Floyd A. Reed

Floyd A. Reed

Associate Professor

An overall theme of my work is population genetics. I have interests in aspects of human evolution and in engineering safe and reversible gene drive systems.

Contact

Room

EDM 412

Phone

(808) 956-6489

Fax

(808) 956-4745

Website(s): 

Reed Lab Website

Academic Degrees

Ph.D. Cornell University, Genetics

B.A. Warren Wilson College, Chemistry

Research Interests

An overall theme of my work is population genetics. I have interests in aspects of human evolution and in engineering safe and reversible gene drive systems. More recently the lab has been involved in topics related to conservation genetics, invasive species, and harvested marine species.

Selected Publications

Evolutionary Genetic Engineering, Gene Drive, and Genetic Pest Management

Human Genetics

  • Tishkoff, S. A., Reed, F. A., Friedlaender, F. R., Ehret, C., Ranciaro, A., Froment, A., ... & Ibrahim, M. (2009). The genetic structure and history of Africans and African Americans. Science, 324(5930), 1035-1044. https://doi.org/10.1126/science.1172257
  • Friedlaender, J. S., Friedlaender, F. R., Reed, F. A., Kidd, K. K., Kidd, J. R., Chambers, G. K., ... & Merriwether, D. A. (2008). The genetic structure of Pacific Islanders. PLoS Genetics, 4(1), e19. https://doi.org/10.1371/journal.pgen.0040019
  • Tishkoff, S. A., Gonder, M. K., Henn, B. M., Mortensen, H., Knight, A., Gignoux, C., ... & Reed, F. A. (2007). History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variation. Molecular Biology and Evolution, 24(10), 2180-2195. https://doi.org/10.1093/molbev/msm155
  • Tishkoff, S. A., Reed, F. A., Ranciaro, A., Voight, B. F., Babbitt, C. C., Silverman, J. S., ... & Ibrahim, M. (2007). Convergent adaptation of human lactase persistence in Africa and Europe. Nature Genetics, 39(1), 31. https://doi.org/10.1038/ng1946
  • Reed, F. A., & Tishkoff, S. A. (2006). African human diversity, origins and migrations. Current Opinion in Genetics & Development, 16(6), 597-605. https://doi.org/10.1016/j.gde.2006.10.008
  • Gonder, M. K., Mortensen, H. M., Reed, F. A., de Sousa, A., & Tishkoff, S. A. (2006). Whole-mtDNA genome sequence analysis of ancient African lineages. Molecular Biology and Evolution, 24(3), 757-768. https://doi.org/10.1093/molbev/msl209
  • Reed, F. A., & Aquadro, C. F. (2006). Mutation, selection and the future of human evolution. TRENDS in Genetics, 22(9), 479-484. https://doi.org/10.1016/j.tig.2006.07.005
  • Reed, F. A., Akey, J. M., & Aquadro, C. F. (2005). Fitting background-selection predictions to levels of nucleotide variation and divergence along the human autosomes. Genome Research, 15(9), 1211-1221. https://doi.org/10.1101/gr.3413205
  • Reed, F. A., Kontanis, E. J., Kennedy, K. A., & Aquadro, C. F. (2003). Brief communication: ancient DNA prospects from Sri Lankan highland dry caves support an emerging global pattern. American Journal of Physical Anthropology, 121(2), 112-116. https://doi.org/10.1002/ajpa.10211
  • Aquadro, C. F., DuMont, V. B., & Reed, F. A. (2001). Genome-wide variation in the human and fruitfly: a comparison. Current Opinion in Genetics & Development, 11(6), 627-634. https://doi.org/10.1016/S0959-437X(00)00245-8

Book

  • Láruson, Á. J., and F. A. Reed. (book contract signed 2018). Population Genetics with R: A Practical Guide, ISBN 9780198829539, Oxford University Press.

Book Chapters

  • Reed, F. A., Traulsen, A., & Altrock, P. M. (2013). Underdominance. In Brenner's Encyclopedia of Genetics (pp. 247-249). Elsevier. https://doi.org/10.1016/j.jtbi.2011.04.032
  • Reed, F. A. (2012). Modern Human Migrations: The First 200,000 Years. In Migrations: Interdisciplinary Perspectives (pp. 315-326). Springer, Vienna. https://doi.org/10.1007/978-3-7091-0950-2_29
  • Allaby, R. G., Friedlaender, F. R., Reed, F. A., Kidd, K. K., Kidd, J. R., Chambers, G. K., ... & Merriwether, D. A. (2010). Prehistoric Pacific Population Movements. In The Global Origins and Development of Seafaring, 143-157. ISBN: 978-1-902937-52-6, McDonald Institute for Archaeological Research.
  • Reed, F. A. (2008). Are Humans Still Evolving?. eLS. https://doi.org/10.1002/9780470015902.a0020794

