Departmental Assessment Update - Medicine Report

Department: Biomedical Science: Cell and Molecular Biology
Program: MS/PhD
Level: Graduate

1. List in detail your graduate Student Learning Outcomes (SLOs) for each degree/certificate offered.

. Master of Science in Biomedical Sciences (Cell and Molecular Biology) 

1. Sufficient breadth and depth of knowledge to assume responsibility for teaching classes in Cell and Molecular Biology at least at the undergraduate level, and teaching experience in these and related topics;

 

1. Knowledge of the process of research, including: familiarity with techniques for searching the literature; principles of measurement; and practical experience in the design and conduct of scientific experiments, collection of data, and interpretation of data sufficient to enable them to interpret current literature, and to embark upon the next (doctoral) level of development as researchers;

 

1. Familiarity with the mechanics of scientific reporting sufficient to enable them to prepare a publication for a scholarly journal;

 

1. Experience with oral presentation of material sufficient to enable them to prepare and deliver reports on their work at seminars or meetings of scientific societies;

 

1. A degree of understanding and scientific maturity sufficient to enable them to assess the work of others;

 

1. An understanding of the administrative procedures common to academic departments.

 

1. PhD in Biomedical Sciences (Cell and Molecular Biology)

 

1. Sufficient breadth and depth of knowledge to assume responsibility for teaching classes in Cell and Molecular Biology at the undergraduate level, and sufficient sophistication in one specialty area of Cell and Molecular Biology to teach medical and graduate level course material in that area;

 

1. Specialized knowledge in an area of research, including familiarity with the literature and techniques common to their area of specialization; and practical experience in the design and conduct of scientific experiments, collection of data, and interpretation of data sufficient to enable them to initiate and continue research successfully as independent investigators and to supervise student work in that area;

 

1. Familiarity with the mechanics of scientific reporting sufficient to enable them to publish their work in scholarly journals;

 

1. Experience with oral presentation of material sufficient to enable them to prepare and deliver reports on their work at seminars or meetings of scientific societies;

 

1. A degree of understanding and scientific maturity sufficient to enable them to assess and criticize constructively the work of others;

 

1. An understanding of the administrative procedures common to academic departments.

 

2. Where are these SLOs published (e.g., departmental web page)?

These SLOs are all listed on the Cell and Molecular Biology Graduate Program web page at http://www.hawaii.edu/graduatestudies/fields/html/departments/cd/cmb/cmb.htm and portions are distributed to prospective applicants by e-mail. 

3. Explain how your SLOs map onto your curriculum, i.e., how does your program of graduate studies produce the specific SLOs in your students?

A. SLO 1, Knowledge:  Courses:   

Except for required courses, the program of study will be tailored to the needs and future career plans of each individual graduate student.  A minimum of 30 credits is required for the MS degree.  There is not a specific credit requirement for the PhD.  Once admitted to PhD candidacy, the student’s advisory committee determines what further coursework, if any, the student shall take. 

Required courses for incoming MS and PhD students include the first year core course, CMB 621-622, Cell and Molecular Biology, the Ethics in Biomedical Research course, CMB 626, and additional courses as required by each student’s academic program.  

Most students will do some directed reading or directed research, especially Plan B MS students and PhD students who, for whatever reason, have not begun a research program under a faculty mentor who will chair their Advisory Committee.  Students will enroll in CMB 699 in order to receive credit for this work, with the number of credits being agreed upon by the faculty conducting the 699, the Chair of the Graduate Program Committee, and the student. 

Incoming PhD students may petition the Graduate Program Committee to be exempted from these required courses when the student has already satisfactorily completed equivalent courses at another institution, but in general, students should expect that they will take these courses. 

            B. SLO 1, Teaching 

      Graduate students are encouraged to participate in teaching by demonstrating in laboratory sessions, particularly within their intended area of specialty.  Their participation as Graduate Teaching Trainees should bring them into direct contact with students and afford them an appreciation of the problems associated with the administration of courses.  To this end, Graduate Teaching Trainees should participate in meetings of course committees and they should also attend the lectures.  Whenever possible, students will be permitted to select the courses in which they will instruct; however, instances may arise where it will be necessary to assign individuals to specific courses within the general area of their competence. 

      A maximum of 10 hours/week may be spent in teaching, except when students receive their major financial support in the form of a teaching stipend (Graduate Teaching Assistantship).  Students holding Graduate Teaching Assistantships will be assigned duties in accordance with Graduate Division guidelines.   

      C. SLO 2, Research:   

The first year graduate student will consult with the mentor to choose a research project early in the graduate program.  Following passage of the Qualifying Exam, the graduate student and the advisor are encouraged to informally discuss the possible projects with potential members of the Advisory Committee and/or other faculty members in order to determine the scientific feasibility of the research scheme and suitability with respect to departmental facilities and personnel.  Based on these discussions, the graduate student and mentor should complete Appendix 1 (Initial Research Summary) as soon as feasible and submit it to the Graduate Program Committee for approval.   

