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Tag Archives: Institute for Biogenesis Research

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Two Y genes can replace the entire Y chromosome for assisted reproduction in mice

Mother mouse with litter

The Y chromosome is a symbol of maleness, present only in males and encoding genes important for male reproduction. But live mouse progeny can be generated with assisted reproduction using germ cells from males with the Y chromosome contribution limited to only two genes: the testis determinant factor Sry and the spermatogonial proliferation factor Eif2s3y. “Does this mean that the ... Read More »

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