, NNMC Infectious Diseases Division\, and the Enteri c Diseases Department\, Naval Medical Research Center\, Dr. Tribble joined the faculty at USU to establish the Infectious Disease Clinical Research Program (IDCRP)\, a Department of Defense and National Institute of Allerg y and Infectious Disease (NIAID)/National Institutes of Health (NIH) colla borative research program. As IDCRP Science Director\, Dr. Tribble provide s senior leadership for strategic planning and clinical research. Dr. Trib ble’s areas of research focus include trauma-related infectious complica tions\, SSTI epidemiology and S. aureus infection prevention strategies\, deployment/travel-associated infection epidemiology and clinical managemen t. Dr. Tribble has also had longstanding research efforts in the field of bacterial diarrheal disease vaccine development including development and investigation of experimental infection models in volunteers\, with partic ular emphasis on Campylobacter jejuni. CATEGORIES:Seminar LOCATION:JABSOM MEB 202\, 651 Ilalo St.\, Honolulu\, HI\, 96813\, United St ates X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM MEB 202:geo:0 ,0 END:VEVENT BEGIN:VEVENT UID:342@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220504T171500 DTEND;TZID=Pacific/Honolulu:20220504T191500 DTSTAMP:20220428T001700Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=minority-health-resea rch-training-program-2022-presentations SUMMARY:Minority Health Research Training Program 2022 Presentations DESCRIPTION:Comorbidities Associated with Hospitalization and Mortality of Native Hawaiians and Pacific Islanders with COVID-19\nChelsea Nicholas\, B .S.\, GCERT\nM.S. Student\nDepartment of Tropical Medicine\, Medical Micro biology and Pharmacology\n\nPacific Islanders in the Era of COVID-19: An O verlooked Community in Need\nPakieli H. Kaufusi\, Ph.D.\nAssistant Profess or\nDepartment of Tropical Medicine\, Medical\n\nMeeting ID: 942 7613 5348 \nContact airamae4@hawaii.edu for passcode CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:343@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220504T120000 DTEND;TZID=Pacific/Honolulu:20220504T130000 DTSTAMP:20220503T075918Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarenhan ced-whole-genome-sequencing-workflow-rennsilve-salomon-ms-student-sars-cov -2-neutralizing-antibody-predictive-value-lauren-ching-phd-student SUMMARY:TRMD 690 Seminar:"Enhanced Whole Genome Sequencing Workflow"\, Renn silve Salomon\, MS Student\; "SARS-CoV-2 Neutralizing Antibody Predictive Value"\, Lauren Ching\, PhD Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode\n \n\n\n\nRennsilve Salomon\nM.S. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\,  University of Hawaii at Manoa\n"Enhanced Whole Genome Sequencing Workflo w to Augment the Number of Sequences Submitted to the GenBank"\nWhole geno me sequencing (WGS) is essential for monitoring mutations and detecting th e emergence of SARS-CoV-2 variants. WGS is expensive and time consuming. O ur goal was to identify high-quality RNA extracted from nasal swabs from S ARS-CoV-2 infected patients for WGS\, followed by submission of ~30-kb cle an SARS-CoV-2 sequence to the GenBank. In this presentation\, I will descr ibe how we utilized DNA concentration and gel ratios in identifying a bett er indicator for WGS. Instituting a DNA concentration cut-off of 1.096 ng/ mL decreased samples processed for sequencing by 7% and increased WGS subm ission by 15% thus conserving reagents and time to submission.\nLauren Chi ng\nPh.D. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n"SARS-CoV-2 Neutralizing Antibody Predictive Value In Individua ls with COVID-19 Vaccination using a Microsphere Immunoassay"\nAntibody ki netics following a SARS-CoV-2 infection and COVID-19 vaccination are essen tial to understanding the natural history of the disease/vaccination and a djusting public health measures. Here we present neutralizing antibody (NA b) and binding antibody kinetics among a local cohort of individuals with and without a history of SARS-CoV-2 natural infection and/ or COVID-19 vac cination. Our data demonstrates\, i) potent COVID-19 vaccine-induced NAb r esponses\, are significantly increased compared to SARS-CoV-2 natural infe ction\; ii) natural infection followed by vaccination has a moderate incre ase in NAb levels when compared to administration of two-dose vaccine seri es (p = 0.033)\; iii) NAb titers at three and six months following the sec ond dose of a COVID-19 vaccine significantly declined\; and iv) NAb titers were significantly increased within two weeks following a booster dose of a COVID-19 vaccine. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:340@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220427T130000 DTEND;TZID=Pacific/Honolulu:20220427T130000 DTSTAMP:20220425T215234Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarone-s tudents-experience-in-a-tropical-medicine-career-all-roads-led-to-the-labo ratory-mallory-wilson-ms-student SUMMARY:TRMD 690 Seminar:"One Student’s Experience In a Tropical Medicine Career…..all Roads Led To the Laboratory"\, Mallory Wilson\, MS Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode\n \nMallory Wilson\, MPHTM\nM.S. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nU niversity of Hawaii at Manoa\n\n\nTropical medicine is a relatively unknow n field with a focus on infectious diseases commonly found in tropical are as\, diseases of poverty\, and neglected tropical diseases (NTDs). The tro pical medicine field incorporates components from clinical\, laboratory\, epidemiological\, and field work. Upon building a training and educational platform in tropical medicine\, Mallory identified that she would benefit from a combination of these components and sought out opportunities in ea ch. These include a local malaria epidemic investigation in Ghana\, surgic al access research in rural Haiti\, and Zika and dengue virus cluster trac king for the World Health Organization (WHO). Following these\, she set ou t to pursue the final check box\, experimental research. Mallory is a new graduate student in the lab of Dr. Saguna Verma. The current research focu s of the Verma lab is to understand SARS-CoV-2 pathogenesis in extrapulmon ary organs including the testes. In the last 8 months\, Mallory has been t rained in different techniques related to SARS-CoV-2 infection in both BSL 2 and BSL3 laboratories. She has participated in characterizing the cytopa thic effects of SARS-CoV-2 antigens on different testicular cells. Mallory ’s upcoming projects will further investigate the effects of different S ARS-CoV-2 proteins on other cell types including microvascular endothelial cells and cardiomyocytes to understand their role in promoting inflammati on independent of virus infection. This seminar will cover Mallory’s exp erience in tropical medicine from a clinical and public health perspective and how her training led her to explore infectious disease research in a laboratory setting in order to cultivate a well-rounded career. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:341@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220427T083000 DTEND;TZID=Pacific/Honolulu:20220427T093000 DTSTAMP:20220426T211742Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-dengue-and-immuno-epidemiology-research-of-schistosomiasis-at-t he-research-institute-for-tropical-medicine-in-philippines-mario-jiz-phd-a va-kristy-sy-rmt-mac SUMMARY:COBRE/Tropical Medicine Seminar:" Dengue and Immuno-Epidemiology Re search of Schistosomiasis at the Research Institute for Tropical Medicine in Philippines\," Mario Jiz\, PhD\; Ava Kristy Sy\, RMT\, Mac\, Research I nstitute for Tropical Medicine\, Philippines DESCRIPTION:Zoom Meeting ID: 985 1235 6494\nContact cmlum@hawaii.edu for pa sscode\n\nMario Jiz\, Ph.D.\nHead\, Immunology Department\nAva Kristy Sy\, R.M.T.\, M.Sc.\nNational Reference Laboratory for Dengue and other Arbovi rus\nVirology Department\nResearch Institute for Tropical Medicine\nManila \, Philippines\n\n\n\nAn introduction of the Research Institute for Tropic al Medicine (RITM) in Philippines will be provided\, followed by discussio n of several ongoing research activities there with focus on Dengue and Sc histosomiasis. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:339@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220420T120000 DTEND;TZID=Pacific/Honolulu:20220420T130000 DTSTAMP:20220420T220453Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-char acterizing-protective-antibody-responses-to-a-recombinant-subunit-ebola-vi rus-vaccine-aquena-ball-phd-student SUMMARY:TRMD 690 Seminar:” Characterizing Protective Antibody Responses T o a Recombinant Subunit Ebola Virus Vaccine”\, Aquena Ball\, PhD Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode\n \nAquena Ball\n\nPh.D. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\n\nJohn A. Burns School of Medicine\nUnivers ity of Hawaii at Manoa\n\n\n\n\n\nEbola virus (EBOV) causes lethal hemorrh agic fever with case fatality rates of up to 90%. Outbreaks are sporadic a nd unpredictable and vaccination has been key to controlling disease. Howe ver\, due to limited stocks of approved vaccines and requirement of cold-c hain storage\, there is a need to continue developing new vaccines with mo re appropriate product characteristics. In addition\, although all vaccine candidates use the surface glycoprotein as the main antigen\, the method of protection induced by the EBOV glycoprotein remains unclear. We have de veloped a recombinant subunit vaccine that has an increased safety profile and thermostability\, allowing easier deployment in endemic regions. Our vaccine has shown high efficacy in the gold standard non-human primate mod el\, with 3 doses showing 100% protection. Characterizing these protective antibody responses is ongoing. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:333@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220416T083000 DTEND;TZID=Pacific/Honolulu:20220416T150000 DTSTAMP:20220325T083206Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hi-noca-asm-2022-join t-spring-meeting SUMMARY:HI/NoCa ASM 2022 Joint Spring Meeting DESCRIPTION:The HI-ASM 2022 Spring Meeting is co-hosted by the Hawaii and N orth California Branches of ASM.  This virtual meeting* is  an excellent opportunity for undergraduates\, graduate students\, and post-doctoral re searchers to share their research in oral or poster formats with their pee rs in other microbiology-related fields.\n*All virtual meeting links will be hosted by NoCa-ASM\n\nAgenda (HST)\n\n\n8:30 am “Brucellosis and Chal lenges in Diagnosis”\nGeorge F. Araj\, PhD\nDirector of Clinical Microbi ology\nUniversity of Beirut Medical Center\n9:30 am Break\n9:50 am “Stra tegies to Characterize the Prevalence of Carbapenemase producing Organisms (CPOs) and Candida auris in Hawai’i”\nPriscilla Seabourn\, PhD\nPost- Doctoral Research Associate\nAPHL\, CDC\, Hawai‘i State Laboratories Div ision\n10:50 am Break\n11:00 am -2:30 pm (TBD based on # of presenters) St udent Oral Presentations/Posters*\n*Posters available on our website with a live chat feed for each presenter*\n2:30 pm -3:00 pm (TBD) Hi-ASM Meetin g\nEach speaker and presenter will have their own dedicated Zoom link (pro vided by NoCaASM)\, links will be announced to registrants via email and p rovided on a detailed agenda on our website: http://hi-asm.org\nAbstract D eadline: Monday\, April 4\, 2022\n\nREGISTRATION\nONLINE ABSTRACT SUBMISSI ON\nMEETING FLYER\n\n\n\n\nFor meeting information\, contact Samantha Gab rielle Morgan\, HI-ASM Student Treasurer\, E-mail: sgmorgan@hawaii.edu\n\ nFor questions about abstract submission\, contact Olivia Smith\, oasmith@ hawaii.edu.  More abstract details available at http://hi-asm.org CATEGORIES:Research Symposium END:VEVENT BEGIN:VEVENT UID:337@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220413T120000 DTEND;TZID=Pacific/Honolulu:20220413T130000 DTSTAMP:20220402T022751Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-thes is-defensedevelopment-of-the-molecular-biology-of-hiv-seek-a-novel-approac h-to-characterizing-latently-infected-cd4-t-cells-eduardo-games-ms-candida te SUMMARY:TRMD 690 Seminar & Thesis Defense:"Development of the Molecular Bio logy of HIV-Seek: A Novel Approach to Characterizing Latently Infected CD4 + T Cells"\, Eduardo Gamez\, MS Candidate DESCRIPTION:Zoom and In-Person\, JABSOM Medical Education Building Access G rid Room 202\nZoom Meeting ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode\n\nEduardo Gamez\nM.S. Candidate\nDepartment of Tropical Medicin e\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicin e\, University of Hawaii at Manoa\n\n\n\nAntiretroviral therapy is effecti ve at managing HIV infection and extending the lives of people living with HIV. However\, its inability to target latently infected CD4+ T cells exp oses latency as a significant barrier to a functional cure. Current techni ques to characterize these cells are limited due to the scarcity of latenc y and the stipulation to activate latently infected cells. Here we introdu ce a novel approach called HIV-Seek that aims to characterize the pre-acti vated transcriptome of latently infected CD4+ T cells. This characterizati on will reveal more information on an infected cell in its latent state an d may enable the identification of a biomarker unique to latently infected cells. In this study\, we establish the bead-based molecular techniques t hat demonstrate the use of oligo-dT-conjugated beads to facilitate reactio ns involved in HIV-Seek. CATEGORIES:Seminar LOCATION:John A Burns School of Medicine\, Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=John A Burns Schoo l of Medicine\, Medical Education Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:335@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220407T120000 DTEND;TZID=Pacific/Honolulu:20220407T130000 DTSTAMP:20220325T195814Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=jabsom-biomedical-sci ences-and-health-disparities-symposium-keynote-immunological-sequelae-of-e merging-virus-infection-during-pregnancy-jae-ung-jung-phd SUMMARY:JABSOM Biomedical Sciences and Health Disparities Symposium Keynot e: ”Immunological Sequelae of Emerging Virus Infection During Pregnancy ”\, Jae Ung Jung\, PhD DESCRIPTION:John A. Burns School of Medicine\nBiomedical Sciences and Healt h Disparities Symposium\n\nKeynote Speaker\n \;\nJae Ung Jung\, PhD\nB etsy B deWindt Professor\nChair of Cancer Biology Department\, Lerner Rese arch Institute\nDirector of Global Center for Pathogen and Human Health Re search\nCleveland Clinic\, Ohio\nImmunological Sequelae of Emerging Virus\ nInfection During Pregnancy\n \;\nHybrid event: Attend in-person or vi a Zoom\n \nIn person event: Medical Education Building Auditorium\, MEB 3 15\, \nJABSOM\, 651 Ilalo Street\, Honolulu\, HI\nZoom: Meeting ID: 882 04 71 1230\nPasscode: jabsom2022\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:334@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220407T080000 DTEND;TZID=Pacific/Honolulu:20220408T170000 DTSTAMP:20220325T083651Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=biomedical-sciences-a nd-health-disparities-symposium SUMMARY:Annual Biomedical Sciences and Health Disparities Symposium DESCRIPTION:The Annual Biomedical Sciences &\; Health Disparities Sympos ium will be a two day event with both live and online sessions.\nApril 7\, 2022\nZoom oral presentations by medical students\, residents\, and medic al fellows\nLive poster presentations by graduate students and post-doctor al fellows\nKeynote Speaker Presentation\n  April 8\, 2022\nLive poster p resentations by undergraduate students\n\n\n\n\nKeynote Speaker: Jae Ung J ung\, PhD\nBetsy B deWindt Professor\nChair of Cancer Biology Department\n Lerner Research Institute\, Cleveland Clinic\, Ohio\nand\nProfessor of Mol ecular Medicine Department\nCleveland Clinic Lerner College of Medicine\n\ n"Immunological sequelae of emerging virus infection during pregnancy"\n\n \nRegistration is required for all participants: REGISTRATION PAGE\n \ ; CATEGORIES:Research Symposium LOCATION:John A Burns School of Medicine\, 651 Ilalo St.\, Honolulu\, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=John A Burns School of Medicine:geo:0,0 END:VEVENT BEGIN:VEVENT UID:338@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220406T120000 DTEND;TZID=Pacific/Honolulu:20220406T130000 DTSTAMP:20220401T083928Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminara-bri ef-literature-review-of-serological-tests-used-in-the-diagnosis-of-neuroan giostrongyliasis-to-evaluate-utility-for-use-in-hawaii-charmaine-kuehne-ms -student SUMMARY:TRMD 690 Seminar:"A Brief Literature Review of Serological Tests Us ed in the Diagnosis of Neuroangiostrongyliasis to Evaluate Utility for use in Hawai`i"\, Charmaine Kuehne\, MS Student DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact cmlum@hawaii.edu for pa sscode\n\nCharmaine Kuehne\nM.S. Student\nDepartment of Tropical Medicine\ , Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\ , University of Hawaii at Manoa\n\n\n\nNeuroangiostrongyliasis (NAS) is ca used by the nematode Angiostrongylus cantonensis\, a potentially fatal neu rologic disease commonly known as rat lungworm disease. In Hawai`i\, patie nts infected with this parasite have experienced a variety of debilitating sequelae\, from chronic headaches and allodynia to coma. Rapid diagnosis is essential to minimizing long-term complications. Currently\, molecular assays are run on cerebrospinal fluid\, which leads to a delay in diagnosi s. Over the past decade\, the use of various parasite proteins has improve d serological methods developed for the rapid diagnosis of NAS.\nA literat ure review was performed to determine the diagnostic utility of these assa ys for use in Hawai‘i. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:336@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220330T120000 DTEND;TZID=Pacific/Honolulu:20220330T130000 DTSTAMP:20220329T204201Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarpatho genic-ntm-in-hawaiian-feral-pigs-haley-hendrick-ms-student SUMMARY:TRMD 690 Seminar:"Pathogenic NTM in Hawaiian Feral Pigs"\, Haley He ndrick\, MS Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode.\ n\nHaley Hendrick\nM.S. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversi ty of Hawaii at Manoa\n\n\n\nNon-tuberculous Mycobacteria (NTM) are ubiqui tous in natural and man-made environments. They are a class of emerging pa thogens in the United States\, with Hawai'i having the highest prevalence of NTM pulmonary disease. A study from the Honda Lab found rapid-growing N TM Mycobacterium porcinum\, an established pathogen of both humans and pig s (Sus scrofa)\, in 11.8% of sampled households and 3.8% of environmental samples. Because the Hawaiian Islands are home to a large population of in vasive feral pigs\, we hypothesize that the Hawaiian feral pig is an undes cribed reservoir for human NTM infections. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:332@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220323T120000 DTEND;TZID=Pacific/Honolulu:20220323T130000 DTSTAMP:20220321T221601Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarrepur posing-screening-of-clinically-approved-drugs-to-attenuate-flavivirus-ns3- ns2b-interaction-bryan-rios-ms-student SUMMARY:TRMD 690 Seminar:"Repurposing screening of clinically approved drug s to attenuate flavivirus NS3/NS2B interaction"\, Bryan Rios\, MS Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode.\ n\nBryan Rios\nM.S. Student\nDepartment of Tropical Medicine\, Medical Mic robiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity o f Hawaii at Manoa\n\n\n\nFlaviviruses\, such as the West Nile virus\, deng ue virus\, and Zika virus\, pose an enormous threat to global public healt h. The increasing emergence and re-emergence of flaviviral infections comb ined with the lack of clinically approved therapeutics necessitate a rapid strategy for drug development. Drug repurposing screening of clinically a pproved drugs offers speed and cost-saving that may be readily advanced to clinical trials. We have shown that flavivirus NS2B plays dual roles as a co-factor for the viral NS3 protease activity and the inherent ability to recruit NS3 from the cytoplasm to the viral RNA synthesis and assembly si te\, making these proteins an excellent target for drug screening. Using a high-throughput target-based protein complementation assay\, twenty-four FDA-approved drugs will be screened on cells co-expressing NS3\, and NS2B fused to Large BiT and Small BiT of the bright NanoLuc® luciferase\, resp ectively. Potential inhibitors that disrupt the NS3/NS2B binding will decr ease the luciferase activity. A viral titer reduction assay will confirm t he selected compounds. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:331@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220309T120000 DTEND;TZID=Pacific/Honolulu:20220309T130000 DTSTAMP:20220308T195316Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminareluci dating-the-antimicrobial-and-antiviral-activities-of-a-novel-class-of-orga nobismuth-compounds-michael-faundo-ms-student SUMMARY:TRMD 690 Seminar:"Elucidating the antimicrobial and antiviral activ ities of a novel class of organobismuth compounds"\, Michael Faundo\, MS S tudent DESCRIPTION:Zoom ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcod e\n\nMichael Faundo\nM.S. Student\nDepartment of Tropical Medicine\, Medic al Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniver sity of Hawaii at Manoa\n\n\n\nDevelopment of highly effective\, broad-spe ctrum antimicrobial and antiviral agents is a major objective shared by th e fields of microbiology\, virology and pharmaceutics. Antibiotics have be en instrumental in reducing illness and death from microbial infections si nce the 1940s. However\, this widespread use has also led to the advent of multidrug resistance among pathogenic bacteria\, with millions dying to i nfection to such organisms annually. The crisis of antimicrobial resistanc e has been ascribed to the misuse of these agents and unavailability of ne wer drugs attributable to demanding regulatory requirements. In contrast\, while there are broad-spectrum agents available for antimicrobial uses\, the conventional approach for development of antivirals is a ‘one-bug-on e-drug’ paradigm. With the growing challenges of emerging and re-emergin g viral pathogens\, the present modality is insufficient to address these issues\, with few drugs currently available to a prompt control of epidemi c viral diseases. While metal compounds have found use as antimicrobial ag ents\, but their antiviral activities have rarely been explored. The focus of this research aims to characterize the potential antimicrobial and ant iviral activities of a novel class of organobismuth compounds.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:330@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220302T120000 DTEND;TZID=Pacific/Honolulu:20220302T130000 DTSTAMP:20220302T014853Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarcomor bidities-associated-with-hospitalization-and-mortality-in-native-hawaiians -and-pacific-islanders-with-covid-19-chelsea-nicholas-ms-student SUMMARY:TRMD 690 Seminar:"Comorbidities Associated with Hospitalization and Mortality in Native Hawaiians and Pacific Islanders with COVID-19"\, Chel sea Nicholas\, MS Student DESCRIPTION:\nZoom ID: 979 6297 5142\nContact kspedden@hawaii.edu for passc ode.\n\nChelsea Nicholas\nM.S. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nU niversity of Hawaii at Manoa\n\n\n\nRace and ethnicity can serve as a mark er for underlying systemic and structural inequities that steer health dis parities. Associations of risk factors with COVID-19 outcomes have been sh own to differ by racial and ethnic groups. Hence\, disaggregated race data can unveil health disparities across subpopulations. In Hawaii\, Native H awaiians and Pacific Islanders (NHPI) have been the most overrepresented i n COVID-19 cases\, hospitalizations\, and deaths since March 2020. The maj ority of NHPI present with several pre-existing health conditions\, known to significantly increase risk of severe COVID-19 illness and death. Yet\, risk-adjusted differences in COVID-19 outcomes among patients of differin g ethnicity and race categories are not well characterized. To achieve thi s\, we will investigate the association of race and ethnicity with comorbi dities and mortality among NHPI patients with COVID-19 in Hawaii’s large st healthcare system from March 2020 to December 2021. These findings will enhance the current efforts to tailor COVID-19 health information\, treat ment\, and prevention strategies directed toward the underserved populatio ns. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:329@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220223T120000 DTEND;TZID=Pacific/Honolulu:20220223T130000 DTSTAMP:20220222T203725Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarinves tigating-the-use-of-ultra-small-iron-oxide-nanoparticles-as-a-subunit-vacc ine-delivery-platform-with-adjuvant-like-properties-aneesa-golshan-phd-stu dent SUMMARY:TRMD 690 Seminar:"Investigating the Use of Ultra-Small Iron Oxide N anoparticles as A Subunit Vaccine Delivery Platform With Adjuvant-Like Pro perties"\, Aneesa Golshan\, PhD Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcod e.\n\nAneesa Golshan\n\nPh.D. Student\nDepartment of Tropical Medicine\, M edical Microbiology and Pharmacology\n\nJohn A. Burns School of Medicine\n University of Hawaii at Manoa\n\n\nSubunit vaccines have reduced reactogen icity and are safer for immunosuppressed populations such as the elderly\, pregnant women\, or the immunocompromised\, however\, they often lack in immunogenicity and long-term effectiveness. In order to improve upon these vital qualities\, adjuvants are frequently added to subunit vaccine formu lations. However\, few FDA-approved adjuvants exist and their mechanisms o f action are often poorly understood or limited to specific study conditio ns. Inorganic nanoparticle delivery systems with built-in adjuvant propert ies have the potential to address this issue and increase subunit vaccine immunogenicity without the need for additional adjuvants to be added to va ccine formulations. Our research indicates that the functionalized iron-ox ide nanoparticles possess adjuvant-like properties and are internalized by bone marrow-derived dendritic cells. The purpose of this research is to e lucidate the mechanism of action of functionalized iron oxide nanoparticle s of various sizes on the innate immune system\, with a focus on dendritic cells. Overall\, we aim to identify an optimal size of iron oxide nanopar ticles for use in subunit vaccines to improve the immunogenicity of subuni t antigens without added adjuvant. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:328@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220216T120000 DTEND;TZID=Pacific/Honolulu:20220216T130000 DTSTAMP:20220210T221218Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-sars -cov-2-vaccine-induced-antibody-avidity-troy-odo-ms-student SUMMARY:TRMD 690 Seminar: "SARS-CoV-2 Vaccine Induced Antibody Avidity"\, T roy Odo\, MS Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcod e.\n\nTroy Odo\nM.S. Student\nDepartment of Tropical Medicine\, Medical Mi crobiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa\n\n\n\nOver the past two years\, SARS-CoV-2 has had a d evastating impact across the world. To combat the emergence of this virus\ , two effective mRNA vaccines were developed in record time. Despite the h istoric success of the mRNA vaccines\, additional research is needed to fu rther understand the underlying mechanisms of protection. While many studi es focus primarily on antibody neutralization titers\, another aspect of h umoral immunity that is often overlooked is antibody avidity. Avidity\, th e total binding strength of all interactions between an antibody and antig en\, is important to consider in the context of vaccination because it pro vides an important measure of antibody maturation and development. In this study\, I am attempting to characterize antibody avidity in response to v accination. Specifically\, I am exploring differences in avidity maturatio n in SARS-CoV-2 naïve and convalescent populations.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:327@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220209T120000 DTEND;TZID=Pacific/Honolulu:20220209T130000 DTSTAMP:20220203T015529Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarfemal e-genital-schistosomiasis-hiv-infertility-and-cervical-cancer-samantha-gab rielle-morgan-ms-student SUMMARY:TRMD 690 Seminar:”Female Genital Schistosomiasis: HIV\, Infertili ty\, and Cervical Cancer”\, Samantha Gabrielle Morgan\, MS Student DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode\n\nSamantha Gabrielle Morgan\nDept. Of Tropical Medicine\, Medic al Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, Unive rsity of Hawaii at Manoa\n\n\n\n\nFemale Genital Schistosomiasis affects r oughly 50 million women and girls in sub-Saharan Africa\, causing pain and symptoms commonly mistaken for STI infection.  Caused by embedding of Sc histosoma haematobium eggs within genital tissue\, the condition begins in childhood and causes irreversible damage to the tissues\, making them sig nificantly easier to perforate.  This pliability results in increased cha nces of HIV infection.  The calcification of the fallopian tubes and uter ine wall severely reduce the chances of a successful pregnancy\, and many affected women experience ectopic pregnancies.  Finally\, there are sever al factors which correlate FGS with cervical cancer\, including increasing the likely of HPV to establish itself and trigger malignancy. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:326@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220202T120000 DTEND;TZID=Pacific/Honolulu:20220202T130000 DTSTAMP:20220126T013258Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarident ifying-and-repurposing-fda-approved-compounds-to-treat-covid-19-brandon-jo hnson-phd SUMMARY:TRMD 690 Seminar:"Identifying and repurposing FDA-approved compound s to treat COVID-19"\, Brandon Johnson\, PhD DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode\n\nBrandon Johnson\, PhD\nScientist\nCenter for Biomedical Resea rch\nQueen's Medical Center\n\n\n\n\nLong Covid-19 patients endure inflamm atory symptoms including fatigue\, shortness of breath\, and myalgia beyon d thirty days post-infection. Long COVID-19 affects up to 30% of those inf ected with SARS-CoV-2\, and the staggering number of omicron breakthrough infections portends a critical need to develop new strategies to mitigate long-term inflammation. We are taking two approaches to identify novel imm unomodulatory properties of existing FDA-approved drugs that specifically target ion channels. First\, we are developing a high-throughput drug scre en to identify inhibitors of the SARS-CoV-2 envelope (E) protein\, a virus -encoded ion channel that contributes to the cytokine storm in the lungs. Second\, we are evaluating whether the leprosy drug clofazimine has the po tential to suppress hyperinflammation by inhibiting potassium channels cru cial for the activation of autoreactive T cells. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:325@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220126T120000 DTEND;TZID=Pacific/Honolulu:20220126T130000 DTSTAMP:20220121T025454Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminardevel opment-of-microfluidics-for-use-in-a-novel-way-to-characterize-latently-hi v-infected-cells-bradley-mak-ms-student SUMMARY:TRMD 690 Seminar:"Development of Microfluidics for Use in a Novel W ay to Characterize Latently HIV-Infected Cells"\, Bradley Mak\, MS Student DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode\n\nBradley Mak\nTropical Medicine MS Student\nDepartment of Trop ical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Schoo l of Medicine\, University of Hawaii at Manoa\n\n\n\n\nMicrofluidics has n umerous applications in the biomedical field. We aim to develop a low-cost \, microfluidics-based approach (termed HIV-Seek) to isolate\, identify an d characterize latently HIV-infected cells\, which remain poorly understoo d despite being a major barrier to HIV cure. The main challenges to charac terization of this viral reservoir are 1) latently infected cells are rare (frequency of 1/106 resting memory CD4+ T-cells) and 2) activation is req uired to determine latency but also rewires gene expression. Custom microf luidics allows us to perform low-cost experiments to overcome these challe nges. In this presentation\, I will describe the fabrication and basic fun ction of microfluidic devices for use in HIV-Seek. Additionally\, I will b e discussing our progress in integrating microfluidics and molecular biolo gy to develop our novel methodology. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:324@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220119T120000 DTEND;TZID=Pacific/Honolulu:20220119T130000 DTSTAMP:20220110T091742Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarcovid -one-clinical-laboratories-experiences-and-challenges-so-far-impacts-on-re search-stacey-honda-md-phd-kaiser-permanente-hawaii SUMMARY:TRMD 690 Seminar:"COVID – One Clinical Laboratory's Experiences a nd Challenges To Date & Impacts on Research"\, Stacey Honda\, MD\, PhD\, K aiser Permanente-Hawaii DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode\n\nStacey Honda\, MD\, PhD\nAssociate Clinical Professor\, Depar tment of Pathology\, John A Burns School of Medicine\, University of Hawa ii\,\nAssociate Program Director\, University of Hawaii Pathology Residenc y Program\nArea Assistant Medical Director\, Laboratory/Pathology &\; D iagnostic Imaging &\; Research\, Hawaii Permanente Medical Group\, Inc\ nChief of Pathology\, Medical Director of Laboratories &\; Director of Point of Care Testing\, Kaiser Permanente\, Hawaii\nMedical Director\, Cen ter for Integrated Healthcare Research\, Kaiser Permanente Hawaii\n\n\n\n\ nThe early chronology and challenges of one local clinical laboratory will be discussed. The challenges of COVID have been unlike any other and it i s fascinating to look back on where we were\, where we are today and the c ontinuing challenges we face in the clinical laboratory. One aspect of the challenges is the various tests available for COVID and some data will be discussed comparing 2 specific NAAT and Ag assays touching on the researc h aspect of our experiences. While much of the research component touches on the real life\, natural experiments aspect\, a glimpse of the various i mpacts on research as experienced by the presenter will be also discussed. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:323@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20220112T120000 DTEND;TZID=Pacific/Honolulu:20220112T130000 DTSTAMP:20240920T222900Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-acci dental-host-the-story-of-rat-lungworm-disease-film-with-qa SUMMARY:TRMD 690 Seminar: "Accidental Host - The Story of Rat Lungworm Dise ase"\, Film with Q&A DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode\nClaire Panosian Dunavan\, MD\, DTM&\;H (London)\, FIDSA\, FA STMH\, WGA west\nProducer and Principal\nThe HealthQuest Foundation\nPast- President\, American Society of Tropical Medicine and Hygiene Professor Em eritus-Recalled of Medicine and Infectious Diseases\nDavid Geffen School o f Medicine at UCLA\n\nFacilitator:\nKenton Kramer\, PhD\nAssociate Profess or\nDept. of Tropical Medicine\, Medical Microbiology &\; Pharmacology\ nJABSOM\, UH Manoa\n\n\n\n\nThe "Accidental Host" is a medical documentary about a globalizing\, foodborne parasite that invades human brains and no w thrives in tropical areas of five continents\, including Hawaii and the southeastern U.S. This compelling 53-minute film featuring multiple patien t stories and expert interviews shot in Hawaii\, Florida and California de picts a disease that is virtually unknown to most physicians as well as tr avelers and residents at risk. “Accidental Host” was produced by Clair e Panosian Dunavan\, a pastpresident of the American Society of Tropical M edicine and Hygiene and a team of veteran\, award-winning filmmakers.. An interview with the producer can be found at https:// tinyurl.com/2p83cdyr. Time permitting a question and answer session will follow the film.  Dr. Kenton Kramer will facilitate this seminar. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:322@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211208T120000 DTEND;TZID=Pacific/Honolulu:20211208T130000 DTSTAMP:20230530T232336Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarhigh- yield-expression-systems-for-recombinant-antigens-and-antibodies-ludwig-ma yerlen-phd-student SUMMARY:TRMD 690 Seminar:"High yield expression systems for recombinant ant igens and antibodies"\, Ludwig Mayerlen\, PhD Student DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode.\n\nLudwig Mayerlen\nPh.D. Student\nDepartment of Tropical Medic ine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medic ine\, University of Hawaii at Manoa CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:321@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211201T120000 DTEND;TZID=Pacific/Honolulu:20211201T130000 DTSTAMP:20211129T221506Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarrevie w-of-re-emerging-under-recognized-zoonotic-diseases-in-hawaii-rodson-zoril la-ms-student SUMMARY:TRMD 690 Seminar:"Review of Re-emerging\, Under-recognized Zoonotic Diseases in Hawaii"\, Rodson Zorilla\, MS Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcod e\n\nRodson Zorilla\nMS Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\n\n\n\nThe tropical climate and environment al conditions of the Hawaiian Islands provide favorable ecosystems for var ious pathogens\, vectors\, and reservoirs. This creates a conducive enviro nment for transmission of various zoonotic diseases that affect both human s and animals. Wildlife serves as major reservoirs and intermediate hosts for transmission of zoonotic agents to domestic animals and humans. Due to increasing exposure of humans to wildlife\, in the last three decades rep eated outbreaks of zoonotic diseases were reported in Hawaii. This literat ure review will focus on the epidemiological and clinical characteristics of under-recognized emerging zoonoses in Hawaii. Development of an academi c journal database and Geographic Information Systems (GIS) for emerging z oonoses in Hawaii will also be discussed. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:320@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211124T120000 DTEND;TZID=Pacific/Honolulu:20211124T130000 DTSTAMP:20211119T231929Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarhumor al-responses-to-sars-cov-2-vaccine-platforms-in-diabetic-mouse-models-oliv ia-smith-mph SUMMARY:TRMD 690 Seminar:"Humoral responses to SARS CoV-2 vaccine platforms in diabetic mouse models"\, Olivia Smith\, MPH DESCRIPTION:Zoom Details\nMeeting ID: 979 6297 5142\nContact kspedden@hawai i.edu for passcode\n\n\nOlivia Smith\, MPH\nPhD Student\nDepartment of Tro pical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Scho ol of Medicine\, University of Hawaii at Manoa\n\n\n\n\nThe impact of the Coronavirus Disease-19 (COVID-19) pandemic resulted in an unprecedented bu rden to health systems\, caused economic and social disruption\, and led t o a staggering number of deaths. Individuals with Type 2 diabetes mellitus (T2DM) are more susceptible to severe COVID-19\, accounting for 33% of ho spitalizations in the United States\, while those with obesity and morbid obesity\, account for over 60% of the COVID-19 hospitalizations. T2DM affe cts 6.28% of the world’s population and roughly 30 million US Americans. Previous literature suggests reduced vaccine efficacy in individuals with T2DM. Considering how T2DM is a risk factor for severe COVID-19\, it is i mportant to understand how this metabolic syndrome affects the immunity ge nerated by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) va ccines. This seminar will cover the development of a multiplex bead-based using selected variants of the spike glycoprotein and compare the humoral responses elicited by two adjuvanted subunit protein vaccines and an mRNA vaccine in various mouse models including conditions of diabetes and obesi ty. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:319@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211117T120000 DTEND;TZID=Pacific/Honolulu:20211117T130000 DTSTAMP:20211117T081329Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarthe-a nswer-my-friend-is-blowin-in-the-wind-failures-in-public-health-policy-and -messaging-during-the-covid-19-pandemic-tim-brown-east-west-center SUMMARY:TRMD 690 Seminar:"The answer\, my friend\, is blowin’ in the wind ” Failures in public health policy and messaging during the COVID-19 pan demic\, Tim Brown\, East West Center DESCRIPTION:Zoom Link: https://zoom.us/j/97962975142?\nCall in: (669) 900-6 833\nZoom ID: 979 6297 514\nContact kspedden@hawaii.edu for passcode\n\nTi m Brown\, Ph.D.\nSenior Fellow\nEast West Center\nHonolulu\, Hawaii\n\n\n\ nSince even before it was declared a pandemic\, public health policy on CO VID-19 has been poorly thought through\, frequently based on incomplete an d outdated information\, and slow to respond to changes in the pathogen it self. The result has been a set of professed policies and public messaging that in some cases were outright wrong\, have shifted radically over time \, and that have left the public confused while destroying the credibility of many of our “premier” public health institutions. This talk will r eview some of the most serious policy and messaging missteps to date\, loo k at the damage done to responses\, and explore how they have left the pub lic confused and misinformed. Lessons will be drawn from these blunders on how to improve ongoing responses to COVID-19 and better prepare for the n ext variant or pandemic.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:318@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211110T120000 DTEND;TZID=Pacific/Honolulu:20211110T130000 DTSTAMP:20211110T212303Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminara-lit erature-review-on-jellyfish-envenomation-pathophysiology-raechel-kadler-ms -candidate SUMMARY:TRMD 690 Seminar:"A Literature Review on Jellyfish Envenomation & P athophysiology"\, Raechel Kadler\, MS Candidate DESCRIPTION:Zoom Meeting ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode.\n\nRaechel Kadler\nM.S. Candidate\nDepartment of Tropical Medic ine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medic ine\nUniversity of Hawaii at Manoa\n\n\n\nCubozoan jellyfish envenomations are life threatening and a major concern in tropical regions. There are e stimates of 150 million stings worldwide every year\, although under-repor ting is a problem. Certain species\, including Chironex fleckeri\, can cau se cardiovascular collapse and death within minutes. This literature revie w will address the mechanism of envenomation as well as the pathophysiolog y that can lead to death. Additionally\, current in vitro models to recapi tulate envenomation will be discussed. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:316@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211103T120000 DTEND;TZID=Pacific/Honolulu:20211103T130000 DTSTAMP:20211113T010826Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarbiolo gical-parallels-of-the-hiv-and-sars-cov-2-pandemics-discovering-vulnerabil ities-for-intervention-lishomwa-ndhlovu-md-phd SUMMARY:TRMD 690 Seminar:"Biological Parallels of the HIV and SARS-CoV-2 Pa ndemics: Discovering Vulnerabilities for Intervention"\, Lishomwa Ndhlovu \, MD\, PhD DESCRIPTION:Zoom Link: https://zoom.us/j/97962975142\nZoom ID: 979 6297 514 2\nContact cmlum@hawaii.edu for passcode\n\nLishomwa Ndhlovu\, M.D.\, Ph.D .\nProfessor\nDepartment of Tropical Medicine\, Medical Microbiology and P harmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Ma noa\n\n\n\n2021 is the HIV/AIDS pandemics’ 40th anniversary. It has take n hundreds of clinical trials of multiple agents and combinations to achie ve effective treatment—the first triple-drug anti-retroviral therapy (AR T) that worked. Some commentators called it the “Lazarus effect” as pe ople rose from their deathbeds and tamed HIV. Now the HIV latent reservoir represents the major challenge to cure development. Residing in resting C D4+ T cells and myeloid cells at multiple locations in the body\, includin g sanctuary sites such as the brain\, the latent reservoir is not eliminat ed by ART and has the ability to reactivate virus replication to pre-thera py levels when ART is ceased. There is a need to develop new strategies to eradicate the viral reservoir in infected individuals. This presentation will describe progress\, preliminary results\, and lessons learned thus fa r on HIV cure and prevention strategies. With the emergence of third deadl y human coronavirus SARS-CoV-2 (recently identified in China in 2019\, thi s coronavirus has emerged as the latest global pandemic with more than 240 million cases and 4.89 million deaths have been confirmed\, making it one of the deadliest pandemics in history. The spectrum of medical therapies to treat COVID-19 is growing and evolving rapidly and in this presentation I will diverge and present two COVID-19 studies we are undertaking based on lessons learned from the HIV pandemic\, to inform on COVID-19 pathogene sis and treatment and tame this disease.\n\n \;\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:317@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211027T120000 DTEND;TZID=Pacific/Honolulu:20211027T130000 DTSTAMP:20211027T215844Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarinhib ition-of-type-i-ifn-pathway-by-west-nile-virus-ns4a-and-ns4b-proteins-thom as-ken-awamura-ms-student SUMMARY:TRMD 690 Seminar:"Inhibition of Type I IFN Pathway by West Nile Vir us NS4A and NS4B Proteins"\, Thomas Ken Awamura\, MS Student DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode.\ n\nThomas Ken Awamura\nM.S. Student\nDepartment of Tropical Medicine\, Med ical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniv ersity of Hawaii at Manoa\n\n\n\nAs the public health threat of flavivirus es continues to become increasingly prevalent in both tropical and subtrop ical areas of the world\, it has become of increasing interest to study th e interactions between flaviviral proteins and those of our innate immune pathways. In this seminar\, some preliminary data on the interaction of WN V NS4A and NS4B proteins with IKKe and TBK1 of the Type 1 IFN pathway will be discussed. These findings may enhance interest in the targeting of NS4 A and NS4B as potential targets for future antiviral drug development.\n  \n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:315@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211020T120000 DTEND;TZID=Pacific/Honolulu:20211020T130000 DTSTAMP:20211018T064347Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarpartn erships-in-academic-and-community-covid-19-testing-research-puipuia-le-ola -increasing-reach-and-uptake-of-covid-19-testing-among-pacific-islanders-i n-hawaii-and-guam-uh-m SUMMARY:TRMD 690 Seminar:"Partnerships in Academic and Community COVID-19 T esting Research - Puipuia le Ola: Increasing reach and uptake of COVID-19 testing among Pacific Islanders in Hawaii and Guam"\, UH Manoa RADx-UP Pro gram DESCRIPTION:Zoom Link: https://zoom.us/j/97962975142\nCall in: (669) 900-68 33\nZoom ID: 979 6297 5142\nContact kspedden@hawaii.edu for passcode.\n\nR ichard Yanagihara\, M.D.\, M.P.H\nProfessor\, Department of Pediatrics\nDi rector\, Pacific Center for Emerging Infectious Diseases Research\nAngela Sy\, Dr.P.H.\nAssistant Professor\, Department of Tropical Medicine\, Medi cal Microbiology and Pharmacology\nWei-Kung Wang\, M.D.\, Sc.D.\nProfessor \, Department of Tropical Medicine\, Medical Microbiology and Pharmacology \n\n\nPacific Islanders (PI) have among the highest COVID-19-associated mo rbidity and mortality rates nationally. This presentation will describe a community-engaged project\, funded by the Rapid Acceleration of Diagnostic s for Underserved Populations (RADx-UP) program\, to better understand SAR S-CoV-2 infection patterns among PI in Hawaii and on Guam. Culturally and linguistically appropriate strategies may increase uptake of COVID-19 test ing among PI\, resulting in more precise SARS-CoV-2 infection and seroprev alence rates. Community- engagement research methods will involve collabor ating with PI communities to design and implement culturally and linguisti cally appropriate COVID-19 testing strategies. COVID-19 RT-PCR and anti-SA RS-CoV-2 antibody tests are provided for asymptomatic adult PI in Hawaii a nd Guam. Progress\, preliminary results\, and lessons learned thus far on the implementation of culturally resonant community-engagement strategies to increase the reach and uptake of COVID-19 testing will be reported. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:314@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211013T120000 DTEND;TZID=Pacific/Honolulu:20211013T130000 DTSTAMP:20211012T024909Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarafric an-trypanosomes-and-the-human-blood-brain-barrier-insights-and-revelations -and-with-a-bonus-side-track-to-dengue-dennis-grab-phd SUMMARY:TRMD 690 Seminar:"African Trypanosomes and the Human Blood-Brain Ba rrier: Insights and Revelations and with a bonus side-track to dengue"\, D ennis Grab\, PhD DESCRIPTION:Zoom Link: https://zoom.us/j/97962975142\nCall in: (669) 900-68 33\nContact corit@hawaii.edu for passcode.\n \;\nDennis J. Grab\, Ph.D .\nProfessor\nDepartment of Pathology\nUniformed Services University of th e Health Sciences\nBethesda\, Maryland\n \;\n\nHuman African trypanoso miasis (HAT\; commonly called sleeping sickness) is a vector-borne parasit ic disease that has a major impact on human health and welfare in sub-Saha ran countries. Sleeping sickness is caused by two subspecies of African tr ypanosome\, Trypanosoma brucei rhodesiense and T. b. gambiense causing Eas t African and West African sleeping sickness\, respectively. In classical late stage human sleeping sickness the parasites invade the central nervou s system and the infected individuals suffer from progressive neurologic i nvolvement with concomitant psychiatric disorders and\, if untreated\, dea th. In this talk\, I review our progress to delineate the mechanism of Afr ican trypanosome traversal across the human BBB at the molecular and cellu lar levels with the hope that this research will lead to better therapies against the disease caused by this deadly parasite. I will also side-track to a novel dengue therapeutic idea for severe dengue. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:313@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20211006T120000 DTEND;TZID=Pacific/Honolulu:20211006T130000 DTSTAMP:20211005T212106Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarchara cterization-of-circulating-fibrocytes-in-people-living-with-hiv-logan-dean -ms-student SUMMARY:TRMD 690 Seminar:"Characterization of Circulating Fibrocytes in Peo ple Living with HIV"\, Logan Dean\, MS Student DESCRIPTION:Zoom Link: https://zoom.us/j/97962975142\nCall in: (669) 900-68 33\nZoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode\n \; \nLogan Dean\nM.S. Student\nDepartment of Tropical Medicine\, Medical Micr obiology and Pharmacology\nJohn A. Burns School of Medicine\, University o f Hawaii at Manoa\n\n\n\nDue to the success of antiretroviral therapy\, pe ople living with HIV (PLWH) are living longer\, with 51% of PLWH over the age of 50 in the United States. HIV infection and aging independently pred ispose individuals to fibrosis\, an aberrant wound healing response charac terized by excessive extracellular matrix deposition often leading to orga n malfunction. The fibrocyte is a myeloid derived cell type whose increase d numbers have been correlated with severity of fibrotic diseases. Despite their relevance to fibrosis\, studies characterizing the fibrocyte in PLW H are scarce. Thus\, I aimed to design a flow cytometry panel for identify ing fibrocytes in peripheral blood mononuclear cells. Furthermore\, expres sion of fibroblast markers and chemokines associated with recruitment were measured by qPCR using in vitro cultured fibrocytes. Moving forward\, we will analyze resting and activated fibrocyte number as well as phenotypic characterization for comparison between HIV+ individuals and healthy contr ols. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:312@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210929T120000 DTEND;TZID=Pacific/Honolulu:20210929T130000 DTSTAMP:20210925T005229Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminardevel opment-of-strand-specific-pcr-to-detect-replicating-sars-cov-2-in-covid-19 -patients-alanna-tseng-phd SUMMARY:TRMD 690 Seminar:"Development of Strand-Specific PCR to Detect Repl icating SARS-CoV-2 in COVID-19 Patients"\, Alanna Tseng\, PhD DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode.\ n\nAlanna Tseng\, Ph.D.\nJunior Research Scientist\n\nDepartment of Tropic al Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\n\n\n\n\nTesting for sever e acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an essential di agnostic tool for monitoring the ongoing COVID-19 pandemic. Currently\, th e gold standard for the diagnosis of acute SARS-CoV-2 infection is quantit ative reverse transcription polymerase chain reaction (qRT-PCR)\, which is based on nucleic acid amplification technology and targets the genome of SARS-CoV-2. Despite the widespread use of qRT-PCR in clinical settings\, i t cannot differentiate between replicating and non-replicating virus. Ther efore\, we aim to develop a strand-specific qRT-PCR multiplex assay that c an detect both positive- and negative-sense replicating RNA strands that a re synthesized during SARS-CoV-2 infection. With this assay\, we can deter mine the infectiousness of symptomatic and asymptomatic COVID-19 patients and ultimately aid in clinical decision-making for patients who are positi ve for SARS-CoV-2. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:311@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210922T120000 DTEND;TZID=Pacific/Honolulu:20210922T130000 DTSTAMP:20210921T021440Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminardevel opment-and-pre-clinical-efficacy-of-an-adjuvanted-recombinant-subunit-covi d-19-vaccine-albert-to-phd SUMMARY:TRMD 690 Seminar:"Development and pre-clinical efficacy of an adjuv anted recombinant subunit COVID-19 vaccine"\, Albert To\, PhD DESCRIPTION:Zoom ID: 979 6297 5142\nContact cmlum@hawaii.edu for passcode\n Call in: (669) 900-6833\nAlbert To\, Ph.D.\nPostdoctoral Fellow\nDepartmen t of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Bu rns School of Medicine\, University of Hawaii at Manoa\n\n\n\n\n\n\nVaccin ation is a crucial component of an effective public health strategy agains t the ongoing COVID-19 pandemic. FDA-approved and Emergency Use Authorized (EUA) vaccines using new mRNA and viral-vector technology are highly effe ctive in preventing moderate to severe disease\, however information on th eir long-term efficacy and protective breadth against SARS-CoV-2 Variants of Concern (VOC) is currently scarce. This seminar will cover the developm ent and pre-clinical evaluation of an adjuvanted\, recombinant subunit vac cine in mice and cynomolgus macaques. We show that this vaccine is highly immunogenic and induces robust spike-specific and cross-variant neutralizi ng antibodies against circulating VOC for at least 3 months after the fina l boost. Protective efficacy and post-exposure immunity are evaluated usin g a late\, heterologous P.1 (Gamma) challenge model. Our results indicate that our vaccine candidate effectively reduces viral load in the upper &am p\; lower respiratory tract and seems protective against disease in macaqu es even as vaccine immunity wanes. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:310@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210915T120000 DTEND;TZID=Pacific/Honolulu:20210915T130000 DTSTAMP:20210914T190035Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-viro logic-and-bioinformatic-analysis-of-sars-cov-2-to-facilitate-evidence-base d-public-policy-david-maison-tropical-medicine-phd-student SUMMARY:TRMD 690 Seminar: "Virologic and Bioinformatic Analysis of SARS-CoV -2 to Facilitate Evidence-Based Public Policy"\, David Maison\, Tropical M edicine PhD Student DESCRIPTION:\nZoom ID: 979 6297 5142\n\n\n\nContact cmlum@hawaii.edu for pa sscode\n\n\n\nDavid Maison\, M.S.\n\n\n\nPh.D. Student\n Department of Tro pical Medicine\, Medical Microbiology and Pharmacology \nJohn A. Burns Sch ool of Medicine\, University of Hawaii at Manoa\n\n\n\nThe COVID-19 pandem ic has ravaged the world and the global economy. Precision public health g enomics and evidence-based public policy are the proven tools to move our state\, nation\, and the world forward. To implement said tools\, we first characterized the SARS-CoV-2 spike gene to identify mutations and perform phylogenetic tracking. We evaluated mutations against the amassed worldwi de sequencing data and developed a statistical analysis tool to predict em ergence. Next\, we included the reported worldwide SARS-CoV-2 whole genome sequences. Using phylogenetic analysis\, we demonstrate that the majority (76%) of SARS-CoV-2 variants of concern (VOC) introduced to Hawaii are en tering by way of California\, USA. Conclusively\, we demonstrate the signi ficant effect of quarantine in delaying the spread of VOC at both a state and national level. These tools and data provide the foundation for policy -makers and public-health officials to apply precision public health genom ics to real-world policies.\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:309@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210908T120000 DTEND;TZID=Pacific/Honolulu:20210908T130000 DTSTAMP:20210903T064658Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=career-development-se minar-from-tropical-medicine-research-to-global-health-yukie-lloyd-phd-jap an-international-cooperation-agency-jica SUMMARY:Career Development Seminar: "From Tropical Medicine Research to Glo bal Health"\, Yukie Lloyd\, PhD\, Japan International Cooperation Agency ( JICA) DESCRIPTION:Zoom Details\nMeeting ID: 979 6297 5142\nContact cmlum@hawaii.e du for passcode\nThis seminar will be pre-recorded.\n \;\nYukie Lloyd\ , Ph.D.\nInfectious Disease Surveillance Expert\nJapan International Coope ration Agency (JICA)\n \;\nDr. Yukie Lloyd is a 2018 graduate of the T ropical Medicine PhD Program who is pursuing a career in global health and international development. Dr. Lloyd’s PhD research provided her with a n opportunity to conduct field research in malaria immunology at the Unive rsity of Yaoundé in Cameroon. After completing her PhD training\, Dr. Llo yd accepted a position with the Japan International Cooperation Agency (JI CA) as Project Formulation Advisor in Dar es Salaam\, Tanzania from 2019-2 021. Starting in October 2021\, Dr. Lloyd will begin an appointment as Exp ert in Infectious Disease Surveillance for JICA in Kinshasa\, Democratic R epublic of Congo. In this seminar Dr. Lloyd will discuss her experiences a nd achievements as a graduate student\, the career decisions that led her to her current work with JICA\, and future projects and opportunities for collaboration with the Department of Tropical Medicine\, Medical Microbiol ogy\, and Pharmacology at John A. Burns School of Medicine. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:308@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210901T120000 DTEND;TZID=Pacific/Honolulu:20210901T130000 DTSTAMP:20210825T015619Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarneutr ophils-and-their-pathologic-roles-in-non-aids-complications-juwon-park-phd SUMMARY:TRMD 690 Seminar:"Neutrophils and their pathologic roles in non-AID S complications"\, Juwon Park\, PhD DESCRIPTION:Zoom Details\nMeeting ID: 979 6297 5142\nContact cmlum@hawaii.e du for passcode\n\nSpeaker:\nJuwon Park\, Ph.D.\nAssistant Researcher\nDep artment of Cell &\; Molecular Biology\nJohn A. Burns School of Medicine \nUniversity of Hawaii at Manoa\n\nNeutrophils and their pathologic roles in non-AIDS complications\nThe immune system is essential to protect the h ost against infection. Neutrophils\, the most abundant leukocytes have bee n considered to be the front-line defender during inflammation and infecti on. They utilize various mechanisms to destroy invading pathogens\, such a s degranulation\, phagocytosis\, and neutrophil extracellular trap (NET). Far beyond their role in host defense\, a growing body of evidence has dem onstrated that neutrophils have pivotal role in immune regulation and infl ammation. In this seminar\, I will share the current knowledge on neutroph ils and disease pathogenesis with a particular emphasis on NET. Also\, I w ill introduce my current research projects in the field of neutrophil biol ogy\; 1) NET forming neutrophils as a potential risk factor for HIV-associ ated cardiovascular disease and 2) Neutrophil heterogeneity in HIV. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:306@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210625T130000 DTEND;TZID=Pacific/Honolulu:20210625T140000 DTSTAMP:20210617T052439Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-awapuhi-lee-scyllo-inositol-and-other-brain-metabolites-in- relation-to-regional-brain-volumes-cognition-and-inflammatory-markers-in-h iv SUMMARY:Tropical Medicine MS Thesis Defense\, Awapuhi Lee: "Scyllo-inositol and other brain metabolites in relation to regional brain volumes\, cogni tion\, and inflammatory markers in HIV" DESCRIPTION:Zoom Details\nLink: https://zoom.us/j/98312940969\nMeeting ID: 983 1294 0969\nContact cmlum@hawaii.edu for passcode.\n \;\nAwapuhi Le e\nTropical Medicine MS Candidate\nDepartment of Tropical Medicine\, Medic al Microbiology and Pharmacology\nJohn A. Burns School of Medicine\, Unive rsity of Hawaii at Manoa\nAbout half of all HIV+ individuals on antiretrov iral therapy (ART) develop cognitive impairment\, which has been related t o brain atrophy\, cerebral metabolites\, and markers of peripheral inflamm ation. Low brain levels of scyllo-inositol (sI) were linked to lower neuro psychological (NP) test scores in an HIV+ sample with mild-to-moderate cog nitive impairment. To elucidate the roles of sI and other metabolites in H IV-related cognitive dysfunction\, we examined cross-sectional association s between brain metabolites\, regional brain volumes\, NP performance\, an d peripheral blood inflammatory markers in HIV+ individuals on ART. We als o examined metabolite changes before and after initiation of Cenicriviroc or Maraviroc treatment.\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:307@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210623T100000 DTEND;TZID=Pacific/Honolulu:20210623T110000 DTSTAMP:20210617T052354Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-caitlin-williams-advancing-methodologies-to-determine-protective- humoral-responses-generated-by-recombinant-protein-subunit-filovirus-vacci nes SUMMARY:Tropical Medicine PhD Defense\, Caitlin Williams: "Advancing Method ologies To Determine Protective Humoral Responses Generated By Recombinant Protein Subunit Filovirus Vaccines" DESCRIPTION:Zoom Details\nLink: https://us02web.zoom.us/j/87031070234\nMeet ing ID: 870 3107 0234\nFor meeting passcode contact cmlum@hawaii.edu\n\nCa itlin Williams\nPh.D. Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversi ty of Hawaii at Manoa\nFiloviruses are endemic in Tropical Sub-Saharan Afr ica and have caused sporadic and deadly outbreaks in Central and West Afri ca with case fatality rates of up to 90%. The largest Ebola Virus Disease outbreak on record caused over 28\,000 cases.  There is a clear need for  comprehensive disease intervention to prevent future outbreaks. Licensed vaccines\, Ervebo and Zabdeno + Mvabea\, utilize viral vector platforms w hich are contraindicated in pregnant and nursing women. To address the nee ds of special populations with altered immunocompetence\, our lab has deve loped protein subunit vaccines that have shown protection against all thre e filoviruses in non-human primate (NHP) models. There are no known correl ates of protection for any filovirus disease and therefore no defined goal s for what a protective immune response to these vaccines should be compri sed of.  The goal of this project is to study protective antibody respons es in murine and NHP models to understand what aspects of immunity are imp ortant for protection in both the general population as well as during pre gnancy and nursing. We developed methods for analyzing the breadth of anti body responses to our vaccine by utilizing a peptide-array based ImmunoSig nature (IS) as well as investigating the importance of antibody function t hrough avidity and surrogate neutralization assays. To assess maternal imm unization\, we utilized a mouse model to analyze vaccine induced maternal antibody transfer to suckling pups. These experiments enhance our understa nding of humoral immunity and protection against filovirus infection and a s such help advance knowledge in the field of filovirology.\n\n \;\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:305@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210505T120000 DTEND;TZID=Pacific/Honolulu:20210505T130000 DTSTAMP:20210430T200812Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-609-seminarchara cterizing-the-humoral-response-of-a-recombinant-subunit-ebola-virus-vaccin e-aquena-ball-phd-candidate SUMMARY:TRMD 609 Seminar:"Characterizing the Humoral Response of a Recombin ant Subunit Ebola Virus Vaccine"\, Aquena Ball\, PhD Candidate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nContact cmlum@hawaii.edu for passcode\n\nAquen a Ball\nPh.D. Candidate\nDepartment of Tropical Medicine\, Medical Microbi ology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Ha waii at Manoa\nEbola virus (EBOV) causes lethal hemorrhagic fever with cas e fatality rates of up to 90%. Outbreaks are sporadic and unpredictable an d vaccination has been a much-awaited tool to controlling spread of diseas e. However\, due to limited stocks of approved vaccines and requirement of stringent and ultra-cold storage there is a need to continue developing n ew\, more practical vaccine candidates. Although all vaccine candidates us e the surface glycoprotein as the main antigen\, the modality by which pro tection is induced by the EBOV glycoprotein remains unclear. We have devel oped a recombinant subunit vaccine that combines an increased safety profi le with excellent thermostability\, allowing easier deployment in endemic regions. Our vaccine has shown full protection in non-human primates\, how ever\, we have yet to fully characterize the immune responses elicited by our vaccine. Here we analyze the humoral immune response in non-human prim ates immunized with different EBOV subunit GP formulations to guide furthe r vaccine development and provide insights into correlates of protection t hat are still unknown for filoviruses. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:304@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210428T120000 DTEND;TZID=Pacific/Honolulu:20210428T130000 DTSTAMP:20210428T023943Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarinves tigating-the-use-of-ultra-small-iron-oxide-nanoparticles-as-a-subunit-vacc ine-delivery-platform-with-adjuvant-like-properties-aneesa-golshan-phd-can didate SUMMARY:TRMD 690 Seminar:"Investigating the Use of Ultra-Small Iron Oxide N anoparticles as A Subunit Vaccine Delivery Platform with Adjuvant-like Pro perties"\, Aneesa Golshan\, PhD Candidate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nContact cmlum@hawaii.edu for passcode\n \; \n"Investigating the Use of Ultra-Small Iron Oxide Nanoparticles as A Subu nit Vaccine Delivery Platform with Adjuvant-like Properties"\n \;\nAne esa Golshan\nPh.D. Candidate\nDepartment of Tropical Medicine\, Medical Mi crobiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa\n \;\n\nSubunit vaccines have reduced reactogenicit y and are safer for immunosuppressed populations such as the elderly\, pre gnant women\, or the immunocompromised\, however\, they often lack in immu nogenicity and long-term effectiveness. In order to improve upon these vit al qualities\, adjuvants are frequently added to subunit vaccine formulati ons. However\, few FDA-approved adjuvants exist and their mechanisms of ac tion are often poorly understood or limited to specific study conditions. Inorganic nanoparticle delivery systems with built-in adjuvant properties have the potential to address this issue and increase subunit vaccine immu nogenicity without the need for additional adjuvants to be added to vaccin e formulations. Our research indicates that the functionalized iron-oxide nanoparticles possess adjuvant-like properties and are internalized by bon e marrow-derived dendritic cells. The purpose of this research is to eluci date the mechanism of action of functionalized iron oxide nanoparticles of sizes 5 nm\, 10 nm\, 20 nm and 30 nm on the innate immune system\, with a focus on dendritic cells. Overall\, we aim to identify an optimal size of iron oxide nanoparticles for use in subunit vaccines to improve the immun ogenicity of subunit antigens without added adjuvant.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:303@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210421T120000 DTEND;TZID=Pacific/Honolulu:20210421T130000 DTSTAMP:20210420T222557Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarneuro angiostrongyliasis-a-diagnostic-challenge-charmaine-kuehne-ms-candidate SUMMARY:TRMD 690 Seminar:"Neuroangiostrongyliasis: A Diagnostic Challenge"\ , Charmaine Kuehne\, MS Candidate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nContact cmlum@hawaii.edu for passcode\nCharmai ne Kuehne\nM.S. Candidate\nDepartment of Tropical Medicine\, Medical Micro biology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa\nNeuroangiostrongyliasis or rat lungworm disease is a rare and potentially severe neurotropic nematode illness found worldwide\, esp ecially in Hawaiʻi. Parasitic worms are transmitted to humans by consumin g the infectious larvae in the intermediate or paratenic host. Historicall y\, this disease has been challenging to diagnose at an early stage of inf ection. Definitive diagnosis involves performing a lumbar puncture to coll ect cerebrospinal fluid to identify worms that have migrated to the brain or detecting the parasite's DNA by RT-PCR. Clinical diagnosis with a detai led medical history\, finding eosinophils in the CSF\, with or without a p ositive PCR is the recommended diagnostic algorithm. Despite these specifi c clinical guidelines\, delay in diagnosis and treatment initiation still occurs\, which increases the risk of long-term sequelae. I will review pre vious efforts to diagnose this uncommon illness and explore new laboratory tests that may enable earlier diagnosis.\n\n \;\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:302@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210414T120000 DTEND;TZID=Pacific/Honolulu:20210414T130000 DTSTAMP:20210414T040541Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-char acterizing-the-antiviral-activity-of-two-recombinant-interferons-and-a-nov el-class-of-organobismuth-compounds-michael-faundo-ms-candidate SUMMARY:TRMD 690 Seminar: "Characterizing the Antiviral Activity of Two Rec ombinant Interferons and a Novel Class of Organobismuth Compounds"\, Micha el Faundo\, MS Candidate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nContact cmlum@hawaii.edu for passcode\nMichael Faundo\nM.S. Candidate\nDepartment of Tropical Medicine\, Medical Microbi ology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Ha waii at Manoa\nVirus-specific vaccines\, antiviral drugs\, and immunothera peutics are the most powerful tools to combat viral diseases. Type-I inter ferons (IFNs) have become an attractive therapeutic option to control cert ain chronic virus infections such as hepatitis B and C due to their abilit y to modulate the immune responses. Although consisting of 12 different su btypes\, IFN-α2 remains the well characterized and the only one approved for clinical use\, warranting further investigation of other subtypes. Her e we seek to express and isolate two recombinant IFN-α subtypes and asses s their biological activity and their ability to induce an antiviral state . Although conventional molecular biology and tissue culture methods have enabled the practical application of type-I interferons\, synthetic chemis try has also been a driving force for unlocking the potential of certain c ompounds\, such as bismuth. Bismuth salts are known for their low amounts of toxicity and chemical potential of bismuth and bismuth compounds have b een actively exploited in recent years. Historically used before the adven t of modern antibiotics and continues to be relevant in treating several g astrointestinal disorders\, the potential of organobismuths compounds rema ins to be elucidated. The focus of this research is to evaluate the potent ial antiviral activity of this entirely new class of compounds.