      Following approval of this initial research proposal, the graduate student will be required to meet with his/her Advisory Committee and present a final research proposal.  This presentation should establish a comprehensive background for the project and preliminary results, if available, should be discussed.  This proposal should include details of the research program with the experimental particulars.    The proposal will be subject to approval by the Advisory Committee and forwarded to the Departmental Graduate Committee for final approval.  If significant problems are identified at this time, the student will present a revised program approximately two months later. 

The Graduate Program Committee will review each graduate student’s work at the end of the academic year.  The graduate student and his/her advisor will meet with the Committee to review the student’s progress for the past academic year.  As well, a tentative schedule for the Comprehensive Examination will be provided.  The graduate student is required to complete the form “Annual Review of Graduate Student’s Progress”  (Appendix 2, page 11) and present the information to the Departmental Graduate Committee during his/her annual review. 

      D. SLO 3, 4, 5, Scientific Maturity:   

A graduate student’s academic maturity is nurtured largely through his/her exposure to the scientific acumen of departmental colleagues.  The active participation of graduate students in seminars, discussions and study groups accelerates this process.  In order to stimulate the development of scientific maturity: 

1. A graduate student in the MS program will give one seminar near the completion of the program, typically in the second year.  A PhD student will give one seminar in the second year of his/her program and a second seminar near completion of the degree.  In the case of a MS student who transfers to the PhD program, the seminar typically given in the second year near completion of the MS will serve as a portion of the Qualifying Examination;

 

1. Graduate students should participate in study groups related to the area of their specialization where appropriate.  These study groups provide a situation in which students can present and evaluate their own work as well as that of others in an informal atmosphere;

 

1. Graduate students are ordinarily expected to attend special seminars arranged by the Cell and Molecular Biology Graduate Program or seminars in other departments when appropriate;

 

1. Graduate students will present a written report of their research once annually to the Graduate Program Committee.  Additional written reports may be requested by the Chairperson of the Advisory Committee.  This gives the student an opportunity to formulate his/her progress in writing.  Parts of this report may be useful in the preparation of the thesis;

 

1. Graduate students will participate in scientific meetings to the extent that funds for travel allow.

 

E. SLO 6, Administrative Procedures:   

Graduate students will be exposed whenever practicable to the processes of decision making and administration of the Department.  This exposure will be achieved in part by assigning graduate students to sit on committees of the Department, and they may serve as assistants to faculty members having specific responsibilities within the Departmental structure. 

All graduate students will be permitted to attend open faculty meetings of the Department as observers.  Each autumn the graduate students of the Department will elect a graduate student representative who will have full voting privileges at these meetings, and with whom the Department can consult on any matters concerning graduate student affairs.  Students will also elect a representative to the campus-wide Graduate Student Organization (GSO). 

4. What population(s) is covered by your assessment(s)?

All students admitted to the MS and PhD programs in Cell and Molecular Biology are covered by the assessments described herein. 

5. Please list/describe all the assessment events and devices used to monitor graduate student progress through the program. Consider the following questions:

• How are written exams used to assess graduate students?

A. Written examinations include midterm and final exams in the Fall and Spring semesters for the core course, CMB 621-622, Cell Molecular Biology, that is required of all first year Ph.D. students, and written qualifying exams given in the fall of the second year to all Ph.D. students. Exam questions are written and graded by a cross-section of the CMB graduate faculty for both the CMB course and qualifying exam, and results tabulated by the graduate program administrator. Written exams are the main basis for grades in our courses.  These are constructed, as much as possible, using questions with which we have prior experience.  They are intended to define a minimal competence in the subject matter of each course.  Together with other behaviors defined by the instructor (class participation, reviewing a classic or recent paper, literature review paper, etc.) they form the basis for the course grade.

B. Literature review papers are part of the evaluation scheme in some courses.  They are intended to exercise literature search techniques, critical thinking, and expository writing skills.  They are evaluated for these attributes by the faculty who teach the subject matter of the paper.

C. The integrative course, Cell and Molecular Biology, uses essay exams to test students’ ability to explain interrelationships between organ systems in the context of a global stressor (exercise), or to explain why certain phenomena are important to homeostasis in this context.

D. The Qualifying and Comprehensive Exams are essay exams, in which time limitations on the amount of knowledge one can demonstrate are minimal.  These are intended to test depth of knowledge in several areas of Cell and Molecular Biology and supporting biological sciences.  They are evaluated by the faculty who delivered the corresponding content and wrote the questions. 

