“Together we can age without HIV”
September 18th is National HIV/AIDS and Aging Awareness Day
The aging population of HIV-infected individuals on antiretroviral therapy (ART) is an emerging model for studying premature aging. People living with HIV/AIDS (PLWHA) may have several co-morbidities (illnesses) that can complicate the aging process and increase vulnerability to aging. This leads to a decline in body function and potential, which is clinically described as frailty. We have seen both physiological and cognitive declines in PLWHA, and we offer clinical services and HIV research for our patients to live longer, healthier lives.
The Clint Spencer Clinic is proud to provide medical services for PLWHA, including older adults. We are an HIV clinic in Hawaiʻi with services that include Oʻahu, Maui, and the Big Island. We collaborate with other organizations to provide a wide range of services.
The Hawaii Center for AIDS also participates in clinical studies evaluating aging in people with HIV/AIDS. We are currently running studies concerning frailty, Alzheimer’s, and other cognitive conditions.
JABSOM covers our new collaboration with Neuraltus Pharamceuticals: a Phase 1b study of NP001 in patients with mild-to-moderate Alzheimer’s Disease. Check it out below:
“Given the key role inflammatory monocytes and macrophages may play in the progression of Alzheimer’s disease, researching immune regulators – like NP001 – is critical to understanding more about this serious and complex disease.” – Dr. Beau Nakamoto
“This is the first clinical study of NP001 in Alzheimer’s disease and we look forward to examining the results to see whether the compound impacts inflammation levels in this patient population.” – Rich Casey, Neuraltus Pharmaceutals CEO
“This trial wouldn’t be happening in Hawaiʻi without the RMATRIX (Multidisciplinary And Translational Research Infrastructure Expansion) Program at JABSOM, which supports the mentoring of junior scientists and the professional relationships forged through scientific collaboration.” – Dr. Cecilia Shikuma
UH Medical School: Phase 1b study announced of NP001 in patients with mild-to-moderate Alzheimer’s Disease
HICFA shows support for Gregory House’s Fundraiser Event on Sept 9, 2017
HICFA’s 5-digit code number #: 789-24
Give Aloha, Foodland’s Annual Community Matching Gifts Program begins next Friday, September 1, and we were chosen to participate!
Customers are encouraged to make a donation at checkout to their favorite Hawaiʻi non-profit organization including HICFA. This year, Foodland and the Western Union Foundation will match each donation with more than $300,000 for all organizations combined.
- During September, Maika`i members are invited to make donations up to $249 to their favorite participating Hawaii non-profit organizations at checkout.
- Also customers who shop using their own reusable bag have the option of receiving a 5¢ credit or 3 HawaiianMiles for each reusable bag they bring and use. During September, customers may choose to donate their 5¢ bag credit to the Give Aloha matching gifts fund!
Thank you for supporting HICFA!
For more information, see Foodland’s website at: https://www.foodland.com/blog/give-aloha-2017
Both Glen Chew and Eleanore Chuang in Drs. Ndhlovu and Shiramizu’s lab have been awarded the ‘Joseph E. Alicata Award’ by the Department of Tropical Medicine, Medical Microbiology and Pharmacology.
The stated purposes of this award are: (1) to encourage the study of Tropical Medicine and Infectious Disease; and (2) to reward outstanding scholastic achievement in Tropical Medicine and Infectious Disease.
For more information, see the Tropical Medicine website at: http://manoa.hawaii.edu/tropicalmedicine/?page_id=366#Alicata
On Monday, May 1, 2017, at 4 p.m. in the Orvis Auditorium, UH Mānoa recognized its finest faculty, staff and students with teaching, research and service awards. The ceremony was free and open to the public. http://manoa.hawaii.edu/chancellor/awards/
Glen M. Chew
Glen Chew has a high affinity for science and technology and brings novel constructive ideas to his PhD research project in the Department of Tropical Medicine, Medical Microbiology and Pharmacology at the John A. Burns School of Medicine. His research focuses on understanding mechanisms driving immune dysfunction during chronic viral infections. As a PhD candidate, he has published a first-authored, peer-reviewed scientific manuscript on his research and also contributed to nine co-authored publications. He received the 2016 Koenig Award in Medicine from the ARCS foundation (Honolulu Chapter) and the 2015 and 2016 Chancellor Virginia S. Hinshaw Biomedical Research Scholarships for his research. Chew also presented his research at the Conference on Retroviruses and Opportunistic Infections in 2014 and 2017 and at the International AIDS Society in 2015. His research will lead to ways to harness the immune system to prevent, control or eliminate HIV infection and optimize quality of life outcomes.
HICFA was well represented at CROI 2017 this year. Among the highlights were:
Congratulations to three members of HICFA, Brooks Mitchell, Glen Chew, and Michelle D’Antoni Brogan on receiving a scholarship to attend the CROI 2017 meeting (Conference on Retroviruses and Opportunistic Infections 2017). They will present their abstracts in Seattle, WA between Feb 13-16, 2017.
Brooks Mitchell, Ph.D. Student
Exhausted T cells and inflammatory Monocytes are linked to Brain Atrophy in HIV
Glen Chew, Ph.D. Student
Metformin Reduces T cell Exhaustion in a Clinical Trial of HIV Infected Adults on Antiretroviral Therapy
Michelle D’Antoni Brogan, Adjunct Instructor, Scientist
1) Cenicriviroc Improves Neurocognition and Reduces Monocyte Activation in Treated HIV
2) Plasma Soluble CD163 Is Suppressed Upon Early ART Initiation In Acute HIV Infection
The Hawaii Center for AIDS joins JABSOM’s Health Fair.
See video below:
Happy Holidays from the Ndhlovu Immunology Lab!