\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:301@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210407T120000 DTEND;TZID=Pacific/Honolulu:20210407T130000 DTSTAMP:20210402T021946Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarhiv-s eek-microfluidic-based-isolation-and-characterization-of-latently-hiv-infe cted-cells-bradley-mak-trmd-ms-candidate SUMMARY:TRMD 690 Seminar:"HIV-Seek: Microfluidic-based Isolation and Charac terization of Latently HIV-Infected Cells"\, Bradley Mak\, TRMD MS Candid ate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nContact cmlum@hawaii.edu for passcode\n"HIV-Se ek: Microfluidic-based Isolation and Characterization of Latently HIV-Infe cted Cells"\n\nBradley Mak\nM.S. Candidate\nDepartment of Tropical Medicin e\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicin e\nUniversity of Hawaii at Manoa\nMicrofluidics has numerous applications in the biomedical field. We aim to develop a low-cost\, microfluidics-base d method (HIV-Seek) to identify and characterize latently HIV-infected T-c ells. The main challenges are 1) latent infection occurs at a frequency of one in a million in resting memory CD4+ T-cells in antiretroviral-treated individuals\, and 2) activation is required to determine latency. Microfl uidics presents an ideal platform by which these obstacles can be overcome . In this presentation\, I will discuss my research with microfluidic devi ces for application in HIV-Seek. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:300@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210331T120000 DTEND;TZID=Pacific/Honolulu:20210331T130000 DTSTAMP:20210331T220827Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-hiv- seek-preparation-of-hiv-rna-specific-binding-beads-for-microfluidic-applic ation-eduardo-gamez-trmd-ms-candidate SUMMARY:TRMD 690 Seminar: HIV Seek: "Preparation of HIV RNA-specific bindin g beads for microfluidic application"\, Eduardo Gamez\, TRMD MS Candidate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nPlease contact cmlum@hawaii.edu for passcode\n Eduardo Gamez\nM.S. Candidate\nDepartment of Tropical Medicine\, Medical M icrobiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa\nIntegration of the viral genome into CD4+ T-cells is a hallmark of human immunodeficiency virus (HIV). The ability of HIV to es tablish a latent infection is a major barrier for eliminating the virus fr om infected individuals. Detailed characterization of patient-derived HIV- infected cells is technically challenging because of their scarcity and a lack of protein biomarkers. Therefore\, we are developing a new method to identify and characterize infected T cells to better understand the mechan isms by which they exist. This method\, named HIV-Seek\, utilizes microflu idics to isolate and determine the transcriptomes of HIV-infected T cells. In this presentation\, I will discuss my initial efforts on the developme nt of HIV-Seek\, including preparing microscopic beads that are able to bi nd to RNA. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:299@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210324T120000 DTEND;TZID=Pacific/Honolulu:20210324T130000 DTSTAMP:20210323T181627Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarserop revalence-and-continuous-transmission-of-west-nile-virus-among-female-sex- workers-in-senegal-between-1991-and-1999-samantha-morgan-phd-candidate SUMMARY:TRMD 690 Seminar:"Seroprevalence and Continuous Transmission of Wes t Nile virus Among Female Sex Workers in Senegal Between 1991 and 1999"\, Samantha Morgan\, PhD Candidate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nContact cmlum@hawaii.edu for passcode\nSamanth a Morgan\n\n\n\nPh.D. Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversi ty of Hawaii at Manoa\n\n\n\n\nWest Nile Virus (WNV) is a member of the fa mily Flaviviridae endemic in several African countries\, including Senegal .  Animal seroprevalence studies for WNV have been conducted\, but the se roprevalence and transmission in humans remains elusive.  Using western b lot analysis\, serum from 109 female sex workers were tested for flaviviru s reactivity\, and 26 of them demonstrated antibodies to the WNV prM prote in.  For these individuals\, serum from blood draws 6 to 36 months prior to the original blood draw were then tested first with western blot and th en with ELISA to identify two seroconversions between 1991 and 1999.  The seroprevalence of WNV was found to be 11.0%\, and the seroconversion rate was 0.8% during this period\, demonstrating a continuous transmission of WNV in the region.\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:298@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210310T120000 DTEND;TZID=Pacific/Honolulu:20210310T130000 DTSTAMP:20210309T025413Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-seminaridentific ation-and-implications-of-hiv-1-subtype-crf01_ae-in-hawaii-logan-dean-trmd -ms-candidate SUMMARY:TRMD Seminar:"Identification and Implications of HIV-1 Subtype CRF0 1_AE in Hawaii"\, Logan Dean\, TRMD MS Candidate DESCRIPTION:\n\n\n\nZoom Details\nLink: https://zoom.us/j/94805199979\nMeet ing ID: 948 0519 9979\nFor passcode\, contact cmlum@hawaii.edu\n\nLogan De an\nM.S. Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology John A. Burns School of Medicine\nUniversity of Hawaii a t Manoa\nHuman Immunodeficiency Virus (HIV) has a high propensity for gene tic variation\, demonstrated by its complex phylogeny and multiplicity of types and subtypes. Subtype B is predominant in North America while CRF01_ AE is found in over 50% of cases in the Philippines and Southeast Asia. Ha waii’s geographic location and heavy tourism industry allows for potenti al subtype exchange between Southeast Asia and North America. The Hawaii C enter for AIDS (HICFA) launched a collaborative study with Philippines Gen eral Hospital to compare clinical and neurologic differences by site betwe en HIV positive and HIV negative participants. Since subtype differences h ave an impact on clinical and neurological outcomes\, molecular phylogenet ic subtyping was conducted on HIV+ blood samples. 2 (13%) of HIV+ particip ants in the Hawaii cohort were identified as having subtype CRF01_AE. One of these participants emigrated from the Philippines while the other was b orn and raised in Hawaii. To our knowledge this is the first study that re veals CRF01_AE subtype infection in a born and raised Hawaii resident. Cli nical and public health implications will be discussed\, as well as subtyp e differences that influence treatment success\, disease progression\, and potential cure strategies.\n\n \;\n\n\n\n\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:297@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210303T000000 DTEND;TZID=Pacific/Honolulu:20210303T130000 DTSTAMP:20210302T020918Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-609-seminar-a-re combinant-protein-subunit-filovirus-vaccine-induces-passive-protection-thr ough-transfer-of-maternal-antibody-caitlin-williams-tropical-medicine-phd- candidate SUMMARY:TRMD 609 Seminar: "A Recombinant Protein Subunit Filovirus Vaccine Induces Passive Protection Through Transfer of Maternal Antibody"\, Caitli n Williams\, Tropical Medicine PhD Candidate DESCRIPTION:\nZoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900- 6833\nZoom ID: 948 0519 9979\nFor passcode contact clum@hawaii.edu\n\n\n\n \nCaitlin Williams\, Ph.D. Candidate\n\n\nDepartment of Tropical Medicine\ , Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\ nUniversity of Hawaii at Manoa\n\n\n \;\n\nFiloviridae is a family of negative sense single stranded RNA viruses capable of causing severe hemor rhagic fevers in humans and non-human primates. These viruses are recovere d in several bodily fluids. Breastmilk may be a mechanism of mother to chi ld transmission as Zaire ebolavirus has been detected by both culture and RT-PCR after seroreversion in the blood. Nursing infants with infected mot hers contracted Ebola Virus Disease (EVD) in 80% of the cases studied. Ebo la RNA was detectable in amniotic fluids well after serum clearance in the mother\, indicating transplacental viral transmission as well. Lack of ma ternal protection during natural infection highlights the need for vaccine induced immunity to protect women and nursing infants in Ebola endemic re gions. Development of a vaccine to induce passive immunization is key to p rotecting neonates from EVD. Maternal IgG is transferred to neonates at hi gh concentrations in utero as well as through nursing. Our group has devel oped a recombinant protein subunit vaccine with protective efficacy in mic e. We demonstrated that a filovirus protein subunit vaccine induces potent humoral responses in adult female mice that are efficiently transferred t o suckling pups. Antigen specific maternal IgG reaches high titers in the pups and remains in the periphery for several weeks post-weaning\, indicat ing the potential for this platform to provide a comprehensive vaccine opt ion for pregnant and nursing women in Ebola endemic areas. CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:296@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210224T120000 DTEND;TZID=Pacific/Honolulu:20210224T130000 DTSTAMP:20210222T190822Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-long itudinal-processing-of-brain-mri-data-using-freesurfer-software-awapuhi-le e-trmd-ms-candidate SUMMARY:TRMD 690 Seminar: "Longitudinal Processing of Brain MRI Data Using FreeSurfer Software"\, Awapuhi Lee\, TRMD MS Candidate DESCRIPTION:\nZoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900- 6833\nZoom ID: 948 0519 9979\nContact clum@hawaii.edu for passcode\n\n\n\n \n\n\n\n\nAwapuhi Lee\nM.S. Candidate\nDepartment of Tropical Medicine\, M edical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUn iversity of Hawaii at Manoa\n\n\n"Longitudinal Processing of Brain MRI Dat a Using FreeSurfer Software"\n\n\n\nDespite effective antiretroviral thera py\, neurocognitive impairment in HIV disease is a public health issue as it may affect 40-70% of HIV+ individuals. Brain atrophy that exceeds norma l age-related volumetric loss has been associated with cognitive impairmen t in HIV. Using brain magnetic resonance imaging data from the Hawaiʻi Ce nter for AIDS Cenicriviroc (CVC) and Maraviroc (MVC) studies\, we aim to i dentify brain metabolites and peripheral blood inflammatory markers that m ay be cross-sectionally related to smaller brain volumes. Additionally\, w e will examine possible effects of CVC and MVC on brain volumetric change. To quantify brain atrophy\, we utilize FreeSurfer\, a software tool that segments gray and white matter and generates measures of brain morphometry (e.g.\, volumes of cortical and subcortical regions). FreeSurfer’s long itudinal processing method is divided into four steps: 1) processing each time point cross-sectionally\; 2) creating an unbiased template from all t ime points\; 3) processing each time point longitudinally\; and 4) inspect ing results and conducting statistical analyses.\n\n \;\n\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:295@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210210T120000 DTEND;TZID=Pacific/Honolulu:20210210T130000 DTSTAMP:20210207T031101Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminardevel opment-of-an-rna-based-prognosis-model-of-native-hawaiians-with-colorectal -cancer-scott-bowler-phd-candidate SUMMARY:TRMD 690 Seminar:"Development of an RNA-based Prognosis Model of Na tive Hawaiians with Colorectal Cancer"\, Scott Bowler\, PhD Candidate DESCRIPTION:Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900-68 33\nZoom ID: 948 0519 9979\nContact molivry@hawaii.edu for passcode.\n\n"D evelopment of an RNA-based Prognosis Model of Native Hawaiians with Colore ctal Cancer"\nScott Bowler\nPh.D. Candidate\nDepartment of Tropical Medici ne\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medici ne\nUniversity of Hawaii at Manoa\nColorectal cancer (CRC) is the third mo st diagnosed cancer and the second leading cause of cancer-related deaths in the US. Native Hawaiian (NH) males have low incidence of CRC\, but the highest CRC-related mortality rates among any racial demographic. In this study\, we compared 41 NH with CRC with healthy people and compared RNA se quencing data to available data from The Cancer Genome Atlas (TCGA). Diffe rential gene expression analysis revealed 1\,739 uniquely expressed genes in the NH cohort. A prognostic multivariable cox proportional hazards mode l with stepwise fitting generated a prognostic index. Individuals with a & lt\;median prognostic index had significantly improved survival in the NH cohort (logrank p-value=3.6E-5). When adjusted for age\, gender\, and tumo r grade\, prognostic index was shown to have predictive value (hazard rati o 18.17\, p-value=0.005). This study has identified RNA expression profile unique to a Native Hawaiian population\, which may aid patients and care givers in making informed decisions and identify potential therapeutic tar gets to improve patient outcomes.\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:294@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210127T120000 DTEND;TZID=Pacific/Honolulu:20210127T130000 DTSTAMP:20230530T232425Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-609-seminarhigh- yield-expression-systems-for-recombinant-antigens-and-antibodies-ludwig-ma yerlen-phd-candidate SUMMARY:TRMD 609 Seminar:"High yield expression systems for recombinant ant igens and antibodies"\, Ludwig Mayerlen\, PhD Candidate DESCRIPTION:\nZoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900- 6833\nZoom ID: 948 0519 9979\nContact molivry@hawaii.edu for passcode.\n"H igh yield expression systems for recombinant antigens and antibodies"\n\nL udwig Mayerlen\n\nPh.D. Candidate\nDepartment of Tropical Medicine\, Medic al Microbiology and Pharmacology\n\n\nJohn A. Burns School of Medicine\nUn iversity of Hawaii at Manoa\n \;\n\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:293@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210120T120000 DTEND;TZID=Pacific/Honolulu:20210120T130000 DTSTAMP:20210115T015527Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-sars -cov-2-biology-and-countermeasure-development-dr-pei-yong-shih-university- of-texas-medical-branch-galveston SUMMARY:TRMD 690 Seminar: SARS-CoV-2 Biology and Countermeasure Development \, Dr. Pei-Yong Shih\, University of Texas Medical Branch\, Galveston DESCRIPTION: Zoom Link: https://zoom.us/j/94805199979\nCall in: (669) 900- 6833\nZoom ID: 948 0519 9979\nEmail molivry@hawaii.edu for passcode.\n"SAR S-CoV-2 Biology and Countermeasure Development"\nI will present two COVID- 19 studies. (i) We have developed a reverse genetic system and reporter vi rus for SARS-CoV-2. These genetic tools have been used for serodiagnosis\, vaccine\, and antiviral development. Using a reporter SARS-CoV-2-based ne utralization assay\, we have supported the preclinical development and pha se 1/2 clinical trials of Pfizer/BioNTech’s vaccine\, leading to the fir st COVID-19 vaccine with 95% efficacy in humans\; (ii) We recently showed that spike D164G substitution\, which became dominant over the course of p andemic\, significantly enhances viral replication in primary human airway cultures. When infecting hamsters\, the D164G mutation increased viral fi tness in the upper respiratory tract\, but not in the lungs\, supporting t he increased potential for viral transmission.\nPei-Yong Shi\, Ph.D.\nJohn Sealy Distinguished Chair in Innovations in Molecular Biology\nVice Chair for Innovation and Commercialization\nDepartment of Biochemistry &\; M olecular Biology\nUniversity of Texas Medical Branch at Galveston CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:292@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20210113T120000 DTEND;TZID=Pacific/Honolulu:20210113T130000 DTSTAMP:20210113T183845Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-health-chall enges-in-the-pacific-before-and-during-coronavirus-pandemic-admiral-louis- tripoli-m-d SUMMARY:TRMD 690: "Health Challenges in the Pacific Before and During Coron avirus Pandemic"\, Admiral Louis Tripoli\, M.D. DESCRIPTION:TRMD 690\n\n\nWednesday\, January 13\, 2021 via Zoom @ 12:00 PM - 1:00 PM\n\n\n \n\nZoom Link: https://zoom.us/j/94805199979\nCall in: ( 669) 900-6833\nZoom ID: 948 0519 9979\nPasscode: 539158\n\n"Health Challen ges in the Pacific Before and During Coronavirus Pandemic"\n\nThis present ation reviews actions taken by US Pacific Command leadership to preserve m ission integrity during the coronavirus pandemic from January 2020 until S eptember 2020.  The three key elements of a successful outcome involved:\ n\n Leadership delivering clear messaging\n2. A continuous learning proce ss\n3. Technological innovation\n\nThe largely successful response of the military in the Pacific to the coronavirus pandemic threat contrasts with the unsuccessful efforts in the continental United States and elsewhere.  As effective vaccines start to become available\, the lessons learned from the military’s actions in the Pacific theater in 2020 may be a useful e xample for others. The coronavirus pandemic is far from over. The manifest ations of this virus have defied predictions by experts\, a situation that is likely to continue. Potential obstacles to eradication have already a risen\, including vaccine resistance among members of the population and i nevitable viral mutations\, facilitated by the large numbers of infected p ersons as a result of unsuccessful mitigation efforts.\n\nAdmiral Louis Tr ipoli\, M.D.\n\nClinical Associate Professor of Medicine\nUniformed Servic es University of Health Sciences\n\nCommand Surgeon\, U.S. Navy CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:291@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201210T123000 DTEND;TZID=Pacific/Honolulu:20201210T133000 DTSTAMP:20201201T203128Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-for-boonyanudh-jiyarom-defining-role-of-different-virus-sen sing-pathways-in-modulating-zikv-replication-in-human-sertoli-cells SUMMARY:Tropical Medicine MS Thesis Defense for Boonyanudh Jiyarom: "Defini ng role of different virus sensing pathways in modulating ZIKV replication in human Sertoli cells" DESCRIPTION:Zoom Link: https://zoom.us/j/95235329497\nZoom ID: 952 3532 949 7 \nContact molivry@hawaii.edu for passcode\n\nCall-in phone numbers: (669 ) 900-6833 or (253) 215-8782\n\nM.S. Thesis Defense\n \n\n"Defining role of different virus sensing pathways in modulating ZIKV replication in huma n Sertoli cells"\nBoonyanudh Jiyarom\n\nM.S. Candidate\nDepartment of Trop ical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns Schoo l of Medicine\, University of Hawaii at Manoa CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:290@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201209T120000 DTEND;TZID=Pacific/Honolulu:20201209T130000 DTSTAMP:20201207T182440Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-inse ct-cell-expressed-recombinant-viral-glycoproteins-are-effective-immunogens -albert-to-trmd-phd-candidate SUMMARY:TRMD 690 Seminar & PhD Defense: "Insect Cell-Expressed Recombinant Viral Glycoproteins are Effective Immunogens"\, Albert To\, TRMD PhD Candi date DESCRIPTION:Zoom Link:  https://zoom.us/j/94880253678\nCall in: (669) 900- 6833\nZoom ID: 948 8025 3678\nContact molivry@hawaii.edu for passcode\n&nb sp\;\nInsect Cell-Expressed Recombinant Viral Glycoproteins are Effective Immunogens\n \;\nAlbert To\n\nPh.D. Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:289@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201202T120000 DTEND;TZID=Pacific/Honolulu:20201202T130000 DTSTAMP:20201125T191902Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarinhib ition-of-type-i-ifn-pathway-by-flaviviral-ns4a-and-ns4b-proteins-thomas-aw amura-trmd-ms-student SUMMARY:TRMD 690 Seminar:"Inhibition of Type I IFN Pathway by Flaviviral NS 4A and NS4B Proteins"\, Thomas Awamura\, TRMD MS Student DESCRIPTION:Zoom Link:  https://zoom.us/j/94880253678\nCall in: (669) 900- 6833\nZoom ID: 948 8025 3678\nContact molivry@hawaii.edu for passcode\n&nb sp\;\nInhibition of Type I IFN Pathway by Flaviviral NS4A and NS4B Protein s\n \;\nThomas Awamura\n\nM.S. Student\nDepartment of Tropical Medicin e\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicin e\nUniversity of Hawaii at Manoa\n \;\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:288@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201125T120000 DTEND;TZID=Pacific/Honolulu:20201125T130000 DTSTAMP:20201125T184932Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-trmd-690-semina r-marine-pollution-human-wellbeing-and-health-catherine-pirkle-phd-office- of-public-health-studies SUMMARY:COBRE/TRMD 690 Seminar: "Marine Pollution\, Human Wellbeing and Hea lth"\, Catherine Pirkle\, PhD\, Office of Public Health Studies DESCRIPTION:Zoom Link:  https://zoom.us/j/94880253678\nCall in: (669) 900- 6833\nZoom ID: 948 8025 3678\nContact molivry@hawaii.edu for passcode\n&nb sp\;\n\nMarine Pollution\, Human Wellbeing and Health\nLinkages between oc ean pollution and human health and wellbeing will be discussed\, by using four examples: coral bleaching and economic losses\; dead zones and food i nsecurity\; marine debris\, especially plastics\, and food safety\; and tr ace elements and neurotoxicity. While there are many more examples of link ages between marine pollution and indicators of human health\, the purpose of this presentation is to introduce the concept of how environmental pol lution and damage to the ocean environment affects people in concrete ways \, ranging from their daily livelihoods to their children’s neurodevelop ment.\n\nCatherine M. Pirkle\, Ph.D.\nAssociate Professor\nOffice of Publi c Health Studies\nMyron B. Thompson School of Social Work\nUniversity of H awaii at Manoa CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:287@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201118T120000 DTEND;TZID=Pacific/Honolulu:20201118T130000 DTSTAMP:20201118T093510Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-deve lopment-of-multiplex-serological-assay-by-olivia-smith-tropical-medicine-p hd-student SUMMARY:TRMD 690 Seminar: "Development of multiplex serological assay" by O livia Smith\, Tropical Medicine PhD Student DESCRIPTION:\nZoom Link:  https://zoom.us/j/94880253678\nCall in: (669) 90 0-6833\nZoom ID: 948 8025 3678\nContact molivry@hawaii.edu for passcode\n  \n"Development of multiplex serological assay"\n \;\nOlivia Smith\nP h.D. Candidate\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at M anoa\n END:VEVENT BEGIN:VEVENT UID:286@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201104T120000 DTEND;TZID=Pacific/Honolulu:20201104T130000 DTSTAMP:20201030T040115Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-besi des-poop-wastewater-for-unbiased-and-rapid-community-health-information SUMMARY:TRMD 690 Seminar: "Besides Poop: Wastewater for Unbiased and Rapid Community Health Information"\, Prof. Tao Yan\, UH Manoa DESCRIPTION:\nZoom Link:  https://zoom.us/j/94880253678\nCall in: (669) 90 0-6833\nZoom ID: 948 8025 3678\nContact molivry@hawaii.edu for passcode.\n Dr. Tao Yan\, Ph.D.\nProfessor of Civil and Environmental Engineering\nUni versity of Hawaii at Manoa\n"Besides Poop: Wastewater for Unbiased and Rap id Community Health Information"\nMunicipal wastewater systems (MWSs)\, in cluding the collection and treatment systems\, play a critical role in pub lic health protection by safely collecting\, treating and disposing of hum an wastes. The fact that MWSs collect wastewater from every household of a community to centralized locations also provide an unparalleled sampling instrument for the detection and understanding of community health issues and problems. This talk will first present research results from several p revious studies that explored the potential of the proposed wastewater-bas ed public health surveillance system\, including synchronous detection of pathogen strains in wastewater and clinics\, detection of a clinically-unr eported disease outbreak\, genomic understanding of a group of subclinical pathogen strains\, and prevalence and genetic diversity of a non-notifiab le microbial pathogen. Ongoing research on respiratory viral pathogens\, i ncluding SARS-CoV-2 and influenza\, will also be briefly discussed.\n\n\n\ n\n\n\n\n \nSeminar Schedule located at: http://manoa.hawaii.edu/tropical medicine\n\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:285@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201028T120000 DTEND;TZID=Pacific/Honolulu:20201028T130000 DTSTAMP:20201027T052017Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-char acterization-of-cross-reactive-antibodies-to-dengue-and-zika-viruses-in-pr egnant-women-during-the-zika-outbreak-in-brazil-kaitlin-driesse-tropical-m edicine-phd-student SUMMARY:TRMD 690 Seminar: "Characterization of cross-reactive antibodies to dengue and Zika viruses in pregnant women during the Zika outbreak in Bra zil"\, Kaitlin Driesse\, Tropical Medicine PhD Student DESCRIPTION:\nZoom Link:  https://zoom.us/j/94880253678\nCall in: (669) 90 0-6833 or (877) 853-5247\nZoom ID: 948 8025 3678\nContact molivry@hawaii.e du for passcode.\n \n"Characterization of cross-reactive antibodies to de ngue and Zika viruses in pregnant women during the Zika outbreak in Brazil "\n\nKaitlin Driesse\nPh.D. Candidate\nDepartment of Tropical Medicine\, M edical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\n\n University of Hawaii at Manoa CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:284@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201021T120000 DTEND;TZID=Pacific/Honolulu:20201021T130000 DTSTAMP:20201020T225907Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-radi ation-inactivated-virus-vaccines-and-antiviral-therapeutics-dr-anuj-sharma -uniformed-services-university-of-health-sciences SUMMARY:TRMD 690 Seminar: “Radiation-inactivated-virus vaccines and antiv iral therapeutics”\, Dr. Anuj Sharma\, Uniformed Services University of Health Sciences DESCRIPTION:Zoom Link:  https://zoom.us/j/94880253678\nCall in: (669) 900 -6833 or (877) 853-5247\nZoom ID: 948 8025 3678\nContact cmlum@hawaii.ed u for passcode.\n“Radiation-inactivated-virus vaccines and antiviral the rapeutics”\nAnuj Sharma\, Ph.D.\nAdjunct Assistant Professor/Scientist-I nvestigator\nUniformed Services University of Health Sciences/Office of Re search IntegrityRockville\, MarylanVaccines against viral pathogens are cr itical and most effective prophylactic tools. However\, conventional inact ivation strategies are limited by the poor efficacy of inactivation as wel l as the preservation of virus epitopes. Ionizing radiations can completel y inactivate the virus\, however\, the high-energy radiations can destroy the viral proteins needed to induce protective immune response. A novel lo w-molecular weight manganese containing antioxidant complex protects prote ins from damage by ionizing radiations. Virus irradiated with high doses o f gamma radiation in the presence of manganese complex retained immunogeni city and elicited protective immunity. Another aspect of virus infection i s its interaction with host cellular machinery\, which governs the final o utcome of virus infection. A careful study of these interactions can ident ify key host factors that are amenable targets of therapy for treating vir us infection. At the end of this talk students will learn a novel approach for generating inactivated-viral vaccines and applying knowledge of host- virus interactions to develop effective antiviral therapeutics\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:283@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201014T120000 DTEND;TZID=Pacific/Honolulu:20201014T130000 DTSTAMP:20201009T002425Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=5398 SUMMARY:TRMD 690 Seminar: "AcanR3990\, a new and improved qPCR to detect Ra t Lungworm"\, William Sears\, MD\, MHS\, NIAID Laboratory of Parasitic Dis ease DESCRIPTION:Zoom Link:  \;https://zoom.us/j/94880253678\nCall in: (669) 900-6833 or (877) 853-5247\nZoom ID: 948 8025 3678\nContact sambridh@hawa ii.edu for passcode\nWilliam Sears MD\, MHS\nLaboratory of Parasitic Disea se\nNational Institute of Allergy and Infectious Diseases\nNational Instit utes of Health\nBethesda\, Maryland\n"AcanR3990\, a new and improved qPCR to detect Rat Lungworm"\nAngiostrongylus cantonensis (Ac)\, Rat Lungworm\, is one of the most common causes of eosinophilic meningitis in the world. AcanR3990 is a novel\, bioinformatically informed qPCR assay to detect Ac . The Ac genome was queried with an algorithm\, RepeatExplorer\, to identi fy highly repeated regions of satellite DNA. qPCR assays were designed aga inst the most highly repeated regions and tested for their analytical sens itivity using Ac genomic DNA. The most sensitive\, AcanR3990\, was then sh ared with researchers throughout the world to assess its specificity. The results of this collaborative effort suggest that AcanR3990 is the most an alytically sensitive assay designed to date\, highly specific\, and improv es detection in environmental and clinical samples when compared to the cu rrently most widely used qPCR which targets the ITS1 region of Ac.\n\n&nbs p\;\n\n \;\n\n \;\nSeminar Schedule located at: http://manoa.hawai i.edu/tropicalmedicine CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:282@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20201007T120000 DTEND;TZID=Pacific/Honolulu:20201007T130000 DTSTAMP:20201006T201029Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-non- tuberculous-mycobacteria-from-hawaii-feral-pigs-and-their-clinical-signifi cance-in-human-macrophages-by-haley-hendrick-tropical-medicine-ms-student SUMMARY:TRMD 690 Seminar: "Non-tuberculous Mycobacteria from Hawai'i Feral Pigs and their Clinical Significance in Human Macrophages"\, Haley Hendric k\, Tropical Medicine MS Student DESCRIPTION:Wednesday\, October 7\, 2020 via Zoom @ 12:00 PM - 1:00 PM  \;\nZoom Link:  \;https://zoom.us/j/94880253678\nCall in: (669) 900-68 33 or (877) 853-5247\nZoom ID: 948 8025 3678\nContact sambridh@hawaii.edu for passcode.\nNon-tuberculous mycobacteria (NTM) are ubiquitous in the en vironment and cause a wide range of clinical diseases\, from pulmonary inf ections to bacteremia. In the United States\, Hawai'i has the highest rate of NTM infections by several orders of magnitude. This is likely due to s everal factors\, including soil composition and climate. Feral pigs\, whic h are common in Hawai’i\, have previously been shown to harbor several N TM species\, including Mycobacterium porcinum. This presentation will cove r NTM as a pathogen\, as well as the ongoing joint project between Nationa l Jewish Health in Denver and the University of Hawai’i at Manoa investi gating feral pigs as a potential reservoir for human NTM infections.\n\nHa ley Henrick\nM.S. Candidate\nDepartment of Tropical Medicine\, Medical Mic robiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity o f Hawaii at Manoa\nSeminar Schedule located at: http://manoa.hawaii.edu/tr opicalmedicineTRMD \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:281@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200930T120000 DTEND;TZID=Pacific/Honolulu:20200930T130000 DTSTAMP:20200930T071413Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-unde rstanding-sars-cov-2-pathophysiology-from-mechanisms-to-potential-therapeu tic-targets-mukesh-kumar-dvm-phd-georgia-state-university SUMMARY:TRMD 690 Seminar: "Understanding SARS-CoV-2 Pathophysiology: From M echanisms to Potential Therapeutic Targets"\, Mukesh Kumar\, DVM\, PhD\, G eorgia State University DESCRIPTION:Zoom Link:  \;https://zoom.us/j/94880253678\nCall in: (669) 900-6833 or (877) 853-5247\nZoom ID: 948 8025 3678\nPasscode: 637068\n\n& nbsp\;\nMukesh Kumar\, DVM\, MS\, PhD\nAssistant Professor\nDepartment of Biology\nGeorgia State University\nAtlanta\, Georgia\n \;\nCOVID-19\, the disease caused by the new coronavirus\, SARS-CoV-2\, has caused signif icant human and economic burden. The lack of specific therapeutics for COV ID-19 imparts a pressing need to identify the viral and host factors in SA RS-CoV-2 replication and disease outcome. My laboratory is studying the pa thogenic mechanisms underlying the development of respiratory and neurolog ical complications during SARS-CoV-2 infection. Using various SARS-CoV-2 c ell culture and animal models\, we have evaluated its tissue and cellular tropism\, replication competence and immune responses to provide insights into COVID-19 pathogenesis. I will also discuss the efficacy of the Cas13a RNA-based therapy against SARS-CoV-2.\nFor more information\, contact Dr. Vivek Nerurkar (ph. (808) 692-1668\; email: nerurkar@hawaii.edu)\n\nSemin ar Schedule @ http://manoa.hawaii.edu/tropicalmedicine\n\n\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:280@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200923T120000 DTEND;TZID=Pacific/Honolulu:20200923T130000 DTSTAMP:20200919T002940Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-one- health-in-the-time-of-covid-19-sandra-chang-phd-tropical-medicine-richard- yanagihara-md-mph-pediatrics SUMMARY:TRMD 690 Seminar: "One Health in the Time of COVID-19"\, Sandra Cha ng\, PhD\, Tropical Medicine\; Richard Yanagihara\, MD\, MPH\, Pediatrics DESCRIPTION:One Health in the Time of COVID-19\nA Discussion of the UH Mano a Undergraduate Certificate in One Health\nZoom Details\nLink: https://zoo m.us/j/94880253678\nMeeting ID: 948 8025 3678\nContact sambridh@hawaii.edu for passcode\n\n\nSandra Chang\, PhD\nProfessor and Graduate Program Chai r\nDepartment of Tropical Medicine\, Medical Microbiology &\; Pharmacol ogy\nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\n\n\ nRichard Yanagihara\, MD\, MPH\nProfessor\, Department of Pediatrics\nDire ctor Pacific Center for Emerging Infectious Diseases Research\nJohn A. Bur ns School of Medicine\, University of Hawaii at Manoa\n \;\n\nMauli Ol a\, the Hawaiian concept of physical\, spiritual and mental health and of social and cultural wellbeing\, is deeply rooted in the indigenous belief that the health of the individual and the health of the community are inex tricably linked to the health of the environment. Mauli Ola\, thus\, repre sents the intersection between human health\, animal/plant health\, and en vironmental health\, and is the Hawaiian equivalent of One Health. The COV ID-19 pandemic offers an unparalleled opportunity to use a One Health appr oach to address urgent and emergent issues in Hawai‘i and the world\, ra nging from medical management and vaccine prevention\, public health surve illance and mitigation\, economic hardship\, psychosocial disruption\, hea lth disparities\, food security\, as well as pandemic preparedness and res ponse to newly emerging infectious diseases. The John A. Burns School of M edicine is partnering with the Myron B. Thompson School of Social Work\, t he School of Ocean and Earth Science and Technology\, and the College of T ropical Agriculture and Human Resources to develop an interdisciplinary un dergraduate certificate program in One Health.\nFor more information or to be added to the seminar email list contact Dr. Vivek Nerurkar\nphone: (80 8) 692-1668\; email: nerurkar@hawaii.edu\nSeminar Schedule @ http://manoa. hawaii.edu/tropicalmedicine\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:279@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200916T120000 DTEND;TZID=Pacific/Honolulu:20200916T130000 DTSTAMP:20200915T031242Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-repu rposing-and-reformulation-of-drugs-and-pharmaceutical-excipients-for-the-t reatment-of-infectious-diseases-abhijit-date-phd-daniel-k-inouye-college-o f-pharmacy-uh-hilo SUMMARY:TRMD 690 Seminar: "Repurposing and Reformulation of Drugs and Pharm aceutical Excipients for the Treatment of Infectious Diseases"\, Abhijit D ate\, PhD\, Daniel K. Inouye College of Pharmacy\, UH Hilo DESCRIPTION:Zoom Link: \; https://zoom.us/j/94880253678\nCall in: (669) 900-6833 or (877) 853-5247\nZoom ID: 948 8025 3678\nContact sambridh@hawa ii.edu for passcode.\n\n\n \;\nAbhijit Date\, Ph.D.\nAssistant Profess or of Pharmaceutical Sciences\nDaniel K. Inouye College of Pharmacy\nUnive rsity of Hawaii at Hilo\n"Drug repurposing” is a drug development strate gy that focuses on establishing new indications for existing or previously discarded drugs and it has gained significant momentum to develop effecti ve treatment modalities for infectious diseases. In this seminar\, I will elucidate our efforts on the repurposing of drugs and pharmaceutical excip ients for the treatment of infectious diseases. Currently\, we are involve d in the repurposing and reformulation of anthelmintic benzimidazoles for the treatment of cryptococcal meningitis and rat lungworm disease. The hig h crystallinity and extremely low aqueous solubility of anthelmintic benzi midazoles significantly limit their repurposing for the treatment of paras itic infections of the central nervous system (CNS). We have successfully transformed anthelmintic benzimidazoles into benzimidazole ionic liquids\, which unlike anthelmintic benzimidazoles\, could be encapsulated into pol ymeric nanoformulations suitable for oral delivery. We are also involved i n the repurposing of FDA-approved pharmaceutical excipients for the treatm ent of sexually transmitted viral infections. We have shown that polycarbo xylate polymers are capable of inhibiting herpes simplex virus (HSV) in in -vitro prophylactic and therapeutic assays. We are developing topical moda lities based on polycarboxylate nanoparticles containing anti-HSV drugs fo r the enhanced prevention and treatment of genital herpes.