  – How are independent and/or culminating projects (theses, dissertations, performances, capstone courses, etc.) used to assess graduate students? 

All of our programs have a “culminating experience”.  These are: For Plan A MS students, the masters degree thesis; for Plan B MS students, the plan B paper (which is either an in-depth literature review, or the literature review, problem definition and experimental design for a research project); for PhD students, the doctoral dissertation. 

These culminating experiences are the basis for judging the attainment of research expertise (SLO 2, above), and the acquisition of scientific maturity (which are the attributes listed in SLOs 3, 4, and 5).  Each paper/thesis/dissertation is reviewed by a faculty committee chosen for background in the relevant subject matter.  To the extent that deficiencies are identified in the student’s product, remediation of those deficiencies becomes an opportunity for further, focused, development of the student. 

  – How are oral presentations/reports/performances used to assess graduate students? 

Oral presentations are required in some of our courses, in journal clubs, and in the culminating experience. Oral presentations of case studies are required of all graduate students in Ethics in Biomedical Research, a newly added requirement of the CMB Ph.D. program. A new requirement is also being implemented whereby all Ph.D. students will present formal departmental seminars in the third year of their Ph.D. dissertation program. This is in addition to the teaching experience most of our students get.  Oral presentations are used to provide feedback, and remedial assistance if needed, on organizing the flow of a presentation, on how to prepare materials for presentation, and on articulate delivery.  Both faculty observation and student evaluations of instructor performance and are used to provide feedback to graduate students on their ability to communicate Cell and Molecular Biology subject matter effectively. 

6. Please list/describe how your graduate students contribute to your discipline/academic area? Consider the following questions:

 To what extent do your graduate students present their work at professional conferences? 

Conference attendance, presentations and publication are summarized in the tables below for current students and recent graduates. 

 