Patent Applications

  • Reeves, G. and Reed, F., Max-Planck-Gesellschaft zur Forderung der Wissenschaften, (2015). Stable transformation of a population and a method of biocontainment using haploinsufficiency and underdominance principles. U.S. Patent Application 14/654,450. https://patents.google.com/patent/US20150373937A1
  • Tishkoff, S.A. and Reed, F.A., University of Maryland, (2008). Single nucleotide polymorphisms and the identification of lactose intolerance. U.S. Patent Application 11/976,676. https://patents.google.com/patent/WO2008057265A2

Other Publications

  • Evolutionary Game Theory and Dynamical Systems

    • Traulsen, A., & Reed, F. A. (2012). From genes to games: cooperation and cyclic dominance in meiotic drive. Journal of Theoretical Biology, 299, 120-125. https://doi.org/10.1016/j.jtbi.2011.04.032
    • Milinski, M., Sommerfeld, R. D., Krambeck, H. J., Reed, F. A., & Marotzke, J. (2008). The collective-risk social dilemma and the prevention of simulated dangerous climate change. Proceedings of the National Academy of Sciences, 105(7), 2291-2294. https://doi.org/10.1073/pnas.0709546105
    • Reed, F. A. (2007). Two-locus epistasis with sexually antagonistic selection: a genetic Parrondo's paradox. Genetics, 176(3), 1923-1929. https://doi.org/10.1534/genetics.106.069997
    • in addition to publications in other categories above
  • Conservation Genetics, Invasive Species, Genetics of Harvested Species

    • Kingston, S. E., Martino, P., Melendy, M., Reed, F. A., & Carlon, D. B. (2017). Linking genotype to phenotype in a changing ocean: inferring the genomic architecture of a blue mussel stress response with genome‐wide association. Journal of Evolutionary Biology. 31(3): 346–361. http://dx.doi.org/10.1111/jeb.13224
    • Shafer, A. B., Wolf, J. B., Alves, P. C., De Meester, L., Ekblom, R., Fior, S., ... & Norman, A. J. (2016). Reply to Garner et al. Proc. Natl. Acad. Sci. USA, 108, 12348. https://doi.org/10.1016/j.tree.2015.11.010
    • Shafer, A. B., Wolf, J. B., Alves, P. C., Bergström, L., Bruford, M. W., Brännström, I., ... & Fawcett, K. D. (2015). Genomics and the challenging translation into conservation practice. Trends in Ecology & Evolution, 30(2), 78-87. https://doi.org/10.1016/j.tree.2014.11.009
    • Stemshorn, K. C., Reed, F. A., Nolte, A. W., & Tautz, D. (2011). Rapid formation of distinct hybrid lineages after secondary contact of two fish species (Cottus sp.). Molecular Ecology, 20(7), 1475-1491. https://doi.org/10.1111/j.1365-294X.2010.04997.x
  • Classical and Molecular Genetics

    • Tabios, M., L. Boell, and F. A. Reed. (2014) A new mutation of PDA synthase, sepia, isolated from wild Drosophila melanogaster. Drosophila Information Service 97, 176–177. http://www.ou.edu/journals/dis/DIS97/Tabios%20176.pdf
    • Kontanis, E. J., & Reed, F. A. (2006). Evaluation of Real‐Time PCR Amplification Efficiencies to Detect PCR Inhibitors. Journal of Forensic Sciences, 51(4), 795-804. https://doi.org/10.1111/j.1556-4029.2006.00182.x
    • Reed, F. A., Reeves, R. G., & Aquadro, C. F. (2005). Evidence of susceptibility and resistance to cryptic X-linked meiotic drive in natural populations of Drosophila melanogaster. Evolution, 59(6), 1280-1291. https://doi.org/10.1554/05-021 

Floyd Reed is also a faculty member of the Zoology Graduate Program, University of Hawaiʻi at Mānoa, a faculty member of the Ecology, Evolution and Conservation Biology (EECB) Graduate Specialization Program, University of Hawaiʻi at Mānoa, an affiliate faculty member of the Anthropology Graduate Program, University of Hawaiʻi at Mānoa, and an Associate Editor for the Journal of Heredity.

(last updated March 16, 2018)