\n\n \;\nFor more information\, contact Dr. Vivek Nerurkar (email: nerurkar@hawaii.edu \; phone: (808) 692-1668)\nSeminar Schedule located at: http://manoa.hawai i.edu/tropicalmedicine CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:278@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200909T120000 DTEND;TZID=Pacific/Honolulu:20200909T130000 DTSTAMP:20200909T081453Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-the- lampole-assay-by-david-maison-tropical-medicine-phd-student SUMMARY:TRMD 690 SEMINAR: "The LAMPole Assay"\, by David Maison\, Tropical Medicine PhD Student DESCRIPTION:Zoom Link: https://zoom.us/j/94880253678\nCall in: (669) 900-68 33 or (877) 853-5247\nZoom ID: 948 8025 3678\nContact sambridh@hawaii.edu for passcode\n"The LAMPole Assay"\nLAMPole is the 21st-century evolution o f the enzyme-linked immunosorbent assay (ELISA). As a result of this evolu tion\, the method can not only replace ELISA in the laboratory with fold i ncreases in diagnostic sensitivity but also has the potential to allow phy sicians to diagnose pathogenic diseases in the field at point-of-care. Thi s presentation will cover the primary origination of the technique and ide as. We will explore the assay concepts\, the experiments essential to achi eve the chimera\, and a discussion of uses and potential applications of t he assay in the future.\nDavid Maison\, M.S.\nPh.D. Student\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School of Medicine\nUniversity of Hawaii at Manoa CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:277@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200902T120000 DTEND;TZID=Pacific/Honolulu:20200902T130000 DTSTAMP:20200901T002409Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-loca l-covid-19-update-jabsom-tropical-medicine-response-to-covid-19 SUMMARY:UPDATED: TRMD 690 Seminar "LOCAL COVID-19 UPDATE - JABSOM Tropical Medicine Response to COVID-19" DESCRIPTION:\nDepartment of Tropical Medicine\,\nMedical Microbiology &\ ; Pharmacology\n \;\nTRMD 690 Seminar\n \;\nLOCAL COVID-19 UPDATE: \nJABSOM Tropical Medicine Response to COVID-19\n \;\nVaccine Developm ent\nAxel Lehrer\, PhD\, Associate Professor\n\nAntibody Testing\nWei-Kung Wang\, PhD\, Professor\n\nTropical Medicine Clinical Laboratory\nVivek R. Nerurkar\, PhD\, Professor &\; Chair\n\nTraining Contact Tracers\nSand ra Chang\, PhD\, Professor &\; Graduate Chair\nJoin Zoom Meeting: https ://hawaii.zoom.us/s/95954986859\nMeeting ID: 959 5498 6859\nEmail sambridh @hawaii.edu for passcode.\n\n\n\n\nPhone one-tap:\nUS: +13462487799\,\,959 54986859# or +14086380968\,\,95954986859#\n\n\n\n \;\n\nFor more infor mation\, contact Dr. Vivek Nerurkar (ph. 692-1668\; email: nerurkar@hawaii .edu)\n\n\nNOTE:\nThis seminar is co-sponsored by the Hawaii Immunization Coalition (HIC)\, Hawaii Pacific Health\, and the Department of Tropical M edicine\, Medical Microbiology and Pharmacology at UHM and is \;eligib le for continuing education credits (CE)\, please attachment below if you are interested in accessing these credits.\nCOVID-19 CE CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:276@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200826T120000 DTEND;TZID=Pacific/Honolulu:20200826T130000 DTSTAMP:20200826T195607Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-deta iled-transcriptomic-characterization-of-latently-hiv-infected-cells-by-dr- iain-macpherson SUMMARY:TRMD 690 Seminar: "Detailed Transcriptomic Characterization of Late ntly HIV-Infected Cells" by Dr. Iain MacPherson DESCRIPTION:Zoom Link: https://zoom.us/j/94880253678\nCall in: (669) 900-68 33 or (877) 853-5247\nZoom ID:  \;948 8025 3678\nContact sambridh@hawa ii.edu for passcode\n"Detailed Transcriptomic Characterization of Latently HIV-Infected Cells"\nIain MacPherson\, PhD\nAssistant Professor\nDepartme nt of Tropical Medicine\, Medical Microbiology &\; Pharmacology\nJohn A . Burns School of Medicine\nUniversity of Hawai‘i at Manoa\nLatency is o ne of the major barriers to a functional HIV cure. It is of intense intere st to characterize patient-derived latently HIV-infected cells for the dis covery of biomarkers which can enable targeting strategies. We are taking a high-throughput approach to isolate and characterize latently infected c ells\, the details of which will be described in this seminar.\n \;\nF or more information\, contact Dr. Vivek Nerurkar (ph. (808)692-1668 or ner urkar@hawaii.edu) END:VEVENT BEGIN:VEVENT UID:275@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200723T130000 DTEND;TZID=Pacific/Honolulu:20200723T140000 DTSTAMP:20200723T225826Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=phd-dissertation-defe nse-for-daniel-p-strange-investigating-the-testicular-tropism-of-zika-viru s-using-2d-and-3d-human-tissue-culture-systems SUMMARY:PhD Dissertation Defense for Daniel P. Strange: “Investigating th e testicular tropism of Zika virus using 2D and 3D human tissue culture sy stems” DESCRIPTION:Ph.D. Dissertation Defense\n \;\n \;\n"Investigating th e testicular tropism of Zika virus using 2D and 3D human tissue culture sy stems"\n \;\nDaniel P. Strange\nPh.D. Candidate\nDepartment of Tropica l Medicine\, Medical Microbiology and Pharmacology\nJohn A. Burns School o f Medicine\, University of Hawaii at Manoa\nZoom Meeting Link:\nhttps://zo om.us/j/97256893699?pwd=T0ExVWlYakxLcFhyWjlxMzMvalhkUT09Meeting ID: 972 56 89 3699\nPassword: 437893\n\n\n \;\nCall-in Phone numbers:\n\n \;  \;  \;  \; (669) 900 6833 or (253) 215 8782 END:VEVENT BEGIN:VEVENT UID:274@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200722T083000 DTEND;TZID=Pacific/Honolulu:20200722T093000 DTSTAMP:20200721T231626Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-and-tropical-me dicine-webinar-infectious-diseases-and-the-twists-of-research-and-educatio n-rodolfo-e-begue-md-professor-louisiana-state-university SUMMARY:COBRE and Tropical Medicine Webinar: "Infectious Diseases and the T wists of Research and Education"\, Rodolfo E. Bégué\, MD\, Professor\, L ouisiana State University DESCRIPTION:\n\n\nInfectious Diseases and the Twists of Research and Educat ion\nRodolfo E. Bégué\, M.D.\nProfessor of Pediatrics Louisiana State Un iversity New Orleans\, Louisiana\n \nDr. Rodolfo Bégué is a Professor an d the Division Chief of Infectious Diseases\, in the Department of Pediatr ics\, at Louisiana State University (LSU) Health Science Center\, in New O rleans\, Louisiana. Since getting an MD degree from the Universidad Peruan a Cayetano Heredia School of Medicine\, in Lima\, Peru\, he has held numer ous academic positions in Peru and at LSU. Between 1997 and 2005\, he was an adjunct assistant professor in the Department of Tropical Medicine at T ulane University\, School of Public Health and Tropical Medicine. Dr. Bég ué’s wide-ranging research interests include pediatric infectious disea ses\, rotavirus infections\, immunizations\, vaccine development\, rotavir us virus-like particles (VLPs) in plants (as a vaccine candidate)\, H. pyl ori infection\, and travelers’ health. He has been awarded numerous gran ts\, and sits on a number of NIH review panels. His peer-reviewed publicat ions span multiple infectious agents attesting to his wide and varied rese arch interests.\n\nJoin Zoom Meeting https://zoom.us/j/97870609936\nMeetin g ID: 978 7060 9936\nFor passcode\, email sambridh@hawaii.edu\n\nCall-in: (669) 900-6833 or (253) 215-8782\n\n\n\n\nThis seminar is supported by gra nt P30GM114737 (COBRE) from the National Institutes of Health.\n\n\n\n\n\n \n END:VEVENT BEGIN:VEVENT UID:273@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200604T130000 DTEND;TZID=Pacific/Honolulu:20200604T140000 DTSTAMP:20200515T003516Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-for-thomas-a-premeaux-emerging-challenges-in-hiv-and-aging-role-o f-a-glycan-binding-immunomodulatory-lectin SUMMARY:Tropical Medicine PhD Defense for Thomas A. Premeaux: "EMERGING CHA LLENGES IN HIV AND AGING: ROLE OF A GLYCAN-BINDING IMMUNOMODULATORY LECTIN " DESCRIPTION: \;\n \;\nDepartment of Tropical Medicine\, \nMedical M icrobiology and Pharmacology\n \;\nPhD Dissertation Defense\n \;\n \n\n\n\nEMERGING CHALLENGES IN HIV AND AGING: ROLE OF A GLYCAN-BINDING IMM UNOMODULATORY LECTIN\n\n\n\n\n \;\nThomas A. Premeaux\nPh.D. Candidate \nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\ nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\nThursda y\nJune 4\, 2020 @ 1:00 pm HST\nZoom link:\nhttps://hawaii.zoom.us/j/942-3 998-9447\nMeeting ID: 942 3998 9477\nFor password\, please contact: sambri dh@hawaii.edu\n \;\nFor further information\, contact Dr. Lishomwa Ndh lovu (email: lndhlovu@hawaii.edu)\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:271@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200505T100000 DTEND;TZID=Pacific/Honolulu:20200505T110000 DTSTAMP:20200421T234811Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-for-joanna-kettlewell-effect-of-antiretroviral-therapy-on-blood-b rain-barrier-integrity-and-central-nervous-system-inflammation SUMMARY:Tropical Medicine PhD Defense for Joanna Kettlewell: "Effect of Ant iretroviral Therapy on Blood-brain Barrier Integrity and Central Nervous S ystem Inflammation" DESCRIPTION:\n\n \;\nDepartment of Tropical Medicine\, \nMedical Microb iology and Pharmacology\n \;\nPhD Dissertation Defense\n \;\nEffec t of Antiretroviral Therapy on Blood-brain Barrier\nIntegrity and Central Nervous System Inflammation\n \;\nJoanna M. Kettlewell\nPh.D. Candidat e\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology \nJohn A. Burns School of Medicine\, University of Hawaii at Manoa\nTuesda y\nMay 5\, 2020 @ 10:00am HST\nZoom link:\nhttps://hawaii.zoom.us/j/956599 68770\nMeeting ID: 956 5996 8770\nFor password\, please contact: sambridh@ hawaii.edu\n \;\nFor further information\, contact Dr. Bruce Shiramizu (phone: 692-1677\; email: bshirami@hawaii.edu)\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:272@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200429T120000 DTEND;TZID=Pacific/Honolulu:20200429T130000 DTSTAMP:20200425T023202Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-util izing-defined-structural-subunits-to-elucidate-antibody-populations-elicit ed-by-a-recombinant-subunit-ebola-virus-vaccine-by-aquena-ball-phd-candida te SUMMARY:TRMD 690 Seminar: "Utilizing defined structural subunits to elucida te antibody populations elicited by a recombinant subunit Ebola virus vacc ine" by Aquena Ball\, PhD Candidate DESCRIPTION: \;\n \;\nDepartment of Tropical Medicine\, \nMedical M icrobiology and Pharmacology\n \;\nSeminar\nTRMD 690\n \;\nUtilizi ng defined structural subunits to elucidate antibody populations elicited by a recombinant subunit Ebola virus vaccine\nAquena Ball\nPh.D. Candidate \nWednesday\nApril 29\, 2020 @ 12:00-1:00 PM HST\nZoom Details:\nMeeting I D: 958 6947 0154\nFor password\, contact sambridh@hawaii.edu\n \;\nFor further information\, contact Dr. Vivek R. Nerurkar (phone: 692-1668\; em ail: nerurukar@hawaii.edu)\nSeminar Schedule @ http://manoa.hawaii.edu/tro picalmedicine/?page_id=4667\n \; CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:268@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200424T130000 DTEND;TZID=Pacific/Honolulu:20200424T140000 DTSTAMP:20200407T000709Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-for-taylor-tashirocomparison-of-antibody-responses-in-mice- generated-by-different-multivalent-filovirus-vaccines-based-on-recombinant -glycoprotein-subunits SUMMARY:Tropical Medicine MS Thesis Defense for Taylor Tashiro:"Comparison of Antibody Responses in Mice Generated by Different Multivalent Filovirus Vaccines Based on Recombinant Glycoprotein Subunits" DESCRIPTION: END:VEVENT BEGIN:VEVENT UID:264@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200423T140000 DTEND;TZID=Pacific/Honolulu:20200423T150000 DTSTAMP:20200321T023201Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ms-thesis-defense-for -louie-mar-gangcuangcocomparison-of-plasma-fibrotic-markers-in-people-livi ng-with-hiv-from-hawaii-and-the-philippines SUMMARY:UPDATED: MS Thesis Defense for Louie Mar Gangcuangco:"Comparison of plasma fibrotic markers in people living with HIV from Hawaii and the Phi lippines" DESCRIPTION:This defense has been rescheduled as an online Zoom videoconfer ence:\nJoin Zoom Meeting\nhttps://zoom.us/j/451149300Meeting ID: 451 149 3 00.\nDefense Seminar Announcement Louie Mar Gangcuangco\n\n LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:270@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200422T120000 DTEND;TZID=Pacific/Honolulu:20200422T130000 DTSTAMP:20200417T220524Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-upta ke-and-activation-profile-of-murine-dendritic-cells-in-response-to-stimula tion-with-functionalized-iron-oxide-nanoparticles-aneesa-golshan-phd-stude nt SUMMARY:TRMD 690 Seminar: "Uptake and activation profile of murine dendriti c cells in response to stimulation with functionalized iron oxide nanopart icles"\, Aneesa Golshan\, PhD Student DESCRIPTION:\ndiv {width: 400 px\;border: 10 px black\;padding: 50 px\;m argin: 20 px\;} \n\nDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology\n \;\n \;\nSEMINAR\nTRMD 690\n \;\n\n \; \nUptake and activation profile of murine dendritic cells in response to s timulation with functionalized iron oxide nanoparticles\n \;\nAneesa G olshan\, PhD Student\n \;\nWednesday\nApril 22\, 2020 @ 12:00 – 1:00 PM HST\n \;\nZoom link:\nhttps://hawaii.zoom.us/j/94922630935\n \ ;\nMeeting ID: 949 2263 0935\nFor password\, contact sambridh@hawaii.edu\n  \;\nJohn A. Burns School of Medicine\n651 Ilalo Street\, Honolulu\, H awaii 96813\n\nFor further information\, contact Dr. Vivek Nerurkar (ph. 6 92-1668\; email: nerurkar@hawaii.edu)\nSeminar Schedule @ http://manoa.haw aii.edu/tropicalmedicine/?page_id=4667\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:262@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200418T080000 DTEND;TZID=Pacific/Honolulu:20200418T154500 DTSTAMP:20200318T212707Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=save-the-date-2020-ha waii-asm-spring-meeting SUMMARY:CANCELED: 2020 Hawaii ASM Spring Meeting DESCRIPTION:This event has been canceled due to the COVID-19 emergency.\nHI ASM Spring Meeting Flyer\n CATEGORIES:Meeting LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:269@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200415T120000 DTEND;TZID=Pacific/Honolulu:20200415T130000 DTSTAMP:20200411T022116Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarscyll o-inositol-and-other-brain-metabolites-in-relation-to-brain-atrophy-cognit ion-and-inflammatory-markers-in-hiv-by-awapuhi-lee-ms-candidate SUMMARY:TRMD 690 Seminar:"Scyllo-inositol and other brain metabolites in re lation to brain atrophy\, cognition and inflammatory markers in HIV" by Aw apuhi Lee\, MS Candidate DESCRIPTION: END:VEVENT BEGIN:VEVENT UID:267@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200408T120000 DTEND;TZID=Pacific/Honolulu:20200408T130000 DTSTAMP:20200403T012240Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-char acterization-of-serological-response-to-dengue-and-zika-viruses-in-pregnan t-women-during-the-zika-virus-outbreak-in-brazil-by-kaitlin-driesse-phd-ca ndidate SUMMARY:TRMD 690 Seminar: "Characterization of serological response to deng ue and Zika viruses in pregnant women during the Zika virus outbreak in Br azil" by Kaitlin Driesse\, PhD Candidate DESCRIPTION:Zoom Link: \; \;https://hawaii.zoom.us/j/855332907\n\nC all in: (669) 900-6833\n\nZoom ID: 855 332 907\n\n CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT UID:266@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200401T120000 DTEND;TZID=Pacific/Honolulu:20200401T130000 DTSTAMP:20200330T064949Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-and -cobre-joint-seminar-ervebo-ebola-zaire-vaccine-a-tale-of-innovation-and-c ollaboration-by-beth-ann-coller-phd-merck-research-laboratories SUMMARY:Tropical Medicine and COBRE Joint Seminar: "ERVEBO® - EBOLA ZAIRE Vaccine: A Tale of Innovation and Collaboration"\, by Beth-Ann Coller\, P hD\, Merck Research Laboratories DESCRIPTION:Zoom Link: https://hawaii.zoom.us/j/4234371004\n\nCall in: (669 ) 900-6833\n\nZoom ID: 423 437 1004\n\n\n\n\n\n \;\n\n\nBeth-Ann Colle r\, Ph.D.\n\nExecutive Director\, Global Clinical Development\n\nMerck Res earch Laboratories\n\nNorth Wales\, Pennsylvania\n\nEbola continues to cau se significant morbidity and mortality in regions of the world where the p rovision of healthcare and vaccine are difficult. The Merck vaccine is a l ive recombinant vesicular stomatitis virus (VSV) containing the Zaire Ebol a virus glycoprotein (GP) in place of the VSV GP (rVSVΔG-ZEBOV-GP). Its s afety\, efficacy\, or immunogenicity has been evaluated in 13 clinical tri als\, and the vaccine has been approved for use in humans by the European Medicines Agency\, United States Food and Drug Administration\, several Af rican countries\, and has been prequalified by the World Health Organizati on. More than 300\,000 people have received the vaccine to date. Safety\, immunogenicity\, and efficacy data from across the program will be discuss ed as well as the use of the vaccine in the context of outbreak response.& nbsp\;  \; \;\n\n\n END:VEVENT BEGIN:VEVENT UID:265@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200325T120000 DTEND;TZID=Pacific/Honolulu:20200325T130000 DTSTAMP:20200325T013510Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-covi d-19-the-crown-evolves-by-elaine-bello-md-pali-momi-medical-center SUMMARY:TRMD 690 Seminar: "COVID-19: The Crown Evolves"\, by Elaine Bello\, MD\, MS\, John A Burns School of Medicine DESCRIPTION:Seminar Announcement: Erlaine Bello\, MD\n\nZoom link: https:// zoom.us/j/952473373 \n\nMeeting ID: 952473373 \;\n END:VEVENT BEGIN:VEVENT UID:263@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200312T120000 DTEND;TZID=Pacific/Honolulu:20200312T140000 DTSTAMP:20200305T223302Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=phd-dissertation-defe nse-for-danielle-clementscombination-immunotherapeutic-strategies-in-htlv- 1-infection-opportunities-for-managing-htlv-1-associated-complications SUMMARY:PhD Dissertation Defense for Danielle Clements:"Combination Immunot herapeutic Strategies in HTLV-1 Infection: Opportunities for Managing HTLV -1-associated Complications" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:261@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200311T120000 DTEND;TZID=Pacific/Honolulu:20200311T130000 DTSTAMP:20200304T191223Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-role-of-anti viral-pathways-in-restricting-zika-virus-infection-in-sertoli-cells-boonya nudh-jiyarom-trmd-ms-student SUMMARY:TRMD 690 Seminar: "Role of antiviral pathways in restricting Zika v irus infection in Sertoli cells"\, Boonyanudh Jiyarom\, TRMD MS Student DESCRIPTION: TRMD 690 Boonya 031120 ADA CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:260@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200304T120000 DTEND;TZID=Pacific/Honolulu:20200304T130000 DTSTAMP:20200228T203801Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-enhancing-in fectious-disease-surveillance-systems-to-bring-visibility-of-sexual-and-ge nder-minority-populations-by-charlene-bumanglag-phd-tropical-medicine-assi stant-professor SUMMARY:TRMD 690: "Enhancing infectious disease surveillance systems to bri ng visibility of sexual and gender minority populations"\, by Charlene Bum anglag\, PhD\, Tropical Medicine Assistant Professor DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:259@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200226T120000 DTEND;TZID=Pacific/Honolulu:20200226T130000 DTSTAMP:20200225T033813Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-prod uction-and-activity-assessment-of-a-recombinant-type-1-interferon-michael- faundo-trmd-ms-student SUMMARY:TRMD 690 Seminar: "Production and activity assessment of a recombin ant type-1 interferon"\, Michael Faundo\, TRMD MS Student DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:258@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200219T000000 DTEND;TZID=Pacific/Honolulu:20200219T000000 DTSTAMP:20200214T184649Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-ecological-metacommunity-dynamics-of-the-mosquito-microbiome-an d-its-relevance-to-public-health-by-dr-matthew-medeiros-pbrc SUMMARY:COBRE & Tropical Medicine Seminar: "Ecological Metacommunity Dynami cs of the Mosquito Microbiome and its Relevance to Public Health"\, by Dr. Matthew Medeiros\, PBRC DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:257@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200212T120000 DTEND;TZID=Pacific/Honolulu:20200212T130000 DTSTAMP:20200206T202655Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-path ophysiology-of-cubozoan-envenomation-mechanisms-models-and-clinical-manage ment-by-dr-angel-yanagihara SUMMARY:TRMD 690 Seminar: "Pathophysiology of cubozoan envenomation: mechan isms\, models and clinical management" by Dr. Angel Yanagihara DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:256@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200205T120000 DTEND;TZID=Pacific/Honolulu:20200205T130000 DTSTAMP:20200205T190035Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-the- fastest-growing-hiv-epidemic-in-the-western-pacific-disparities-in-hiv-tre atment-and-prevention-in-the-philippines-by-louie-gangcuangco-trmd-ms-stud ent SUMMARY:TRMD 690 Seminar: "The fastest-growing HIV epidemic in the Western Pacific: Disparities in HIV treatment and prevention in the Philippines" b y Louie Gangcuangco\, TRMD MS Student DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:255@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200129T120000 DTEND;TZID=Pacific/Honolulu:20200129T130000 DTSTAMP:20200121T201145Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-by-dr-dennis-j-grabafrican-trypanosome-interactions-with-the-hu man-blood-barrier-beyond-the-current-paradigm SUMMARY:COBRE/Tropical Medicine Seminar by Dr. Dennis J. Grab:"African Tryp anosome Interactions with the Human Blood-Barrier: Beyond the Current Para digm" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:254@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200122T120000 DTEND;TZID=Pacific/Honolulu:20200122T130000 DTSTAMP:20200116T020250Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminardevel oping-serological-tests-to-distinguish-flavivirus-infections-and-implicati ons-by-dr-wei-kung-wang SUMMARY:TRMD 690 Seminar:"Developing serological tests to distinguish flavi virus infections and implications"\, by Dr. Wei-Kung Wang DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:253@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20200115T120000 DTEND;TZID=Pacific/Honolulu:20200115T130000 DTSTAMP:20200114T195239Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-newl y-emerging-sexually-transmissible-viruses-testicular-defense-system-and-cl inical-implications-by-dr-saguna-verma SUMMARY:TRMD 690 Seminar: "Newly Emerging Sexually Transmissible Viruses: T esticular Defense System and Clinical Implications" by Dr. Saguna Verma DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:252@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191219T110000 DTEND;TZID=Pacific/Honolulu:20191219T120000 DTSTAMP:20191214T073806Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -dissertation-defense-for-danielle-clementscombination-immunotherapeutic-s trategies-in-htlv-1-infection-opportunities-for-managing-htlv-1-associated -complications SUMMARY:Tropical Medicine PhD Dissertation Defense for Danielle Clements: ”Combination Immunotherapeutic Strategies in HTLV-1 Infection: Opportuni ties for Managing HTLV-1-associated Complications” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:251@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191211T120000 DTEND;TZID=Pacific/Honolulu:20191211T130000 DTSTAMP:20191211T040702Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-elev ated-levels-of-pentraxin-3-correlate-with-neutrophil-counts-and-inflammato ry-markers-during-acute-kawasaki-disease-as-a-predictor-of-coronary-artery -lesions-by-lauren-ching SUMMARY:TRMD 690 Seminar: "Elevated levels of pentraxin 3 correlate with ne utrophil counts and inflammatory markers during acute Kawasaki disease\, a s a predictor of coronary artery lesions" by Lauren Ching\, TRMD PhD Stude nt DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:250@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191204T120000 DTEND;TZID=Pacific/Honolulu:20191204T130000 DTSTAMP:20191204T023443Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-inse ct-cell-expressed-recombinant-viral-glycoproteins-are-effective-immunogens -by-albert-to SUMMARY:TRMD 690 Seminar: "Insect Cell-Expressed Recombinant Viral Glycopro teins are Effective Immunogens" by Albert To DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:249@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191127T133000 DTEND;TZID=Pacific/Honolulu:20191127T143000 DTSTAMP:20191126T004211Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=brooks-mitchell-phd-d efense-understanding-the-myeloid-hiv-reservoir-in-hiv-associated-neurologi cal-disorder-during-antiretroviral-treated-hiv-infection SUMMARY:Brooks Mitchell PhD Defense: "Understanding the Myeloid HIV Reservo ir in HIV-Associated Neurological Disorder During Antiretroviral-treated H IV Infection" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:248@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191127T120000 DTEND;TZID=Pacific/Honolulu:20191127T130000 DTSTAMP:20191125T192228Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-unde rstanding-immune-mechanisms-of-hiv-associated-complications-ms-thesis-defe nse-for-scott-bowler SUMMARY:TRMD 690 Seminar: "Understanding immune mechanisms of HIV-associate d complications"\, MS Thesis Defense for Scott Bowler DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:247@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191120T120000 DTEND;TZID=Pacific/Honolulu:20191120T130000 DTSTAMP:20191119T193935Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-emer ging-challenges-of-aging-with-hiv-infection-in-the-era-of-antiretroviral-t herapy-role-of-glycan-binding-immunomodulatory-proteins-by-thomas-premeaux -tropical-medicine-phd-s SUMMARY:TRMD 690 Seminar: "Emerging Challenges of Aging with HIV Infection in the Era of Antiretroviral Therapy: Role of Glycan-binding Immunomodulat ory Proteins" by Thomas Premeaux\, Tropical Medicine PhD Student DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:246@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191113T120000 DTEND;TZID=Pacific/Honolulu:20191113T130000 DTSTAMP:20191112T191339Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-char acterizing-humoral-responses-to-novel-filovirus-vaccines-by-caitlin-willia ms SUMMARY:TRMD 690 Seminar: "Characterizing Humoral Responses to Novel Filovi rus Vaccines" by Caitlin Williams DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:245@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191106T120000 DTEND;TZID=Pacific/Honolulu:20191106T130000 DTSTAMP:20191106T202453Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-neur oangiostrongyliasis-rat-lungworm-disease-in-hawaii-developing-clinical-gui delines SUMMARY:TRMD 690 Seminar: Neuroangiostrongyliasis (Rat Lungworm Disease) in Hawaii: Developing Clinical Guidelines" DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:244@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191030T140000 DTEND;TZID=Pacific/Honolulu:20191030T150000 DTSTAMP:20191025T190232Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=webinar-ebolavirus-di scovery-in-west-africa-tracey-goldstein-phd-uc-davis SUMMARY:Webinar: "Ebolavirus Discovery in West Africa"\, Tracey Goldstein\, PhD\, UC Davis DESCRIPTION: END:VEVENT BEGIN:VEVENT UID:237@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191030T120000 DTEND;TZID=Pacific/Honolulu:20191030T130000 DTSTAMP:20190919T211053Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pceid-trmd-690-semina r-hiv-infection-of-the-brain-and-targeted-therapeutic-strategies-upal-roy- phd-university-of-texas-rio-grande-valley SUMMARY:PCEID & TRMD 690 Seminar: "HIV Infection of the Brain and Targeted Therapeutic Strategies"\, Upal Roy\, PhD\, University of Texas Rio Grande Valley DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:239@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191030T100000 DTEND;TZID=Pacific/Honolulu:20191030T110000 DTSTAMP:20190926T015511Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=guest-speaker-dr-sudh a-krishnamurthy-gladstone-institutes-postdoctoral-training-opportunities SUMMARY:Guest Speaker Dr. Sudha Krishnamurthy: "Gladstone Institutes Postdo ctoral Training Opportunities" DESCRIPTION:\n\n CATEGORIES:Informational Meeting LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:243@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191023T120000 DTEND;TZID=Pacific/Honolulu:20191023T130000 DTSTAMP:20191018T010714Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-the- role-of-autophagy-in-hiv-associated-cardiovascular-disease-by-ms-student-l ouie-mar-gangcuangco-md SUMMARY:TRMD 690 Seminar: "The Role of Autophagy in HIV-associated Cardiova scular Disease" by MS student Louie Mar Gangcuangco\, MD DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:242@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191016T120000 DTEND;TZID=Pacific/Honolulu:20191016T130000 DTSTAMP:20191016T005425Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-engi neered-exosomes-a-novel-zika-virus-vaccine-candidate-by-thomas-ken-awamura -ms-student SUMMARY:TRMD 690 Seminar: "Engineered Exosomes: A Novel Zika Virus Vaccine Candidate" by Thomas Ken Awamura\, MS Student DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:236@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191012T180000 DTEND;TZID=Pacific/Honolulu:20191012T210000 DTSTAMP:20190917T020752Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hi-asm-speaker-bettin a-fries-md-the-epidemiology-of-multi-drug-resistant-klebsiella-and-other-e nterobacteriaceae-in-the-u-s SUMMARY:HI-ASM Speaker Bettina Fries\, MD: "The epidemiology of multi drug resistant Klebsiella and other Enterobacteriaceae in the U.S." DESCRIPTION: HIASM_FALL2019_NEWSLETTER LOCATION:Pagoda Floating Restaurant\, 1525 Rycroft St.\, Honolulu\, HI\, 96 814\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1525 Rycroft St.\, Honolulu \, HI\, 96814\, United States;X-APPLE-RADIUS=100;X-TITLE=Pagoda Floating R estaurant:geo:0,0 END:VEVENT BEGIN:VEVENT UID:241@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191009T120000 DTEND;TZID=Pacific/Honolulu:20191009T130000 DTSTAMP:20191007T233123Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-comp arison-of-antibody-responses-in-mice-generated-by-different-multivalent-fi lovirus-vaccines-based-on-recombinant-gp-subunits-by-ms-student-taylor-tas hiro SUMMARY:TRMD 690 Seminar: "Comparison of antibody responses in mice generat ed by different multivalent Filovirus vaccines based on recombinant glycop rotein (GP) subunits" by MS Student Taylor Tashiro DESCRIPTION:ABSTRACT\n\nThe spread of Ebola virus is accelerating in the De mocratic Republic of Congo (DRC) and the number of deaths has been rapidly increasing and is now the world’s second largest Ebola outbreak with mo re than 2000 deaths and 3000 confirmed infections since the start of the o utbreak (WHO 2019). This is due to the virus’s ability to spread easily through contact with infected bodily fluids. Infected patients suffer a ra nge of symptoms which could lead to the development of Ebola Virus Disease \, leading to an untimely death. Generating an efficacious\, thermostable\ , multivalent vaccine against this virus and other filoviruses is necessar y for the protection of the population from the current outbreak\, possibl e future outbreaks\, and to prevent further spread of the disease. Pre-cli nical studies are currently in process for a thermostable\, multivalent re combinant subunit vaccine to evaluate if the antibodies produced in respon se to the vaccine elicit balanced antibody and neutralizing titers. \n CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:240@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20191002T120000 DTEND;TZID=Pacific/Honolulu:20191002T130000 DTSTAMP:20190930T201414Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-by-d r-chih-yun-lai-recombinant-subunit-ebola-virus-vaccines-induce-t-follicula r-helper-cell-and-neutralizing-antibody-responses SUMMARY:TRMD 690 Seminar by Dr. Chih-Yun Lai: "Recombinant Subunit Ebola Vi rus Vaccines Induce T Follicular Helper Cell and Neutralizing Antibody Res ponses" DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:238@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190925T120000 DTEND;TZID=Pacific/Honolulu:20190925T130000 DTSTAMP:20190925T191330Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-reco mbinant-protein-vaccines-protect-non-human-primates-from-ebola-sudan-and-m arburg-viruses-by-eleanore-chuang-phd SUMMARY:TRMD 690 Seminar: "Recombinant Protein Vaccines Protect Non-Human P rimates from Ebola\, Sudan\, and Marburg Viruses" by Eleanore Chuang\, PhD DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:235@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190918T120000 DTEND;TZID=Pacific/Honolulu:20190918T130000 DTSTAMP:20190917T004839Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-inve stigational-lectin-based-immunotherapy-by-dr-tsuyoshi-fujita SUMMARY:TRMD 690 Seminar: "Investigational Lectin-Based Immunotherapy" by D r. Tsuyoshi Fujita DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:234@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190913T110000 DTEND;TZID=Pacific/Honolulu:20190913T120000 DTSTAMP:20190912T021638Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=sii-career-developmen t-seminar-science-communication-dennis-f-mangan-phd-chalk-talk-science-dir ector-science-communication SUMMARY:SII Career Development Seminar: "Science Communication"\, Dennis F. Mangan\, PhD\, Chalk Talk Science Director DESCRIPTION: LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:233@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190911T120000 DTEND;TZID=Pacific/Honolulu:20190911T130000 DTSTAMP:20190906T195907Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pceidr-tropical-medic ine-seminar-global-health-security-in-the-pacific-century-gregg-m-nakano-m ald SUMMARY:PCEIDR/Tropical Medicine Seminar: "Global Health Security in the Pa cific Century"\, Gregg M. Nakano\, MALD DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:232@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190904T120000 DTEND;TZID=Pacific/Honolulu:20190904T130000 DTSTAMP:20190831T004523Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-dr-p akieli-kaufusi-presents-antigen-loaded-exosomes-as-therapeutic-vaccine-for -flavivirus-infection SUMMARY:TRMD Seminar: Dr. Pakieli Kaufusi presents "Antigen-Loaded Exosomes as Therapeutic Vaccine for Flavivirus Infection" DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:229@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190829T110000 DTEND;TZID=Pacific/Honolulu:20190829T120000 DTSTAMP:20190826T210017Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -dissertation-defense-for-liana-medina-the-immune-response-to-recombinant- subunit-vaccines SUMMARY:Tropical Medicine PhD Dissertation Defense for Liana Medina: "The i mmune response to recombinant subunit vaccines" DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:230@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190828T120000 DTEND;TZID=Pacific/Honolulu:20190828T130000 DTSTAMP:20190828T080544Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-edward- p-desmond-dna-sequencing-to-determine-mycobacterium-tuberculosis-drug-sens itivity SUMMARY:Seminar by Dr. Edward P. Desmond: “DNA Sequencing to Determine My cobacterium Tuberculosis Drug Sensitivity” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:231@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190828T090000 DTEND;TZID=Pacific/Honolulu:20190828T100000 DTSTAMP:20190828T080923Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-esther- ellis-dr-brett-ellis-us-virgin-islands-public-health-infectious-disease-hu rricane-recovery SUMMARY:Seminar by Dr. Esther Ellis & Dr. Brett Ellis: “US Virgin Islands Public Health Infectious Disease & Hurricane Recovery” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:228@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190820T140000 DTEND;TZID=Pacific/Honolulu:20190820T150000 DTSTAMP:20190810T021005Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-inf ectious-disease-alicata-award-presentation SUMMARY:Tropical Medicine & Infectious Disease Alicata Award Presentation DESCRIPTION: LOCATION:JABSOM BioScience Bldg. Rm 320\, 651 Ilalo St.