NAME	ENTERED	CONFERENCES	DATE	PRESENTED
AGSALDA, Melissa	PhD 2005	CMB Program Graduate Retreat	2007/Aug	Oral
AMIAN, Czarina	PhD 2007	FASEB Conference Biomedical Research Conference for Minority Students	2006	Poster Poster
ARCHER, Crystal	PhD 2006	Biomedical Sciences Symposium/Honolulu	2007/March	Poster
BARNHILL, Jason	PhD 2006	None
BURGESS, Sarah L.	PhD 1998
CALIVA, Maisel	PhD 2007	ASBMB Annual Meeting Butler U Undergrad Research Conference	2006 2005	Poster Poster
CAMPORA, Cara Linnell	PhD 2004	Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu 3rd Symposium on Harmful Algae in the US	2006/April 2005/April 2005/Oct	Poster Poster Poster
COCHRANE, Kimberly	PhD 2005	CMB Graduate Program Retreat Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu	2007/Aug 2005/April 2004/April	Oral Poster Poster
COUSSENS, Matthew J.	PhD 2004	CMB Graduate Program Retreat Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu CMB Graduate Program Retreat Plant & Animal genome Conf/San Diego U Undergrad Research & Arts Forum/MI	2007/Aug 2007/March 2006/April 2005 2003 2002	Oral Oral Poster Oral Oral/Poster Oral
DILLER, Karl	PhD 2005	CMB Graduate Program Retreat	2005/Aug	Oral
DING, Chaonan	PhD 2001	Biomedical Sciences Symposium/Honolulu	2005/April	Poster
		Soc of Neuroscience 34th Meeting/CA	2004/Oct	Poster
		CMB Graduate Program Retreat	2004/May	Oral
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
		NAVBO Devel Vascular Biology WS/CA	2004/Feb	2 Posters
		Asia Pac Scientific Forum/AHA/Honolulu	2003/June	Poster
DOMINGUEZ, Kenneth	MS 2005	CMB Graduate Program Retreat	2007/Aug	Oral
FOGELGREN, Ben	PhD 1999	Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu FASEB Write Winning Grants Seminar/HI 96th Meet American Assoc of Cancer Res/CA 2nd Nat Meet Amer Soc for Matrix Biology/CA CMB Graduate Program Retreat	2007/March 2006/April 2005/April 2005/Mar 2005/April   2004/Nov	Poster Poster Poster Poster Poster   Poster Oral
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
		American Society for Cell Biology 43rd Meet/CA	2003/Nov	Poster
		American Heart Association 2nd Asia/Pac/Hon	2003/June	Poster
		1st Nat Meet Amer Soc for Matrix Biology/CA	2002/Nov	Poster
		Annual Meet Amer Society Cell Biology/DC	2001/Dec	Poster
GAWECKA, Joanna	PhD 2005	None
HARA, Cynthia	MS 2004	Biomedical Sciences Symposium/Honolulu	2005/April	Poster
HAINES, Bryan	PhD 2004	CMB Graduate Student  Retreat Biomedical Sciences Symposium/Honolulu	2005/Aug 2005/April	Oral Poster
HARVEY, Eiko	MS 2006	None
HEW, Brian	PhD 2005	Biomedical Sciences Symposium/Honolulu CMB Graduate Program Retreat Biomedical Sciences Symposium/Honolulu	2007/April 2005/Aug 2005/April	Poster Oral Poster
Horton, Jaime	PhD 2006	None
HU, Qirui	PhD 2001
KANEMARU, Kelli	PhD 2002	Biomedical Sciences Symposium/Honolulu	2007/March	Poster
KHEMMANI, Mark	MS 2007	None
KIM, Courtney	MS 2005	Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu	2007/March 2006/April	Poster Poster
LINNOLT, Michael	PhD 2003	None
LOEFFLER, Jorik	PhD 2007	None
MAEDA, Gregg	PhD 2002	CMB Graduate Program Retreat	2004/May	Oral
MOIKEHA, Nickol	MS 2007	None
MOLNAR, Janos	PhD 2003	FASEB Write Winning Grants Seminar/Honolulu	2005/Mar
		CMB Graduate Program Retreat	2004/May	Oral
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
		2nd Nat Meet Amer Soc for Matrix Biology/CA	2004/Nov	Poster
		International Society of Differentiation/Honolulu	2004/Sept	Poster
		American Society for Cell Biology 43rd Meet/CA	2003/Dec	Poster
NAEOLE, Chrystie	PhD 2002	Biomedical Sciences Symposium/Honolulu Albert L. Tester Memorial Symposium/Honolulu Albert L. Tester Memorial Symposium/Honolulu CMB Graduate Program Retreat Albert L. Tester Memorial Symp/Honolulu	2006/April 2006 2005 2005/Aug 2004/April	Poster Poster/Oral Poster Oral Poster
		Soc Adv of Chicanos & Native Amer/TX	2004	Poster
		CMB Graduate Program Retreat	2004/May	Oral
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
		Soc Adv of Chicanos & Native Amer/NM	2003	Poster
		HI St Biomed Research Infrast Netw Sym/HI	2003	Poster
		Biomedical Sciences Symposium/Honolulu	2003	Poster
		Albert L. Tester Memorial Symposium/Honolulu	2002	Poster
PANG, Xiaosha	PhD 2006	None
PITTS, Matthew	PhD 2004	CMB Graduate Program Retreat Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu CMB Graduate Program Retreat	2007/Aug 2007/March 2006/April 2005/April 2005/Aug	Oral Poster Poster Poster Oral
RAMAN, Arjun	PhD 2007	None
REEVES, Mariclair	PhD 2007	Biomedical Sciences Symposium/Honolulu	2007/March	Poster
SEKI, Jennifer	MS  2004	Biomedical Sciences Symposium/Honolulu	2005/April	Poster
SHARMA, Amrish	PhD 2006	None
SQUIRES, Jeffrey	PhD 2003	CMB Graduate Student Retreat Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu CMB Graduate Student retreat Biomedical Sciences Symposium/Honolulu	2007/Aug 2007/March 2006/April 2005/Aug 2005/April	Oral Poster Poster Poster Poster
STIEGLITZ, Lael	PhD 2007	None
STILLWELL, RJ	PhD 2005	Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu	2006/April 2005/April	Poster Poster
SZAUTER, Kornelia	PhD 2003	FASEB Write Winning Grants Seminar/Honolulu	2005/Mar
		CMB Graduate Program Retreat	2004/May	Oral
		Biomedical Sciences Symposium/Honolulu	2004/April	Poster
		2nd Nat Meet Amer Soc for Matrix Biology/CA	2004/Nov	Poster
		International Society of Differentiation/Honolulu	2004/Sept	Poster
		American Soc. Cell Biology 43rd Meet/CA	2003/Dec	Poster
TAKASAKI, Kelsie	PhD 2004	None 6/30/05
TAKEUCHI, Kenneth	PhD 2002	CMB Graduate Program Retreat Biomedical Sciences Symposium/Honolulu	2007/Aug 2006/April	Oral Poster
TARNAY(Cogbill), Jolene	PhD 2003	CMB Graduate Program Retreat Biomedical Sciences Symposium/Honolulu Biomedical Sciences Symposium/Honolulu Biomedical Symposium/Honolulu	2007/Aug 2007/March 2006/April 2005/April
		CMB Graduate Program Retreat	2004/May	Oral
		Biomedical Symposium/Honolulu	2004/April	Poster
TEETERS, Kelsa	PhD 2004	CMB Graduate Program Retreat Biomedical Sciences Symposium/Honolulu Biomedical Symposium/Honolulu	2007/Aug 2007/March 2006/April	Oral Poster Poster
		American Thoracic Society/San Diego	May	Poster
VALLIERE, Justin	PhD 2007	None
WALLS, Alison	MS 2003	None
WONG, Mayee	PhD 2004	CMB Graduate program Retreat CMB Graduate Program Retreat Tropical MedConference/Honolulu EWC Emerging Infectious Diseases	2007/Aug 2005/Aug 2005/April	Oral Oral Poster
YOUNG-ROBBINS, Shirley	MS 2005	CMB Graduate Program Retreat	2006	Oral

