Yanghua He , PhD
Assistant Professor – Human Nutrition, Food and Animal SciencesCollege of Tropical Agriculture and Human Resources – University of Hawai‘i at Mānoa
Work Email: yanghua.he@hawaii.edu
Research Interests
1. Livestock animal production: applying genomics and epigenomics approaches as well as computational methods to improve livestock animal production; 2. Diseases: utilizing high throughput sequencing datasets to elucidate the mechanisms of diseases in animals and humans and pinpointing the causal genetic variants of the disease using CRISPR-based technologies; 3. Nutrigenomics: studying the mechanisms of how different diets contribute to different phenotypes (eg. BMI for evaluating obesity) based on omics-data.
Recent Publications
- Jianan Liu, Fang Liu, Wentao Cai, Cunling Jia, Ying Bai, Yanghua He, Weiyun Zhu, Robert W. Li, Jiuzhou Song. Jejunal Microbiome and Bile Acids Induced by Diets in Angus Beef Cattle. BMC Animal Microbiome. Accepted. 2020
- Cicera R. Lazzarotto, Nikolay L. Malinin, Yichao Li, Ruochi Zhang, Yang Yang, Yanghua He, Xin Lan, Kasey Jividen, Varun Katta1, Natalia G. Kolmakova, Christopher T. Petersen, Qian Qi, Evgheni Strelcov, Samantha Maragh, Giedre Krenciute, Jian Ma, Yong Cheng, Shengdar Q. Tsai. CHANGE-seq reveals genetic and epigenetic effects on CRISPR–Cas9 genome-wide activity. Nature Biotechnology (2020). https://doi.org/10.1038/
s41587-020-0555-7 - Yanghua He, Bo Han, Yi Ding, Huanmin Zhang, Li Zhang, Chunfang Zhao, Ning Yang, and Jiuzhou Song. LincGALMD1 regulates viral gene expression in the chicken. Frontiers in Genetics, 10:1122. 2019 doi: 10.3389/fgene.2019.01122
Recent Grants
UH CTAHR Start-up FundCurrent Graduate Students