Joe Jarrett received a B.S. in chemistry from the University of Michigan in 1988. He obtained a Ph.D. in Biochemistry from the Department of Chemistry at the Massachusetts Institute of Technology in 1993, working with Peter T. Lansbury, Jr. on the mechanism of amyloid fibril formation in Alzheimer’s disease. He then returned to the University of Michigan for postdoctoral studies in the laboratory of Rowena G. Matthews, focusing on mechanistic studies of cobalamin-dependent methionine synthase. He was a member of the faculty of the Department of Biochemistry and Biophysics at the University of Pennsylvania from 1997 to 2005. He joined the Department of Chemistry at the University of Hawaii in 2006.