 

Publications of Research Completed by Current Students and Recent Graduates During Their Training
Name (Years in Training)	Publication (Authors, Year,Title, Journal)
Agsalda, Melissa (2005-present)	None
Amian, Czarina (2007-present)	None
Archer, Crystal (2006-present)	None
Barnhill, Jason (2006-present)	Barnhill JC, Stokes AJ, Koblan-Huberson M, Shimoda LM, Muraguchi A, Adra CN, Turner H.(2004) RGA protein associates with a TRVP ion Channel during Biosynthesis and trafficking. J Cel Biochem. 2004 Mar 1;91(4):808-20
Burgess, Sarah (1998-2005)	Burgess, SL, Fleischer, RC (2005) Isolation and characterization of polymorphic microsatellite loci in the Hawaiian flycatcher, the elepaio(Chasiempis sandwichensis). Molecular Ecology.
Caliva, Maisel (2007-present)	None
Campora, Cara (2004-present)	Campora CE, Hokama Y, JSM Ebesu(2006) Comparative Analysis of purified Pacific and Caribbean Ciguatoxin Congeners and Related Marine Toxins Using Modified ELISA Technique. Journal of Laboratory Anal. 20:121-5. Hokama Y, Chun KE, Campora,CE, Higa N, Suma C, Hamajima A, Isober M(2006) Biological Activity of the Functional Epitope of Ciguatoxin Fragment AB on the Neuroblastoma sodium channel in tissue culture.
Cochrane, K (2002-present)	Lendvay TS, Sweet R, Han CH, Soygur T, Cheng JF, Plaire JC, Charleston JS, Charleston LB, Bagai S, Cochrane K, Rubio E, Bassuk JA.(2007) Compensatory Paracrine Mechanisms that Define the Urothelial response to Injury in Partial Bladder Outlet Obstruction. Am J Physiol Renal Physiol. 200-7 Jul 3 Bassuk, JA, Cochrane K Mitchell ME (2004) Induction of Urothelial Cell Proliferation by Fibroblast Growth Factor-7 in RAG1-Deficient Mice. Bladder Disease: Research Concepts and Clinical Applications. Kluwer Academic/Plenum Press. Bassuk JA, Cochrane K, Mitchell ME(2003) Induction of urothelial Cell Proliferation by Fibroblast growth factor -7 in RAG-1-deficient mice. Adv Exp Med Biol. 2003;539(PtB):623-33.
Coussens, MJ (2004-present)	Coussens, PM, Tooker B, Nobis W, Coussens MJ (2001) Genetics Characterization of the NRAMP1 Gene.  Research Forum 2001, Michigan State University, East Lansing, MI. Coussens PM, Tooker BC, Nobis W, Coussens MJ. (2001) Genetics and Genomics of Susceptibility to Mycobacterial Infection in Cattle. Initiative for Future Agriculture and Food Systems 2001. Coussens PM, Coussems MJ, Tooker BC, Nobis W (2004) Structure of the bovine natural resistance associated macrophage protein (NRAMP1)gene and identification of a novel polymorphism. DNASeq. 15(1):15-25.
Ding, C (2001-2005)	Ding C, He Q, Li PA. (April 2005) Diabetes increases expression of ICAM after a brief period of cerebral Ischemia. J Neuroimmunology 161(1-2):61-7. Ding C, He Q, Li PA (Aug 2004) Activation of cell death pathway after a brief period of global ischemia in diabetic and non-diabetic animals. Exp Neuro. 188(2):421-9. He QP, Ding C, Li PA(Dec 2003) Effects of Hyperglycemic and normoglycemic cerebral ischemia on phosporylation of c-jun NH2-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK). Cell Mol Bio. 49(8):1241-7.
Fogelgren, B. (2000-2005)	Asuncion L, Fogelgren B, Fong KS, Fong SF, Kim Y, Csiszar K. (2001) A novel human lysyl oxidase-like gene (LOXL4) on chromosome 10q24 has an altered scavenger receptor cysteine rich domain. Matrix Biol. 20:487-91. Mink M, Fogelgren B, Olszewski K, Maroy P, Csiszar K (2001) .A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 74:234-44. Molnar J, Fong KS, He QP, Hayashi K, Kim Y, Fong SF, Fogelgren B, Szauter KM, Mink M, Csiszar K. (2003) Structural and functional diversity of lysyl oxidase and the LOX-like proteins. Biochim Biophys Acta. 1647:220-4. Hayashi K, Cao T, Passmore H, Jourdan-Le Saux C, Fogelgren B, Khan S, Hornstra I, Kim Y, Hayashi M, Csiszar K. (2004) Progressive hair loss and myocardial degeneration in rough coat mice: reduced lysyl oxidase-like (LOXL) in the skin and heart. J Invest Dermatol. 123:864-71. Molnar J, Ujfaludi Z, Fong SF, Bollinger JA, Waro G, Fogelgren B, Dooley DM, Mink M, Csiszar K. (2005) Drosophila lysyl oxidases Dmloxl-1 and Dmloxl-2 are differentially expressed and the active DmLOXL-1 influences gene expression and development. J Biol Chem. 280:22977-85. Fogelgren B, Polgar N, Szauter KM, Ujfaludi Z, Laczko R, Fong KS, Csiszar K. (2005) Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. J Biol Chem. 280:24690-7.
