Marla J. Berry  , PhD
Professor and Director, Pacific Biosciences Research CenterSchool of Ocean & Earth Science & Technology (SOEST) – University of Hawai‘i at Mānoa
Work Email: mberry@hawaii.edu
Research Interests
Selenoproteins and selenium metabolism. Roles in neurological disease and metabolic syndrome.
Recent Publications
- Ogawa-Wong AN, Hashimoto AC, Ha H, Pitts MW, Seale LA, Berry MJ. Sexual Dimorphism in the Selenocysteine Lyase Knockout Mouse. Nutrients 2018 Jan. 10(2).
- Gong T, Torres DJ, Berry MJ, Pitts MW. Hypothalamic redox balance and leptin signaling - Emerging role of selenoproteins. Free Radic Biol Med. 2018 Nov 1;127, 172-181. PMC6123311 [IF 6.02]
- Torres DJ, Pitts MW, Hashimoto AC, Berry MJ. Agrp-specific ablation of Scly protects against diet-induced obesity and leptin resistance. 2019. Jul 23;11(7). Pii: E1693. doi: 10.3390/nu11071693. PMC6682868 [IF 4.6]
- Seale LA, Khadka VS, Menor M, Xie G, Watanabe LM, Sasuclark L, Guirguis K, Ha HY, Hashimoto AC, Peplowska K, Tiirikainen M, Jia W, Berry MJ, Deng Y. Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice. 2019 Oct 26;11(11). pii: E2584. PMC6893568.
Recent Grants
- R01 DK47320-24, NIH/NIDDK (Berry MJ, PI) 4/17 – 3/21, Mechanism of selenoprotein synthesis.
- U54 MD007601, NIH/NIMHD (Hedges J, Mokuau N, PIs) 09/17 - 06/22, Ola Hawaii. Goals are to support, strengthen and diversify the basic biomedical, behavioral, clinical and community research workforce and thinkforce engaged in the science of minority health and health disparities.
Bradley (Kai) Fox  , PhD
Aquaculture Extension Specialist and Project and Partner Coordinator, Center for Sustainable Aquaculture and Coastal ResourcesUniversity of Hawaiʻi Sea Grant College Program, School of Ocean and Earth Science and Technology
Work Phone: 808-291-2623 Work Email: bradleyf@hawaii.edu
Research Interests
Current aspects of aquaculture species of importance to community and commercial interests in Hawai‘i and the United States Affiliated Pacific Islands.
Recent Publications
- Ju, Z.Y., S. David, K. Ramm, M. Steck, F. Soller, and B.K. Fox (2017). Effects of microalgae-added diets on growth performance and meat composition of tilapia (Oreochromis mossambicus). Aquaculture Research 48:5053-5061.
- B.K. Fox, K.D. Gorospe, R.D. Haverkort-Yeh, and M.A.J. Rivera (2013). It’s a snap! An Inquiry- Based, Snapping Shrimp Bioacoustics Activity. The American Biology Teacher 75(7): 470-475.
- Gorospe, K.D., B.K. Fox, R.D. Haverkort-Yeh, C.S. Tamaru, and M.A.J. Rivera (2013). Engaging Students in the Pacific and Beyond Using an Inquiry-Based Lesson in Ocean Acidification. Journal of Geoscience Education 61: 396-404.
- Soto, E., K. McGovern-Hopkins, R. Klinger-Bowen, B.K. Fox, J. Brock, N. Antonio, Z. van der Waal, S. Rushton, A. Mill, and C.S. Tamaru (2013). Prevalence of Francisella noatunensis subsp. orentalis in Cultured Tilapia on the Island of O‘ahu, Hawai‘i. Journal of Aquatic Animal Health 25(2): 104-109.
Recent Grants
- Strengthening Hawaii's Seafood Workforce and Educational Opportunities for the Next Generation of Young Fishers and Aquaculturists. PI: Cherie Kauahi, Hawai‘i Sea Grant. Co-Is: Darren K.Okimoto, Bradley Fox, Eileen Peppard, Hawai‘i Sea Grant; Maria Haws, University of Hawai‘iat Hilo. $100,000. Sept. 1, 2021-Feb. 28, 2022.
- Roadmap to Food for Loko I‘a (Hawaiian Fishponds) - Pua (Young Fish) Stocking. PI: Cherie Kauahi. Co-Is: Darren K. Okimoto, Bradley Fox, Hawai‘i Sea Grant. $15,000. Sept. 1, 2021-Feb. 28, 2022.