\, Honolulu\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm 320:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:227@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190801T080000 DTEND;TZID=Pacific/Honolulu:20190801T090000 DTSTAMP:20190730T203750Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pediatric-grand-round s-by-marian-melish-md-eosinophilic-meningitis-in-children-in-hawaii SUMMARY:Pediatric Grand Rounds by Marian Melish\, MD: "Eosinophilic Meningi tis in Children in Hawai‘i" DESCRIPTION:WEBINAR WILL BE BROADCASTED IN BSB 320N LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:226@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190726T110000 DTEND;TZID=Pacific/Honolulu:20190726T120000 DTSTAMP:20190722T204712Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=special-lecture-caree r-opportunities-for-phds-by-dr-robert-rivers-niddk-nih SUMMARY:Special Lecture: "Career Opportunities for PhDs" by Dr. Robert Rive rs\, NIDDK/NIH DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:225@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190716T090000 DTEND;TZID=Pacific/Honolulu:20190716T100000 DTSTAMP:20190705T194737Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=consortium-of-univers ities-for-global-health-webinar-vaccine-vaccine-hesitancy SUMMARY:Consortium of Universities for Global Health Webinar: "Vaccines & V accine Hesitancy" DESCRIPTION:\n\nVaccines have been a vital asset in reducing childhood mort ality and morbidity. They have saved millions of children’s lives around the world and are one of the most cost effective public health measures.\ n\nDespite overwhelming evidence to the life-saving properties of vaccines there has been an increase in vaccine hesitancy in many parts of the worl d. This has resulted in a deadly resurgence of preventable infectious dise ases that is claiming an increasing number of children’s lives.\n\nJoin us on Tuesday\, July 16 at 3pm ET for a webinar by two global leaders in t he field of vaccines and vaccine hesitancy to learn about this challenge a nd what we can do to enable children to access the vaccines they need to p rotect them from an array of preventable and potentially lethal diseases.\ n\nSPEAKERS:\n\n Dina Borzekowski\, Ed.D\, Ed.M\, Research Professor\, Be havioral and Community Health\; Interim Director\, The Global Health Initi ative\, University of Maryland\n\nDina L.G. Borzekowski is the interim Dir ector of the Global Health Initiative and a Research Professor at the Univ ersity of Maryland’s School of Public Health. Her educational degrees ar e from Cornell University (B.S.\, Biology)\, Columbia University (M.S.\, C ommunication\, Computing and Technology)\, and Harvard University (Ed.M.\, Educational Media\; Ed.D.\, Developmental Psychology).\n\nBorzekowski’s topics of expertise include: Health Communication\, Global Health\, Mater nal and Child Health\, Adolescent Health\, and Research Methods. Borzekows ki has over 70 papers and chapters in peer-reviewed journals and anthologi es.\n\nIn her professional career\, Borzekowski’s has focused on childre n\, media and health. She has conducted research in around 32 countries ex ploring how young people use media and how media impacts on the health and development of children and adolescents. Additionally\, Borzekowski has h ad experience producing and evaluating media\, including work with Sesame Workshop\, MTV\, and Ubongo Kids. She has recently introduced the term “ constancy” to describe the constant state of media in children’s lives .\n\n Peter Hotez\, MD\, PhD\, Dean\, National School of Tropical Medicin e\, Professor\, Pediatrics and Molecular &\; Virology and Microbiology\ , Co-Head\, Section of Pediatric Tropical Medicine\, Baylor College of Med icine\n\nPeter J. Hotez\, M.D.\, Ph.D. is Dean of the National School of T ropical Medicine and Professor of Pediatrics and Molecular Virology &\; Microbiology at Baylor College of Medicine where he is also the Co-Direct or of the Texas Children’s Center for Vaccine Development (CVD). He is a n internationally-recognized physician-scientist in neglected tropical dis eases vaccine development. Dr. Hotez obtained his undergraduate degree in molecular biophysics from Yale University in 1980\, followed by a Ph.D. de gree in biochemistry from Rockefeller University in 1986\, and an M.D. fro m Weil Cornell Medical College in 1987. Dr. Hotez has authored more than 5 00 original papers and is the author of 3 single-author books\, most recen tly Vaccines Did Not cause Rachel’s Autism (Johns Hopkins University Pre ss). Dr. Hotez was President of the American Society of Tropical Medicine and Hygiene and he is founding Editor-in-Chief of PLoS Neglected Tropical Diseases. He is an elected member of the National Academy of Medicine and the American Academy of Arts &\; Sciences. In 2011 he was awarded the A braham Horwitz Award by the Pan American Health Organization of the WHO. I n 2014-16 he served in the Obama Administration as US Envoy\, focusing on vaccine diplomacy initiatives between the US Government and countries in t he Middle East and North Africa. In 2018 he was appointed to serve on the Board of Governors for the US Israel Binational Science Foundation. He has served on infectious disease task forces for two consecutive Texas Govern ors. For these efforts in 2017 he was named by FORTUNE Magazine as one of the 34 most influential people in health care\, and in 2018 he received th e Sustained Leadership Award from Research!America.\n\nClick for more info rmation \; LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:224@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190703T120000 DTEND;TZID=Pacific/Honolulu:20190703T130000 DTSTAMP:20190703T204052Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=jourdan-posner-phd-di ssertation-defense-seminar-defining-molecular-adjuvant-effects-on-human-b- cell-subsets SUMMARY:Jourdan Posner PhD Dissertation Defense Seminar: "Defining molecula r adjuvant effects on human B cell subsets." DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:223@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190606T100000 DTEND;TZID=Pacific/Honolulu:20190606T110000 DTSTAMP:20190604T221824Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=flow-cytometry-semina r-flow-cytometry-and-cell-sorting-for-every-type-of-biological-samples SUMMARY:Flow Cytometry Seminar: Flow Cytometry and Cell Sorting for Every T ype of Biological Samples DESCRIPTION: LOCATION:Hawaii Institute of Geophysics\, Rm. 131\, 2525 Correa Rd.\, Honol ulu\, HI\, 96822\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=2525 Correa Rd.\, Honolulu\ , HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=Hawaii Institute o f Geophysics\, Rm. 131:geo:0,0 END:VEVENT BEGIN:VEVENT UID:222@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190516T120000 DTEND;TZID=Pacific/Honolulu:20190516T130000 DTSTAMP:20190513T175805Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-center-for-aid s-seminar-brain-health-in-the-setting-of-hiv-lessons-from-the-acute-hiv-an d-the-ucsf-elders-study-victor-valcour-md-phd-uc-san-francisco SUMMARY:Hawaii Center for AIDS Seminar: "Brain Health in the setting of HIV : Lessons from the Acute HIV and the UCSF Elders Study"\, Victor Valcour\, MD\, PhD\, UC San Francisco DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:221@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190507T143000 DTEND;TZID=Pacific/Honolulu:20190507T153000 DTSTAMP:20200427T214143Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-seminar-vaccine s-for-infectious-diseases-at-the-walter-reed-army-institute-of-research-ai ds-to-zika-by-dr-nelson-michael-center-for-infectious-disease-research-wra ir SUMMARY:COBRE Seminar: "Vaccines for Infectious Diseases at the Walter Reed Army Institute of Research: AIDS to Zika" by Dr. Nelson Michael\, Center for Infectious Disease Research\, WRAIR DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:220@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190501T120000 DTEND;TZID=Pacific/Honolulu:20190501T130000 DTSTAMP:20190429T183730Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminarimmun omodulatory-effects-of-iron-oxide-nanoparticles-a-self-adjuvanted-vaccine- delivery-platform-by-tropical-medicine-phd-student-aneesa-golshan SUMMARY:TRMD 690 Seminar:"Immunomodulatory effects of iron oxide nanopartic les\, a self-adjuvanted vaccine delivery platform" by Tropical Medicine Ph D Student Aneesa Golshan DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:212@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu;VALUE=DATE:20190425 DTEND;TZID=Pacific/Honolulu;VALUE=DATE:20190427 DTSTAMP:20190312T015934Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=annual-biomedical-sci ences-and-health-disparities-symposium SUMMARY:JABSOM Annual Biomedical Sciences and Health Disparities Symposium DESCRIPTION:Sponsored by John A. Burns School of Medicine\, University of H awai‘i at Manoa\nRMATRIX\nOla HAWAII\nINBRE IV\n \;\nPresented by\nT he Department of Cell and Molecular Biology\nFor questions\, contact Lyn H amamura @ 692-1514 or lynh@hawaii.edu\n \; CATEGORIES:Research Symposium LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:219@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190424T120000 DTEND;TZID=Pacific/Honolulu:20190424T130000 DTSTAMP:20190419T030940Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-deng ue-immunity-and-zika-virus-infection-by-kaitlin-driesse-tropical-medicine- phd-student SUMMARY:TRMD 690 Seminar: "Dengue Immunity and Zika Virus Infection" by Kai tlin Driesse\, Tropical Medicine PhD Student DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:218@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190417T120000 DTEND;TZID=Pacific/Honolulu:20190417T130000 DTSTAMP:20190415T200056Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-corr elates-of-protection-in-non-human-primates-receiving-a-recombinant-subunit -based-ebola-virus-vaccine-by-liana-medina-tropical-medicine-phd-student SUMMARY:TRMD 690 Seminar: "Correlates of Protection in Non-human Primates R eceiving a Recombinant\, Subunit-based Ebola Virus Vaccine" by Liana Medin a\, Tropical Medicine PhD Student DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:215@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190413T083000 DTEND;TZID=Pacific/Honolulu:20190413T151500 DTSTAMP:20190403T005123Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2019-hi-asm-spring-me eting-featuring-dr-timothy-endy-dengue-a-global-health-problem-perspective s-from-20-years-of-prospective-studies SUMMARY:2019 HI-ASM Spring Meeting featuring Dr. Timothy Endy: "Dengue - a global health problem: perspectives from 20 years of prospective studies" DESCRIPTION: CATEGORIES:Conference LOCATION:Ka'ikena Dining Room\, Kapiolani Community College\, 4303 Diamond Head Road\, Honolulu\, HI\, 96816\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=4303 Diamond Head Road\, Ho nolulu\, HI\, 96816\, United States;X-APPLE-RADIUS=100;X-TITLE=Ka'ikena Di ning Room\, Kapiolani Community College:geo:0,0 END:VEVENT BEGIN:VEVENT UID:216@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190410T120000 DTEND;TZID=Pacific/Honolulu:20190410T130000 DTSTAMP:20190404T195009Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-ceni criviroc-reduces-system-fibrotic-markers-in-hiv-art-adults-by-scott-bowler -tropical-medicine-ms-student SUMMARY:TRMD 690 Seminar: "Cenicriviroc reduces system fibrotic markers in HIV/ART adults" by Scott Bowler\, Tropical Medicine MS Student DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:217@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190408T120000 DTEND;TZID=Pacific/Honolulu:20190408T130000 DTSTAMP:20190404T235508Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-by-dr-carlos-brites-federal-university-of-bahia-brazil-endemic- and-epidemic-infectious-diseases-in-brazil SUMMARY:COBRE/Tropical Medicine Seminar by Dr. Carlos Brites\, Federal Univ ersity of Bahia\, Brazil: "Endemic and Epidemic Infectious Diseases in Bra zil" DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:214@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190403T120000 DTEND;TZID=Pacific/Honolulu:20190403T130000 DTSTAMP:20190401T190513Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-dual -role-of-axl-receptor-in-zika-virus-infection-of-human-testicular-cells-by -daniel-p-strange-tropical-medicine-phd-student SUMMARY:TRMD 690 Seminar: "Dual role of Axl receptor in Zika virus infectio n of human testicular cells" by Daniel P. Strange\, Tropical Medicine PhD Student DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:213@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190327T120000 DTEND;TZID=Pacific/Honolulu:20190327T130000 DTSTAMP:20190322T014157Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=michellei-fisher-ms-t hesis-defense-histone-deacetylase-inhibitors-modulate-human-polyomavirus-j c-replication SUMMARY:Michellei Fisher MS Thesis Defense: "Histone deacetylase inhibitors modulate human polyomavirus JC replication" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:210@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190320T090000 DTEND;TZID=Pacific/Honolulu:20190320T113000 DTSTAMP:20190311T205626Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2019-cobre-mini-sympo sium SUMMARY:2019 COBRE Mini-Symposium DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:211@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190313T120000 DTEND;TZID=Pacific/Honolulu:20190313T130000 DTSTAMP:20190312T014102Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-test icular-macrophages-what-are-they-doing-in-the-testes-by-boonyanudh-jiyarom SUMMARY:TRMD 690 Seminar: "Testicular Macrophages: What Are They Doing in t he Testes?"\, by Boonyanudh Jiyarom DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:209@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190306T120000 DTEND;TZID=Pacific/Honolulu:20190306T130000 DTSTAMP:20190304T200349Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-dete rmining-the-role-of-mris-in-early-detection-of-neuroangiostrongyliasis-by- chelsea-a-nichols SUMMARY:TRMD 690 Seminar: "Determining the Role of MRI's in Early Detectio n of Neuroangiostrongyliasis" by Chelsea A. Nichols DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:208@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190228T100000 DTEND;TZID=Pacific/Honolulu:20190228T110000 DTSTAMP:20190225T205606Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=mci-core-themofisher- scientific-flow-cytometry-seminar-approaches-for-microbial-and-small-parti cle-analysis-using-flow-cytometry SUMMARY:MCI Core & ThemoFisher Scientific Flow Cytometry Seminar: "Approach es for Microbial and Small Particle Analysis using Flow Cytometry" DESCRIPTION: LOCATION:Hawaii Institute of Geophysics\, Rm. 131\, 2525 Correa Rd.\, Honol ulu\, HI\, 96822\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=2525 Correa Rd.\, Honolulu\ , HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=Hawaii Institute o f Geophysics\, Rm. 131:geo:0,0 END:VEVENT BEGIN:VEVENT UID:183@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu;VALUE=DATE:20190228 DTEND;TZID=Pacific/Honolulu;VALUE=DATE:20190305 DTSTAMP:20180907T021308Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=maui-cancer-immunothe rapy-conference-t-cell-based-immunotherapy-a-deeper-dive-iii SUMMARY:Maui Cancer Immunotherapy Conference: "T Cell Based Immunotherapy: A Deeper Dive III" DESCRIPTION:REMINDER: Additional 20% discount available if you register bef ore Nov. 1st.  \;Contacts: Ryan Montler (ryan.montler@agonox.com) & \; Joe Ramos (joeramos@hawaii.edu)\n\nDiscount code: Providence\n\nPasswor d: 2019EACRI20pct\n\n LOCATION:Fairmont Kea Lani\, 4100 Wailea Alanui Drive\, Wailea\, HI\, Unite d States GEO:20.6754793;-156.441688 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=4100 Wailea Alanui Drive\, Wailea\, HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Fairmont Kea Lani:g eo:20.6754793,-156.441688 END:VEVENT BEGIN:VEVENT UID:207@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190227T150000 DTEND;TZID=Pacific/Honolulu:20190227T160000 DTSTAMP:20190225T204744Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=mci-and-ccmif-cores-f low-cytometry-seminar-extracellular-vesicle-and-small-particle-analysis-us ing-flow-cytometry SUMMARY:MCI and CCMIF Cores Flow Cytometry Seminar: "Extracellular Vesicle and Small Particle Analysis Using Flow Cytometry" DESCRIPTION: LOCATION:UH Cancer Center\, Rm. 401\, 651 Ilalo St.\, Honolulu\, HI\, 96813 \, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=UH Cancer Center\, R m. 401:geo:0,0 END:VEVENT BEGIN:VEVENT UID:206@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190227T120000 DTEND;TZID=Pacific/Honolulu:20190227T130000 DTSTAMP:20190226T190340Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-vide o-presentation-by-dr-pardis-sabeti-harvard-university-on-genomic-surveilla nce-and-response-system-for-infectious-disease-outbreaks SUMMARY:TRMD 690 Seminar: Video Presentation by Dr. Pardis Sabeti\, Harvard University on "Genomic Surveillance and Response System for Infectious Di sease Outbreaks" DESCRIPTION:\nNational Academy of Sciences\nPardis Christine Sabeti\, recip ient of the 2017 Richard Lounsbery Award presented the Lounsbery Lecture\, "Genomic Surveillance and Response System for Infectious Disease Outbreak s" at the University Massachusetts\, Boston on Nov. 7\, 2018.\n\nLong befo re Ebola erupted into a full-blown outbreak\, it spread undetected. The co nsequences were devastating\, yet the next pandemic—Zika—was already c irculating under the radar. Oversights like this occur surprisingly often even in the best U.S. hospitals\, where most infectious diseases are not p roperly diagnosed or tracked until it is too late. Health workers on the g round—nurses\, doctors and public health agencies—don’t have the too ls and information they need\, when they need them most. To defeat outbrea ks and save lives\, the world needs diagnostic tools and integrated inform ation systems that can detect infectious threats and track their spread. W atch to learn the 5 steps Sabeti says we must take to improve our systems and track the spread of outbreaks. LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:205@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190220T120000 DTEND;TZID=Pacific/Honolulu:20190220T130000 DTSTAMP:20190220T081022Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-effe cts-of-a-trivalent-filovirus-vaccine-in-a-murine-model-by-trmd-ms-student- aquena-ball SUMMARY:TRMD 690 Seminar: “Effects of a Trivalent Filovirus Vaccine in a Murine Model”\, by TRMD MS Student Aquena Ball DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:204@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190215T090000 DTEND;TZID=Pacific/Honolulu:20190215T120000 DTSTAMP:20190208T220640Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=jabsom-bioinformatics -core-workshop-on-genome-assembly-evaluation-and-visualization SUMMARY:JABSOM Bioinformatics Core Workshop on Genome Assembly\, Evaluation and Visualization DESCRIPTION: LOCATION:Jabsom MEB Computer Lab 107D\, 651 Ilalo St.\, Honolulu\, HI\, 968 13\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=Jabsom MEB Computer Lab 107D:geo:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:203@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190213T120000 DTEND;TZID=Pacific/Honolulu:20190213T130000 DTSTAMP:20190208T220015Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-the- gut-microbiome-and-anti-hiv-immune-responses-in-chronic-hiv-infection-by-i vo-n-sahbandar-md-phd SUMMARY:TRMD 690 Seminar: "The Gut Microbiome and Anti-HIV Immune Responses in Chronic HIV Infection" by Ivo N. SahBandar\, MD\, PhD DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:198@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190211T080000 DTEND;TZID=Pacific/Honolulu:20190211T170000 DTSTAMP:20190115T210023Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=medical-mycology-a-on e-day-workshop-basics-clinical-case-studies SUMMARY:Medical Mycology: A One-Day Workshop - Basics & Clinical Case Studi es DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:202@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190206T120000 DTEND;TZID=Pacific/Honolulu:20190206T130000 DTSTAMP:20190131T222846Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminart-cel l-exhaustion-and-mitochondrial-function-in-chronic-hiv-by-louie-mar-gangcu angco-tropical-medicine-ms-student SUMMARY:TRMD 690 Seminar:"T cell exhaustion and mitochondrial function in c hronic HIV" by Louie Mar Gangcuangco\, Tropical Medicine MS Student DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:200@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190201T110000 DTEND;TZID=Pacific/Honolulu:20190201T120000 DTSTAMP:20190125T011248Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-car eer-development-seminar-discussion-science-patents-perspectives-from-a-pat ent-lawyer-martin-chang-jd-mpa SUMMARY:Tropical Medicine Career Development Seminar & Discussion: "Science & Patents: Perspectives from a Patent Lawyer"\, Martin Chang\, JD\, MPA DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:201@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190130T120000 DTEND;TZID=Pacific/Honolulu:20190130T130000 DTSTAMP:20190124T202356Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-proposal-seminar-congenital-zika-syndrome-in-guinea-pigs-by-shannon -stone SUMMARY:Tropical Medicine MS Thesis Proposal Seminar: "Congenital Zika Synd rome in Guinea Pigs" by Shannon Stone DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:199@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190123T120000 DTEND;TZID=Pacific/Honolulu:20190123T130000 DTSTAMP:20190118T193538Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-phys iological-and-biomechanical-benefits-of-whole-body-vibration-exercise-for- elders-and-people-living-with-hiv-aids-dr-iris-kimura SUMMARY:TRMD 690 Seminar: "Physiological and biomechanical benefits of whol e body vibration - Exercise for elders and people living with HIV/AIDS"\, Dr. Iris Kimura DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:197@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20190109T120000 DTEND;TZID=Pacific/Honolulu:20190109T130000 DTSTAMP:20190105T001745Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-aptamers-chemical-antibodies-with-biomedical-potential-iain-macpherso n-phd-assistant-professor-tmmmp SUMMARY:Tropical Medicine Seminar: "Aptamers: Chemical antibodies with biom edical potential"\, Iain MacPherson\, PhD\, Assistant Professor\, TMMMP DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:196@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181212T113000 DTEND;TZID=Pacific/Honolulu:20181212T133000 DTSTAMP:20181210T202224Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-hol iday-party SUMMARY:Tropical Medicine Holiday Party DESCRIPTION:Tropical Medicine Christmas Potluck\n\n11:30 AM - 1:30 PM\, Wed nesday December 12\, 2018\n\nLocation: BSB 320\n\nPotluck signup sheet pos ted in department (door to coffee room)\n\nIf you prefer not to bring a po tluck item\, a $10 contribution may be made to Eileen Nakano or Teri Ann W ong\n\nGift exchange: bring a gift worth $15 to Eileen or Becky\n\n \; \n\n \; LOCATION:JABSOM BioScience Bldg. Rm 320\, 651 Ilalo St.\, Honolulu\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm 320:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:195@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181211T120000 DTEND;TZID=Pacific/Honolulu:20181211T130000 DTSTAMP:20181205T234039Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-center-for-aid s-dept-of-tropical-medicine-med-microbiology-pharmacology-seminar-ending-a -plague-how-compassion-humanism-and-medicine-will-end-the-aids-epidemic-by -ben-young-md SUMMARY:Hawaii Center for AIDS & Dept. of Tropical Medicine\, Med. Microbio logy & Pharmacology Seminar: "Ending a Plague: How Compassion\, Humanism\, and Medicine will End the AIDS Epidemic" by Ben Young\, MD\, PhD\, Senior Global Medical Director\, ViiV Healthcare DESCRIPTION:\n\n LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:194@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181206T120000 DTEND;TZID=Pacific/Honolulu:20181206T140000 DTSTAMP:20181203T214647Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=sii-career-developmen t-seminar-rebecca-kanenaka-aphl-microbiologist-foodborne-disease-surveilla nce-and-response-coordinator-hawaii-state-dept-of-health SUMMARY:SII Career Development Seminar: Rebecca Kanenaka\, APHL Microbiolog ist & Foodborne Disease Surveillance and Response Coordinator\, Hawaii Sta te Dept. of Health DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:193@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181121T120000 DTEND;TZID=Pacific/Honolulu:20181121T130000 DTSTAMP:20181121T000153Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-seminar-for-francine-f-azouz-role-of-schlafen4-in-west-nile-virus-p athogenesis SUMMARY:Tropical Medicine MS Thesis Seminar for Francine F. Azouz: "Role of Schlafen4 in West Nile Virus Pathogenesis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:192@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181107T120000 DTEND;TZID=Pacific/Honolulu:20181107T130000 DTSTAMP:20181106T001843Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-by-jourdan-posner-phd-candidate-the-marginal-zone-b-cell-controversy SUMMARY:Tropical Medicine Seminar by Jourdan Posner\, PhD Candidate: "The M arginal Zone B cell Controversy" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:191@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181031T120000 DTEND;TZID=Pacific/Honolulu:20181031T130000 DTSTAMP:20181029T192115Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-by-albert-to-tropical-medicine-phd-student-development-of-a-lassa-fev er-recombinant-subunit-vaccine SUMMARY:Tropical Medicine Seminar by Albert To\, Tropical Medicine PhD Stud ent: "Development of a Lassa Fever Recombinant Subunit Vaccine" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:190@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181025T110000 DTEND;TZID=Pacific/Honolulu:20181026T130000 DTSTAMP:20181024T074035Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=asuh-graduate-fair SUMMARY:ASUH Graduate Fair\, October 25 & 26\, 2018 DESCRIPTION: LOCATION:University of Hawaii at Manoa\, Campus Center Courtyard\, 2465 Cam pus Road\, Honolulu\, HI\, 96822\, United States GEO:21.2987829;-157.81906809999998 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=2465 Campus Road\, Honolulu \, HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=University of Haw aii at Manoa\, Campus Center Courtyard:geo:21.2987829,-157.81906809999998 END:VEVENT BEGIN:VEVENT UID:188@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181024T120000 DTEND;TZID=Pacific/Honolulu:20181024T130000 DTSTAMP:20181019T015752Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-how-sri-lanka-eliminated-malaria-by-dr-kevin-palmer-dept-of-tro pical-medicine-medical-microbiology-pharmacology SUMMARY:COBRE/Tropical Medicine Seminar: "How Sri Lanka Eliminated Malaria" by Dr. Kevin Palmer\, Dept. of Tropical Medicine\, Medical Microbiology & Pharmacology DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:189@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181022T120000 DTEND;TZID=Pacific/Honolulu:20181022T130000 DTSTAMP:20181022T192128Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cmb-seminar-by-philip -verhoef-md-phd-the-dysfunctional-host-response-in-sepsis-a-unique-role-fo r-type-2-immunity SUMMARY:CMB Seminar by Philip Verhoef\, MD\, PhD: The Dysfunctional Host Re sponse in Sepsis: A Unique Role for Type 2 Immunity? DESCRIPTION:Philip Verhoef\, MD\, PhD\n\nAssistant Professor\n\nThe Univers ity of Chicago\n\nDept. of Medicine\, Section of Pulmonary &\; Critical Care\n\nChicago\, IL\n\n \;\n\nGuest of Dr. Elizabeth Tam LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:186@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181017T120000 DTEND;TZID=Pacific/Honolulu:20181017T130000 DTSTAMP:20181013T192141Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-by-dr-gultekin-tamguney-peripheral-challenge-with-alpha-synucle in-fibrils-results-in-parkinsons-disease-like-signs-in-mice SUMMARY:COBRE/Tropical Medicine Seminar by Dr. Gultekin Tamguney: “Periph eral Challenge with Alpha-synuclein Fibrils Results in Parkinson’s Disea se-like Signs in Mice” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:187@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181015T120000 DTEND;TZID=Pacific/Honolulu:20181015T130000 DTSTAMP:20181013T192615Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-by-may-c-chu-ph-d-university-of-colorado-anschutz-medical-campu s-epidemic-and-outbreak-response-challenges-in-diagnosis-and-biosecurity SUMMARY:COBRE/Tropical Medicine Seminar by May C. Chu\, Ph.D.\, University of Colorado Anschutz Medical Campus: “Epidemic and Outbreak Response: Ch allenges in Diagnosis and Biosecurity” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:184@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181005T060000 DTEND;TZID=Pacific/Honolulu:20181005T103000 DTSTAMP:20180907T200446Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=nih-grant-writing-wor kshop-in-person-or-livestreaming SUMMARY:NIH Grant Writing Workshop - in person or livestreaming DESCRIPTION: \;\n\n \; LOCATION:Columbia University Medical Center\, 622 W 168th St\, New York\, N Y\, United States GEO:40.841311;-73.94067000000001 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=622 W 168th St\, New York\, NY\, United States;X-APPLE-RADIUS=100;X-TITLE=Columbia University Medical Center:geo:40.841311,-73.94067000000001 END:VEVENT BEGIN:VEVENT UID:185@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20181003T120000 DTEND;TZID=Pacific/Honolulu:20181003T130000 DTSTAMP:20180926T011609Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pceidr-cobre-seminar- infectious-disease-and-irreversible-catastrophic-risk-risk-management-in-c omplex-society-by-dr-james-campbell-professor-daniel-k-inouye-asia-pacific -center-for-security SUMMARY:PCEIDR COBRE Seminar: "Infectious Disease and Irreversible Catastro phic Risk: Risk Management in Complex Society" by Dr. James Campbell\, Pr ofessor\, Daniel K. Inouye Asia-Pacific Center for Security Studies DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:182@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180905T120000 DTEND;TZID=Pacific/Honolulu:20180905T130000 DTSTAMP:20180905T041750Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-diane-w allace-taylor-malaria-diagnosis-var2csa-and-antibody-avidity-malaria-resea rch-in-the-taylor-lab-past-present-and-future SUMMARY:Seminar by Dr. Diane Wallace Taylor: “Malaria: Diagnosis\, VAR2CS A and Antibody Avidity [Malaria Research in the Taylor Lab: Past\, Present and Future]” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:181@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180827T080000 DTEND;TZID=Pacific/Honolulu:20180827T170000 DTSTAMP:20180822T190605Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=yanagimachi-symposium SUMMARY:Yanagimachi Symposium DESCRIPTION:Yanagimachi 90th Birthday Symposium Program\n\n\n\n\nMonday\, A ugust 27\, 2018\nSullivan Center\, University of Hawaii Cancer Center\n\n8 :00 W. Steven Ward\, PhD\nDirector\, Institute for Biogenesis Research\n\n Welcome\n\n8:05 Mariana Gerschenson\, PhD\nAssociate Dean for Research\, J ohn A. Burns School of Medicine\n\nDavid Lasner\, PhD\n\nPresident\, Unive rsity of Hawaii\n\nMichael Bruno\, PhD\n\nVice Chancellor for Research\, U niversity of Hawaii at Manoa\n\n8:15 W. Steven Ward\, PhD\nDirector\, Inst itute for Biogenesis Research\n\n“Contributions of Dr. Yanagimachi to Sc ience and the University of Hawaii”\n\nSCIENTIFIC SESSION 1: Moderator\, Monika Ward\, PhD\n\n\n\n\n\n\n8:30\n\n\n\n\nProfessor\, Institute for Bi ogenesis Research\n\nMitinori Saitou\, MD\, PhD\n\nDistinguished Professor \, Research Institute for Microbial Diseases\, Osaka University\n\n“Mech anism and In Vitro Reconstitution of Human Germ Cell Development“\n\n\n\ n\n\n\n9:30 Yukiko Yamazaki\, Ph.D.\nAssociate Professor\, Institute for B iogenesis Research\n\n“Sex Differentiation of Fetal Germ Cells”\n\n9:4 5 Yusuke Marikawa\, Ph.D.\nAssociate Professor\, Institute for Biogenesis Research\n\n“Bodybuilding with Stem Cells: In Vitro Morphogenesis Model for Teratogen Research”\n\n10:00 Stacy Tsai\, MD\nAssistant Professor\, Division of Maternal Fetal Medicine\, Dept. Ob/Gyn\n\n“Effects of Matern al Diabetes on Pregnancy Outcomes”\n\n10:15 Coffee Break/Posters/Chantel l Balaan &\; Jon Riel hula/ukulele performance\n\nSCIENTIFIC SESSION 2: Moderator\, Yukiko Yamazaki PhD\n\nAssociate Professor\, Institute for Bi ogenesis Research\n\n10:45 Dolores Lamb\, PhD\nVice Chair\, Department of Urology (Research)\, Director of the Center for Reproductive Genomics\, Pr ofessor of Molecular Biology in Urology\, Weill Cornell Medical College\n\ n\n\n\n\n\n“Genetics and Genomic Basis of Human Male Infertility”\n\n\ n\n\n\n\n\n\n11:45\n\n\n\n\nAtsushi Tanaka\, MD\, PhD\n\nJuntendo Universi ty Hospital\, Japan\n\n“What Should We Do for the Improvement of ROSI? ”\n\nMonika Ward\, Ph.D.\n\nProfessor\, Institute for Biogenesis Researc h\n\n“Assisted Reproduction Rescue of Abnormal Spermiogenesis.”\n\nLun ch (provided)\n\n\n\n\n\n\n12:15\n\n12:30\n\n\n\n\n\n\nSCIENTIFIC SESSION 3: Moderator Johann Urschitz\, PhD\n\nAssistant Professor\, Institute for Biogenesis Research\n\n1:30 Masahito Ikawa\, PhD\nDistinguished Professor\ , Research Institute for Microbial Diseases\, Osaka University\n\n“CRISP R/Cas9 Mediated Genome Editing in Mice and Its Application for the Study o f Reproduction”\n\n2:30 Johann Urschitz\, Ph.D.\nAssistant Professor\, I nstitute for Biogenesis Research\n\n\n\n\n\n\n2:45\n\n\n\n\n“Non-Viral I n Vivo Gene Modulation in the Placenta”\n\nRich Allsopp\, Ph.D.\n\nAssoc iate Professor\, Institute for Biogenesis Research\n\n\n\n\n\n\n“Foxo3 L ongevity Gene and Effect on Telomeres during Aging."3:00 Ben Fogelgren\, P h.D.\n\nAssociate Professor\, Institute for Biogenesis Research\n\n“Fail ure to Form an Epithelial Barrier during Ureter Development Can Result In Obstructive Kidney Disease”\n\n3:15 Coffee Break/Posters\n\nSCIENTIFIC S ESSION 4: Moderator\, Stefan Moisyadi\, PhD\n\nAssociate Professor\, Insti tute for Biogenesis Research\n\n3:45 Jon Oatley\, PhD\nAssociate Professor \, Director\, Center for Reproductive Biology Washington State University\ n\n"Applications of Germline Ablation\, Engineering\, and Transplantation in Biomedical Research and Animal Agriculture"\n\n4:45 Ryuzo Yanagimachi\, PhD\nProfessor Emeritus\, Department of Anatomy\, Biochemistry\, and Phys iology\n\n“Lessons for Scientists”\n\n5:00 W. Steven Ward\, PhD\nDirec tor\, Institute for Biogenesis Research\n\n \;\n\n\n\n\n\n\n \;\n\ n\n \; LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:180@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180810T170000 DTEND;TZID=Pacific/Honolulu:20180810T203000 DTSTAMP:20180801T213412Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=5th-annual-e-hooulu-h aumana-presentation-by-the-2018-mhirt-students SUMMARY:5th Annual E Ho‘oulu Haumana Presentation by the 2018 MHIRT Stude nts DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:179@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180801T090000 DTEND;TZID=Pacific/Honolulu:20180801T100000 DTSTAMP:20180729T002146Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-for-yukie-m-lloyd-antibody-response-to-the-plasmodium-falciparum- antigen-var2csa-in-pregnant-women-residing-in-malaria-endemic-areas SUMMARY:Tropical Medicine PhD Defense for Yukie M. Lloyd: “Antibody Respo nse to the Plasmodium falciparum Antigen VAR2CSA in Pregnant Women Residin g in Malaria Endemic Areas” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:178@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180702T140000 DTEND;TZID=Pacific/Honolulu:20180702T150000 DTSTAMP:20180628T012241Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=fulbright-visiting-sc holar-professor-sm-kamruzzaman-seminar-ii-transboundary-animal-diseases-in -south-asia-concerns-and-challenge SUMMARY:Fulbright Visiting Scholar Professor SM Kamruzzaman Seminar: "II. T ransboundary Animal Diseases in South Asia: Concerns and Challenge" DESCRIPTION: LOCATION:University of Hawaii\, Agricultural Science Bldg Rm. 219\, 1955 Ea st West Rd.