Hew, B (2002-present)	Fritzinger DC, Hew BE, Thorne M, Vogel CW (2004) Functional Characterization of cobra venom factor/cobra C3 hybrid proteins. Mol. Immunol. 41, 23 Hew BE, Thorne M, Fritzinger DC, Vogel CW (2004)Humanized cobra venom factor (CVF): Generation of Human C3 derivatives with CVF-like function.  Mol Immunol. 41,244 Kock MA, Hew BE, Bammert H, Fritzinger DC, Vogel CW (2004) Structure and function of recombinant Cobra Venom Factor. J Biol Chem. 279, 30836-30843. Vogel CW, Fritzinger DC, Hew BE, Thorne M (2004) Generation of “humanized cobra venom factor” for therapeutic complement depletion. Third International Conference on Innate Immunity. Crete, Greece. Vogel CW, Fritzinger DC, Hew BE, Thorne M, Bammert, H (2004) recombinant cobra venom factor. Mol Immunol. 41, 91-199. Fritzinger DC, Hew BE, Wehrhahn D, Vogel CW (2003) Functional Characterization of Cobra Venom Factor/Cobra C3 Hybrid Protein. Mol Immunol. 40, 199.
Horton (Lachmann), Jaime (2005-present)	Sapra R, Gaucher SDP, Lachmann JS, Buffleben GM, Chirica GS, Comer JE, Peterson JW, Chopra AK, Singh AK(2006) Proteomic analyses of murine macrophanges treated with Bacillus anthracis lethal toxin. Microb Pathog. Oct-Nov; 41(4-5): 157-67. Chirica G, Lachmann J, Chan J(2006) Size exclusion chromatography of microliter volumes  for on-line use in low-pressure microfluidic systems. Anal Chem. 2006 Aug 1;78(15):5362-8.
Howard, JP (2001-present)	Bachmann AS, Heiligtag S, Howard JP, David K, Vogel CW(2002) Advances in Neuroblastoma Research . Paris, France.
Kanemaru, KK (2002-present)	Kanemaru KK, Tuthill KK, Sidell N, Wada RK(2007) Retinoic acid induced downregulation of MYCN is not mediated through changes in Sp1/Sp3. Pediatric Blood Cancer June 6 2007. Tuthill MC, Wada RK, Arimoto JM, Sugino CN, Kanemaru KK, Takeuchi KK, Sidell N.  N-myc oncogene expression in neuroblastoma is driven by Sp1 and Sp3.  Mol Genet Metab 80:272-280, 2003.
Khemmani, Mark (2007-present)	None
Killebrew, DA (1999-2005)	Killebrew D, Shiramizu B(2004) Preferential HIV-1 integration sites in macrophages and HIV-associated malignancies. Cell Mol Biology. Online Pub: OL581-9 Killebrew DA, Troelstrup D, Shiramizu B (2004) Pathogenesis of HIV-associated non-Hodgkin lymphoma. Curr HIV Res. 2(3):215-21.
Maeda, G (2001-2007)	Urban Z, Zhang J, Davis EC, Maeda GK, Kumar A, Stalker H, Belmont JW, Boyd CD, Wallace MR (2001) Supravalvular aortic stenosis: genetic and molecular dissection of a complex mutation in the elastin gene.  Hum Genetics. 109(5):512-2
Matus, DQ (2001-2005)	Pang K, Matus DQ, Martindale MQ. (2004) The ancestral role of COE genes may have been in chemoreception: evidence from the development of the sea anemone, Nematostella vectensis (Phylum Cnidaria; Class Anthozoa). Dev Genes Evol. In press
Molnar, J (2001–2006)	Molnar J, Fong KS, He QP, Hayashi K, Kim Y, Fong SF, Fogelgren B, Szauter KM, Mink M, Csiszar K. (2003) Structural and functional diversity of lysyl oxidase and the LOX-like proteins. Biochim Biophys Acta. 1647:220-4. Molnar J, Ujfaludi Z, Fong SF, Bollinger JA, Waro G, Fogelgren B, Dooley DM, Mink M, Csiszar K. (2005) Drosophila lysyl oxidases Dmloxl-1 and Dmloxl-2 are differentially expressed and the active DmLOXL-1 influences gene expression and development. J Biol Chem. 280:22977-85.
Monteilh-Zoller, MK (2002-2005)	Monteilh-Zoller MK, Hermosura MC, Nadler MJS, Scharenberg AM, Penner R and Fleig A. (2003) TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. Journal of General Physiology 121, 49-6 Hermosura MC, Monteilh-Zoller MK, Scharenberg AM, Penner R and Fleig A. (2002) Dissociation of the store-operated calcium current ICRAC and the Mg2+-nucleotide-regulated metal ion current MagNuM. Journal of Physiology, 539.3, 445-458. Prawitt D, Monteilh-Zoller MK, Brixel L, Christian Spangenberg C, Zabel B, Fleig A & Penner R. (2003) TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i. PNAS 100 , 15166-15171.
