(1 1-hr Lec, 2 3-hr Lab) First course in a two-semester major open-ended design experience for senior students in biological engineering, with heavy emphasis on teaching written/oral engineering communication. Design process; project management; methodology; modeling; optimization; engineering economics. A-F only. Pre: (350/350L, 373, CEE 320 (or concurrent) or ME 322 (or concurrent), ME 311, ECE 211) with a minimum grade of C-; or consent.