\, Honolulu\, United States GEO:21.3027476;-157.8141122 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1955 East West Rd.\, Honolu lu\, United States;X-APPLE-RADIUS=100;X-TITLE=University of Hawaii\, Agric ultural Science Bldg Rm. 219:geo:21.3027476,-157.8141122 END:VEVENT BEGIN:VEVENT UID:177@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180702T100000 DTEND;TZID=Pacific/Honolulu:20180702T110000 DTSTAMP:20180628T012104Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=fulbright-visiting-sc holar-professor-sm-kamruzzaman-seminar-i-medicinal-plant-with-anti-platele t-activity SUMMARY:Fulbright Visiting Scholar Professor SM Kamruzzaman Seminar: "I. Me dicinal Plant with Anti-Platelet Activity" DESCRIPTION: LOCATION:University of Hawaii\, Agricultural Science Bldg Rm. 219\, 1955 Ea st West Rd.\, Honolulu\, United States GEO:21.3027476;-157.8141122 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1955 East West Rd.\, Honolu lu\, United States;X-APPLE-RADIUS=100;X-TITLE=University of Hawaii\, Agric ultural Science Bldg Rm. 219:geo:21.3027476,-157.8141122 END:VEVENT BEGIN:VEVENT UID:176@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180531T130000 DTEND;TZID=Pacific/Honolulu:20180531T140000 DTSTAMP:20180529T194031Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-jasmine-tyson-title-developing-novel-serological-tests-to-d istinguish-different-flavivirus-infections SUMMARY:Tropical Medicine MS Thesis Defense: Jasmine Tyson\, Title: "Develo ping novel serological tests to distinguish different flavivirus infection s" DESCRIPTION: END:VEVENT BEGIN:VEVENT UID:175@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180514T120000 DTEND;TZID=Pacific/Honolulu:20180514T130000 DTSTAMP:20180514T195155Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-eosinophils-in-the-cerebrospinal-fluid-by-tim-kuberski-md-fidsa SUMMARY:COBRE/Tropical Medicine Seminar: "Eosinophils in the Cerebrospinal Fluid" by Tim Kuberski\, MD\, FIDSA DESCRIPTION:*This seminar will also be available online via Zoom. Please se e information to connect via Zoom below.\nWeb link for meeting: \;http s://zoom.us/j/305877979\n \;\nCalling in: \;\nDial(for higher qual ity\, dial a number based on your current location): \;\n \;   \;  \;  \; US: +1 408 638 0986 \; or +1 646 558 8665 \; or +1 646 876 9923 \; or +1 669 900 6833 \; or +1 408 638 0968 \ ; or +1 877 853 5257 (Toll Free) or +1 855 880 1246 (Toll Free)\n \; & nbsp\; Meeting ID: \;305 877 979\n \;  \; International number s available: \;https://zoom.us/u/bzdFpFh73\n\n \;\nIt is highly ad vised for participants to install the ZOOM application. you can click on t he download footer link at \;https://zoom.usor directly from \;htt ps://zoom.us/support/download \;\n• For iOS\, visit the Apple App St ore and search "zoom"\n• For Android\, visit Google Play and search "zoo m"\nAfter installing the application\, the participants will click on the Join a Meeting button meeting and it will ask the for a meeting ID #.  \; Enter the meeting ID and that will connect them to the meeting.\n \ ; LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:174@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180504T120000 DTEND;TZID=Pacific/Honolulu:20180504T130000 DTSTAMP:20180504T005133Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-immunity-or-tissue-damage-to-viruses-what-determines-the-outcome-by SUMMARY:Tropical Medicine Seminar: "Immunity or Tissue Damage to Viruses - What Determines the Outcome?" by Barry Rouse\, DVM\, PhD\, DSc\, Universit y of Tennessee DESCRIPTION: LOCATION:JABSOM MEB RM. 202\, 651 Ilalo St\, Honolulu\, HI\, 96813\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St\, Honolulu\, H I\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM MEB RM. 202:ge o:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:172@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180502T120000 DTEND;TZID=Pacific/Honolulu:20180502T130000 DTSTAMP:20180423T230049Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-janis-t-eells-phd-university-of-wisconsin-milwaukee-presents-un blinded-by-the-light-nir-photobiomodulation-in-retinal-disease SUMMARY:COBRE/Tropical Medicine Seminar: Janis T. Eells\, PhD\, University of Wisconsin-Milwaukee presents " Unblinded by the Light: NIR Photobiomodu lation in Retinal Disease" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:171@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180501T100000 DTEND;TZID=Pacific/Honolulu:20180501T110000 DTSTAMP:20180423T225316Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-tropical-medici ne-seminar-richard-dix-phd-georgia-state-university-presents-cytomegalovir us-and-the-eye-aids-related-retinitis-and-beyond SUMMARY:COBRE/Tropical Medicine Seminar: Richard Dix\, PhD\, Georgia State University presents "Cytomegalovirus and the Eye: AIDS-related Retinitis a nd Beyond" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:173@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180425T170000 DTEND;TZID=Pacific/Honolulu:20180425T190000 DTSTAMP:20180424T004230Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=world-malaria-day-201 8 SUMMARY:World Malaria Day 2018 DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:170@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180425T120000 DTEND;TZID=Pacific/Honolulu:20180425T130000 DTSTAMP:20180423T192303Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-cait lin-flores-presents-immunosignatures-a-tool-for-predicting-efficacy-of-fil ovirus-vaccine-candidates SUMMARY:TRMD 690 Seminar: Caitlin Flores presents "Immunosignatures: A Tool for Predicting Efficacy of Filovirus Vaccine Candidates" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:167@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180423T100000 DTEND;TZID=Pacific/Honolulu:20180423T110000 DTSTAMP:20180417T191702Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-car eer-development-webinar-anna-babakhanyan-phd-mbt-presents-alternative-care ers-for-stem-phd-students-science-education SUMMARY:Tropical Medicine Career Development Webinar: Anna Babakhanyan\, Ph D\, MBT presents "Alternative Careers for STEM PhD Students: Science Educa tion" DESCRIPTION:This webinar is also available remotely:\n\n Join from PC\, Ma c\, Linux\, iOS or Android: https://zoom.us/j/282204183\n Or iPhone one-t ap :\n\n US: +14086380968\,\,282204183# \; or +16468769923\,\,2822041 83#\n\n\n Or Telephone:\n\n Dial(for higher quality\, dial a number base d on your current location): US: +1 408 638 0968 \; or +1 646 876 9923  \; or +1 669 900 6833 \; or +1 877 853 5257 (Toll Free) or +1 855 880 1246 (Toll Free)\n\n\n\n \; \; \; Meeting ID: 282 204 183 \n\n \; \; \; International numbers available: https://zoom.us /u/rRhMlH5h LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:168@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180421T083000 DTEND;TZID=Pacific/Honolulu:20180421T153000 DTSTAMP:20180417T232201Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2018-hi-asm-spring-me eting SUMMARY:2018 HI-ASM Spring Meeting DESCRIPTION:\n\n \; LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:165@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180418T120000 DTEND;TZID=Pacific/Honolulu:20180418T130000 DTSTAMP:20180416T193643Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=biomedical-science-an d-health-disparities-symposium-keynote-address-by-dr-keshav-k-singh-mitoch ondria-in-health-and-health-disparities SUMMARY:Biomedical Science and Health Disparities Symposium Keynote Address by Dr. Keshav K. Singh: "Mitochondria in Health and Health Disparities" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 202\, 651 Ilalo St\, Honolulu\, HI\, 96813\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St\, Honolulu\, H I\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educat ion Bldg. Rm 202:geo:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:169@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180418T120000 DTEND;TZID=Pacific/Honolulu:20180418T130000 DTSTAMP:20180418T190437Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-an-o verview-of-human-papilloma-virus-hpv-and-cervical-cancer-by-payal-maharaj SUMMARY:TRMD 690 Seminar: "An overview of human papilloma virus (HPV) and c ervical cancer" by Payal Maharaj DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:166@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu;VALUE=DATE:20180418 DTEND;TZID=Pacific/Honolulu;VALUE=DATE:20180420 DTSTAMP:20180416T194103Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=biomedical-science-an d-health-disparities-symposium SUMMARY:Biomedical Science and Health Disparities Symposium DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:160@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180412T091500 DTEND;TZID=Pacific/Honolulu:20180412T104500 DTSTAMP:20180324T015751Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=illumina-next-generat ion-sequencing-seminar-uh-cancer-center SUMMARY:Illumina Next Generation Sequencing Seminar\, UH Cancer Center DESCRIPTION:Registration Required:  \;eventregistration.illumina.com/UH ISeq100\n LOCATION:UH Cancer Center Room 301\, 701 Ilalo St.\, Honolulu\, HI\, 96813\ , United States GEO:21.2952803;-157.8634283 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=701 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=UH Cancer Center Roo m 301:geo:21.2952803,-157.8634283 END:VEVENT BEGIN:VEVENT UID:163@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180411T120000 DTEND;TZID=Pacific/Honolulu:20180411T130000 DTSTAMP:20180409T232645Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-690-seminar-by-b rooks-mitchell-innate-and-adaptive-immunity-dynamics-in-the-evolution-of-h iv-associated-comorbidities SUMMARY:TRMD 690 Seminar by Brooks Mitchell: "Innate and Adaptive Immunity Dynamics in the Evolution of HIV-associated Comorbidities" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:164@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180410T140000 DTEND;TZID=Pacific/Honolulu:20180410T160000 DTSTAMP:20180409T233226Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=sii-seminar-mycobacte ria-in-the-pacific SUMMARY:SII Seminar: "Mycobacteria in the Pacific" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:162@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180404T120000 DTEND;TZID=Pacific/Honolulu:20180404T130000 DTSTAMP:20180402T202812Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-by-scott-bowler-pd-1-and-tigit-cd4-t-cells-predict-2-year-progression -of-coronary-artery-calcium-in-treated-hiv SUMMARY:Tropical Medicine Seminar by Scott Bowler: "PD-1+ AND TIGIT+ CD4+ T CELLS PREDICT 2 YEAR PROGRESSION OF CORONARY ARTERY CALCIUM IN TREATED HI V" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:161@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180404T000000 DTEND;TZID=Pacific/Honolulu:20180404T170000 DTSTAMP:20180330T024637Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-charles -wood-candidate-for-associate-dean-of-research-research-and-capacity-build ing-on-aids-associated-malignancies-in-sub-saharan-africa SUMMARY:Seminar by Dr. Charles Wood\, Candidate for Associate Dean of Resea rch: "Research and Capacity Building on AIDS associated Malignancies in Su b-Saharan Africa" DESCRIPTION: LOCATION:MEB 301\, John A Burns School of Medicine\, 651 Ilalo St.\, Honolu lu\, HI\, 96813\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=MEB 301\, John A Bur ns School of Medicine:geo:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:159@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180321T120000 DTEND;TZID=Pacific/Honolulu:20180321T130000 DTSTAMP:20180320T205310Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=thomas-premeaux-semin ar-unraveling-mechanisms-driving-hiv-age-related-comorbidities SUMMARY:Thomas Premeaux Seminar: "Unraveling Mechanisms Driving HIV Age-rel ated Comorbidities" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:158@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180314T120000 DTEND;TZID=Pacific/Honolulu:20180314T130000 DTSTAMP:20180313T205614Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-by-daniel-strange-in-vitro-investigation-of-zika-virus-infection-and- persistence-in-the-human-testes SUMMARY:Tropical Medicine Seminar by Daniel Strange: "In vitro investigatio n of Zika virus infection and persistence in the human testes" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:157@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180313T120000 DTEND;TZID=Pacific/Honolulu:20180313T130000 DTSTAMP:20180308T023616Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-seminar-keeton-krause-presents-defining-the-role-of-alpha-m acroglobulins-in-the-pathogenesis-of-flavivirus-encephalitis SUMMARY:Tropical Medicine MS Thesis Defense Seminar: Keeton Krause presents "Defining the Role of Alpha-Macroglobulins in the Pathogenesis of Flavivi rus Encephalitis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:155@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180309T140000 DTEND;TZID=Pacific/Honolulu:20180309T160000 DTSTAMP:20180303T180626Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pacific-center-for-em erging-infectious-diseases-research-2018-cobre-mini-symposium SUMMARY:Pacific Center for Emerging Infectious Diseases Research 2018 COBRE Mini-Symposium DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 202\, 651 Ilalo St.\, Honolulu\, HI\, 96813\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educa tion Bldg. Rm 202:geo:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:156@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180307T120000 DTEND;TZID=Pacific/Honolulu:20180307T130000 DTSTAMP:20180307T190729Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -student-liana-medina-presents-a-recombinant-subunit-based-zika-vaccine-is -efficacious-in-nonhuman-primates SUMMARY:Tropical Medicine PhD Student Liana Medina presents "A Recombinant Subunit Based Zika Vaccine is Efficacious in Nonhuman Primates" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:154@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180228T000000 DTEND;TZID=Pacific/Honolulu:20180228T130000 DTSTAMP:20180228T004631Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-by-aneesa-golshan-nanoparticles-as-delivery-systems-for-malaria-vacci nes SUMMARY:Tropical Medicine Seminar by Aneesa Golshan: "Nanoparticles as Deli very Systems for Malaria Vaccines" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg Rm 302\, 651 Ilalo St\, Honolulu\, H I\, 96813\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St\, Honolulu\, H I\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educat ion Bldg Rm 302:geo:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:152@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180215T090000 DTEND;TZID=Pacific/Honolulu:20180215T120000 DTSTAMP:20180209T010733Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=dna-seq-mutation-data -analysis-workshop-presented-by-jabsom-bioinformatics-and-biostatistics-co res SUMMARY:DNA-Seq Mutation Data Analysis Workshop Presented by JABSOM Bioinfo rmatics and Biostatistics Cores DESCRIPTION:Limited number of seats available For reservations\, please ema il:\n\n\n\n\nbioinf@hawaii.edu or vedbar@hawaii.edu\n\n\n\n\n LOCATION:Jabsom MEB Computer Lab 107D\, 651 Ilalo St.\, Honolulu\, HI\, 968 13\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=Jabsom MEB Computer Lab 107D:geo:21.2964863,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:153@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180214T120000 DTEND;TZID=Pacific/Honolulu:20180214T130000 DTSTAMP:20180214T192801Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-by-jasmine-tyson-developing-novel-serological-tests-to-distinguish-di fferent-flavivirus-infections SUMMARY:Tropical Medicine Seminar by Jasmine Tyson: "Developing Novel Serol ogical Tests to Distinguish Different Flavivirus Infections" DESCRIPTION: LOCATION:JABSOM MEB 302\, 651 Ilalo St\, Honolulu\, HI\, United States GEO:21.2964863;-157.86377830000004 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St\, Honolulu\, H I\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM MEB 302:geo:21.2964863 ,-157.86377830000004 END:VEVENT BEGIN:VEVENT UID:151@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180122T120000 DTEND;TZID=Pacific/Honolulu:20180122T130000 DTSTAMP:20180118T011500Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=mary-woolley-presiden t-researchamerica-presents-your-role-in-changing-hearts-and-minds-for-scie nce SUMMARY:Mary Woolley\, President\, Research!America presents "Your Role in Changing Hearts and Minds for Science" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:145@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180116T080000 DTEND;TZID=Pacific/Honolulu:20180117T080000 DTSTAMP:20171128T230341Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2018-update-hawai%ca% bbi-to-zero-hiv-cure-and-prevention-effortsday-1-full-day-conference-tues- january-16-2018-8am-430pm-for-the-public-and-hiv-community-6-5-cme-credits -available-day-2-strate SUMMARY:2018 Update: Hawaiʻi to Zero HIV Cure and Prevention Efforts DESCRIPTION:Day 1: Full Day Conference\nTues\, January 16\, 2018\, 8AM-4:30 PM\nFor the Public and HIV Community\n6.5 CME Credits Available\n\nDay 2: Strategy Working Group\nWed\, January 17\, 2018\, 8AM-3:30PM\nFor HIV Comm unity Leaders and Health Professionals\nFor Day 2\, please email hicfa@haw aii.edu for confirmation of attendance.\n\nLocation:\nUniversity of Hawai ʻi at Kakaʻako\nSullivan Conference Center\n701 Ilalo St.\, Honolulu\, H I 96813\nEvent Registration\nFree registration here: https://www.eventbrit e.com/e/2018-update-hawaii-to-zero-hiv-cure-and-prevention-efforts-tickets -39496763884\n\nEVENT DETAILS LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:150@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20180110T120000 DTEND;TZID=Pacific/Honolulu:20180110T130000 DTSTAMP:20180104T202626Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-seminar-dr-keit h-dunker-indiana-university-schools-of-medicine-bioinformatics-presents-a- toolkit-for-developmental-biology-intrinsically-disordered-proteins-altern ative-splicing-and-po SUMMARY:COBRE Seminar: Dr. Keith Dunker\, Indiana University Schools of Med icine & Bioinformatics presents "A Toolkit for Developmental Biology: Intr insically Disordered Proteins\, Alternative Splicing\, and Post-translatio nal Modification" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:149@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171221T120000 DTEND;TZID=Pacific/Honolulu:20171221T131500 DTSTAMP:20171220T215340Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-to-zero-semina rs-turbo-culosis-does-siv-enhance-tb-disease-missing-the-forest-for-the-zi kvs-by-dr-shelby-oconnor-and-dr-david-oconnor SUMMARY:Hawai‘i to Zero Seminars: "Turbo-culosis: Does SIV enhance TB dis ease?" & "Missing the forest for the ZIKVs" by Dr. Shelby O'Connor and Dr. David O'Connor DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:148@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171219T120000 DTEND;TZID=Pacific/Honolulu:20171219T130000 DTSTAMP:20171208T213740Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-seminar-non-vir al-gene-delivery-from-regenerative-medicine-to-cancer-immunotherapy-by-ste phany-zheng-phd-johns-hopkins-school-of-medicine SUMMARY:COBRE Seminar: "Non-viral gene delivery: From regenerative medicine to cancer immunotherapy" by Stephany Zheng\, PhD\, Johns Hopkins School o f Medicine DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:146@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171211T120000 DTEND;TZID=Pacific/Honolulu:20171211T130000 DTSTAMP:20171205T195845Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-seminar-single- injection-vaccines-by-dr-ana-jaklenec-massachusetts-institute-of-technolog y SUMMARY:COBRE Seminar: "Single-Injection Vaccines" by Dr. Ana Jaklenec\, Ma ssachusetts Institute of Technology DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:147@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171206T120000 DTEND;TZID=Pacific/Honolulu:20171206T130000 DTSTAMP:20171206T191551Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-lauren-ching-presents-association-of-immune-signatures-with-acute- phase-of-kawasaki-disease SUMMARY:Tropical Medicine MS Student Lauren Ching presents "Association of Immune Signatures with Acute Phase of Kawasaki Disease" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:137@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171202T120000 DTEND;TZID=Pacific/Honolulu:20171202T150000 DTSTAMP:20171011T234651Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-branch-asm-fal l-meeting-lecture-dr-ilhelm-powers-aging-and-immune-function-from-molecula r-mechanisms-to-intervention SUMMARY:Hawaii Branch ASM Fall Meeting Lecture\, Dr. Ilhelm Powers: "Aging and Immune Function: from molecular mechanisms to intervention" DESCRIPTION:EARLY ONLINE REGISTRATION\n\n LOCATION:Treetops Restaurant\, 3737 Manoa Rd.\, Honolulu\,\, HI\, 96822\, U nited States GEO:21.3293809;-157.8018682 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=3737 Manoa Rd.\, Honolulu\, \, HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=Treetops Restaura nt:geo:21.3293809,-157.8018682 END:VEVENT BEGIN:VEVENT UID:142@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171201T183000 DTEND;TZID=Pacific/Honolulu:20171201T194500 DTSTAMP:20171128T020853Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=annual-world-aids-day -ceremony SUMMARY:Annual World AIDS Day Ceremony DESCRIPTION:World AIDS Day - December 1st \;2017\n\n\n\n \;\n\n&nbs p\;  \;World AIDS Day 2017 will be observed on Friday\, December 1st&n bsp\;at the Cathedral of St. Andrew in downtown Honolulu. \; The main ceremony begins at 6:30 PM with a program of music\, hula\, and the annual award given by the Department of Health for ‘outstanding contributions in providing HIV/AIDS services in Hawaii.\n\nThis year the award goes to P aul Groesbeck who is retiring after 25 years of dedicated and successful s ervice as Executive Director of the Life Foundation\, Hawai’i’s first and largest AIDS service organization.\n\nThe program begins with the keik i of Kananiokeakua School of Hula dancing “Patchwork Quilt\,” with Kea li’i Reichel singing in accompaniment.\n\nThe music continues with Karol ’s Karolers performing several \;a cappella \;songs. \; Cath y Lowenburg\, Kiit Dylan Arrieta\, and Emily Krause will close the program with a contemporary selection. \; A reception hosted by Slow Food O ’ahu follows.\n\nBefore the main ceremony\, the Hawaii Center for AIDS w ill offer a \;“Living Healthy with HIV” \;presentation and com munity forum at 5:30 PM in Davies Hall at St. Andrew’s. \; This will include the latest research\, tips on diet and exercise\, and Q &\; A.  \; The public is invited to this and all World AIDS Day events.\n\nKa pi’olani Community College will observe World AIDS Day on Thursday\, Nov ember 30\, from 10 AM – 1 PM on the KCC campus Great Lawn. Contact \ ;kccserve@hawaii.edu \;for more information on this event.\n\nWorld AI DS Day was established in 1988 by the World Health Organization as a day f or remembering those lost to HIV/AIDS and for commitment to ending the spr ead of the epidemic. \; The World AIDS Day Hawai’i Committee is a ne twork of volunteers representing community organizations\, religious congr egations\, government agencies\, school groups\, and concerned individuals who plan and organize the observance each year. \; All are welcome to participate.\n\nWorld AIDS Day Hawai’i Committee\n\nContact: \; Su Yates\, Life Foundation \;syates@lifefoundation.org\n\nwww.worldaidsda yhawaii.org LOCATION:Cathedral of Saint Andrew\, 229 Queen Emma Square\, Honolulu\, HI\ , 96813\, United States GEO:21.3097765;-157.85737489999997 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=229 Queen Emma Square\, Hon olulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=Cathedral of Saint Andrew:geo:21.3097765,-157.85737489999997 END:VEVENT BEGIN:VEVENT UID:141@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171201T120000 DTEND;TZID=Pacific/Honolulu:20171201T130000 DTSTAMP:20171124T191549Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=asm-guest-speaker-dr- ilhem-messaoudi-powers-presents-mechanisms-of-protection-conferred-by-reco mbinant-vesicular-stomatitis-virus-based-vaccines-against-filoviruses SUMMARY:ASM Guest Speaker Dr. Ilhem Messaoudi-Powers presents "Mechanisms o f protection conferred by recombinant Vesicular Stomatitis Virus-based vac cines against filoviruses" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:144@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171130T120000 DTEND;TZID=Pacific/Honolulu:20171130T130000 DTSTAMP:20171128T202012Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-center-for-aid s-seminar-renin-angiotensin-system-discovering-what-we-did-not-know-by-sta n-gee-louie-pharm-d-usc-school-of-pharmacy SUMMARY:Hawaii Center for AIDS Seminar: "Renin-Angiotensin System: Discover ing What We Did Not Know" by Stan Gee Louie\, Pharm.D.\, USC School of Pha rmacy DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:143@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171129T120000 DTEND;TZID=Pacific/Honolulu:20171129T130000 DTSTAMP:20171128T190413Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-francine-azouz-presents-defining-the-function-of-schlafen4-in-flav ivirus-encephalitis SUMMARY:Tropical Medicine MS Student Francine Azouz presents "Defining the function of Schlafen4 in Flavivirus encephalitis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:140@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171115T093000 DTEND;TZID=Pacific/Honolulu:20171115T103000 DTSTAMP:20171108T202126Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=webinar-the-power-of- prevention-promoting-the-hpv-vaccine-for-cancer-prevention SUMMARY:Webinar: The Power of Prevention - Promoting the HPV Vaccine for Ca ncer Prevention DESCRIPTION:Webinar: The Power of Prevention - Promoting the HPV Vaccine fo r Cancer Prevention\n\nWhen: Wednesday\, November 15\, 2:30 - 3:30 p.m. ET \n\nHosted by: The Prevent Cancer Foundation's Think About the Link® camp aign and Dialogue for Action® conference\n\nThink About the Link® spokes person and cervical cancer survivor Marissa Jaret Winokur will share her s tory of survival and perspective on the HPV vaccine as a parent.\n\nIn thi s presentation we will also examine the impact of HPV-related cancers on v ulnerable populations\, debunk myths and misinformation about the HPV vacc ine and share opportunities to improve HPV vaccine advocacy in the U.S.\n\ nJoin us for what promises to be a highly informative session - register t oday! (www.preventcancer.org/webinar)\n\nPlease contact Gabrelle Taylor at gabrelle.taylor@preventcancer.org with questions. END:VEVENT BEGIN:VEVENT UID:131@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171101T120000 DTEND;TZID=Pacific/Honolulu:20171101T130000 DTSTAMP:20171003T002530Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=esther-ellis-phd-us-v irgin-islands-epidemiologist-presents-bench-scientist-to-stateterritorial- epidemiologist-pathway-from-lab-to-applied-public-health-career SUMMARY:RESCHEDULED: Esther Ellis\, PhD\, US Virgin Islands Epidemiologist presents "Bench Scientist to State/Territorial Epidemiologist: Pathway fro m Lab to Applied Public Health Career" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:139@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171025T120000 DTEND;TZID=Pacific/Honolulu:20171025T130000 DTSTAMP:20171023T195222Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-phd-studen t-joanna-kettlewell-optimization-of-an-in-vitro-blood-brain-barrier-model SUMMARY:Seminar by PhD Student Joanna Kettlewell: "Optimization of an in vi tro blood-brain barrier model" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:138@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171018T120000 DTEND;TZID=Pacific/Honolulu:20171018T130000 DTSTAMP:20171017T004518Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=trmd-seminar-recombin ant-zika-virus-subunits-are-immunogenic-and-efficacious-in-mice-by-albert- to-phd-candidate SUMMARY:TRMD Seminar: "Recombinant Zika Virus Subunits are Immunogenic and Efficacious in Mice" by Albert To\, PhD Candidate DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:136@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171011T120000 DTEND;TZID=Pacific/Honolulu:20171011T130000 DTSTAMP:20171010T194200Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-on-angiostrongyliasis-eosinophilic-meningitis-rat-lungworm-disease-by -william-gosnell-phd-kenton-kramer-phd-and-dewolfe-miller-phd SUMMARY:Tropical Medicine Seminar on Angiostrongyliasis (Eosinophilic Menin gitis\, Rat Lungworm Disease) by William Gosnell\, PhD\, Kenton Kramer\, P hD\, and DeWolfe Miller\, PhD DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:135@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171010T101500 DTEND;TZID=Pacific/Honolulu:20171010T111500 DTSTAMP:20171004T194251Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-seminar-dr-chri stopher-broder-uniformed-services-university-of-the-health-sciences-presen ts-hendra-virus-and-nipah-virus-therapy-and-vaccine SUMMARY:COBRE Seminar: Dr. Christopher Broder\, Uniformed Services Universi ty of the Health Sciences presents "Hendra Virus and Nipah Virus Therapy a nd Vaccine" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:134@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20171004T120000 DTEND;TZID=Pacific/Honolulu:20171004T130000 DTSTAMP:20170928T030852Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-jennife r-honda-national-jewish-health-denver-environmental-host-and-nontuberculou s-mycobacterial-factors-that-interact-to-cause-lung-disease-in-hawaii SUMMARY:Seminar by Dr. Jennifer Honda\, National Jewish Health\, Denver: En vironmental\, Host\, and Nontuberculous Mycobacterial Factors that Interac t to Cause Lung Disease in Hawai‘i” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:133@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170926T101500 DTEND;TZID=Pacific/Honolulu:20170926T111500 DTSTAMP:20170922T195013Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2017-dr-windsor-mary- cutting-lecture-drugs-for-neglected-tropical-diseases-current-challenges-a nd-future-opportunities-by-dr-abhay-r-satoskar SUMMARY:2017 Dr. Windsor & Mary Cutting Lecture: "Drugs for Neglected Tropi cal Diseases: Current challenges and future opportunities" by Dr. Abhay R. Satoskar DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:132@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170920T120000 DTEND;TZID=Pacific/Honolulu:20170920T130000 DTSTAMP:20170914T190600Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-abhijit e-date-daniel-k-inouye-college-of-pharmacy-nanomedicine-for-the-prevention -and-treatment-of-infectious-diseases SUMMARY:Seminar by Dr. Abhijite Date\, Daniel K. Inouye College of Pharmacy : "Nanomedicine for the prevention and treatment of infectious diseases" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:130@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170830T130000 DTEND;TZID=Pacific/Honolulu:20170830T140000 DTSTAMP:20170825T190658Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=developmental-reprodu ctive-biology-seminar-regulation-of-blastocyst-formation-by-mevalonate-pat hway-by-dr-vernadeth-alarcon SUMMARY:Developmental & Reproductive Biology Seminar: "Regulation of blasto cyst formation by mevalonate pathway" by Dr. Vernadeth Alarcon DESCRIPTION: LOCATION:Institute of Biogenesis Research Conference Room\, 1960 East West Rd.\, Honolulu\, HI\, United States GEO:21.3007234;-157.81466239999997 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1960 East West Rd.\, Honolu lu\, HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Institute of Biogenesis Research Conference Room:geo:21.3007234,-157.81466239999997 END:VEVENT BEGIN:VEVENT UID:129@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170823T120000 DTEND;TZID=Pacific/Honolulu:20170823T130000 DTSTAMP:20170821T192011Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-rediscovering-the-history-of-hansens-disease-in-kalaupapa SUMMARY:Tropical Medicine Seminar: "Rediscovering the History of Hansen's D isease in Kalaupapa" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:128@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170801T103000 DTEND;TZID=Pacific/Honolulu:20170801T113000 DTSTAMP:20170717T192848Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=summer-2017-alicata-a ward-presentation SUMMARY:Summer 2017 Alicata Award Presentation DESCRIPTION: LOCATION:JABSOM BioScience Bldg. Rm 320\, 651 Ilalo St.\, Honolulu\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm 320:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:127@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170628T120000 DTEND;TZID=Pacific/Honolulu:20170628T130000 DTSTAMP:20170627T192728Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-fac ulty-seminar-dr-kalpana-kallianpur-tata-presents-neuroimaging-research-at- the-hawaii-center-for-aids SUMMARY:Tropical Medicine Faculty Seminar: Dr. Kalpana Kallianpur presents "Neuroimaging Research at the Hawai‘i Center for AIDS" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm. 302\, 651 Ilalo St.\, Honolulu\ , HI\, 96813\, United States GEO:21.2960372;-157.86337909999997 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Educa tion Bldg. Rm. 302:geo:21.2960372,-157.86337909999997 END:VEVENT BEGIN:VEVENT UID:126@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170622T130000 DTEND;TZID=Pacific/Honolulu:20170622T140000 DTSTAMP:20170620T001815Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -dissertation-defense-by-eleanore-chuang-a-tale-of-two-viruses-hpv-infecti on-and-associated-anal-dysplasia-among-hawaii-hiv-seropositive-patients-an d-related-hiv-seroconversio SUMMARY:Tropical Medicine PhD Dissertation Defense by Eleanore Chuang: "A T ale of Two Viruses: HPV Infection and Associated Anal Dysplasia Among Hawa ii HIV-Seropositive Patients and Related HIV Seroconversion Risk in a Thai Population" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:124@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170622T110000 DTEND;TZID=Pacific/Honolulu:20170622T120000 DTSTAMP:20170606T225248Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-david-siemann-presents-zika-virus-infects-human-sertoli-cel ls-and-trespasses-the-blood-testis-barrier-to-gain-entry-into-the-seminife rous-epithelium SUMMARY:Tropical Medicine MS Thesis Defense: David Siemann presents "Zika v irus infects human Sertoli cells and trespasses the blood-testis barrier t o gain entry into the seminiferous epithelium" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:123@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170621T110000 DTEND;TZID=Pacific/Honolulu:20170621T120000 DTSTAMP:20170606T214405Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -dissertation-defense-by-nelson-lazaga-investigation-of-archetype-human-po lyomavirus-jc-cellular-tropism-and-genomic-alterations-in-jc-virus-pathoge nesis SUMMARY:Tropical Medicine PhD Dissertation Defense by Nelson Lazaga: "Inves tigation of Archetype Human Polyomavirus JC Cellular Tropism and Genomic A lterations in JC Virus Pathogenesis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:125@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170615T120000 DTEND;TZID=Pacific/Honolulu:20170615T130000 DTSTAMP:20170612T185030Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-han-ha-youn-presents-dna-vaccine-expressing-mature-dengue-v irus-like-particles-and-development-of-a-serological-test-to-distinguish-d engue-and-zika SUMMARY:Tropical Medicine MS Thesis Defense: Han Ha Youn presents "DNA Vacc ine Expressing Mature Dengue Virus-Like Particles and Development of a S erological Test to Distinguish Dengue and Zika" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:122@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170608T100000 DTEND;TZID=Pacific/Honolulu:20170608T110000 DTSTAMP:20170606T214353Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -dissertation-defense-for-glen-chew-role-of-the-tigit-immune-checkpoint-pa thway-in-the-eradication-of-hiv-infection SUMMARY:Tropical Medicine PhD Dissertation Defense for Glen Chew: "Role of the TIGIT Immune Checkpoint Pathway in the Eradication of HIV Infection" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:121@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170606T100000 DTEND;TZID=Pacific/Honolulu:20170606T110000 DTSTAMP:20170523T205119Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2017-alicata-and-cutt ing-awards SUMMARY:2017 Alicata and Cutting Awards DESCRIPTION: LOCATION:JABSOM BioScience Bldg. Rm 320\, 651 Ilalo St.