Naeole, CKM (2002-present)	Naeole CKM and Haymer D. (2003) Use of oligonucleotide arrays for molecular taxonomic studies of closely related species in the oriental fruit fly (Bactrocera dorsalis) complex. Molecular Ecology Notes 3: 662-665.
Pang, Xiaosha (2006-present)	None
Pitts, Matthew (2004-present)
Raman, Arjun (2007-present)	None
Reeves, Mariclair (2007-present)
Seki, Jennifer (2004-present)	Wallick CJ, Gamper I,  Gamper, I, Thorne M, Feith DJ, Takasaki K, Wilson SM, Seiki JA, Pegg, AE, Byus, C, Bachmann, AS (2005) Key role for p27-Kip-1 retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest  in MYCN-amplified human neuroblastoma cells. Oncogene. 24: 5606-5618
Sharma, Amrish (2006-present)
Sotolongo, B  (2000-present)	Sotolongo B, Ward WS (2000) DNA loop domain organization: the htree-dimensional genomic code. J Cell Biochem Suppl. 35:2223-6. Sotolongo B, Lino E, Ward WS (2003) Ability of hamster spermatozoa to digest their own DNA. Biol Reprod. 69(6):2029-35. Sotolongo B, Huang TT, Isenberger E, Ward WS (2005) An endrogenous nuclease in hamster, mouse, and human spermatozoa cleaves DNA into loop-sized fragments. J Androl. 26(2):272-8
Stieglitz, Lael (2007-present)	None
Squires, JE (2003-present)	Squires JE, Sun J, Caffrey JL, Yoshishige D, Mallet RT. (2003) Acetoacetate augments beta-adrenergic inotropism of stunned myocardium by an antioxidant mechanism. Am J Physiol Heart Circ Physiol. 284:H1340-7 Mutsvangwa T, Gilmore J, Squires JE, Lindinger MI, McBride BW. (2004) Chronic metabolic acidosis increases mRNA levels for components of the ubiquitin-mediated proteolytic pathway in skeletal muscle of dairy cows. J Nutr. 134:558-61.
Stieglitz, Lael (2007-present)	None
Szauter, Kornelia (2001-2006)	Molnar J, Fong KS, He QP, Hayashi K, Kim Y, Fong SF, Fogelgren B, Szauter KM, Mink M, Csiszar K. (2003) Structural and functional diversity of lysyl oxidase and the LOX-like proteins. Biochim Biophys Acta. 1647:220-4. Li PA, He Q, Cao T, Yong G, Szauter KM, Fong KS, Karlsson J, Keep MF, Csiszar K. (2004) Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis. Brain Res Mol Brain Res. 120:115-22. Fogelgren B, Polgar N, Szauter KM, Ujfaludi Z, Laczko R, Fong KS, Csiszar K. (2005) Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. J Biol Chem. 280:24690-7.
Takeuchi, KK (2002-present)	Kanemaru KK, Tuthill MC, Takeuchi KK, Sidell N, Wada RK(2007) Retinoic acid induced downregulation of MYCN is not mediated through changes in Spl/Sp3. Tuthill MC, Wada RK, Arimoto JM, Sugino CN, Kanemaru KK, Takeuchi KK, Sidell N.  N-myc oncogene expression in neuroblastoma is driven by Sp1 and Sp3.  Mol Genet Metab 80:272-280, 2003.
Tarnay(Cogbill), J (2001-present)	Tarnay, J.   Tarnay JN, F. Szeri, A. Iliás, T. Annilo, C. Sung, O. Le Saux, A. Váradi, M. Dean, C.D. Boyd, and S. Robinow (2004). The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.  Insect Molecular Biology Oct;13(5):539-4
Teeters, Kelsa (2004-present)
Urschitz, J (1999-2005)	Stollberg J, Urschitz J, Urban Z, Boyd CD (2000) A quantitative evaluation of SAGE. Genome Res. 10(8):1241-8. Urschitz J, Iobst S, Urban Z, Granda C, Souza KA, Lupp C, Schilling K, Scott L, Csiszar K, Boyd CD. (2002) A serial analysis of gene expression in sun-damaged human skin. J Invest Dermatol. 1 19(1):3-13. O’Riordan DL, Lunde KB, Urschitz J, Glanz K (2005) A noninvasive objective measure of sunscreen use and reapplication. Cancer Epidemiol Biomarkers. 14(3):722-6.
Valliere, Justin (2007-present)	Coe N, Valliere J M (2007) Nature and Nurture in the New england Forest. Iowa Press (Invited)
Wong, Mayee (2004-present)
Young-Robbins, SS (2005-present)	Borthakur PB, Orozco CC, Young-Robbins SS, Haselkorn R, Callahan SM. (2005) Inactivation of patS and hetN causes lethal levels of heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. 7120 Mol Microbiol. 57:111-23.
Zhou, Dan (2006-present)

