Home / Health Sciences & Social Welfare / $11M in new NIH funding for groundbreaking work in reproductive research
green lamb
UH Manoa's Institute for Biogenesis Research developed new, more efficient methods to produce transgenic animals such as this lamb, which glows green under a black light.

$11M in new NIH funding for groundbreaking work in reproductive research

The Institute for Biogenesis Research at the John A. Burns School of Medicine has been awarded $10.8 million from the National Institutes of Health to continue its groundbreaking work in reproductive and developmental biomedical research.

The Institute laid the scientific foundation for human in vitro fertilization under founder Dr. Ryuzo Yanagimachi, whose assisted reproductive methods are still being used around the world to help infertile couples have children. The Institute also cloned the world’s first mouse and has developed new, more efficient methods to produce transgenic mice, rabbits, lambs and pigs. The animals glow green under black light, demonstrating a more-efficient genetic manipulation technique developed in Hawai`i. That technique may lead to new and competitively efficient ways to produce medicines.

Institute scientists competed with researchers all over the U.S. to win this phase-two “Centers of Biomedical Research Excellence award. The new grant brings the Institute’s total research dollar awards to nearly $40 million dollars in the past 15 years.

“This is a very good measurement of success for the Institute,” said Dr. Steven Ward, Director of the Institute for Biogenesis Research. “Any research institute is measured by its notoriety worldwide, which we’ve also had recently. It is measured by the success of its faculty members, and by the amount of federal dollars it can bring in. So we’re very pleased that we were just awarded this second $11 million grant.”

Dr. Ward said Hawai`i residents benefit from the research award, because nearly all of the funds are spent here in the Islands.

“The $10.8 million grant that we just brought in, 80% of that, or $8.7 million of that goes directly into the Hawai‘i economy,” said Dr. Ward.

Research grants awarded to the medical school also help support operations of the University of Hawai`i as a whole. That is because half of all research money the medical school brings in goes to UH Mānoa and the UH System for them to spend in Hawai`i.

The Institute for Biogenesis Research has 14 faculty members.

GRANT: National Institute of General Medical Sciences (NIGMS, Grant No. 2P20GM103457-06A1)

Source:  John A. Burns School of Medicine news release