\, Honolulu\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm 320:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:114@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu;VALUE=DATE:20170601 DTEND;TZID=Pacific/Honolulu;VALUE=DATE:20170603 DTSTAMP:20170513T205239Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-dept-of-health -public-health-preparedness-php-program-conference SUMMARY:Hawaii Dept. of Health Public Health Preparedness (PHP) Program Con ference: BEYOND EBOLA DESCRIPTION:BEYOND EBOLA: PREPARING FOR EMERGING INFECTIOUS DISEASES AND OT HER PUBLIC HEALTH THREATS\n\nDate: June 1 and 2\, 2017\nTime: Registration 8:00 am - 9:00 am\nProgram 9:00 am - 4:30 pm\nLocation: Hilton Waikiki Be ach Hotel\n2500 Kuhio Avenue\nHonolulu\, HI 96815\nParking: Free parking a t the Hilton Waikiki with conference validation\nLunch: Provided\n\nRegist ration is required\n\nRegister here: https://phpbeyondebola.eventbrite.com \n\nQuestions? Concerns? Other info needed? See FAQs below or email: \ ;events@pstpacific.com\n\nView Map\n\nSpeakers:\n\nJune 1 &\; 2\, 2017\ n\n\n\nJune 1\, 2017\n\n\n\nJune 2\, 2017\n\n\n\nFAQs\n\nIs there a fee to attend this event?\nNo\, this event is free of charge to participants.\nT he conference is June 1 - 2. What if I can only attend 1 day?\nYou may reg ister for either one or both days. Space is limited. Please do not registe r for a day you cannot attend.\nWhat are my transportation/parking options for getting to and from the event?\nAttendees are responsible for their o wn transportation to the conference. Validated parking at the Hilton Waiki ki Beach (conference location) will be provided to registered attendees. P lease have conference staff validate your parking ticket.\nIs my registrat ion ticket transferrable?\nNo\, your registration is non-transferrable. Pl ease cancel your registration if you are unable to attend.\nDo I have to b ring my printed ticket to the event?\nNo\, a printed ticket is not needed. \nI have food allergies. Who can I notify?\nWe will do our best to accommo date special diet requests (vegetarian\, food allergies\, etc.) but cannot promise that the hotel caterer will be able to meet every diatary request . Please email events@pstpacific.com with requirements. LOCATION:Hilton Waikiki Beach Hotel\, 2500 Kuhio Avenue\, Honolulu\, HI\, U nited States GEO:21.2752737;-157.8219135 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=2500 Kuhio Avenue\, Honolul u\, HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Hilton Waikiki Beach Hot el:geo:21.2752737,-157.8219135 END:VEVENT BEGIN:VEVENT UID:117@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170515T120000 DTEND;TZID=Pacific/Honolulu:20170515T130000 DTSTAMP:20170509T194131Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=professor-rose-leke-p resents-a-personal-journey-in-global-health-eradication-of-polio-and-malar ia SUMMARY:Professor Rose Leke Presents "A Personal Journey in Global Health: Eradication of Polio and Malaria" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:119@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170512T110000 DTEND;TZID=Pacific/Honolulu:20170512T120000 DTSTAMP:20170509T194611Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=robert-t-wong-md-endo wed-lecturer-vice-admiral-raquel-c-bono-presents-if-i-had-known-then SUMMARY:Robert T. Wong\, MD Endowed Lecturer Vice Admiral Raquel C. Bono pr esents "If I Had Known Then" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:115@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170511T173000 DTEND;TZID=Pacific/Honolulu:20170511T193000 DTSTAMP:20170425T035813Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hep-free-hawaii-movie -night-break-the-silence-around-hepatitis-b-in-hawaii SUMMARY:HEP FREE HAWAII Movie Night: Break the Silence Around Hepatitis B i n Hawaii DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:120@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170510T103000 DTEND;TZID=Pacific/Honolulu:20170510T113000 DTSTAMP:20170509T194934Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=dr-jennifer-manuzak-u niversity-of-washington-presents-effects-of-probiotic-treatment-on-sivhiv- vaccination SUMMARY:Dr. Jennifer Manuzak\, University of Washington presents "Effects o f Probiotic Treatment on SIV/HIV Vaccination" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:118@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170510T000000 DTEND;TZID=Pacific/Honolulu:20170510T130000 DTSTAMP:20170509T194341Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-keeton-krause-seminar-a-guinea-pig-model-of-zika-virus-disease SUMMARY:Tropical Medicine MS Student Keeton Krause Seminar: "A Guinea Pig M odel of Zika Virus Disease" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:116@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170503T120000 DTEND;TZID=Pacific/Honolulu:20170503T130000 DTSTAMP:20170502T003941Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-thomas-premeaux-presents-soluble-immune-checkpoint-receptors-in-hi v-disease-and-hiv-associated-non-aids-conditions SUMMARY:Tropical Medicine MS Student Thomas Premeaux presents "Soluble Immu ne Checkpoint Receptors in HIV Disease and HIV-associated Non-AIDS Conditi ons" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:113@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170425T173000 DTEND;TZID=Pacific/Honolulu:20170425T200000 DTSTAMP:20170419T193526Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2017-world-malaria-da y-jabsom SUMMARY:2017 World Malaria Day @ JABSOM DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:108@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170421T150000 DTEND;TZID=Pacific/Honolulu:20170421T160000 DTSTAMP:20170405T202613Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-kenji-obadia-mfuh-title-infectious-etiologies-of-febrile-illnesse s-in-cameroon SUMMARY:Tropical Medicine PhD Defense: Kenji Obadia Mfuh\, Title: "Infectio us Etiologies of Febrile Illnesses in Cameroon" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:111@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170420T140000 DTEND;TZID=Pacific/Honolulu:20170420T160000 DTSTAMP:20170419T191922Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2017-cobre-mini-sympo sium SUMMARY:2017 COBRE Mini-Symposium DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:109@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170419T150000 DTEND;TZID=Pacific/Honolulu:20170419T160000 DTSTAMP:20170406T234644Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-argon-steel-titlecomparative-characterization-of-dengue-virus-ser otype-2-isolates-from-a-south-pacific-epidemic-sweep SUMMARY:Tropical Medicine PhD Defense: Argon Steel\, Title:"Comparative cha racterization of Dengue virus serotype 2 isolates from a South Pacific epi demic sweep" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:112@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170419T120000 DTEND;TZID=Pacific/Honolulu:20170419T130000 DTSTAMP:20170419T192952Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -student-payal-maharaj-presents-investigation-of-therapeutic-compounds-fro m-fijian-sponge-derived-marine-fungi SUMMARY:Tropical Medicine PhD Student Payal Maharaj presents "Investigation of therapeutic compounds from Fijian sponge derived marine fungi" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:106@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170418T140000 DTEND;TZID=Pacific/Honolulu:20170418T150000 DTSTAMP:20170405T202410Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-samuel-tassi-yunga-title-in-utero-b-cell-responses-to-plasmodium- falciparum-and-risk-of-malaria-during-the-first-year-of-life SUMMARY:Tropical Medicine PhD Defense: Samuel Tassi Yunga\, Title: "In uter o B cell responses to Plasmodium falciparum and risk of malaria during the first year of life." DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:105@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170415T081500 DTEND;TZID=Pacific/Honolulu:20170415T153000 DTSTAMP:20170404T203419Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-asm-spring-mee ting-saturday-april-15-2017-sullivan-conference-center SUMMARY:Hawaii ASM Spring Meeting - Saturday\, April 15\, 2017 @ Sullivan C onference Center DESCRIPTION:For more information: \;http://www.hawaii.edu/scasm/\n\n LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:107@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170413T100000 DTEND;TZID=Pacific/Honolulu:20170413T110000 DTSTAMP:20170405T202310Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -defense-ngu-njei-abanda-title-drug-resistance-in-mycobacterium-tuberculos is-an-investigation-of-drug-transporter-p-glycoprotein-and-an-evaluation-o f-improved-diagnosis-of-d SUMMARY:Tropical Medicine PhD Defense: Ngu Njei Abanda\, Title: "Drug resis tance in Mycobacterium tuberculosis: An Investigation of Drug Transporter P-glycoprotein and An Evaluation of Improved Diagnosis of Drug-resistant T uberculosis in Cameroonian Pulmonary Tuberculosis Patients" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:110@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170412T120000 DTEND;TZID=Pacific/Honolulu:20170412T130000 DTSTAMP:20170410T191219Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-jasmine-tyson-presents-expression-and-purification-of-premembrane- proteins-of-dengue-virus-in-drosophila-cells SUMMARY:Tropical Medicine MS Student Jasmine Tyson presents "Expression and purification of premembrane proteins of dengue virus in drosophila cells" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:104@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170405T120000 DTEND;TZID=Pacific/Honolulu:20170405T130000 DTSTAMP:20170404T202742Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -student-eleanore-chuang-presents-a-tale-of-two-viruses-hpv-infection-and- associated-anal-dysplasia-among-hawaii-hiv-seropositive-patients-and-relat ed-hiv-seroconversion-risk-i SUMMARY:Tropical Medicine PhD Student Eleanore Chuang presents "A Tale of T wo Viruses: HPV infection and associated anal dysplasia among Hawaii HIV-s eropositive patients and related HIV-seroconversion risk in a Thai populat ion" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:103@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170315T120000 DTEND;TZID=Pacific/Honolulu:20170315T130000 DTSTAMP:20170313T200947Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-david-siemann-presents-zika-virus-infects-human-sertoli-cells-and- trespasses-the-blood-testis-barrier-to-gain-entry-into-the-seminiferous-ep ithelium SUMMARY:Tropical Medicine MS Student David Siemann presents "Zika virus inf ects human Sertoli cells and trespasses the blood-testis barrier to gain e ntry into the seminiferous epithelium" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:102@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170308T120000 DTEND;TZID=Pacific/Honolulu:20170308T130000 DTSTAMP:20170306T231039Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-han-ha-youn-presents-development-of-a-serological-test-to-distingu ish-dengue-and-zika SUMMARY:Tropical Medicine MS Student Han Ha Youn presents "Development of a Serological Test to Distinguish Dengue and Zika" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:101@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170302T120000 DTEND;TZID=Pacific/Honolulu:20170302T130000 DTSTAMP:20170228T195509Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=dr-howard-gendelman-p resents-laser-art-advances-in-the-development-of-long-acting-antiretrovira l-therapy-art-can-revolutionize-current-treatments-for-hivaids SUMMARY:COBRE/Tropical Medicine Seminar: Dr. Howard Gendelman presents "LAS ER ART: Advances in the development of long acting antiretroviral therapy (ART) can revolutionize current treatments for HIV/AIDS." DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:100@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170301T120000 DTEND;TZID=Pacific/Honolulu:20170301T130000 DTSTAMP:20170228T194516Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-car eer-development-seminar-ronald-balajadia-chief-hawaii-doh-immunization-bra nch-on-how-did-i-get-here-career-journey-of-a-trop-med-student SUMMARY:Tropical Medicine Career Development Seminar: Ronald Balajadia\, Ch ief\, Hawaii DOH Immunization Branch on "How did I get here?: Career Journ ey of a Trop Med Student" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:99@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170222T120000 DTEND;TZID=Pacific/Honolulu:20170222T130000 DTSTAMP:20170222T003022Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -student-liana-medina-presents-defining-correlates-of-protection-in-nonhum an-primates-vaccinated-with-a-recombinant-subunit-ebola-vaccine SUMMARY:Tropical Medicine PhD Student Liana Medina presents "Defining corre lates of protection in nonhuman primates vaccinated with a recombinant sub unit Ebola vaccine" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:98@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170210T090000 DTEND;TZID=Pacific/Honolulu:20170210T100000 DTSTAMP:20170202T230627Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobrermatrix-ii-semin ar-informational-session-on-the-national-academy-of-medicine-nam-nominatio n-and-election-process-presented-by-dean-jerris-hedges SUMMARY:COBRE/RMATRIX-II Seminar: "Informational session on the National Ac ademy of Medicine (NAM) Nomination and Election Process" presented by Dean Jerris Hedges DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:97@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170201T120000 DTEND;TZID=Pacific/Honolulu:20170201T130000 DTSTAMP:20170126T234124Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-importance-of-building-research-capacity-for-health-in-disadvant aged-global-settings-by-dr-catherine-pirkle-office-of-public-health-studie s-uh-manoa SUMMARY:COBRE/Tropical Medicine Seminar: "Importance of Building Research C apacity for Health in Disadvantaged Global Settings" by Dr. Catherine Pirk le\, Office of Public Health Studies\, UH Manoa DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:95@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170125T120000 DTEND;TZID=Pacific/Honolulu:20170125T130000 DTSTAMP:20170117T235912Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-by-dr-catherine-pirkle-uh-manoa-office-of-public-health-studies- importance-of-building-research-capacity-for-health-in-disadvantaged-globa l-settings SUMMARY:COBRE/Tropical Medicine Seminar by Dr. Catherine Pirkle\, UH Manoa Office of Public Health Studies: "Importance of Building Research Capacity for Health in Disadvantaged Global Settings" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:96@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170125T120000 DTEND;TZID=Pacific/Honolulu:20170125T130000 DTSTAMP:20170123T212543Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-ebola-a-personal-and-viral-journey-by-dr-thomas-crabtree-aspen-medica l-international SUMMARY:Tropical Medicine Seminar: "Ebola: A Personal and Viral Journey" by Dr. Thomas Crabtree\, Aspen Medical International DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:91@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170120T080000 DTEND;TZID=Pacific/Honolulu:20170120T153000 DTSTAMP:20170113T235500Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=asm-workshop-medical- mycology-a-basic-primer-from-the-clinical-diagnostic-laboratory SUMMARY:ASM Workshop: "Medical Mycology: A basic primer from the clinical d iagnostic laboratory" (EXTENDED DEADLINE: January 17\, 2017) DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:94@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170118T120000 DTEND;TZID=Pacific/Honolulu:20170118T130000 DTSTAMP:20170117T215726Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-by-dr-sladjana-prisic-uhm-dept-of-microbiology-role-of-zinc-in-t uberculosis SUMMARY:COBRE/Tropical Medicine Seminar by Dr. Sladjana Prisic\, UHM Dept. of Microbiology: "Role of Zinc in Tuberculosis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:93@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170111T120000 DTEND;TZID=Pacific/Honolulu:20170111T130000 DTSTAMP:20170110T003242Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-car eer-development-seminar-dr-sandra-chang-presents-an-introduction-to-the-na tional-research-mentoring-network-nrmn SUMMARY:Tropical Medicine Career Development Seminar: Dr. Sandra Chang pres ents "An Introduction to the National Research Mentoring Network (NRMN)" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:92@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20170109T110000 DTEND;TZID=Pacific/Honolulu:20170109T120000 DTSTAMP:20161230T005230Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pceidr-seminar-by-dr- yongsheng-bai-indiana-state-university-uncovering-the-splicing-signatures- for-encode-rna-seq-data-using-read-split-fly SUMMARY:PCEIDR Seminar by Dr. Yongsheng Bai\, Indiana State University: "Un covering the Splicing Signatures for ENCODE RNA-Seq Data using Read-Split- Fly" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:90@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161207T120000 DTEND;TZID=Pacific/Honolulu:20161207T130000 DTSTAMP:20161206T204229Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- candidate-lauren-ching-presents-immunopathogenesis-of-kawasaki-disease-ind uced-coronary-artery-dilation-and-aneurysm-formation SUMMARY:Tropical Medicine MS Candidate Lauren Ching presents "Immunopathoge nesis of Kawasaki Disease Induced Coronary Artery Dilation and Aneurysm Fo rmation" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:89@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161201T080000 DTEND;TZID=Pacific/Honolulu:20161201T120000 DTSTAMP:20161130T195223Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2016-update-hawaii-to -zero-hiv-cure-and-prevention-efforts-december-1-2016 SUMMARY:2016 Update: Hawai'i to Zero – HIV Cure and Prevention Efforts De cember 1\, 2016 DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:88@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161130T000000 DTEND;TZID=Pacific/Honolulu:20161130T130000 DTSTAMP:20161128T214921Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-priscilla-seabourn-presents-epigenetic-regulation-of-human-polyoma virus-jc SUMMARY:Tropical Medicine MS Student Priscilla Seabourn presents "Epigeneti c Regulation of Human Polyomavirus JC" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:87@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161129T120000 DTEND;TZID=Pacific/Honolulu:20161129T130000 DTSTAMP:20161128T194349Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-spe cial-seminar-dr-axel-lehrer-presents-protein-potential-insect-cell-express ed-recombinant-viral-proteins-and-their-application-in-the-development-of- vaccines-and-diagnostics SUMMARY:Tropical Medicine Special Seminar: Dr. Axel Lehrer presents "Protei n Potential: Insect Cell-expressed Recombinant Viral Proteins and their Ap plication in the Development of Vaccines and Diagnostics" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:86@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161121T100000 DTEND;TZID=Pacific/Honolulu:20161121T110000 DTSTAMP:20161121T194025Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-to-zero-semina r-immune-based-strategies-targeting-the-viral-reservoir-in-siv-infected-no nhuman-primates-by-dr-mirko-paiardini-emory-vaccine-center SUMMARY:Hawai‘i to Zero Seminar: "Immune Based Strategies Targeting the V iral Reservoir in SIV-Infected Nonhuman Primates" by Dr. Mirko Paiardini\, Emory Vaccine Center DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:85@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161109T120000 DTEND;TZID=Pacific/Honolulu:20161109T130000 DTSTAMP:20161107T193310Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-tropical-m edicine-phd-candidate-kenji-obadia-development-of-non-invasive-technology- for-malaria-diagnosis SUMMARY:Seminar by Tropical Medicine PhD Candidate Kenji Obadia: "Developme nt of Non-Invasive Technology for Malaria Diagnosis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:84@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161102T120000 DTEND;TZID=Pacific/Honolulu:20161102T130000 DTSTAMP:20161101T191756Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -student-samuel-tassi-yunga-presents-the-amount-of-malarial-antigen-a-fetu s-is-exposed-to-influences-infant-susceptibility-to-malaria-an-opinion SUMMARY:Tropical Medicine PhD Student Samuel Tassi Yunga presents: " The Am ount of Malarial Antigen a Fetus is Exposed to\, Influences Infant Suscept ibility to Malaria: An Opinion" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:83@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161026T000000 DTEND;TZID=Pacific/Honolulu:20161026T130000 DTSTAMP:20161021T000003Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-seminar-dr-wayn e-melrose-james-cooke-univ-presents-worms-are-more-dangerous-than-we-think -immuno-modulation-of-the-host-immune-response-by-nematode-parasites SUMMARY:COBRE Seminar: Dr. Wayne Melrose\, James Cooke Univ. presents "Worm s are More Dangerous than We Think: Immuno-modulation of the Host Immune R esponse by Nematode Parasites" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:82@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161019T140000 DTEND;TZID=Pacific/Honolulu:20161019T150000 DTSTAMP:20161014T193617Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-center-for-aid s-seminar-the-hiv-tissue-reservoir-and-use-of-cancer-to-define-a-next-gene ration-therapeutic-approach-by-dr-michael-mcgrath-uc-san-francisco SUMMARY:Hawaii Center for AIDS Seminar: "The HIV tissue reservoir and use o f cancer to define a next generation therapeutic approach"\, by Dr. Michae l McGrath\, UC San Francisco DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:79@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161019T120000 DTEND;TZID=Pacific/Honolulu:20161019T130000 DTSTAMP:20160928T203404Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-youping -deng-director-of-bioinformatics-core-development-of-precision-medicine-th rough-integrative-dna-and-rna-seq-data-analysis SUMMARY:Seminar by Dr. Youping Deng\, Director of Bioinformatics Core: "Dev elopment of Precision Medicine through Integrative DNA- and RNA-seq Data A nalysis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:81@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161012T000000 DTEND;TZID=Pacific/Honolulu:20161012T130000 DTSTAMP:20161011T022916Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=yukie-lloyd-sato-pres ents-immunity-to-malaria-in-pregnancy-evaluating-biological-functions-of-v ar2csa-antibodies-to-predict-clinical-outcome SUMMARY:Yukie Lloyd (Sato) presents "Immunity to Malaria in Pregnancy: Eval uating Biological Functions of VAR2CSA Antibodies to Predict Clinical Outc ome" DESCRIPTION:P LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:80@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20161011T090000 DTEND;TZID=Pacific/Honolulu:20161011T100000 DTSTAMP:20161005T205901Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=micah-tepora-ms-thesi s-defense-safety-and-protective-efficacy-of-respiratory-syncytial-virus-li ke-particles-rsv-vlps-in-a-murine-model SUMMARY:Micah Tepora MS Thesis Defense: "Safety and protective efficacy of respiratory syncytial virus-like particles (RSV VLPs) in a murine model" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:78@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160922T120000 DTEND;TZID=Pacific/Honolulu:20160922T130000 DTSTAMP:20160910T002718Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cyagen-biosciences-se minar-crisprcas9-and-turboknockout-technologies-for-rapid-generation-of-kn ockoutknockin-mouse-models SUMMARY:Cyagen Biosciences Seminar: "CRISPR/Cas9 and TurboKnockout: Technol ogies for Rapid Generation of Knockout/Knockin Mouse Models" DESCRIPTION: LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:77@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160823T120000 DTEND;TZID=Pacific/Honolulu:20160823T130000 DTSTAMP:20160818T173538Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobre-seminar-dr-ralp h-garruto-presents-modeling-reservoir-vector-spatial-and-human-behavioral- risk-of-lyme-disease-in-fragmented-ecospaces-within-built-environments SUMMARY:COBRE Seminar: Dr. Ralph Garruto presents. "Modeling Reservoir\, Ve ctor\, Spatial and Human Behavioral Risk of Lyme Disease in Fragmented Eco spaces within Built Environments" DESCRIPTION:COBRE TMMMP Seminar Ralph Garruto 082316 LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:76@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160728T120000 DTEND;TZID=Pacific/Honolulu:20160728T130000 DTSTAMP:20160714T013244Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-center-for-aid s-presents-deciphering-the-pathophysiology-of-type-2-diabetes-the-right-ph enotype-for-the-right-situation-by-dr-richard-watanabe-phd-keck-school-of- medicine-of-usc SUMMARY:Hawaii Center for AIDS presents: " Deciphering the pathophysiology of type 2 diabetes: the right phenotype for the right situation" by Dr. R ichard Watanabe\, PhD\, Keck School of Medicine of USC DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:75@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160727T120000 DTEND;TZID=Pacific/Honolulu:20160727T130000 DTSTAMP:20160714T012815Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-center-for-aid s-seminar-siv-intra-host-phylodynamics-and-pathogenesis-in-the-macaque-mod el-of-neuroaids-by-dr-marco-salemi-phd-university-of-florida SUMMARY:Hawaii Center for AIDS Seminar: "SIV Intra-host Phylodynamics and P athogenesis in the Macaque Model of neuroAIDS" by Dr. Marco Salemi\, PhD\, University of Florida DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:74@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160629T120000 DTEND;TZID=Pacific/Honolulu:20160629T130000 DTSTAMP:20160627T194446Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=mci-core-seminar-mole cular-and-cellular-immunology-core-bd-biosciences-present-multicolor-flow- cytometer-seminar-optimizing-performance-and-experimental-design-for-multi color-panel-by-lisa-bel SUMMARY:Molecular and Cellular Immunology Core & BD Biosciences Present Mul ticolor Flow Cytometer Seminar: "Optimizing Performance and Experimental D esign for Multicolor Panel" by Lisa Bellemare\, PhD DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 302\, 651 Ilalo St.\, Honolulu\, \, United States GEO:21.2964369;-157.8637169 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education Bldg. Rm 302:geo:21.2964369,-157.8637169 END:VEVENT BEGIN:VEVENT UID:73@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160629T110000 DTEND;TZID=Pacific/Honolulu:20160629T120000 DTSTAMP:20160622T012321Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretrmd-seminar-by- dr-pramila-walpita-mammalian-cell-derived-virus-like-particle-vlp-vaccine- platform SUMMARY:COBRE/TRMD Seminar by Dr. Pramila Walpita: "Mammalian Cell-derived Virus-like Particle (VLP) Vaccine Platform" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:72@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160620T120000 DTEND;TZID=Pacific/Honolulu:20160620T130000 DTSTAMP:20160614T002002Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=dr-jerome-kim-interna tional-vaccine-institute-seoul-korea-presents-discover-develop-deliver-wor k-on-vaccines-for-global-health-at-the-international-vaccine-institute-seo ul SUMMARY:Dr. Jerome Kim\, International Vaccine Institute\, Seoul\, Korea pr esents "Discover\, Develop\, Deliver: Work on Vaccines for Global Health a t the International Vaccine Institute\, Seoul" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:71@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160523T120000 DTEND;TZID=Pacific/Honolulu:20160523T130000 DTSTAMP:20160519T195517Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-why-does-the-yellow-fever-live-attenuated-17d-vaccine-work-by-dr -alan-barrett-sealy-center-for-vaccine-development-univ-texas-medical-bran ch-galeston SUMMARY:COBRE/Tropical Medicine Seminar: "Why Does the Yellow Fever Live-At tenuated 17D Vaccine Work?"\, by Dr. Alan Barrett\, Sealy Center for Vacci ne Development\, Univ Texas Medical Branch\, Galveston DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:70@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160520T000000 DTEND;TZID=Pacific/Honolulu:20160520T130000 DTSTAMP:20160518T185153Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-antiviral-activity-of-favipiravir-against-henipaviruses-by-dr-al exander-freiberg-univ-texas-medical-branch SUMMARY:COBRE/Tropical Medicine Seminar: "Antiviral Activity of Favipiravir Against Henipaviruses" by Dr. Alexander Freiberg\, Univ. Texas Medical Br anch DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:69@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160516T110000 DTEND;TZID=Pacific/Honolulu:20160516T120000 DTSTAMP:20160513T234227Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-breaking-the- sugar-code-of-hiv-latency-by-dr-mohamed-abdel-mohsin-uc-san-francisco SUMMARY:Seminar: "Breaking the Sugar Code of HIV Latency"\, by Dr. Mohamed Abdel-Mohsen\, UC San Francisco DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:68@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160509T120000 DTEND;TZID=Pacific/Honolulu:20160509T130000 DTSTAMP:20160506T220922Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-improving-the-understanding-of-childhood-malnutrition-in-sub-sah aran-africa-by-indi-trepan-md-mph-dtmh-washington-univ-in-st-louis SUMMARY:COBRE/TROPICAL MEDICINE SEMINAR: "Improving the Understanding of Ch ildhood Malnutrition in sub-Saharan Africa" by Indi Trehan\, MD\, MPH\, DT M&H\, Washington Univ. in St. Louis DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:64@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160430T081500 DTEND;TZID=Pacific/Honolulu:20160430T160000 DTSTAMP:20160408T212839Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-branch-asm-201 6-spring-meeting-keynote-speaker-dr-sarah-park-dengue-a-constant-threat-to -paradise SUMMARY:Hawaii Branch ASM 2016 Spring Meeting\, Keynote Speaker Dr. Sarah P ark: "Dengue: A Constant Threat to Paradise " DESCRIPTION:\n\n \;\n\n \;\n\n \;\n\nFull announcement: Hawaii Branch Spring 2016 LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:67@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160427T120000 DTEND;TZID=Pacific/Honolulu:20160427T130000 DTSTAMP:20160426T015206Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=phd-student-eleanore- chuang-presents-detection-of-hiv-dna-and-anal-hpv-genotypes-among-men-who- have-sex-with-men-and-transgender-women-from-the-thailand-test-and-treat-c ohort SUMMARY:PhD student Eleanore Chuang presents "Detection of HIV DNA and anal HPV genotypes among men who have sex with men and transgender women from the Thailand Test and Treat cohort" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:66@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160425T173000 DTEND;TZID=Pacific/Honolulu:20160425T200000 DTSTAMP:20160418T193923Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=jabsom-world-malaria- day-2016-guest-speakers-vernon-e-ansdell-md-kevin-palmer-phd SUMMARY:JABSOM World Malaria Day 2016\, Guest Speakers Vernon E. Ansdell\, MD & Kevin Palmer\, PhD DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:63@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160421T120000 DTEND;TZID=Pacific/Honolulu:20160421T130000 DTSTAMP:20160408T211056Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=roy-t-tanoue-md-endow ed-lectureship-by-cynthia-morris-phd-mph-oregon-health-science-university- why-you-should-care-about-clinical-and-translational-research SUMMARY:Roy T. Tanoue MD Endowed Lectureship by Cynthia Morris\, PhD\, MPH\ , Oregon Health & Science University: “Why you should care about clinica l and translational research” DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:61@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160421T083000 DTEND;TZID=Pacific/Honolulu:20160422T163000 DTSTAMP:20160408T205449Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=jabsom-biomedical-sci ences-health-disparities-symposium-2 SUMMARY:JABSOM Biomedical Sciences & Health Disparities Symposium DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:62@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160420T160000 DTEND;TZID=Pacific/Honolulu:20160420T170000 DTSTAMP:20160408T211746Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=robert-t-wong-endowed -lecture-by-terri-goss-kinzy-phd-robert-wood-johnson-medical-school-transl ation-elongation-factor-3-a-target-for-anti-fungal-development-and-more SUMMARY:Robert T. Wong MD Endowed Lecture by Terri Goss Kinzy\, PhD\, Rober t Wood Johnson Medical School: "Translation Elongation Factor 3: A target for anti-fungal development and more" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:65@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160420T120000 DTEND;TZID=Pacific/Honolulu:20160420T130000 DTSTAMP:20160418T193559Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ms-student-micah-tepo ra-presents-use-of-respiratory-syncytial-virus-like-particles-in-a-murine- model SUMMARY:MS Student Micah Tepora Presents: "Use of Respiratory Syncytial Vir us-like Particles in a Murine Model" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:60@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160330T000000 DTEND;TZID=Pacific/Honolulu:20160330T130000 DTSTAMP:20160329T215406Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=david-siemann-present s-zika-virus-a-newly-emerging-sexually-transmitted-pathogen-unanswered-que stions SUMMARY:David Siemann presents "Zika Virus\, a Newly Emerging Sexually-Tran smitted Pathogen: Unanswered Questions" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:59@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160329T090000 DTEND;TZID=Pacific/Honolulu:20160329T110000 DTSTAMP:20160329T014522Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=pacific-center-for-em erging-infectious-diseases-research-cobre-mini-symposium SUMMARY:Pacific Center for Emerging Infectious Diseases Research (COBRE) Mi ni-Symposium DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm. 202\, 651 Ilalo St.