Lucia A. Seale , MS, PhD
Associate Research ProfessorPacific Biosciences Research Center, School of Ocean & Earth Science & Technology (SOEST)
Work Email: lseale@hawaii.edu
Research Interests
The metabolism of the micronutrient selenium and its impact in lipid biology, adipocyte physiology and obesity development.
Recent Publications
- - Ralston NVC, Raymond LJ, Gilman CL, Soon R, Seale LA, Berry MJ. (2024) Maternal seafood consumption is associated with improved selenium status: Implications for child health. Neurotoxicology 101:26-35.
- - Shimada BK, Watanabe LM, Swanson S, Toh P, Seale LA. (2022) Selenium and selenoproteins in thermogenic adipocytes. Arch Biochem Biophys 731: 109445.
- - Cardoso BR, Cominetti C, Seale LA. (2022) Editorial: Selenium, Human Health and Chronic Disease. Front Nutr 8:827759.
- - Watanabe LM, Hashimoto AC, Torres DJ, Alfulaij N, Peres R, Sultana R, Maunakea AK, Berry MJ, Seale LA. (2021) Effect of statin treatment in obese selenium-supplemented mice lacking selenocysteine lyase. Mol Cell Endocrinol 533:111335.
- - Seale LA, Ogawa-Wong AN, Watanabe LM, Khadka VS, Menor M, Torres DJ, Carlson BA, Hatfield DL, Berry MJ. (2021) Adaptive thermogenesis in a mouse model lacking selenoprotein biosynthesis in brown adipocytes. Int J Mol Sci 22(2): 611.
- - Seale LA, Torres DJ, Berry MJ, Pitts MW. (2020) A role for selenium-dependent GPX1 in SARS-CoV-2 virulence. Am J Clin Nutr, 112(2): 447-448.
Recent Grants
- - 2021-present, PI: Selenium metabolism in cold-induced adaptive thermogenesis. NIH - National Institute of Diabetes and Digestive and Kidney Diseases (R01DK128390)
- - 2023-present, PI: Effects of Selenium on Adipocyte Lipids. Hawaii Community Foundation - Ingeborg v.F. McKee Fund (MedRes_2023_00002973)
- - 2022-present, Mentoring Director: Integrative Center for Precision Nutrition and Human Health (COBRE-Nutrition). NIH - National Institute of General Medical Sciences (P20GM139753)
- - 2023-present, Mentoring Coordinator: Integrative Center for Environmental Microbiomes and Human Health (COBRE-Microbiome). NIH - National Institute of General Medical Sciences (P20GM125508)
Current Graduate Students
- - Kayla Colaruotolo (PhD, Cell and Molecular Biology)
- - Princess Santiago (MS, Molecular Biosciences and Bioengineering)