 

 

7. What attempts are made to monitor student post-graduate professional activities?

The graduate division at the University of Hawaii monitors post-graduate activities for all graduate programs. We do not have a formal program of surveying graduates of CMB, but plan to implement one. Faculty mentors typically hear form the former students via attendance at meetings, phone calls and e-mails. 

In which industries/professions do your graduates find employment? 

The CMB program and its predecessors, the programs in Biomedical Sciences and Genetics have graduated approximately 60 M.S. students and 60 Ph.D. students since 1991. Graduates have gone to postdoctoral and academic positions at institutions on the mainland and abroad, and to positions in industry including in Hawaii and on the mainland. While we do not have specific numbers for CMB graduates, overall, UH has higher than national average levels of graduates going on to postdoctoral fellowships (22 vs 16%), to positions supported by the federal government (44 vs 29%), to academic appointments (54 vs 53%), and to research and development (58 vs 41%). 

How successful are your graduates in their chosen professions and careers? 

As the CMB graduate program is only in its 6^th year, it is too early to assess the success rates of its graduates. We are currently attempting to track our former students, both for WASC assessment and for applications for training grants.  

8. How were the assessment data/results used to inform decisions concerning the curriculum and administration of the program?

– Was pedagogy changed? 

      Yes.  We have attempted to keep up with the changing demands made on Cell and Molecular Biology faculty.  We teach preparation of PowerPoint presentations, use of WebCT, productive web searching, and other modern techniques to our students. We have also implemented graduate program retreats where advanced-to-candidacy PhD students give oral presentations. 

• Did you make administrative changes?

 

      Yes.  A new graduate student advising and development committee serves the functions of advising students on rotations and other aspects of their research career, as well as organizing an orientation for incoming students and retreats for advanced students to have the opportunity to present their work.  

            – Were there changes in interactions with students? Advising, counseling, etc. 

      Yes.  Incoming students meet with the graduate program chair and are directed to the student advisory and development committee. Students are also provided with a copy of the graduate student handbook and rotation descriptions to assist in identifying laboratories for their research rotations.  

  – Were degree requirements changed? 

      Yes.  For example, a course in Ethics in Biomedical Research was added as a requirement for the PhD degree, reflecting the need for training in how to plan and carry out basic and translational research, regulations involving animals and human subjects, and other essential information for the new researcher. 

  – Were courses changed? 

      With respect to course content, there is some change every year, as dictated by new knowledge.  As noted above, changes in core curriculum have been made to reflect the changing teaching demands made on our graduates.  Some courses are no longer offered, and new ones have been added to reflect changing student demand.   

9. Has the program developed learning outcomes? Please indicate yes or no.

10. Has the program published learning outcomes? Please indicate yes or no.

11. If so, please indicate how the program has published learning outcomes.

12. What evidence is used to determine achievement of student learning outcomes?

13. Who interprets the evidence?

14. What is the process of interpreting the evidence?

15. Indicate the date of last program review.

Emergency Information  |  A-Z Index  |  Contact Us  |  Feedback

©2019 University of Hawaiʻi at Mānoa · 2500 Campus Road · Honolulu, HI 96822 · (808) 956-8111