\, Honolulu\ , HI\, United States GEO:21.2964369;-157.8637169 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education Bld g. Rm. 202:geo:21.2964369,-157.8637169 END:VEVENT BEGIN:VEVENT UID:58@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160316T120000 DTEND;TZID=Pacific/Honolulu:20160316T130000 DTSTAMP:20160316T184436Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=phd-student-glen-chew -presents-hiv-specific-cd8-t-cells-and-hiv-eradication SUMMARY:PhD Student Glen Chew presents "HIV-Specific CD8+ T cells and HIV E radication" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:57@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160302T120000 DTEND;TZID=Pacific/Honolulu:20160302T130000 DTSTAMP:20160301T030652Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-alanna-tse ng-identifying-new-flavivirus-targets-for-antiviral-drug-discovery SUMMARY:Seminar by Alanna Tseng: "Identifying New Flavivirus Targets for An tiviral Drug Discovery" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:56@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160224T120000 DTEND;TZID=Pacific/Honolulu:20160224T130000 DTSTAMP:20160224T191004Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=phd-student-nelson-la zaga-presents-infection-characterization-and-pathogenesis-of-in-vitro-urin e-derived-rearranged-polyomavirus-jc SUMMARY:PhD Student Nelson Lazaga presents "Infection\, Characterization\, and Pathogenesis of In Vitro\, Urine-derived\, Rearranged Polyomavirus JC" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:55@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160217T120000 DTEND;TZID=Pacific/Honolulu:20160217T130000 DTSTAMP:20160216T213243Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-phd-studen t-kenji-obadia-beyond-malaria-infectious-etiologies-of-febrile-illnesses-i n-the-tropics SUMMARY:Seminar by PhD Student Kenji Obadia: "Beyond Malaria: Infectious Et iologies of Febrile Illnesses in the Tropics" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:54@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160210T120000 DTEND;TZID=Pacific/Honolulu:20160210T130000 DTSTAMP:20160208T222344Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ms-student-han-ha-you n-presents-dna-vaccine-expressing-mature-dengue-virus-like-particles SUMMARY:MS Student Han Ha Youn presents "DNA Vaccine Expressing Mature Deng ue Virus-Like Particles" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:53@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160203T120000 DTEND;TZID=Pacific/Honolulu:20160203T130000 DTSTAMP:20160129T012919Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ebola-vaccine-seminar -by-dr-beth-ann-coller-executive-director-merck-research-laboratories SUMMARY:Ebola Vaccine Seminar by Dr. Beth-Ann Coller\, Executive Director\, Merck Research Laboratories DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:52@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20160120T000000 DTEND;TZID=Pacific/Honolulu:20160120T130000 DTSTAMP:20160115T191817Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=dr-ivo-sahbandar-pres ents-tracking-the-evolving-hiv-epidemic-in-the-philippines SUMMARY:Dr. Ivo SahBandar presents "Tracking the Evolving HIV Epidemic in T he Philippines" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:51@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151216T120000 DTEND;TZID=Pacific/Honolulu:20151216T130000 DTSTAMP:20151215T205737Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-hiroshi -matsui-hunter-college-weill-medical-college-biotechnology-and-nanotechnol ogy SUMMARY:Seminar by Dr. Hiroshi Matsui\, Hunter College & Weill Medical Coll ege: "Biotechnology and Nanotechnology" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:50@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151215T120000 DTEND;TZID=Pacific/Honolulu:20151215T130000 DTSTAMP:20151208T195312Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-isaac-krau ss-phd-brandeis-univ-on-hiv-vaccine-design-by-directed-evolution-of-glycos tructures SUMMARY:Seminar by Isaac Krauss\, PhD\, Brandeis Univ. on "HIV Vaccine Desi gn by Directed Evolution of Glycostructures" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:49@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151209T000000 DTEND;TZID=Pacific/Honolulu:20151209T130000 DTSTAMP:20151208T070924Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=phd-student-yukie-llo yd-presents-assessing-the-importance-of-functional-abs-in-placental-malari a SUMMARY:PhD Student Yukie Lloyd presents: "Assessing the Importance of Func tional Abs in Placental Malaria" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:48@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151202T000000 DTEND;TZID=Pacific/Honolulu:20151202T130000 DTSTAMP:20151202T201313Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-presentation- by-samuel-tassi-yunga-the-fetal-inflammatory-response-syndrome SUMMARY:Seminar Presentation by Samuel Tassi Yunga: "The Fetal Inflammatory Response Syndrome" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:47@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151125T120000 DTEND;TZID=Pacific/Honolulu:20151125T130000 DTSTAMP:20151123T040532Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ms-thesis-defense-eli se-penvadga-ngati-specificity-of-naturally-acquired-antibodies-that-bind-t o-the-surface-of-var2csa-expressing-infected-erythrocytes SUMMARY:MS Thesis Defense: Elise Penvadga Ngati\, "Specificity of Naturally Acquired Antibodies That Bind to the Surface of VAR2CSA Expressing Infect ed Erythrocytes" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:40@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151114T173000 DTEND;TZID=Pacific/Honolulu:20151114T210000 DTSTAMP:20151010T025046Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-branch-asm-lec ture-by-dr-david-hooper-microbial-ingenuity-the-challenge-of-antimicrobial -resistance SUMMARY:Hawaii Branch ASM Lecture by Dr. David Hooper: "Microbial Ingenuity : The Challenge of Antimicrobial Resistance" DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:0,0 END:VEVENT BEGIN:VEVENT UID:43@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151112T000000 DTEND;TZID=Pacific/Honolulu:20151112T130000 DTSTAMP:20151103T215648Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-dr-mark-horowitz-presents-how-a-common-everyday-virus-like-epste in-barr-virus-can-predispose-for-multiple-sclerosis SUMMARY:COBRE/Tropical Medicine Seminar: Dr. Mark Horowitz presents "How a Common Everyday Virus like Epstein-Barr Virus can Predispose for Multiple Sclerosis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:45@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151110T150000 DTEND;TZID=Pacific/Honolulu:20151110T160000 DTSTAMP:20151104T025756Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=rmatrix-ii-seminar-me thods-challenges-for-conducting-patient-centered-comparative-effectiveness -research-with-dr-doug-landsittel-enact-program SUMMARY:RMATRIX-II Seminar: Methods & Challenges for Conducting Patient-Ce ntered Comparative Effectiveness Research with Dr. Doug Landsittel\, ENACT Program DESCRIPTION:\n\nADDITIONAL SEMINAR AT KAPIOLANI MEDICAL CENTER FOR WOMEN AN D CHILDREN:\n\nNov. 10\, 2015 @ 11:00 – 12:00 pm\, KMCWC Rm. 758\n\nTit le:"Online and Experiential Training in Patient-Centered Outcomes Researc h – a Collaborative Effort to Build Expertise and Infrastructure at Mino rity-Serving Institutions through the ENACT Program" LOCATION:JABSOM Medical Education Bldg.\, Rm. 304\, 651 Ilalo St.\, Honolul u\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Education B ldg.\, Rm. 304:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:44@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu;VALUE=DATE:20151109 DTEND;TZID=Pacific/Honolulu;VALUE=DATE:20151111 DTSTAMP:20151103T215643Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2015-weinman-symposiu m-university-of-hawaii-cancer-center-presents-international-conference-on- mesothelioma-in-populations-exposed-to-naturally-occurring-asbestiform-fib ers SUMMARY:2015 Weinman Symposium - University of Hawaii Cancer Center Present s: "International Conference on Mesothelioma in populations exposed to Nat urally Occurring Asbestiform Fibers" DESCRIPTION: LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\, HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center\, UH Cancer Center:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:46@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151104T120000 DTEND;TZID=Pacific/Honolulu:20151104T130000 DTSTAMP:20151104T024524Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-christie-nakamura-presents-hiv-1-infection-and-the-blood-brain-bar rier SUMMARY:Tropical Medicine MS Student Christie Nakamura presents: HIV-1 Infe ction and the Blood-Brain Barrier DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:42@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151028T120000 DTEND;TZID=Pacific/Honolulu:20151028T130000 DTSTAMP:20151202T201102Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -student-jourdan-posner-presents-human-b-cell-responses-to-prr-ligands SUMMARY:Tropical Medicine PhD Student Jourdan Posner presents: "Human B cel l responses to PRR ligands" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:37@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151022T193000 DTEND;TZID=Pacific/Honolulu:20151022T205500 DTSTAMP:20151008T004044Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hpv-vaccination-is-ca ncer-prevention SUMMARY:Film: Someone You Love - The HPV Epidemic DESCRIPTION:\n\nJoin us for a one­-night screening of “Someone You Love: The HPV Epidemic\,” a powerful documentary about five women whose lives have been changed forever by the human papillomavirus (HPV).\n\nDate: Thu rsday\, October 22\, 2015\nTime: 7:30 – 8:55 pm\nPlace: Consolidated The atres Kahala 8\n4211 Waialae Avenue\, Honolulu\, HI 96816\nCost: $5.00 per person (proceeds from ticket sales will be used for future HPV-education activities)\n\nPurchase your ticket online at www.immunizehawaii.org.\n\nA pproximately 50 women in Hawaii are diagnosed with invasive cervical cance r and another 6 women die from the disease each year. HPV can cause six di fferent types of cancers in both men and women. Each year in the United St ates\, about 12\,000 women get cervical cancer and about 4\,000 are expect ed to die from it.\n\nHPV vaccines are safe and effective. All preteens sh ould receive the three dose series of HPV vaccine at age 11 or 12 years. T een boys and girls who did not get the vaccine when they were younger shou ld get it now. Young women can get HPV vaccine through age 26\, and young men can get vaccinated through age 21.\n\nFindings from a recent survey co nducted by the University of Hawaii Cancer Center and John A. Burns School of Medicine validated the important role of both physicians and parents i n getting our keiki vaccinated. Join us and spread the word to your family and friends. HPV vaccination is cancer prevention.\n\nThis event is spons ored by the Hawaii Immunization Coalition and powered by Tugg. It is made possible through generous donations from the following organizations:\n· Hawaii Department of Health Comprehensive Cancer Control Program\n· Honol ulu County Committee on the Status of Women LOCATION:Consolidated Theatres Kahala 8\, 4211 Waialae Avenue\, Honolulu\,\ , HI\, 96816\, United States GEO:21.2773994;-157.78648599999997 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=4211 Waialae Avenue\, Honol ulu\,\, HI\, 96816\, United States;X-APPLE-RADIUS=100;X-TITLE=Consolidated Theatres Kahala 8:geo:21.2773994,-157.78648599999997 END:VEVENT BEGIN:VEVENT UID:41@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151021T120000 DTEND;TZID=Pacific/Honolulu:20151021T130000 DTSTAMP:20151021T184109Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- thesis-defense-vanda-koko-title-high-avidity-antibodies-to-var2csa-are-the y-associated-with-protection-from-placental-malaria-in-a-low-transmission- setting SUMMARY:Tropical Medicine MS Thesis Defense by Vanda Koko\, Title: High Avi dity Antibodies to VAR2CSA - Are They Associated with Protection from Plac ental Malaria in a Low Transmission Setting? DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:0,0 END:VEVENT BEGIN:VEVENT UID:39@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151009T113000 DTEND;TZID=Pacific/Honolulu:20151009T140000 DTSTAMP:20151008T003835Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-asm-student-ch apter-meet-and-greet SUMMARY:Hawaii ASM Student Chapter Meet & Greet DESCRIPTION:Learn about the Hawaii Branch of the American Society of Microb iology and the HPV Vaccination Film: Someone You Love: the HPV Epidemic.\n \nPick up a free malasada to go!\n\nHawaii ASM Student Chapter Blog\n\n&nb sp\;\n\n LOCATION:University of Hawaii at Manoa\, Campus Center 2nd Floor\, 2444 Dol e St.\, Honolulu\, HI\, 96822\, United States GEO:21.2991857;-157.81719780000003 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=2444 Dole St.\, Honolulu\, HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=University of Hawaii at Manoa\, Campus Center 2nd Floor:geo:21.2991857,-157.81719780000003 END:VEVENT BEGIN:VEVENT UID:38@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20151007T000000 DTEND;TZID=Pacific/Honolulu:20151007T130000 DTSTAMP:20151005T211151Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-kenji-obad ia-tropical-medicine-phd-student-flipping-the-switch-to-accurately-diagnos e-malaria-a-comparison-of-clinical-diagnosis-rapid-diagnostic-test-rdt-mic roscopy-and-pcr-in-the SUMMARY:Seminar by Kenji Obadia\, Tropical Medicine PhD Student: "Flipping the Switch to Accurately Diagnose Malaria: A Comparison of Clinical Diagno sis\, Rapid Diagnostic Test (RDT)\, Microscopy and PCR in the Diagnosis of Malaria in Cameroon" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:36@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150916T120000 DTEND;TZID=Pacific/Honolulu:20150916T130000 DTSTAMP:20160101T020339Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-kae-pus ic-univ-of-chicago-neuroimmune-signaling-of-environmental-enrichment-role- of-exosomes-in-remyelination SUMMARY:Seminar by Dr. Kae Pusic\, Univ of Chicago: "Neuroimmune Signaling of Environmental Enrichment: Role of Exosomes in Remyelination" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:35@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150826T120000 DTEND;TZID=Pacific/Honolulu:20150826T130000 DTSTAMP:20150825T210456Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-sem inar-someone-you-love-the-hpv-epidemic SUMMARY:Tropical Medicine Seminar: "Someone You Love: The HPV Epidemic" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:34@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150814T121500 DTEND;TZID=Pacific/Honolulu:20150814T131500 DTSTAMP:20150811T011708Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-james-k elley-frequency-and-characterization-of-cd14-monocytes-and-macrophage-subs ets-in-children-with-dengue-fever-in-bangkok-thailand SUMMARY:Seminar by Dr. James Kelley: Frequency and Characterization of CD14 + Monocytes and Macrophage Subsets in Children with Dengue Fever in Bangko k\, Thailand DESCRIPTION:COBRE TMMMP Seminar James Kelley 081415 LOCATION:JABSOM Medical Education Bldg.\, Rm 314\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 314:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:33@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150813T173000 DTEND;TZID=Pacific/Honolulu:20150813T210000 DTSTAMP:20150807T214853Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2nd-annual-e-hooulu-h aumana-presentation-by-2015-mhirt-students SUMMARY:2nd Annual E Ho'oulu Haumana Presentation by 2015 MHIRT Students DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:32@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150708T103000 DTEND;TZID=Pacific/Honolulu:20150708T113000 DTSTAMP:20150706T200622Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=2015-alicata-award-pr esentation-to-kelsey-roe-phd SUMMARY:2015 Alicata Award Presentation to Kelsey Roe\, PhD DESCRIPTION:Please join us at 10:30 AM on Wednesday\, July 8 to present the 2015 Alicata Award to Dr. Kelsey Roe who recently completed her PhD degre e in our program. Light refreshments will be served.\n\nLet's congratulate Kelsey on her achievements and wish her the best as she moves on to a pos tdoctoral position at the University of Washington in Seattle. LOCATION:JABSOM BioScience Bldg. Rm 320\, 651 Ilalo St.\, Honolulu\,\, HI\, United States GEO:21.2966192;-157.8636922 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm 320:geo:21.2966192,-157.8636922 END:VEVENT BEGIN:VEVENT UID:31@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150630T120000 DTEND;TZID=Pacific/Honolulu:20150630T120000 DTSTAMP:20150627T011037Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=brooks-mitchell-ms-th esis-defense-the-association-of-peripheral-blood-monocytes-to-cardiometabo lic-complications-in-hiv-infected-individuals-on-stable-antiretroviral-the rapy SUMMARY:Brooks Mitchell MS Thesis Defense: "The association of peripheral b lood monocytes to cardiometabolic complications in HIV-infected individual s on stable antiretroviral therapy" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:28@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150522T000000 DTEND;TZID=Pacific/Honolulu:20150522T130000 DTSTAMP:20150430T231357Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-presentation- by-tung-t-hoang-on-the-transitive-of-burkholderia-pseudomallei-reveals-nov el-mechanisms-and-regulation-of-virulence SUMMARY:Seminar Presentation by Tung T. Hoang on "The 'Transitome' of Burkh olderia pseudomallei Reveals Novel Mechanisms and Regulation of Virulence" DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:30@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150520T100000 DTEND;TZID=Pacific/Honolulu:20150520T110000 DTSTAMP:20150507T001150Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=kelsey-roe-dissertati on-defense-impact-of-triggering-receptor-expressed-on-myeloid-cells-1-trem -1-on-anti-viral-immunity-to-west-nile-virus SUMMARY:Kelsey Roe Dissertation Defense: "Impact of triggering receptor exp ressed on myeloid cells 1 (TREM-1) on anti-viral immunity to West Nile vir us" DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:29@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150506T000000 DTEND;TZID=Pacific/Honolulu:20150506T130000 DTSTAMP:20150506T210846Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-ms- student-priscilla-seabourn-presents-host-factors-that-drive-reactivation-a nd-rearrangement-of-polyomavirus-jc SUMMARY:Tropical Medicine MS Student Priscilla Seabourn presents "Host fact ors that drive reactivation and rearrangement of polyomavirus\, JC DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:27@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150429T120000 DTEND;TZID=Pacific/Honolulu:20150429T130000 DTSTAMP:20150428T213742Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ms-student-micah-tepo ra-presents-respiratory-syncytial-virus-rsv-and-native-virus-like-particle s-as-a-vaccine-strategy SUMMARY:MS Student Micah Tepora presents "Respiratory Syncytial Virus (RSV) and Native Virus-Like Particles as a Vaccine Strategy DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:25@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150425T081500 DTEND;TZID=Pacific/Honolulu:20150425T160000 DTSTAMP:20150325T210513Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=asm-spring-meeting-ab stract-deadline SUMMARY:ASM Spring Meeting DESCRIPTION:\n\n \;\n\nDownload registration form here\n\nDownload abst ract submission form here LOCATION:Treetops Restaurant\, 3737 Manoa Rd.\, Honolulu\,\, HI\, 96822\, U nited States GEO:21.3293809;-157.8018682 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=3737 Manoa Rd.\, Honolulu\, \, HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=Treetops Restaura nt:geo:21.3293809,-157.8018682 END:VEVENT BEGIN:VEVENT UID:26@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu;VALUE=DATE:20150415 DTEND;TZID=Pacific/Honolulu;VALUE=DATE:20150418 DTSTAMP:20150325T212003Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=jabsom-biomedical-sci ences-health-disparities-symposium SUMMARY:JABSOM Biomedical Sciences & Health Disparities Symposium DESCRIPTION:JABSOM Biomedical Sciences &\; Health Disparities Symposium\ n\n LOCATION:Sullivan Conference Center\, UH Cancer Center\, 651 Ilalo St.\, Ho nolulu\,\, HI\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=Sullivan Conference Center \, UH Cancer Center:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:24@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150401T120000 DTEND;TZID=Pacific/Honolulu:20150401T130000 DTSTAMP:20150325T203518Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=tropical-medicine-phd -student-danielle-clements-presents-malaria-vaccine-design-based-on-pfmsp1 -and-nanoparticle-delivery SUMMARY:Tropical Medicine PhD Student Danielle Clements presents "Malaria V accine Design Based on PfMSP1 and Nanoparticle Delivery" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:23@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150318T120000 DTEND;TZID=Pacific/Honolulu:20150318T130000 DTSTAMP:20150317T012631Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-phd-studen t-kelsey-roe-the-search-for-innate-immune-signatures-that-forecast-immunog enicity-or-disease SUMMARY:Seminar by Tropical Medicine PhD Student Kelsey Roe: The search for innate immune signatures that forecast immunogenicity or disease DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:21@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150316T000000 DTEND;TZID=Pacific/Honolulu:20150316T130000 DTSTAMP:20150303T192119Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-by-dr-richard-neher-max-planck-institute-for-developmental-biolo gy-rna-virus-evolution-tracing-quasi-species-of-hiv-1-and-predicting-influ enza-viruses SUMMARY:COBRE/Tropical Medicine Seminar by Dr. Richard Neher\, Max Planck I nstitute for Developmental Biology: RNA Virus Evolution - Tracing Quasi-Sp ecies of HIV-1 and Predicting Influenza Viruses DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:22@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150311T120000 DTEND;TZID=Pacific/Honolulu:20150311T130000 DTSTAMP:20150303T233122Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-timothy -liedl-on-dna-self-assembly-for-biomedical-applications SUMMARY:Seminar by Dr. Timothy Liedl on "DNA self-assembly for biomedical a pplications" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:20@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150128T000000 DTEND;TZID=Pacific/Honolulu:20150128T130000 DTSTAMP:20150126T214323Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-dr-robert-mah oney-president-rtm-associates-presents-introduction-of-dengue-vaccines SUMMARY:Seminar: Dr. Richard Mahoney\, President\, RTM Associates presents "Introduction of Dengue Vaccines" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:19@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150121T120000 DTEND;TZID=Pacific/Honolulu:20150121T130000 DTSTAMP:20150115T013406Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-anna-babakhan yan-phd-to-speak-on-the-influence-of-hiv-on-immunity-to-malaria-in-cameroo nian-women-and-neonates SUMMARY:Seminar: Anna Babakhanyan\, PhD to speak on "The Influence of HIV o n Immunity to Malaria in Cameroonian Women and Neonates" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:17@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150120T120000 DTEND;TZID=Pacific/Honolulu:20150120T130000 DTSTAMP:20150107T011136Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=special-seminar-by-dr -terry-bishop-niddhnih-program-director-navigating-the-nih-finding-landmar ks-necessary-to-acquire-federal-government-grants SUMMARY:Special Seminar by Dr. Terry Bishop\, NIDDH/NIH Program Director: " Navigating the NIH: Finding landmarks necessary to acquire federal governm ent grants" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:18@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150114T120000 DTEND;TZID=Pacific/Honolulu:20150114T130000 DTSTAMP:20150107T232853Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-sladjan a-prisic-uh-dept-of-microbiology-alternative-lifestyle-of-mycobacterium-tu berculosis SUMMARY:Seminar by Dr. Sladjana Prisic\, UH Dept. of Microbiology: "ALTerna tive lifestyle of Mycobacterium tuberculosis" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg.\, Rm 301\, 651 Ilalo St.\, Honolulu \,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg.\, Rm 301:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:16@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20150107T120000 DTEND;TZID=Pacific/Honolulu:20150107T130000 DTSTAMP:20160405T212047Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-by-dr-beth-an n-coller-merck-co-inc-clinical-and-preclinical-development-of-a-recombinan t-subunit-vaccine-for-dengue SUMMARY:Seminar by Dr. Beth-Ann Coller\, Merck & Co.\, Inc.: Clinical and P reclinical Development of a Recombinant Subunit Vaccine for Dengue DESCRIPTION: CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:14@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141216T140000 DTEND;TZID=Pacific/Honolulu:20141216T150000 DTSTAMP:20141211T192306Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ms-thesis-defense-jac ob-nelson-presents-novel-antiviral-and-histone-deacetylase-inhibitors-incr ease-survival-of-wnv-infected-mice SUMMARY:MS Thesis Defense: Jacob Nelson presents "Novel Antiviral and Histo ne Deacetylase Inhibitors Increase Survival of WNV Infected Mice" DESCRIPTION: LOCATION:JABSOM BioScience Bldg. Rm. 320N\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM BioScience Bldg. Rm . 320N:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:15@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141212T083000 DTEND;TZID=Pacific/Honolulu:20141212T083000 DTSTAMP:20141212T025203Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=honors-programundergr aduate-research-opportunities-program-urop-fall-forum SUMMARY:Honors Program/Undergraduate Research Opportunities Program (UROP) Fall Forum DESCRIPTION:2014 Fall Forum Program\n\nOral Presentations:\n\n10:15 AM: Mic helle Fischer\, Rm. E204\n\n11:00 AM: Kendrick Go\, Rm. E204\n\n11:15 AM: Jessi Tsukuyama\, E201\n\n11:30 AM: Shayne Rasay\, E202 LOCATION:Shidler College of Business\, 2404 Maile Way\, Honolulu\,\, HI\, 9 6822\, United States GEO:21.3017148;-157.8202175 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=2404 Maile Way\, Honolulu\, \, HI\, 96822\, United States;X-APPLE-RADIUS=100;X-TITLE=Shidler College o f Business:geo:21.3017148,-157.8202175 END:VEVENT BEGIN:VEVENT UID:13@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141210T120000 DTEND;TZID=Pacific/Honolulu:20141210T130000 DTSTAMP:20141208T220203Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-mahdi-belcaid -presents-the-next-next-generation-sequencing-empowering-a-new-era-of-biol ogy SUMMARY:Seminar: Mahdi Belcaid Presents "The Next-(Next)-Generation Sequenc ing: Empowering a New Era of Biology" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:11@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141126T120000 DTEND;TZID=Pacific/Honolulu:20141126T130000 DTSTAMP:20141121T014354Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-brooks-mitche ll-presents-the-role-of-monocytes-in-hiv-associated-comorbidities SUMMARY:Seminar: Brooks Mitchell presents "The Role of Monocytes in HIV-ass ociated Comorbidities" DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:12@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141124T173000 DTEND;TZID=Pacific/Honolulu:20141124T190000 DTSTAMP:20141125T023713Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=ebola-preparedness-sy mposium SUMMARY:Ebola Preparedness Symposium DESCRIPTION:The John A. Burns School of Medicine and its community partners in health are assembling a panel of Hawai`i's top experts in Tropical Med icine and Infectious Disease\, to discuss the continuing response to the c risis in West Africa. We hope you will join us for information from:\n\n S tate Health Director Linda Rosen\, MD\n State Epidemiologist Sarah Park\, MD\n State Senate Health Chair Josh Green\, MD\n Public Health Security Sp ecialist James Campbell\, MD (Asia Pacific Center for Security Studies)\n Emergency Services Director Toby Clairmont\, Healthcare Association of Haw ai`i\n CDC Quarantine Medical Officer Tai-Ho Chen\, MD\n UH Medical Profes sor F. DeWolfe Miller\, PhD\n\nWebsite:\nhttps://www.smore.com/bvcp9-forum -experts-in-ebola-response?ref=email-content#w-8756115051 LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:10@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141119T120000 DTEND;TZID=Pacific/Honolulu:20141119T120000 DTSTAMP:20141113T011347Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=cobretropical-medicin e-seminar-bacteria-as-drivers-of-animal-evolution SUMMARY:COBRE/Tropical Medicine Seminar by Dr. Rosanna Algado: Bacteria as Drivers of Animal Evolution DESCRIPTION: LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:9@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141112T120000 DTEND;TZID=Pacific/Honolulu:20141112T130000 DTSTAMP:20141112T234044Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-vanda-koko-an d-elise-penvadga-ngati-present-defining-immunity-to-placental-malaria-work -in-progress SUMMARY:Seminar: Vanda Koko and Elise Penvadga Ngati present "Defining Immu nity to Placental Malaria: Work in Progress" DESCRIPTION:Department of Tropical Medicine\, Medical Microbiology and Phar macology\n\nSEMINAR\nTRMD 690\n\nDefining Immunity to Placental Malaria:\n Work in Progress\nPart II\n\nVanda Koko and Elise Penvadga Ngati\nGraduate Students\nDepartment of Tropical Medicine\, Medical Microbiology and Phar macology\n\nWednesday\nNovember 12\, 2014 @ 12:00 Noon\n\nMedical Educatio n Building\nAuditorium Room 315\nJohn A. Burns School of Medicine\n651 Ila lo Street\, Honolulu\, Hawaii 96813\n\nFor further information\, call DeWo lfe Miller (692-1605)\n\n \; LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:8@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141105T120000 DTEND;TZID=Pacific/Honolulu:20141105T130000 DTSTAMP:20141121T014455Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-f-dewolfe-mil ler-presents-the-epidemiology-of-a-blood-borne-pathogen SUMMARY:Seminar: F. DeWolfe Miller presents: "The epidemiology of a blood-b orne pathogen" DESCRIPTION:Department of Tropical Medicine\, Medical Microbiology and Phar macology\nSEMINAR\nTRMD 690\nHCV\nThe epidemiology of a blood-borne pathog en\nF. DeWolfe Miller\, Ph.D.\nProfessor\nDepartment of Tropical Medicine\ , Medical Microbiology and Pharmacology\nWednesday\nNovember 5\, 2014 @ 12 :00 Noon\nMedical Education Building\nAuditorium Room 315\nJohn A. Burns S chool of Medicine\n651 Ilalo Street\, Honolulu\, Hawaii 96813\nFor further information\, call DeWolfe Miller (692-1605) LOCATION:John A Burns School of Medicine\, Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=John A Burns Schoo l of Medicine\, Medical Education Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:7@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141029T000000 DTEND;TZID=Pacific/Honolulu:20141029T000000 DTSTAMP:20141121T014252Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-jourdan-posne r-presents-the-effect-of-prr-ligands-on-b-cell-subsets-important-to-the-ge rminal-center-reaction SUMMARY:Seminar: Jourdan Posner presents "The effect of PRR ligands on B ce ll subsets important to the germinal center reaction" DESCRIPTION:Department of Tropical Medicine\, Medical Microbiology and Phar macology\nSEMINAR TRMD 690\nThe effect of PRR ligands on B cell subsets im portant to the germinal center reaction\n\nJourdan PosnerPhD Graduate Stud entDepartment of Tropical Medicine\, Medical Microbiology and Pharmacology \nWednesday October 29\, 2014 @ 12:00 Noon\nMedical Education Building Aud itorium\, Room 315\nJohn A. Burns School of Medicine 651 Ilalo Street\, Ho nolulu\, Hawaii 96813\nFor further information\, call DeWolfe Miller (692- 1605) CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:6@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141022T000000 DTEND;TZID=Pacific/Honolulu:20141022T130000 DTSTAMP:20141121T014244Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-effects-of-vi ral-encephalitis-on-glutamate-signaling SUMMARY:Seminar: Effects of Viral Encephalitis on Glutamate Signaling DESCRIPTION:Tropical Medicine Seminar\, TRMD 690\nSpeaker: Jacob Nelson\, T ropical Medicine Graduate Student LOCATION:John A Burns School of Medicine\, Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\,\, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=John A Burns Schoo l of Medicine\, Medical Education Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:2@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141021T180000 DTEND;TZID=Pacific/Honolulu:20141021T210000 DTSTAMP:20141121T014237Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=hawaii-asm-fall-meeti ng SUMMARY:UPDATE: Hawaii ASM Fall Meeting DESCRIPTION:Guest Speaker: Dr. Karen Frank\nDepartment of Laboratory Medici ne National Institutes of Health\nTitle:  MALDI-TOF Mass Spectrometry for Microbial Identification\n\nASM Meeting Agenda:\nArrival: 6:00-6:30 PM Di nner: 6:30-7:30 PM Lecture: 7:45-8:45 PM Business Mtg.: 8:45-9:00 PM\nPlea se RSVP by October 14\, 2014\n\nNEW: HI-ASM members also invited to attend ASCLS workshop on Ebola virus at 3:30-5:00 PM\, immediately before ASM m eeting at the conference center.\nTitle: Ebolavirus: River Menace\nSpeaker :\nJames T. Griffith\, Ph.D.\, CLS (NCA)Chancellor Professor &\; Gradua te Program Director\, University of Massachusetts A little-known river vi rus has become a global concern in less than a year. This session will cov er historic\, geographic and epidemiologic aspects of the current and prev ious outbreaks. Attention will be given to diagnostics\, specimen transpor t and the status of treatment options. Future implications will also be co vered.\n\nObjectives:\n\n Describe the historic and geographic origins of the Ebolavirus\n Discuss the signs &\; symptoms\, early intervention an d treatment options\n Describe current diagnostic and specimen management technology\n\nDownload registration form and meeting announcement:\nASM Fa ll 2014 Reg Form\nASM Fall Announcement LOCATION:Ko'olau Conference Center\, 45-550 Kionaole Rd\, Kaneohe\, HI\, 96 744\, United States GEO:21.3744597;-157.7937998 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=45-550 Kionaole Rd\, Kaneoh e\, HI\, 96744\, United States;X-APPLE-RADIUS=100;X-TITLE=Ko'olau Conferen ce Center:geo:21.3744597,-157.7937998 END:VEVENT BEGIN:VEVENT UID:5@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141008T120000 DTEND;TZID=Pacific/Honolulu:20141008T130000 DTSTAMP:20141121T014421Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-dr-mukesh-kum ar-presents-neuropathogenesis-of-west-nile-virus-infection SUMMARY:Seminar: Dr. Mukesh Kumar presents "Neuropathogenesis of West Nile virus infection" DESCRIPTION: \;\n\n LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:4@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20141001T120000 DTEND;TZID=Pacific/Honolulu:20141001T130000 DTSTAMP:20141121T014230Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=seminar-defining-immu nity-to-placental-malaria-work-in-progress SUMMARY:Seminar: Defining Immunity to Placental Malaria - Work in Progress DESCRIPTION:TRMD 690 Seminar\nSpeakers:\nElise Penvaga Ngati\nVanda Koko\nT ropical Medicine Graduate Students\n\nFor further information\, call DeWol fe Miller\, 692-1605 CATEGORIES:Seminar LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:3@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20140917T000000 DTEND;TZID=Pacific/Honolulu:20140917T133000 DTSTAMP:20141112T234252Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=research-colloquium-e bola-what-do-we-know SUMMARY:Research Colloquium: Ebola - What do we know? DESCRIPTION:Ebola Virus Disease\nAxel T. Lehrer\, Ph.D. Assistant Professor Department of Tropical Medicine\, Medical Microbiology and Pharmacology J ohn A. Burns School of Medicine University of Hawaii at Manoa\n\nPersonal Perspectives on My Work in Liberia during the time of Ebola\nJohn M. Beres tecky\, Ph.D. Professor of Microbiology Kapi‘olani Community College\n\n Hope for the Best\, Plan for the Worst\nErlaine F. Bello\, M.D. Associate Professor Department of Medicine John A. Burns School of Medicine Universi ty of Hawaii at Manoa\n\nWednesday\, September 17\, 2014\, 12:00 – 1:30 p.m.\nJohn A. Burns School of Medicine\, Kaka‘ako\nMedical Education Bui lding Auditorium (Room 315)\nFor further information\, contact Dr. Vivek R . Nerurkar\, (808) 692-1668 LOCATION:John A. Burns School of Medicine\, 651 Ilalo St.\, Honolulu\,\, HI \, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, United States;X-APPLE-RADIUS=100;X-TITLE=John A. Burns School of Me dicine:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VEVENT UID:1@manoa.hawaii.edu DTSTART;TZID=Pacific/Honolulu:20140822T180000 DTEND;TZID=Pacific/Honolulu:20140822T210000 DTSTAMP:20140822T011438Z URL:https://manoa.hawaii.edu/tropicalmedicine/?event=the-1st-annual-e-hoou lu-haumana-presentation-by-the-2014-mhirt-students SUMMARY:First Annual E Ho‘oulu Haumāna Presentation by 2014 MHIRT Studen ts DESCRIPTION:\nThe John A. Burns School of Medicine\nUniversity of Hawaii\nM inority Health and Health Disparities\nInternational Research Training (MH IRT)\nProgram cordially invites you to\n \nThe 1st Annual E Ho‘oulu Hau māna Presentation\nby the 2014 MHIRT Students\nFriday\, August 22\, 2014\ n6:00 – 9:00 P.M.\nMedical Education Building Auditorium 315\nJohn A. Bu rns School of Medicine\n651 Ilalo St. Honolulu\, HI 96813\n\n \nE Ho‘ou lu Haumāna essentially means “growing students.”\nThe MHIRT students will present their scientific research findings\nand cultural experiences in Thailand and Cameroon.\n \nPlease arrive at 6:00 P.M. to meet the stud ents.\nLight pupus and refreshments will be served.\n\nStudent presentatio ns will start promptly at 6:30 P.M.\n\n \nParking is available at Lot C a cross the Biosciences Building\nand along Ilalo St.\n \nPlease RSVP by Au gust 11\, 2014 to:\nLaarni Sumibcay (email: sumibcay@hawaii.edu)\n\nIf yo u require special assistance\, please call 692-1652.\n \nThe UH MHIRT Pro gram grant is awarded to\nDr. Vivek R. Nerurkar and Dr. Diane Wallace Tayl or\nby the National Institute on Minority Health and Health Disparities\,\ n\n\n\nNational Institutes of Health grant number T37MD008636-01\n \n\n LOCATION:JABSOM Medical Education Bldg. Rm 315\, 651 Ilalo St.\, Honolulu\, \, HI\, 96813\, United States GEO:21.2965278;-157.8637996 X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=651 Ilalo St.\, Honolulu\,\ , HI\, 96813\, United States;X-APPLE-RADIUS=100;X-TITLE=JABSOM Medical Edu cation Bldg. Rm 315:geo:21.2965278,-157.8637996 END:VEVENT BEGIN:VTIMEZONE TZID:Pacific/Honolulu X-LIC-LOCATION:Pacific/Honolulu BEGIN:STANDARD DTSTART:20130822T180000 TZOFFSETFROM:-1000 TZOFFSETTO:-1000 TZNAME:HST END:STANDARD END:VTIMEZONE END:VCALENDAR