- Addressing COVID-19 Impacts to Local Food Security Through Aquaculture of Native Hawaiian Marine Finfish and Seaweed. PI: Bradley Fox, Hawai‘i Sea Grant. Co-Is: Cherie Kauahi, Darren K. Okimoto, Darren T. Lerner, Elizabeth Lenz, Hawai‘i Sea Grant; Maria Haws, University of Hawai‘i at Hilo. $200,000. Sept. 1, 2021-Aug. 31, 2023.
- Establishing a Supply and Training Program for Aquaculture Production of Hawaiian Sea Cucumber. PI: David Anderson, Kauai Sea Farm. Co-Is: Cherie Kauahi, Bradley Fox, Darren K. Okimoto, Darren T. Lerner, Hawaiʻi Sea Grant; Anthony Mau, Kualoa Ranch Hawaiʻi; Maria Haws, University of Hawai‘i at Hilo. $299,154. Sept. 1, 2021-Aug.31, 2023.
Current Graduate Students
- Andrew Bohringer (MS, Tropical Plant and Soil Sciences), Aquaponic cultivation of taro
- Jonathan Rosen (MS, Marine Biology), Temperature stress on reef fishes
- Seaenna Correa-Garcia (MS, Marine Biology), Native seaweed cultivation
- Tyler Goodearly (PhD, Nutritional Sciences), Environmental physiology of sea cucumbers
- Reilly Merlo (MS, Animal Science), Effects of salinity on fish nutrition
- Tharindu Malintha (PhD, Nutritional Sciences), Environmental regulation of transcription factors in fish
Lucia A. Seale  , MS, PhD
Associate Research ProfessorPacific Biosciences Research Center, School of Ocean & Earth Science & Technology (SOEST)
Work Email: lseale@hawaii.edu
Research Interests
The metabolism of the micronutrient selenium and its impact in lipid biology, adipocyte physiology and obesity development.
Recent Publications
- - Ralston NVC, Raymond LJ, Gilman CL, Soon R, Seale LA, Berry MJ. (2024) Maternal seafood consumption is associated with improved selenium status: Implications for child health. Neurotoxicology 101:26-35.
- - Shimada BK, Watanabe LM, Swanson S, Toh P, Seale LA. (2022) Selenium and selenoproteins in thermogenic adipocytes. Arch Biochem Biophys 731: 109445.
- - Cardoso BR, Cominetti C, Seale LA. (2022) Editorial: Selenium, Human Health and Chronic Disease. Front Nutr 8:827759.
- - Watanabe LM, Hashimoto AC, Torres DJ, Alfulaij N, Peres R, Sultana R, Maunakea AK, Berry MJ, Seale LA. (2021) Effect of statin treatment in obese selenium-supplemented mice lacking selenocysteine lyase. Mol Cell Endocrinol 533:111335.
- - Seale LA, Ogawa-Wong AN, Watanabe LM, Khadka VS, Menor M, Torres DJ, Carlson BA, Hatfield DL, Berry MJ. (2021) Adaptive thermogenesis in a mouse model lacking selenoprotein biosynthesis in brown adipocytes. Int J Mol Sci 22(2): 611.
- - Seale LA, Torres DJ, Berry MJ, Pitts MW. (2020) A role for selenium-dependent GPX1 in SARS-CoV-2 virulence. Am J Clin Nutr, 112(2): 447-448.
Recent Grants
- - 2021-present, PI: Selenium metabolism in cold-induced adaptive thermogenesis. NIH - National Institute of Diabetes and Digestive and Kidney Diseases (R01DK128390)
- - 2023-present, PI: Effects of Selenium on Adipocyte Lipids. Hawaii Community Foundation - Ingeborg v.F. McKee Fund (MedRes_2023_00002973)
- - 2022-present, Mentoring Director: Integrative Center for Precision Nutrition and Human Health (COBRE-Nutrition). NIH - National Institute of General Medical Sciences (P20GM139753)
- - 2023-present, Mentoring Coordinator: Integrative Center for Environmental Microbiomes and Human Health (COBRE-Microbiome). NIH - National Institute of General Medical Sciences (P20GM125508)
Current Graduate Students
- - Kayla Colaruotolo (PhD, Cell and Molecular Biology)
- - Princess Santiago (MS, Molecular Biosciences and Bioengineering)